|别名||4,4'-四甲基二氨基二苯甲烷 ;4,4'-双二甲氨基代二苯甲烷，4,4'-甲撑双（二甲苯胺）,甲烷贝司 ;N,N,N′,N′-Tetramethyl-4,4′-methylenedianiline N,N,N′,N'-Tetramethyl-4,4'-diaminodiphenylmethane Arnolds base 4,4'-Tetramethyldiaminodiphenyl methane Bis[4-(dimethylamino)phenyl]methane 4,4'-Methylenebis(N,N-dimethylaniline) Methane Base Tetra Base|
|个人防护设备||Eyeshields,full-face particle respirator type N100 (US),Gloves,respirator cartridge type N100 (US),type P1 (EN143) respirator filter,type P3 (EN 143) respirator cartridges|
DNA fragmentation and DNA repair synthesis induced in rat and human thyroid cells by four rat thyroid carcinogens
Four chemicals that are known to induce in rats thyroid follicular-cell adenomas and carcinomas were assayed for their ability to induce DNA damage and DNA repair synthesis in primary cultures of huma...Read More
Reaction of 2-hydroxydeoxybenzoins with bis(dimethylamino)methane in ethanol results in isoflavonones....Read More
Morphology of the neoplasms of the thyroid gland in Fischer 344 rats treated with 4,4'-methylene-bis-(N,N-dimethyl)-benzenamine.
Follicular neoplasms of the thyroid gland developed in 79 of 200 Fischer 344 rats of both sexes, fed either 0.0375% or 0.075% 4,4'-methylene-bis-(N,N-dimethyl)-benzenamine (MDBA) mixed with the d...Read More
Studies on the in vivo and in vitro disposition of 4,4'-[14C]-methylenebis(N,N-dimethyl)benzamine (reduced Michler's ketone, RMK) were performed. Osborne-Mendel rats retained, after 24 hr, 7...Read More
This paper confirms the mutagenicity of 2 carcinogenic chemicals, o-tolidine and 4,4'-tetramethyldiaminodiphenylmethane (TDDM). o-Tolidine and TDDM were both tested in the Salmonella/mammalian-mi...Read More
A comparison of the mutagenicity and macromolecular binding of the carcinogens Michler's ketone and reduced Michler's ketone.
The mutagenicity of 4,4'-bis(dimethylamino)benzophenone (Michler's ketone, MK, CAS No. 90-94-8) and 4,4'-methylenebis(N,N-dimethyl)benzamine (reduced Michler's ketone, RMK, CAS No....Read More
Binding of the dye intermediates Michler's ketone and methane base to rat liver nucleic acids and lack of mutagenicity in Salmonella typhimurium.
Promotive effect of 4,4'-methylenebis(N,N-dimethyl)benzenamine on N-bis(2-hydroxypropyl)nitrosamine-induced thyroid tumors in Wistar rats.
The promotive effect of 4,4'-methylenebis(N,N-dimethyl)benzenamine (MDBA) on 2-stage thyroid tumorigenesis induced by N-bis(2-hydroxypropyl)nitrosamine (DHPN) in Wistar male rats was investigated...Read More
[Effects of bis(dimethyl amino)-diphenyl methane (BDDM) on action potentials in guinea pig papillary muscle].
The effects of BDDM on action potentials and slow response action potentials in guinea pig papillary muscle were investigated by microelectrode technique. BDDM prolonged action potentials duration at ...Read More
Many a drug was identified by thin layer chromatography when using tetramethyldiaminodiphenylmethan (TDM) as a universal reagent subsequently to chlorination. This non-carcinogenic compound yields a c...Read More