|溶解性||Soluble in water (542 mg/ml at 20 °C), alcohol, methanol (15.5 g/100g at 0 °C), and ethanol (3.61 g/100g at 0 °C).|
|生化机理||Magnesium Chloride is widely used as a source of magnesium ion. In biological systems, magnesium is a co-foactor for many enzymes including deoxyribonuclease (DNase) and various restriction enzymes. Also plays a role in cell membrane integrity, muscle cell physiology, and nucleic acid structure. Magnesium chloride solution is a favorable choice as an elution buffer for antibody affinity column purifications; it is much milder on most antigens than acid elution, allowing reuse of the antigen column. Also an essential cofactor for the DNA polymerase in polymerase chain reaction (PCR) amplification.Hexahydrate form also available: Magnesium Chloride, Hexahydrate.|
|应用||An excellent magnesium ion source for synthesis and biology research.|
Rapid and efficient synthesis of nucleoside polyphosphates and their conjugates using sulfonyl imidazolium salts.
This unit describes a method for preparing nucleoside polyphosphates and their conjugates such as nucleoside triphosphates, symmetrical and unsymmetrical dinucleoside polyphosphates and sugar nucleoti...Read More
Elevated ferric, calcium and magnesium ions in the brain induce protein aggregation in brain mitochondria.
Alzheimer's disease and Parkinson's disease are two of several neurodegenerative disorders that affect the elderly. Although their aetiology remains uncertain, studies suggest that elevated ...Read More
This study investigated the effects of NH(4)Cl and MgCl(2) on pretreatment and xylan hydrolysis of miscanthus straw for biofuels production. It was observed that increasing the pretreatment temperatur...Read More
Trace elements represent a group of essential metals or metaloids necessary for life, present in minute amounts. Analgesic adjuvants can enhance the effect of other pain drugs or be used for pain cont...Read More
[The effectiveness of certain magnesium salts in nephrolithiasis caused by the use of sodium oxalate and celecoxib].
The study was aimed to evaluation the effect of different magnesium salts and their combinations with pyridoxine on a course of calcium-oxalate nephrolithiasis, which was modeled by adding the sodium ...Read More
Differences in photosynthetic performance and its correlation with growth among tomato cultivars in response to different salts.
Previous works into photosynthesis regulation under salt stress have focused on the effect of NaCl, although other salts may significantly contribute to the toxicity of saline soils. In this paper, th...Read More
Meta-analysis of randomized controlled trials on magnesium in addition to beta-blocker for prevention of postoperative atrial arrhythmias after coronary artery bypass grafting.
Atrial arrhythmia (AA) is the most common complication after coronary artery bypass grafting (CABG). Only beta-blockers and amiodarone have been convincingly shown to decrease its incidence. The effec...Read More
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In this work, we report on how salt concentration and cation species affect DNA translocation in voltage-biased silicon nitride nanopores. The translocation of dsDNA in linear, circular, and supercoil...Read More
Investigation into the controversial association of Streptococcus gallolyticus with colorectal cancer and adenoma.
The seroprevalence of IgG antibodies of Streptococcus gallolyticus subspecies gallolyticus, CIP 105428, was evaluated to investigate the controversial association of S. gallolyticus with colorectal ca...Read More
Cation-dependent folding of 3' cap-independent translation elements facilitates interaction of a 17-nucleotide conserved sequence with eIF4G.
The 3'-untranslated regions of many plant viral RNAs contain cap-independent translation elements (CITEs) that drive translation initiation at the 5'-end of the mRNA. The barley yellow dwarf...Read More
Squid have nociceptors that display widespread long-term sensitization and spontaneous activity after bodily injury.
Bodily injury in mammals often produces persistent pain that is driven at least in part by long-lasting sensitization and spontaneous activity (SA) in peripheral branches of primary nociceptors near s...Read More
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Understanding the influence of water layers adjacent to interfaces is fundamental in order to fully comprehend the interactions of both biological and nonbiological materials in aqueous environments. ...Read More
Effects of proteoliposome composition and draw solution types on separation performance of aquaporin-based proteoliposomes: implications for seawater desalination using aquaporin-based biomimetic membranes.
Aquaporins are a large family of water transport proteins in cell membranes. Their high water permeability and solute rejection make them potential building blocks for high-performance biomimetic memb...Read More
Analogous to the biologically abundant protein-based linear molecular machines that translocate along their target surface, we have recently constructed the DNA-based synthetic molecular motors that e...Read More
Divalent Cations Enhance Fluoride Binding to Streptococcus mutans and Streptococcus sanguinis Cells and Subsequently Inhibit Bacterial Acid Production.
One preventive effect of topical fluoride application is derived from the fact that fluoride can inhibit bacterial acid production. Furthermore, divalent cations such as Ca(2+) and Mg(2+) increase the...Read More
The nucleoid-associated protein Dan organizes chromosomal DNA through rigid nucleoprotein filament formation in E. coli during anoxia.
Dan is a transcription factor that regulates the ttd operon encoding tartrate dehydratase. During anaerobic conditions, its copy number increases by 100-fold, making Dan an abundant nucleoid-associate...Read More
Reducing sodium in food could have an effect on food safety. The objective was to determine differences in growth of Listeria monocytogenes in meat and poultry systems with salt substitutes. For phase...Read More
Acclimation of leaves to low light produces large grana: the origin of the predominant attractive force at work.
Photosynthetic membrane sacs (thylakoids) of plants form granal stacks interconnected by non-stacked thylakoids, thereby being able to fine-tune (i) photosynthesis, (ii) photoprotection and (iii) accl...Read More
Septin forms a conserved family of cytoskeletal GTP-binding proteins that have diverse roles in protein scaffolding, vesicle trafficking and cytokinesis. There are 14 mammalian septin isoforms and the...Read More
Maternal magnesium supplementation reduces intrauterine growth restriction and suppresses inflammation in?a?rat?model.
Intrauterine growth restriction (IUGR) is associated with?increased inflammatory responses. We sought to investigate whether magnesium (Mg) attenuates inflammation and IUGR in a rat model.Pregnant Wis...Read More
Characterization of a Variant of Xanthomonas citri subsp. citri that Triggers a Host-Specific Defense Response.
ABSTRACT Citrus is an economically important fruit crop that is severely afflicted by Asiatic citrus bacterial canker (CBC), a disease caused by the phytopathogen Xanthomonas citri subsp. citri (X. ci...Read More
Characterising protein, salt and water interactions with combined vibrational spectroscopic techniques.
In this paper a combination of NIR spectroscopy and FTIR and Raman microspectroscopy was used to elucidate the effects of different salts (NaCl, KCl and MgSO(4)) on structural proteins and their hydra...Read More
Increased frequency and severity of developmental deformities in rough-skinned newt (Taricha granulosa) embryos exposed to road deicing salts (NaCl & MgCl2).
Road-side aquatic ecosystems in North America are annually polluted with millions of tons of road deicing salts, which threaten the survival of amphibians which live and breed in these habitats. While...Read More
DNA polymerase (pol) β is a model polymerase involved in gap-filling DNA synthesis utilizing two metals to facilitate nucleotidyl transfer. Previous structural studies have trapped catalytic intermed...Read More
Concentration polarization phenomenon during the nanofiltration of multi-ionic solutions: influence of the filtrated solution and operating conditions.
One of the major difficulties for the prediction of separation performances in the case of multi-ionic mixtures nanofiltration lies in the description of the concentration polarization phenomenon. Usu...Read More