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Hepatocytes produce TNF-α following hypoxia-reoxygenation and liver ischemia-reperfusion in a NADPH oxidase- and c-Src-dependent manner.
Cell line studies have previously demonstrated that hypoxia-reoxygenation (H/R) leads to the production of NADPH oxidase 1 and 2 (NOX1 and NOX2)-dependent reactive oxygen species (ROS) required for th...Read More
Folate grafted Prussian Blue entrapped with gadolinium(III) as a new contrast agent for tumor-targeted magnetic resonant imaging.
A new generation of magnetic resonant imaging (MRI) contrast agents will simultaneously possess characteristics of high relaxivity, biotargeting ability and nontoxicity, referring that they are helpfu...Read More
Poly(lactic-co-glycolic acid) encapsulated gadolinium oxide nanoparticles for MRI-based cell tracking.
Superparamagnetic iron oxide particles have proven useful for cell tracking applications by monitoring cell transplantation and migration in living organisms. However, one perceived drawback is that t...Read More
Medical radiation imaging systems employ phosphors such as CaWO4 as X-ray receptor materials. Unfortunately, the conversion efficiencies of these materials are rather low (approx. 5%). Alternatives th...Read More
Engineered nanoparticles (NPs) can produce negative impacts on human health even in low doses. In this study, Gd2O3 nanoparticles were synthesized via the polyol route and coated with silicon to form ...Read More
Multifunctional beta-NaGdF4:Yb3+/Er3+ nanoparticles (NPs) were successfully synthesized using oleylamine as both solvent and stabilizer via the thermolysis method. They have uniform morphology with a ...Read More
Gadolinium-loaded chitosan nanoparticles as magnetic resonance imaging contrast agents for the diagnosis of tumor.
The aim of our study was to prepare gadolinium loaded chitosan nanoparticles (Gd-CSNPs) for magnetic resonance imaging (MRI). The chitosan nanoparticles (CSNPs) were prepared by ionic gelation method ...Read More
Future clinical trials investigating the natural history and treatment of femoroacetabular impingement (FAI) will require multimodal staging systems for hip osteoarthritis because the optimal system w...Read More
Active cardiac sarcoidosis: first clinical experience of simultaneous positron emission tomography--magnetic resonance imaging for the diagnosis of cardiac disease.
The purpose of this review is to illustrate various applications of gadofosveset trisodium in evaluating abdominal and peripheral vascular disease. The basic properties, technical considerations, and ...Read More
Evaluation of pediatric thoracic disorders: comparison of unenhanced fast-imaging-sequence 1.5-T MRI and contrast-enhanced MDCT.
The purpose of this study was to investigate the efficacy of thoracic MRI with fast imaging sequences without contrast administration at 1.5 T for evaluating thoracic abnormalities by comparing MRI fi...Read More
Iodinated contrast agent for CT has a short half-life in the vasculature. As the field of interventional procedures expands, a more durable contrast agent would be highly useful. Our study investigate...Read More
Teaching NeuroImages: "Pancake-like" gadolinium enhancement suggests compressive myelopathy due to spondylosis.
A 41-year-old man developed progressive bilateral hand weakness and spastic paraparesis. MRI demonstrated cord edema and "pancake-like" gadolinium enhancement (figure). Inflammatory/neoplast...Read More
Cardiac magnetic resonance imaging in a patient with amniotic fluid embolism associated with severe cardiopulmonary complications.
Amniotic fluid embolism (AFE) is a rare but devastating complication of pregnancy. Acute circulatory failure and obstetric disseminated intravascular coagulopathy are often associated with AFE and lea...Read More
Optimization of high flip angle for late gadolinium enhancement magnetic resonance imaging by phase-sensitive inversion recovery sequence.
This study focuses on optimization of the flip angle (FA) of phase-sensitive inversion recovery (PSIR) reconstruction (PSIR-FA) to achieve improved tissue contrast. Intensity normalization removes the...Read More
Free-breathing, motion-corrected late gadolinium enhancement is robust and extends risk stratification to vulnerable patients.
Background- Routine clinical use of novel free-breathing, motion-corrected, averaged late-gadolinium-enhancement (moco-LGE) cardiovascular MR may have advantages over conventional breath-held LGE (bh-...Read More
Recent attention has been paid to the -cerebrospinal fluid (CSF) dynamics between the intracranial subarachnoid space (SAS) and the SAS around the optic nerve (ON-SAS). We experienced three patients w...Read More
Decrease in the apparent diffusion coefficient in peritumoral edema for the assessment of recurrent glioblastoma treated by bevacizumab.
Anti-edema effect of bevacizumab was evaluated using the apparent diffusion coefficient (ADC) of peritumoral edema associated with regional cerebral blood flow (rCBV) of the tumor.Nine patients with r...Read More
Indirect magnetic resonance lymphography of the head and neck of dogs using Gadofluorine M and a conventional gadolinium contrast agent: a pilot study.
The purpose of this pilot study was to evaluate lymph node enhancement with an indirect magnetic resonance (MR) lymphography technique using 2 different contrast agents in the head and neck region of ...Read More
In vivo magnetization transfer and diffusion-weighted magnetic resonance imaging detects thrombus composition in a mouse model of deep vein thrombosis.
Background- Deep vein thrombosis remains a major health problem necessitating accurate diagnosis. Thrombolysis is associated with significant morbidity and is effective only for the treatment of unorg...Read More
A bi-center cardiovascular magnetic resonance prognosis study focusing on dobutamine wall motion and late gadolinium enhancement in 3,138 consecutive patients.
The first goal of this study is to compare gadofosveset trisodium--a gadolinium agent that reversibly binds to albumin--to an extracellular contrast agent (Gd-DOTA) for the detection of multiple scler...Read More
We investigated the evolution of new multiple sclerosis (MS) lesions over time using frequency shifts of the magnetic resonance (MR) signal.Twenty patients with relapsing-remitting MS were serially sc...Read More
Since 1981, when multiple sclerosis (MS) lesions were first visualized in vivo using MRI, our understanding of MS disease processes has expanded dramatically. Serial postcontrast imaging shows that MS...Read More
[Amyloid beta-related angiitis: brain lesions showing leptomeningeal gadolinium enhancement on MRI and characteristic surgical pathologic features].
Amyloid-β-related angiitis (ABRA) of the CNS occurs in association with vasculitis of small-and medium-sized leptomeningeal arteries. Here, we describe the clinicopathological features of a 76-year-o...Read More