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4-硝基氯化苄

产品编号 N100515 | CAS号 100-14-1 | Aladdin
4-Nitrobenzyl chloride
98%
组合的产品项目
货号 规格 库存 价格 数量
N100515-10g 98% 上海(>10)
北方(预计3-5个工作日)
 
N100515-250g 98% 上海(2)
北方(预计3-5个工作日)
 
N100515-50g 98% 上海(2)
北方(预计3-5个工作日)
 
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属性

密度 1.3300
熔点 71-74°C
沸点 112°C
溶解性 不溶于水,溶于乙醇、乙醚,易溶于丙酮、苯。

描述

别名 4-硝基氯化苄 ;4-硝基氯苄,对硝基氯化苄,对硝基苄基氯,对硝基苯氯甲烷,对硝基氯苄 ;α-Chloro-4-nitrotoluene alpha-Chloro-p-nitrotoluene p-Nitrobenzyl chloride
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标识符号 GHS05 GHS05, GHS07 GHS07
信号词 Danger
风险声明 (欧洲) R22;R34
安全声明(欧洲) S26;S36/37/39;S45
警示性声明 P280,P305+P351+P338,P310
危害码(欧洲) C
危害声明 H302,H314
个人防护设备 Eyeshields,Faceshields,full-face particle respirator type N100 (US),Gloves,respirator cartridge type N100 (US),type P1 (EN143) respirator filter,type P3 (EN 143) respirator cartridges
RTECS XS9093000
WGK德国 3
是否危化品 一般危险品
UN代码 3261
参考文献
K Hemminki, K Falck, K Linnainmaa
Benzyl chloride, benzyl bromide, p-methylbenzyl chloride, and p-nitrobenzyl chloride were used to study chemical reactivity with 4-(p-nitrobenzyl)-pyridine (NBP), and with guanosine in vitro, in relat...Read More
S S Giorgini, P P Spallanzani, P P Fabbri, G G Rapi, M M Ginanneschi, A A Sertoli
A case of occupational contact dermatitis in a female chemical pharmaceutical laboratory researcher is described. The allergological investigation revealed a state of sensitization to three mono-nitro...Read More
K K Datta, S K SK Roy, A K AK Mitra, A P AP Kulkarni
Glutathione S-transferase (GST) with activity towards CDNB as a substrate from human intrauterine conceptual tissues (HICT) at 6-10 weeks of gestation was purified approximately 200-fold by GSH couple...Read More
D Mansuy, M Fontecave
We're sorry this abstract is currently not available....Read More
D D Mansuy, M M Fontecave
The benzyl halides benzyl bromide and 4-nitrobenzyl chloride are reduced anaerobically by NADPH and rat liver microsomes to yield toluene and 4-nitrotoluene, respectively. These reductions and cytochr...Read More
S V SV Singh, S K SK Srivastava, Y C YC Awasthi
When rats were orally administered a daily dose of 300 mg kg-1 body weight of 3,5-di-t-butyl-4-hydroxytoluene (BHT) for 4 days, about 90% increase over basal level in total glutathione (GSH) S-transfe...Read More
J J JJ Jaffe, R A RA Lambert
Glutathione S-transferase (EC 2.5.1.18) was detected in the cytosolic and microsomal fractions of adult Dirofilaria immitis females at respective levels of 30 nmol and 3 nmol min-1 (mg protein)-1 acti...Read More
S N SN Moreno, J J Schreiber, R P RP Mason
The o-, m-, and p-nitrobenzyl chlorides are reduced aerobically and anaerobically by NADPH and rat hepatic microsomes. Under aerobic conditions, these nitro anion radicals reduce oxygen to superoxide ...Read More
Shingo S Arakawa, Kazunori K Fujimoto, Ayako A Kato, Seiko S Endo, Aiko A Fukahori, Akira A Shinagawa, Thomas T Fischer, Juergen J Mueller, Wataru W Takasaki
We investigated the impact of glutathione transferases Mu 1 (GSTM1)- and glutathione transferase Theta 1 (GSTT1)-null genotypes on hepatic GST activities in humans and compared the results with those ...Read More
S B SB Lei, R X RX Peng
Subcellular fractions were isolated from Chinese fetal liver at 4-8 months of age for the determination of glutathione S-transferase (GST). Using 1-chloro-2,4-dinitrobenzene (CDNB) as substrate, GST a...Read More
P David Josephy, Meredith Kent, Bengt Mannervik
We have previously expressed hexa-histidine-tagged human glutathione transferase GST T1-1 at very high levels in an Escherichia colilacZ mutagenicity assay strain. Ethylene dibromide (EDB), which is a...Read More
Kristine L Richardson, Gerardo Gold-Bouchot, Daniel Schlenk
Glutathione s-transferases (GST) play a critical role in the detoxification of exogenous and endogenous electrophiles, as well as the products of oxidative stress. As compared to mammals, GST activity...Read More
I Setl?-kov??, C Wiegand
Liver and gills of roach (Rutilus rutilus) and silver carp (Hypophthalmichthys molitrix) were examined for glutathione S-transferases (GSTs) contents and their substrate specificity and capacity to bi...Read More
Kerstin K Broo, Anna-Karin AK Larsson, Per P Jemth, Bengt B Mannervik
The correlation between sequence diversity and enzymatic function was studied in a library of Theta class glutathione transferases (GSTs) obtained by stochastic recombination of fragments of cDNA enco...Read More
P P Jemth, B B Mannervik
Ser(11) in rat glutathione transferase T2-2 is important for stabilization of the reactive enzyme-bound glutathione thiolate in the reaction with 1-menaphthyl sulfate. The S11A mutation increased the ...Read More
P P Jemth, B B Mannervik
The reaction mechanism of rat glutathione transferase T2-2 has been studied using pre-steady-state and steady-state kinetics. Several parts of the catalytic cycle including binding of substrates, prod...Read More