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磺胺熔点标准品

产品编号 S128319 | CAS号 63-74-1 | 阿拉丁
Sulfanilamide Melting Point Standard
+164 to +166℃
组合的产品项目
货号 规格 库存 价格 数量
S128319-1g +164 to +166℃ 上海(9)
北方(预计3-5个工作日)
 
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属性

密度 1.0800
存贮条件 室温储存

描述

别名 磺胺;氨苯磺酰胺;对氨基苯磺酰胺;4-氨基苯磺酰胺;氨苯磺胺;磺酰胺;p-Aminobenzenesulfonamide C-SN
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RTECS WO8400000
WGK德国 3
参考文献
Charles W CW Locuson, Peter M PM Gannett, Robyn R Ayscue, Timothy S TS Tracy
Several laboratories have demonstrated that activation of drug metabolism by P450s may occur via a mechanism that resembles allosterism from an enzyme kinetic standpoint. Because the effector drug bin...Read More
Helen Hurst, Richard H Clothier, Margaret Pratten
The chick micromass culture system has advantages over the validated rat system - ready availability and non-culling of the donor parent - but needs to give comparable results. This study confirmed co...Read More
S Ekins, A J Williams, J J Xu
Drug-induced liver injury (DILI) is one of the most important reasons for drug development failure at both preapproval and postapproval stages. There has been increased interest in developing predicti...Read More
Nigel N Greene, Lilia L Fisk, Russell T RT Naven, Reine R RR Note, Mukesh L ML Patel, Dennis J DJ Pelletier
Drug-induced liver injury is a major issue of concern and has led to the withdrawal of a significant number of marketed drugs. An understanding of structure-activity relationships (SARs) of chemicals ...Read More
Anna A Ohradanova, Daniela D Vullo, Silvia S Pastorekova, Jaromir J Pastorek, Daniel J DJ Jackson, Gert G W?rheide, Claudiu T CT Supuran
The α-carbonic anhydrase (CA, EC 4.2.1.1) Astrosclerin-3 previously isolated from the living fossil sponge Astrosclera willeyana (Jackson et al., Science 2007, 316, 1893), was cloned, kinetically cha...Read More
Anthony Bertucci, Alessio Innocenti, Andrea Scozzafava, Sylvie Tambutté, Didier Zoccola, Claudiu T Supuran
The catalytic activity and the inhibition of a new coral carbonic anhydrase (CA, EC 4.2.1.1), from the scleractinian coral Stylophora pistillata, STPCA-2, has been investigated. STPCA-2 has high catal...Read More
Dheeraj D Mandloi, Sheela S Joshi, Padmakar V PV Khadikar, Navita N Khosla
Sulfa drugs are building blockers of several types of Mannich bases. Consequently, the antibacterial activities of sulfa drugs are reported in this paper, which will help in explaining and understandi...Read More
K K Louati, F F Mistiri, M M Kallel, F F Safta
Sulfadimethoxine was subjected to different International Conference on Harmonisation prescribed stress conditions (hydrolysis, oxidation and photolysis). A stability-indicating high-performance liqui...Read More
Rohan A Davis, Alessio Innocenti, Sally-Ann Poulsen, Claudiu T Supuran
We have investigated the enzyme inhibition characteristics of a natural product (NP)-based phenolic library against a panel of human carbonic anhydrases (hCAs, EC 4.2.1.1) which included hCAs I and II...Read More
Rohan A Davis, Andreas Hofmann, Asiah Osman, Rebecca A Hall, Fritz A Mu?hlschlegel, Daniela Vullo, Alessio Innocenti, Claudiu T Supuran, Sally-Ann Poulsen
In order to discover novel probes that may help in the investigation and control of infectious diseases through a new mechanism of action, we have evaluated a library of phenol-based natural products ...Read More
Alfonso A Pérez-Garrido, Aliuska A Morales Helguera, Adela A Abellán Guillén, M Natália D S MN Cordeiro, Amalio A Garrido Escudero
This paper reports a QSAR study for predicting the complexation of a large and heterogeneous variety of substances (233 organic compounds) with @b-cyclodextrins (@b-CDs). Several different theoretical...Read More
