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吲哚

产品编号 I104725 | CAS号 120-72-9 | 阿拉丁
Indole
CP,98%
组合的产品项目
货号 规格 库存 价格 数量
I104725-100g CP,98% 上海(1)
北方(预计3-5个工作日)
 
I104725-25g CP,98% 上海(预计3-7周)
北方(预计3-7周)
 
I104725-500g CP,98% 上海(4)
北方(预计3-5个工作日)
 
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属性

敏感性 对光敏感
折光率 1.609
密度 1.2200
熔点 52.5°C
沸点 254°C

描述

产品介绍 有粪臭,但稀释后有愉快香味。具有强烈的粪臭味,高度稀释的溶液有香味,暴露于空气及光线中则变红色。能随水蒸气挥发。溶于热水、热乙醇、乙醚、苯和石油醚。
别名 吲哚 ;氮茚, 2,3-苯并吡咯,苯并吡咯;1H-Benzo[b]pyrrole
应用 检定金、钾和亚硝酸盐,制造茉莉型香料。制药工业。
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标识符号 GHS05 GHS05, GHS06 GHS06, GHS09 GHS09
信号词 Danger
风险声明 (欧洲) R41;R21/22;R37/38;R50/53
安全声明(欧洲) S26;S36/37/39;S61
警示性声明 P261,P273,P280,P305+P351+P338,P312
危害码(欧洲) Xn,N
危害声明 H302,H311,H315,H318,H335,H400
个人防护设备 dust mask type N95 (US),Eyeshields,Faceshields,Gloves
RTECS NL2450000
WGK德国 1
Merck Index 4963
闪点(摄氏) 136℃
UN代码 2811
参考文献
Masaaki Fujikawa, Kazuya Nakao, Ryo Shimizu, Miki Akamatsu
To investigate PAMPA permeability of hydrophobic compounds, we experimentally measured the P"a"p"p"-"p"a"m"p"a of compounds with high hydrophobicity, inclu...Read More
Alan P Graves, Ruth Brenk, Brian K Shoichet
Molecular docking is widely used to predict novel lead compounds for drug discovery. Success depends on the quality of the docking scoring function, among other factors. An imperfect scoring function ...Read More
Aleem Gangjee, Nilesh Zaware, Ravi Kumar Vyas Devambatla, Sudhir Raghavan, Cara D Westbrook, Nicholas F Dybdal-Hargreaves, Ernest Hamel, Susan L Mooberry
A series of fourteen N(4)-(substituted phenyl)-N(4)-alkyl/desalkyl-9H-pyrimido[4,5-b]indole-2,4-diamines was synthesized as potential microtubule targeting agents. The synthesis involved a Fisher indo...Read More
C Baes, S Mattei, H Luther, S Ampuero, X Sidler, G Bee, P Spring, A Hofer
Genetically reducing boar taint using low-taint lines is considered the most sustainable and economic long-term alternative to surgical castration of male pigs. Owing to the high heritability of the m...Read More
Albert Sánchez, Enrique Pedroso, Anna Grandas
Aggregated amyloid-beta (Abeta) peptide is implicated in the pathology of Alzheimer's disease. In vitro and in vivo, these aggregates are found in a variety of morphologies, including globular ol...Read More
Rui Wang, Hong-Fan Shi, Jing-Feng Zhao, Yan-Ping He, Hong-Bin Zhang, Jian-Ping Liu
A series of novel indole-imidazole derivatives have been prepared and evaluated in vitro on the aromatase inhibitory activities. The results suggested that proton or a small electron-withdrawing group...Read More
Xianchang Li, Jianxin Li, Wei Li, Xiaodong Zhou, Qianqian Li, Zhen Li, Jingui Qin, Jiming Hu
In this essay, three novel nonlinear optical (NLO) azo-materials containing indole and sulfonyl based chromophores were studied in-depth by using Fourier transform (FT) IR, FT-Raman spectra and densit...Read More
Nadeesha Ranasinghe, Graham B Jones
Microwave, flow and combination methodologies have been applied to the synthesis of a number of substituted indoles. Based on the Hemetsberger-Knittel (HK) process, modifications allow formation of pr...Read More
Stephen J Heffernan, James M Beddoes, Mary F Mahon, Alan J Hennessy, David R Carbery
The Au(I)-catalysed rearrangement of propargylic esters formed from an ynamide has been studied. The reaction is facile, and when conducted in the presence of a reactive indole nucleophile, leads to a...Read More
