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Porcine serum can be biofortified with selenium to inhibit proliferation of three types of human cancer cells.
Our objectives were to determine if porcine serum could be enriched with selenium (Se) by feeding pigs with high concentrations of dietary Se and if the Se-biofortified serum inhibited proliferation o...Read More
Selenoprotein P (SeP) not only represents the major selenoprotein in plasma, but also provides more than 50% of the total plasma selenium. However, there is no report concerning the direct action of s...Read More
Many patients receiving cancer treatment use micronutrient supplements, with the intention to complement their cancer treatment, or help them cope with the therapy- and disease-associated side-effects...Read More
Relationship between serum levels of testosterone, zinc and selenium in infertile males attending fertility clinic in Nnewi, south east Nigeria.
In the recent years, male infertility and sub-fertility have increased, which is attributable to many factors. Some trace elements such as zinc and selenium have been shown to play a role in reproduct...Read More
Zinc supplementation alters plasma aluminum and selenium status of patients undergoing dialysis: a pilot study.
End stage renal disease patients undergoing long-term dialysis are at risk for abnormal concentrations of certain essential and non-essential trace metals and high oxidative stress. We evaluated the e...Read More
Dietary Advice on Inuit Traditional Food Use Needs to Balance Benefits and Risks of Mercury, Selenium, and n3 Fatty Acids.
Elevated concentrations of mercury (Hg) are commonly found in the traditional foods, including fish and marine mammals, of Inuit living in Canada's Arctic. As a result, Inuit often have higher di...Read More
Profiling the ionome of rice and its use in discriminating geographical origins at the regional scale, China.
Element profile was investigated for their use to trace the geographical origin of rice (Oryza sativa L.) samples. The concentrations of 13 elements (calcium (Ca), potassium (K), magnesium (Mg), phosp...Read More
High prevalence of hyperplastic and autoimmune diseases of thyroid in Ukrainian population is determined by endemic deficit of iodine and selenium. The aim of this research was to assess the place of ...Read More
The effect of different dietary levels of vitamin E and selenium on antioxidant status and immunological markers in serum of laying hens.
The effect of different dietary levels of selenium (Se) and vitamin E on egg production, the antioxidant status and the immune system response of hens was investigated in the current study. A total of...Read More
Prostate cancer is a leading cause of morbidity and mortality in men and has significant treatment-associated complications. Prostate cancer chemoprevention has the potential to decrease the morbidity...Read More
In 2010, in France, 8,790 men died from prostate cancer despite a low and decreasing mortality rate. The individual risk/benefit ratio of prostate cancer screening is the focus of controversy and curr...Read More
The Effect of Selenium Therapy on Mortality in Patients With Sepsis Syndrome: Simple Selenium Supplementation or Real (5 H2O)·Na2SeO3 Pharmacological Effect?*.
Effects of selenium coating of orthopaedic implant surfaces on bacterial adherence and osteoblastic cell growth.
The aim of this study was to evaluate whether coating titanium discs with selenium in the form of sodium selenite decreased bacterial adhesion of Staphylococcus aureus and Staph. epidermidis and imped...Read More
Selenium supranutrition: are the potential benefits of chemoprevention outweighed by the promotion of diabetes and insulin resistance?
Selenium was considered a toxin until 1957, when this mineral was shown to be essential in the prevention of necrotic liver damage in rats. The hypothesis of selenium chemoprevention is principally fo...Read More
The effect of selenium therapy on mortality in patients with sepsis syndrome: a systematic review and meta-analysis of randomized controlled trials.
Patients with sepsis syndrome commonly have low serum selenium levels. Several randomized controlled trials have examined the efficacy of selenium supplementation on mortality in patients with sepsis....Read More
Selenium and prostate cancer prevention: insights from the selenium and vitamin E cancer prevention trial (SELECT).
The Selenium and Vitamin E Cancer Prevention Trial (SELECT) was conducted to assess the efficacy of selenium and vitamin E alone, and in combination, on the incidence of prostate cancer. This randomiz...Read More
To estimate serum zinc and selenium levels in a group of healthy subjects and correlate these with epileptic patients.This case-control study was conducted in the Department of Neurology, Valiasr Hosp...Read More
The effects of selenium (Se) supplementation and source on equine immune function have not been extensively studied. This study examined the effects of oral Se supplementation and Se source on aspects...Read More
Selenium toxicity from a misformulated dietary supplement, adverse health effects, and the temporal response in the nail biologic monitor.
Use of dietary supplements in the U.S. has increased steadily over the last 25 years. While misformulation is uncommon, the consequences can be serious. A March 2008 voluntary market recall removed su...Read More
Nanobiotechnology represents an economic alternative for chemical and physical methods of nanoparticles formation. The objectives of this study were to synthesize selenium nanoparticles by microbial p...Read More
There are pieces of evidence suggesting that oxidative stress and immune responses play significant roles in the etiopathogenesis of some malignant diseases. Also increased oxidative stress in patient...Read More
Selenium status alters the immune response and expulsion of adult Heligmosomoides bakeri worms in mice.
Heligmosomoides bakeri is a nematode with parasitic development exclusively in the small intestine of infected mice that induces a potent STAT6-dependent Th2 immune response. We previously demonstrate...Read More
Influence of inorganic and organic selenium on number of living mycelial cells and their ultrastructure in culture of Hericium erinaceum (Bull.: Fr. Pers.).
Mycelium of the white-rot fungus (Hericium erinaceum (Bull.: Fr. Pers.) produces polysaccharides showing anticancer and immunostimulating activity. In our previous works, we have shown that organic se...Read More
Selenium (Se) is an essential micronutrient that functions as a redox gatekeeper through its incorporation into proteins to alleviate oxidative stress in cells. Although the epidemiological data are s...Read More
Method for the determination of total selenium in a wide variety of foods using inductively coupled plasma/mass spectrometry.
An optimized method for use in a high volume laboratory was developed and validated for the determination of total selenium in a wide variety of food products including infant formula. The method util...Read More
The aim of this study was to present the current state of knowledge of the role of selenium in Graves' disease. Recently, in the pathogenesis and course of this autoimmune disease, more attention...Read More
Measurement of vitamin A, vitamin E, selenium, and L-lactate in dogs with and without osteoarthritis secondary to ruptured cranial cruciate ligament.
This study compared vitamin A, vitamin E, selenium (Se), and L-lactate in blood and synovial fluid in 2 groups of 6 dogs; a control group (without OA) and an osteoarthritic group with spontaneous cran...Read More
Incorporation of selenium into ～25 mammalian selenoproteins occurs by translational recoding whereby in-frame UGA codons are redefined to encode the selenium containing amino acid, selenocysteine (S...Read More