Zhichao Liu, Qiang Shi, Don Ding, Reagan Kelly, Hong Fang, Weida Tong
Drug-induced liver injury (DILI) is a significant concern in drug development due to the poor concordance between preclinical and clinical findings of liver toxicity. We hypothesized that the DILI typ...Read More
Giorgio G Ottaviani, Sophie S Martel, Pierre-Alain PA Carrupt
The development of in silico and in vitro tools to estimate or predict the passive human skin permeation and distribution of new chemical entities, useful in dermal drug delivery, in absorption studie...Read More
Denis Fourches, Julie C Barnes, Nicola C Day, Paul Bradley, Jane Z Reed, Alexander Tropsha
Drug-induced liver injury is one of the main causes of drug attrition. The ability to predict the liver effects of drug candidates from their chemical structures is critical to help guide experimental...Read More
Daniela D Vullo, Juha J Voipio, Alessio A Innocenti, Claudio C Rivera, Harri H Ranki, Andrea A Scozzafava, Kai K Kaila, Claudiu T CT Supuran
The inhibition of a newly cloned human carbonic anhydrase (CA, EC 4.2.1.1), isozyme VII (hCA VII), has been investigated with a series of aromatic and heterocyclic sulfonamides, including some of the ...Read More
Isao Nishimori, Tomoko Minakuchi, Kaori Morimoto, Shuichi Sano, Saburo Onishi, Hiroaki Takeuchi, Daniela Vullo, Andrea Scozzafava, Claudiu T Supuran
We have cloned and sequenced Helicobacter pylori alpha-class carbonic anhydrase (hpCA) from patients with different gastric mucosal lesions, including gastritis (n=15), ulcer (n=6), and cancer (n=16)....Read More
Isao Nishimori, Daniela Vullo, Tomoko Minakuchi, Kaori Morimoto, Saburo Onishi, Andrea Scozzafava, Claudiu T Supuran
A library of sulfonamides/sulfamates has been investigated for the inhibition of the carboxyterminal truncated form of the alpha-carbonic anhydrase (CA, EC 4.2.1.1) isolated from the gastric pathogen ...Read More
Isao I Nishimori, Tomoko T Minakuchi, Saburo S Onishi, Daniela D Vullo, Andrea A Scozzafava, Claudiu T CT Supuran
The secretory isozyme of human carbonic anhydrase (hCA, EC 4.2.1.1), hCA VI, has been cloned, expressed, and purified in a bacterial expression system. The kinetic parameters for the CO2 hydration rea...Read More
Brendan L BL Wilkinson, Laurent F LF Bornaghi, Anthony D AD Wright, Todd A TA Houston, Sally-Ann SA Poulsen
We're sorry this abstract is currently not available....Read More
Isao I Nishimori, Tomoko T Minakuchi, Takuhiro T Kohsaki, Saburo S Onishi, Hiroaki H Takeuchi, Daniela D Vullo, Andrea A Scozzafava, Claudiu T CT Supuran
We're sorry this abstract is currently not available....Read More
Isao I Nishimori, Tomoko T Minakuchi, Saburo S Onishi, Daniela D Vullo, Alessandro A Cecchi, Andrea A Scozzafava, Claudiu T CT Supuran
We're sorry this abstract is currently not available....Read More
Isao Nishimori, Daniela Vullo, Alessio Innocenti, Andrea Scozzafava, Antonio Mastrolorenzo, Claudiu T Supuran
The inhibition of the last human carbonic anhydrase (CA, EC 4.2.1.1) isozyme (hCA XIV) discovered has been investigated with a series of sulfonamides, including some clinically used derivatives (aceta...Read More
Mika Hilvo, Anna Maria Salzano, Alessio Innocenti, Markku S Kulomaa, Andrea Scozzafava, Andrea Scaloni, Seppo Parkkila, Claudiu T Supuran
We have cloned and purified to homogeneity the latest member of the mammalian alpha-carbonic anhydrase (CA, EC 4.2.1.1) family, the mouse CA XV (mCA XV) protein. An investigation on the post-translati...Read More
Fabrizio Carta, Alfonso Maresca, Adrian Suarez Covarrubias, Sherry L Mowbray, T Alwyn Jones, Claudiu T Supuran
