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N-甲基吡咯烷酮(NMP)

产品编号 M100588 | CAS号 872-50-4 | Aladdin
1-Methyl-2-pyrrolidinone
AR,>99.0%(GC)
组合的产品项目
货号 规格 库存 价格 数量
M100588-10L AR,>99.0%(GC) 上海(>10)
北方(预计3-5个工作日)
 
M100588-2.5L AR,>99.0%(GC) 上海(>10)
北方(预计3-5个工作日)
 
M100588-500ml AR,>99.0%(GC) 上海(>10)
北方(预计3-5个工作日)
 
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属性

敏感性 对水分敏感,充氩气保存
折光率 1.47
密度 1.0280
熔点 -24°C
沸点 81-82°C
存贮条件 易吸潮,密封避光保存。

描述

产品介绍 微有胺的气味。能与水、醇、醚、酯、酮、卤代烃、芳烃和蓖麻油互溶。挥发度低,热稳定性、化学稳定性均佳,能随水蒸气挥发。有吸湿性。对光敏感。半数致死量(大鼠,经口)3.8ml/kg。
别名 N-甲基吡咯烷酮(NMP) ;1-甲基吡咯烷酮,NMP溶剂,1-甲基-2-吡咯烷酮,二异丙基酮,N-甲基-A-吡咯烷酮 ;1-Methyl-2-pyrrolidone N-Methyl-2-pyrrolidone M-PYROL™ NMP
应用 用作溶剂及萃取剂。
NMP是一种极性的非质子传递溶剂,具有毒性小,沸点高,溶解能力出众,选择性强和稳定性好的优点。广泛用于芳烃萃取;乙炔、烯烃、二烯烃的纯化。也用于聚合物的溶剂及聚合反应的介质要。如聚酰胺、聚酰亚胺、聚苯硫醚等工程塑料及芳纶纤维。另外还用于绝缘材料、农药、颜料及清洁剂等方面。
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标识符号 GHS07 GHS07, GHS08 GHS08
信号词 Danger
风险声明 (欧洲) R36/38
安全声明(欧洲) S41
警示性声明 P201,P261,P305+P351+P338,P308+P313
危害码(欧洲) Xi
危害声明 H315,H319,H335,H360
个人防护设备 Eyeshields,full-face respirator (US),Gloves,multi-purpose combination respirator cartridge (US),type ABEK (EN14387) respirator filter
RTECS UY5790000
WGK德国 1
闪点(摄氏) 91 °C
UN代码 1760
参考文献
Jih-Jung JJ Chen, Chang-Syun CS Yang, Chien-Fang CF Peng, Ih-Sheng IS Chen, Chang-Ling CL Miaw
Four new compounds, including two new dihydroagarofuranoid sesquiterpenes, 8-benzoyloxymutangin (1) and 15-acetoxyorbiculin G (2), a new lignan derivative, 9,9'- O-di-(Z)-feruloyl-(-)-secoisolari...Read More
Chun-Wa CW Chung, Anthony W AW Dean, James M JM Woolven, Paul P Bamborough
Bromodomain-containing proteins are key epigenetic regulators of gene transcription and readers of the histone code. However, the therapeutic benefits of modulating this target class are largely unexp...Read More
Stephen R Adams, Roger Y Tsien
The membrane-permeant fluorogenic biarsenicals FlAsH-EDT(2) and ReAsH-EDT(2) can be prepared in good yields by a straightforward two-step procedure from the inexpensive precursor dyes fluorescein and ...Read More
Seung-Deok Seo, Yun-Ho Jin, Seung-Hun Lee, Hyun-Woo Shim, Dong-Wan Kim
In this study, we report the high-yield synthesis of 2-dimensional cupric oxide (CuO) nanodiscs through dehydrogenation of 1-dimensional Cu(OH)2 nanowires at 60°C. Most of the nanodiscs had a diamete...Read More
W Schloegl, V Marschall, M Y Witting, E Volkmer, I Drosse, U Leicht, M Schieker, M Wiggenhorn, F Schaubhut, S Zahler, W Friess
Goal of the present study was to develop and to characterize in situ-hardening, porous PLGA-based systems for their future application as bone grafting materials. Therefore, we investigated the precip...Read More
Thomas L TL Eberhardt, Stan S Lebow, Karen G KG Reed
A cellulose solvent system based on lithium chloride (LiCl) in N-methyl-2-pyrrolidinone (NMP) was used to assess the merits of partial dissolutions of coarsely ground wood samples. Alkaline Copper Qua...Read More
Eleri Wallace, Charlene M Y Ong, Charles M Heard
Malarone(?), a combination of atovaquone (AT) and proguanil (PR), is indicated for the prophylaxis and treatment of uncomplicated Plasmodium falciparum malaria. This study aimed to determine in vitro ...Read More
Luis Solorio, Brett M Babin, Ravi B Patel, Justyna Mach, Nami Azar, Agata A Exner
In situ forming drug delivery systems provide a means by which a controlled release depot can be physically inserted into a target site without the use of surgery. The release rate of drugs from these...Read More
Geoff J Dumsday, Gunseli Ocal, John S Bridger, Michael Zachariou
Arising from the requirement for discovery of novel biocatalysts with unusual properties, a process was developed which uniquely combines aspects of continuous culture with the measurement of oxygen u...Read More
Petra P Sázelová, Václav V Kasicka, Dusan D Koval, Zdenek Z Prusík, Salvatore S Fanali, Zeineb Z Aturki
Various ways of application of radial electric field for the control of electrokinetic potential and EOF in a home-made device for CE are presented. The device comprises three high-voltage power suppl...Read More