Gang Li, Kevin D Young
The signalling molecule indole occurs in significant amounts in the mammalian intestinal tract and regulates diverse microbial processes, including bacterial motility, biofilm formation, antibiotic re...Read More
Thomas B Parsons, Neil Spencer, Chi W Tsang, Richard S Grainger
The first synthesis of kottamide E, a marine natural product containing a 5,6-dibromoindole linked via a (Z)-enamide to an unusual 1,2-dithiolane-containing amino acid, is reported....Read More
Catalin Chimerel, Andrew J Murray, Enno R Oldewurtel, David K Summers, Ulrich F Keyser
Indole is an important biological signalling molecule produced by many Gram positive and Gram negative bacterial species, including Escherichia coli. Here we study the effect of indole on the electric...Read More
Ricardo Valladares, Lora Bojilova, Anastasia H Potts, Evan Cameron, Christopher Gardner, Graciela Lorca, Claudio F Gonzalez
In our previous work, we found that feeding Lactobacillus johnsonii to BioBreeding diabetes-prone (BBDP) rats decreased the incidence of diabetes development. The aim of this study was to investigate ...Read More
Israel Alvarado, Andy Phui, Michelle M Elekonich, Ernesto Abel-Santos
Paenibacillus larvae is the causative agent of American foulbrood (AFB), a disease affecting honey bee larvae. First- and second-instar larvae become infected when they ingest food contaminated with P...Read More
Yuanhong Ma, Jingsong You, Feijie Song
Well-connected: The palladium-catalyzed addition of indoles to nitriles affords 3-acylindoles. The reaction proceeds with high selectivity, wide substrate scope, broadly available starting materials, ...Read More
Xueqing Geng, Jiye Cheng, Anju Gangadharan, David Mackey
The phytotoxin coronatine (COR) promotes various aspects of Pseudomonas syringae virulence, including invasion through stomata, growth in the apoplast, and induction of disease symptoms. COR is a stru...Read More
Kap-Sun Yeung, Zhilei Qiu, Quifen Xue, Haiquan Fang, Zheng Yang, Lisa Zadjura, Celia J D'Arienzo, Betsy J Eggers, Keith Riccardi, Pei-Yong Shi, Yi-Fei Gong, Marc R Browning, Qi Gao, Steven Hansel, Kenneth Santone, Ping-Fang Lin, Nicholas A Meanwell,
A series of substituted carboxamides at the indole C7 position of the previously described 4-fluoro-substituted indole HIV-1 attachment inhibitor 1 was synthesized and the SAR delineated. Heteroaryl c...Read More
Kap-Sun Yeung, Zhilei Qiu, Zhiwei Yin, Ashok Trehan, Haiquan Fang, Bradley Pearce, Zheng Yang, Lisa Zadjura, Celia J D'Arienzo, Keith Riccardi, Pei-Yong Shi, Timothy P Spicer, Yi-Fei Gong, Marc R Browning, Steven Hansel, Kenneth Santone, Jonathan Bar
As part of the SAR profiling of the indole-oxoacetic piperazinyl benzamide class of HIV-1 attachment inhibitors, substitution at the C7 position of the lead 4-fluoroindole 2 with various 5- and 6-memb...Read More
Vida Mashayekhi, Kamaleddin Haj Mohammad Ebrahim Tehrani, Salimeh Amidi, Farzad Kobarfard
Based on the existing reports regarding the antiplatelet aggregation activity of hydrazone derivatives, a series of indole hydrazone derivatives were considered as potential antiplatelet agents and sy...Read More
Masaru Enomoto, Akira Morita, Shigefumi Kuwahara
Succinct and stereoselective: A high-yielding two-step indole ring installation comprising the Stille cross-coupling and a Pd(II) -mediated oxidative heterocyclization was exploited in a concise total...Read More