The Rv3588c gene product of Mycobacterium tuberculosis, a @b-carbonic anhydrase (CA, EC 4.2.1.1) denominated here mtCA 2, shows the highest catalytic activity for CO"2 hydration (k"c"a&...Read More
Semra Isik, Feray Kockar, Meltem Aydin, Oktay Arslan, Ozen Ozensoy Guler, Alessio Innocenti, Andrea Scozzafava, Claudiu T Supuran
The protein encoded by the Nce103 gene of Saccharomyces cerevisiae, a @b-carbonic anhydrase (CA, EC 4.2.1.1) designated as scCA, has been cloned, purified, characterized kinetically and investigated f...Read More
Alessio Innocenti, Rebecca A Hall, Christine Schlicker, Andrea Scozzafava, Clemens Steegborn, Fritz A Mühlschlegel, Claudiu T Supuran
The @b-carbonic anhydrase (CA, EC 4.2.1.1) from the fungal pathogen Candida albicans (Nce103) is involved in a CO"2 sensing pathway critical for the pathogen life cycle and amenable to drug desig...Read More
Anthony Bertucci, Alessio Innocenti, Didier Zoccola, Andrea Scozzafava, Sylvie Tambutté, Claudiu T Supuran
The inhibition of a newly cloned coral carbonic anhydrase (CA, EC 4.2.1.1) has been investigated with a series of sulfonamides, including some clinically used derivatives (acetazolamide, methazolamide...Read More
Pascale P Joseph, Fran?ois F Turtaut, Safia S Ouahrani-Bettache, Jean-Louis JL Montero, Isao I Nishimori, Tomoko T Minakuchi, Daniela D Vullo, Andrea A Scozzafava, Stephan S K?hler, Jean-Yves JY Winum, Claudiu T CT Supuran
A beta-carbonic anhydrase (CA, EC 4.2.1.1) from the bacterial pathogen Brucella suis, bsCA 1, has been cloned, purified, and characterized kinetically. bsCA 1 has appreciable activity as catalyst for ...Read More
Pascale Joseph, Safia Ouahrani-Bettache, Jean-Louis Montero, Isao Nishimori, Tomoko Minakuchi, Daniela Vullo, Andrea Scozzafava, Jean-Yves Winum, Stephan K?hler, Claudiu T Supuran
A @b-carbonic anhydrase (CA, EC 4.2.1.1) from the bacterial pathogen Brucella suis, bsCA II, has been cloned, purified, and characterized kinetically. bsCA II showed high catalytic activity for the hy...Read More
Isao I Nishimori, Tomoko T Minakuchi, Daniela D Vullo, Andrea A Scozzafava, Claudiu T CT Supuran
The two β-carbonic anhydrases (CAs, EC 4.2.1.1) from the bacterial pathogen Salmonella enterica serovar Typhimurium, stCA 1 and stCA 2, were investigated for their inhibition with a large panel of su...Read More
Jerry J Avorn
We're sorry this abstract is currently not available....Read More
Yan-Yan YY Fu, Cheng-Xiong CX Yang, Xiu-Ping XP Yan
Metal-organic frameworks (MOFs) with open metal sites have great potential for enhancing adsorption separation of the molecules with different polarities. However, the elution and separation of polar ...Read More
Lili L Wang, Jing J Wu, Qin Q Wang, Chonghui C He, Lei L Zhou, Jing J Wang, Qiaosheng Q Pu
A new, rapid, and sensitive method was proposed for the determination of sulfonamide residues in milk and chicken muscle samples by microchip electrophoresis with laser-induced fluorescence detection....Read More
P Hekman, G J Schefferlie
1. A physiologically-based pharmacokinetic model was developed for the purpose of describing the relationship between plasma concentration of drugs and their deposition into eggs. 2. By incorporating ...Read More
Harold H Ellis
Pick up any bound volume of a general medical journal of 1934 (75 years ago - within the memory of old members of the profession), and there are likely to be papers concerning the dreaded effects of t...Read More
I Meneau, D Sanglard, J Bille, P M Hauser
Failure of anti-Pneumocystis jiroveci prophylaxis with sulfa drugs is associated with mutations within the putative active site of the fungal dihydropteroate synthase (DHPS), an enzyme encoded by the ...Read More
Wenfa Lu, Guojian Wei, Wanling Pan, Henry Tabel