Laura L Vogelaar, Rob G H RG Lammertink, Jonathan N JN Barsema, Wietze W Nijdam, Lydia A M LA Bolhuis-Versteeg, Cees J M CJ van Rijn, Matthias M Wessling
Phase separation micromolding (PSmicroM) is a versatile microfabrication technique that can be used to structure a very broad range of polymers, including block copolymers and biodegradable and conduc...Read More
T J TJ Morgan, A A AA Herod, S A SA Brain, F M FM Chambers, R R Kandiyoti
Soil from a redundant coke oven site has been examined by extraction of soluble materials using 1-methyl-2-pyrrolidinone (NMP) followed by size exclusion chromatography (SEC) of the extracted material...Read More
Richard R Thomas
Contact angle relaxation studies were performed on a base hydrolyzed PMDA-ODA polyimide surface using methanol, pyridine and 1-methyl-2-pyrrolidinone (NMP) as probe liquids. The results were fitted pa...Read More
B B Purevsuren, B B Avid, Ya Y Davaajav, A A AA Herod, R R Kandiyoti, T J TJ Morgan
Casein has been pyrolysed to obtain a biochar (28.3% yield), with mostly meso- and macro-pore structure, and a liquid tar product of high yield (37.5%) with the balance as gas (20.9%) and water (13.3%...Read More
Jean-Paul JP Payan, Dominique D Beydon, Jean-Paul JP Fabry, Isabelle I Boudry, Benoit B Cossec, Elisabeth E Ferrari
This study evaluated the toxicokinetics of N-[(14)C]methylpyrrolidone ([(14)C]NMP) after intravenous administration (0.1, 1, 10, 100, and 500 mg/kg, in saline solution) or topical application (20 and ...Read More
Peter Akrill, John Cocker, Steve Dixon
N-methyl pyrrolidone (NMP) is a substance widely used for its strong and selective solvent capacity. The strong potential NMP has for skin absorption makes biological monitoring ideal for exposure ass...Read More
J V JV Headley, K M KM Peru, D A DA Friesen, T T Neu
A rugged procedure utilizing reversed-phase liquid chromatography with positive-ion electrospray ionization mass spectrometry (LC-MS) along with tandem MS is described for the quantification and confi...Read More
G G Engelhardt, H H Fleig
1-Methyl-2-pyrrolidinone induces aneuploidy in yeast, but only under special treatment conditions. Other genotoxic effects have not been found in vitro, and in vivo no data are available in the litera...Read More
M Sodicoff, A Lamperti, M C Ziskin
Radioprotectors are not currently used clinically due to concerns regarding toxicity and uncertainties regarding tumor protection. Topical radioprotection of skin might find clinical applications with...Read More
C J CJ Bagley, K M KM Otteson, B L BL May, S N SN McCurdy, L L Pierce, F J FJ Ballard, J C JC Wallace
Insulin-like growth factor I (IGF-I), a protein of 70 amino acid residues and 3 cystine bridges, has been synthesized by two solid phase Boc methods. The first method used N-methylpyrrolidinone as the...Read More
Nitin Wasantrao NW Fadnavis, Ramanujam R Seshadri, Gurrala G Sheelu, Kallakunta Vasantha KV Madhuri
Effects of cosolvent concentration on activity of fire fly luciferase, @a-chymotrypsin, and alcohol dehydrogenase from baker's yeast (Saccharomyces cerevisiae) have been studied for several solve...Read More
K J KJ Brodbeck, J R JR DesNoyer, A J AJ McHugh
The role of solvent properties and bath-side composition on the phase inversion dynamics and in vitro protein release kinetics of polylactic-co-glycolic acid (PLGA) solutions has been examined using d...Read More
B A BA J?nsson, B B Akesson
A method for simultaneous determination of 5-hydroxy-N-methylpyrrolidone and 2-hydroxy-N-methylsuccinimide in urine is described. These compounds are metabolites of N-methyl-2-pyrrolidone, a powerful ...Read More
David S Hewings, Minghua Wang, Martin Philpott, Oleg Fedorov, Sagar Uttarkar, Panagis Filippakopoulos, Sarah Picaud, Chaitanya Vuppusetty, Brian Marsden, Stefan Knapp, Stuart J Conway, Tom D Heightman
Histone-lysine acetylation is a vital chromatin post-translational modification involved in the epigenetic regulation of gene transcription. Bromodomains bind acetylated lysines, acting as readers of ...Read More

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