Nirod Kumar Sarangi, Archita Patnaik
Molecular orientation-dependent electron transport across supported 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) lipid bilayers (SLBs) on semiconducting indium tin oxide (ITO) is reported with a...Read More
Mattia Mori, Cristina Tintori, Robert Selwyne Arul Christopher, Marco Radi, Silvia Schenone, Francesca Musumeci, Chiara Brullo, Patrizia Sanità, Simona Delle Monache, Adriano Angelucci, Miroslava Kissova, Emmanuele Crespan, Giovanni Maga, Maurizio Botta
Pim-1 is a serine/threonine kinase critically involved in the initiation and progression of various types of cancer, especially leukemia, lymphomas and solid tumors such as prostate, pancreas and colo...Read More
Shengnan Shi, Fang Ma, Tieheng Sun, Ang Li, Jiti Zhou, Yuanyuan Qu
Biotransformation of indole to indigo in liquid-liquid biphasic systems was performed in Escherichia coli cells expressing phenol hydroxylase. It was suggested that indole could inhibit the cell growt...Read More
Fuxu Zhan, Guangxin Liang
Cut to the chase: Direct formation of an enehydrazine, an intermediate in the classic Fischer indole synthesis, solves the regioselectivity problem associated with indolization. This approach not only...Read More
Benjamin Suenkel, Frank Fischer, Clemens Steegborn
Sirtuins are NAD(+) consuming protein deacylases involved in many cellular processes from DNA-repair to metabolism. Their contribution to age-related and metabolic diseases makes them attractive pharm...Read More
Rodolphe Beaud, Régis Guillot, Cyrille Kouklovsky, Guillaume Vincent
IRONic electrophilic indoles! The C3-regioselective hydroarylation of N-acetyl indoles with aromatic nucleophiles mediated by FeCl(3) features a rare example of the electrophilic reactivity of the in...Read More
Huijun H Dong, Chris C Limberakis, Spiros S Liras, David D Price, Keith K James
A highly efficient macrocyclization reaction has been developed via the palladium-catalyzed C-H arylation of the side-chains of tryptophan with halophenyl-containing amino acids. This method allows fo...Read More
Zsolt Z Székelyhidi, János J Pató, Frigyes F Wáczek, Péter P Bánhegyi, Bálint B Hegymegi-Barakonyi, Dániel D Er?s, Gy?rgy G Mészáros, Ferenc F Hollósy, Doris D Hafenbradl, Sabine S Obert, Bert B Klebl, Gy?rgy G Kéri, László L Orfi
SR protein-specific kinase-1 (SRPK-1) has been identified as a validated target for hepatitis B virus (HBV). A series of novel tricyclic quinoxaline derivatives was designed and synthesised as potenti...Read More
Origène Nyanguile, Frederik Pauwels, Walter Van den Broeck, Carlo W Boutton, Ludo Quirynen, Tania Ivens, Liesbet van der Helm, Geneviève Vandercruyssen, Wendy Mostmans, Frédéric Delouvroy, Pascale Dehertogh, Maxwell D Cummings, Jean-Francois Bonfanti, Ken
The exogenous control of hepatitis C virus (HCV) replication can be mediated through the inhibition of the RNA-dependent RNA polymerase (RdRp) activity of NS5B. Small-molecule inhibitors of NS5B inclu...Read More
Deniz D Ekinci, Hüseyin H Cavdar, Serdar S Durdagi, Oktay O Talaz, Murat M Sentürk, Claudiu T CT Supuran
Several 5,10-dihydroindeno[1,2-b]indole derivatives incorporating methoxy, hydroxyl, and halogen (F, Cl, and Br) moieties on the indene fragment of the molecule were prepared and tested against five c...Read More