Wild-type (WT) C57BL/6 mice infected intraperitoneally with 5 × 10(6) Trypanosoma congolense survive for more than 30 days. C57BL/6 mice deficient in inducible nitric oxide synthase (iNOS(-/-)) and i...Read More
Leila Hajiaghababaei, Babak Ghasemi, Alireza Badiei, Hassan Goldooz, Mohammad Reza Ganjali, Ghodsi Mohammadi Ziarani
A rapid method for the extraction and monitoring of nanogram level of Pb2+ and Cu2+ ions using uniform silanized mesopor (SBA-15) functionalized with aminobenzenesulfonamide groups and flame atomic ab...Read More
Fran?ois F Baert, Julie J Colomb, Thierry T Billard
We're sorry this abstract is currently not available....Read More
Ramazan Demirda?, Veysel Comakl?, Murat Sentürk, Deniz Ekinci, O Irfan Küfrevio?lu, Claudiu T Supuran
Carbonic anhydrase (CA, EC: 4.2.1.1) was purified from sheep kidney by affinity chromatography on a Sepharose 4B-tyrosine-sulfanilamide column. By means of two consecutive procedures, the enzyme (sCA)...Read More
Katja Pajula, Vesa-Pekka Lehto, Jarkko Ketolainen, Ossi Korhonen
The applicability of the computational docking approach was investigated to create a novel method for quick additive screening to inhibit the crystallization taking place in amorphous drugs. Surface e...Read More
Hang H Wang, Ju-fang JF Yan, Xiao-li XL Song, Li L Fan, Jin J Xu, Guang-ming GM Zhou, Li L Jiang, Da-cheng DC Yang
We wish to report the further design and improved synthesis that resulted in two series of target molecules, TM-1 and TM-2, with remarkably simplified structures containing β-amino ketone of discrete...Read More
Reiko R Eyanagi, Akihisa A Toda, Masumi M Imoto, Hidemori H Uchiyama, Yuji Y Ishii, Hiroaki H Kuroki, Yukako Y Kuramoto, Shinji S Soeda, Hiroshi H Shimeno
Drug induced allergies are believed to be induced by conjugates consisting of biological macromolecules and active metabolites. The present study investigated whether guinea pig glutathione S-transfer...Read More
Maria M Boiko, Teodoziya T Vrublevska, Olha O Korkuna, Grigory G Teslyar
A rapid, simple and sensitive spectrophotometric method for the determination of some sulphanilamides is described. The method is based on the formation of blue coloured disazo dyes by the diazotizati...Read More
Sevgi S Kolayli, Fatma F Karahalil, Huseyin H Sahin, Barbaros B Dincer, Claudiu T CT Supuran
An α-carbonic anhydrase (CA, EC 4.2.1.1) was purified and characterized kinetically from erythrocytes of the sturgeon Acipenser gueldenstaedti, an endangered species. The sturgeon enzyme (AgCA) showe...Read More
Xian-Long Wang, Kun Wan, Cheng-He Zhou
A series of novel sulfanilamide-derived 1,2,3-triazole compounds were synthesized in excellent yields via 1,3-dipolar cycloaddition and confirmed by MS, IR and NMR spectra as well as elemental analyse...Read More
Fei F Liu, Agnès A Martin-Mingot, Marie-Paule MP Jouannetaud, Fabien F Zunino, Sébastien S Thibaudeau
The synthesis of benzofused sultams and/or fluorinated sulfonamides, starting from N-allylic sulfonamides, was performed in superacid HF/SbF(5), through superelectrophilic activation. A dramatic effec...Read More
Fabrizio Carta, Blessy Pothen, Alfonso Maresca, Meena Tiwari, Vineet Singh, Claudiu T Supuran
Several substituted benzenesulfonamides were synthesized by various pathways starting from sulfanilamide. The sulfanilamide diazonium salt was reacted with copper (I) halides, potassium iodide and/or ...Read More
Ana Borba, Andrea Gómez-Zavaglia, Rui Fausto
A combined matrix isolation FTIR and theoretical DFT(B3LYP)/6-311++G(3df,3pd) study of sulfanilamide (SA) was performed. The full conformational search on the potential energy surface of the compound ...Read More
Jarinya Sittiwong, Sumonman Niamlang, Nophawan Paradee, Anuvat Sirivat
The controlled release of benzoic acid (3.31??) and sulphanilamide (3.47??) from poly(vinyl alcohol), PVA, hydrogels fabricated by solution casting at various cross-linking ratios, were investigated. ...Read More
Massinissa Si MS Mehand, Gregory G De Crescenzo, Bala B Srinivasan
Surface plasmon resonance-based biosensors are now acknowledged as robust and reliable instruments to determine the kinetic parameters related to the interactions between biomolecules. These kinetic p...Read More
Penghua P Wang, Tao T Zhou, Rong R Wang, Teik-Thye TT Lim
A novel carbon-sensitized and nitrogen-doped TiO2 (C/N-TiO2) was synthesized by a facile sol-gel method using titanium butoxide as both titanium precursor and carbon source, and nitric acid as nitroge...Read More
Robert M Feibel
Trachoma has been one of the most blinding diseases in the history of ophthalmology. From its initial description in antiquity until the late 1930s, no specific treatment or effective cure had been kn...Read More
Da-Cheng DC Yang, Ju-Fang JF Yan, Jin J Xu, Fei F Ye, Zu-Wen ZW Zhou, Wei-Yu WY Zhang, Li L Fan, Xin X Chen
Searching for new antidiabetic lead compound, 4-(1-aryl-3-oxo-5-phenylpentylamino) benzenesulfonamides were designed and synthesized directly by three component one-pot condensation of 4-phenyl-2-buta...Read More
Eduard Sergienko, Ying Su, Xochella Chan, Brock Brown, Andrew Hurder, Sonoko Narisawa, José Luis Millán
Tissue-nonspecific alkaline phosphatase (TNAP) is a ubiquitous enzyme expressed at high levels in bone, liver, and kidney. It appears involved in dephosphorylation of numerous phosphate monoesters, bu...Read More
Alessio A Innocenti, Michael A MA Firnges, Jochen J Antel, Michael M Wurl, Andrea A Scozzafava, Claudiu T CT Supuran
An inhibition study of the human and bovine membrane-associated isozymes of carbonic anhydrase (CA, EC 4.2.1.1), hCA IV and bCA IV, with a series of sulfonamides and sulfamates, some of which are wide...Read More
Sheela S Joshi, Navita N Khosla, Deepak D Khare, Rakesh R Sharda
A series of novel Mannich bases derived from 5-chloro-2-methoxybenzamide and sulfonamides/amines have been synthesised and the antibacterial activities were evaluated against various Gram positive and...Read More
Jean-Yves JY Winum, Alessandro A Cecchi, Jean-Louis JL Montero, Alessio A Innocenti, Andrea A Scozzafava, Claudiu T CT Supuran
A library of boron-containing carbonic anhydrase (CA, EC 4.2.1.1) inhibitors, including sulfonamides, sulfamides, and sulfamates is reported. The new compounds have been synthesized by derivatization ...Read More
Hasan H Turkmen, Mustafa M Durgun, Serpil S Yilmaztekin, Mahmut M Emul, Alessio A Innocenti, Daniela D Vullo, Andrea A Scozzafava, Claudiu T CT Supuran
A series of sulfonamides has been obtained by reacting sulfanilamide or 5-amino-1,3,4-thiadiazole-2-sulfonamide with @w-chloroalkanoyl chlorides, followed by replacement of the @w-chlorine atom with s...Read More
Francesco Mincione, Michele Starnotti, Emanuela Masini, Lucia Bacciottini, Chiara Scrivanti, Angela Casini, Daniela Vullo, Andrea Scozzafava, Claudiu T Supuran
A new series of thioureido-substituted sulfonamides were prepared by reacting 4-isothiocyanato- or 4-isothiocyanatoethyl-benzenesulfonamide with amines, hydrazines, or amino acids bearing moieties tha...Read More
Ozen Ozensoy, Luca Puccetti, Giuseppe Fasolis, Oktay Arslan, Andrea Scozzafava, Claudiu T Supuran
The inhibition of the two transmembrane, tumor-associated isozymes of carbonic anhydrase (CA, EC 4.2.1.1) of human origin, hCA IX and XII, with a library of aromatic and heteroaromatic sulfonamides ha...Read More
Padmakar V PV Khadikar, Vimukta V Sharma, Sneha S Karmarkar, Claudiu T CT Supuran
A novel use of NMR chemical shift of the SO"2NH"2 protons (in dioxane as solvent) as a molecular descriptor is described for modeling the inhibition constant for benzene sulfonamides against...Read More
Vijay K Agrawal, Jyoti Singh, Padmakar V Khadikar, Claudiu T Supuran
A quantitative Structure-activity relationship study (QSAR) on a set of carbonic anhydrase (CA, EC 4.2.1.1) inhibitors is reported using first-order valence connectivity index ((1)chi(v)). The inhibit...Read More
Ahmed A Kamal, M Naseer A MN Khan, K Srinivasa KS Reddy, K K Rohini, G Narahari GN Sastry, B B Sateesh, B B Sridhar
We're sorry this abstract is currently not available....Read More
Ahmed A Kamal, M Naseer A MN Khan, K K Srinivasa Reddy, K K Rohini
Synthesis and evaluation of N'-1-[2-anilino-3-pyridyl]carbonyl 1-benzenesulfonohydrazide derivatives (7a-i) as anticancer and antibacterial agents....Read More
Marouan Rami, Jean-Yves Winum, Alessio Innocenti, Jean-Louis Montero, Andrea Scozzafava, Claudiu T Supuran
We're sorry this abstract is currently not available....Read More
Claudia Temperini, Alessio Innocenti, Andrea Scozzafava, Seppo Parkkila, Claudiu T Supuran
Coumarins constitute a general and totally new class of inhibitors of the zinc enzyme carbonic anhydrase (CA, EC 4.2.1.1), binding at the entrance of the active site cavity. We report here that the co...Read More
Daniela Vullo, Isao Nishimori, Andrea Scozzafava, Stephan K?hler, Jean-Yves Winum, Claudiu T Supuran
A beta-carbonic anhydrase (CA, EC 4.2.1.1) from the bacterial pathogen Brucella suis, bsCA 1, has been cloned, purified characterized kinetically and for inhibition with a series of water soluble glyc...Read More
Kalyan K Sethi, Saurabh M Verma, Naru Prasanthi, Suvendu K Sahoo, Rabi N Parhi, P Suresh
Three-dimensional quantitative structure-activity relationship (3D-QSAR) studies were performed for a series of carbonic anhydrase inhibitors using comparative molecular field analysis (CoMFA) and com...Read More
Feray Kockar, Alfonso Maresca, Meltem Aydin, Semra I?ik, Sumeyye Turkoglu, Selma Sinan, Oktay Arslan, Ozen Ozensoy Güler, Yusuf Turan, Claudiu T Supuran
Site-directed mutagenesis has been used to change one amino acid residue considered non essential (Phe91Asn) to catalysis in carbonic anhydrase (CA, EC 4.2.1.1) isozyme I (hCA I), but which is near th...Read More
Fabio Pacchiano, Fabrizio Carta, Daniela Vullo, Andrea Scozzafava, Claudiu T Supuran
A series of sulfonamides was prepared by reaction of sulfanilamide with aryl/alkyl isocyanates. The ureido-substituted benzenesulfonamides showed a very interesting profile for the inhibition of sever...Read More
Yohei Munei, Kazunori Shimamoto, Masataka Harada, Tatsusada Yoshida, Hiroshi Chuman
We proposed a novel QSAR (quantitative structure-activity relationship) procedure called LERE (linear expression by representative energy terms)-QSAR involving molecular calculations such as ab initio...Read More
Marouan M Rami, Alfonso A Maresca, Fatma-Zhora FZ Smaine, Jean-Louis JL Montero, Andrea A Scozzafava, Jean-Yves JY Winum, Claudiu T CT Supuran
A new series of sulfonamides was synthesized by the reaction of the boroxazolidone complex of l-lysine with isothiocyanates incorporating sulfamoyl moieties and diverse organic scaffolds. The obtained...Read More
Edward E EE Knaus, Alessio A Innocenti, Andrea A Scozzafava, Claudiu T CT Supuran
A series of compounds incorporating regioisomeric phenylethynylbenzenesulfonamide moieties has been investigated for the inhibition of four human carbonic anhydrase (hCA, EC 4.2.1.1) isoforms, hCA I, ...Read More
Sumeyye S Turkoglu, Alfonso A Maresca, Meltem M Alper, Feray F Kockar, Semra S I??k, Selma S Sinan, Ozen O Ozensoy, Oktay O Arslan, Claudiu T CT Supuran
Site-directed mutagenesis has been used to change three amino acid residues involved in the binding of inhibitors (Asn67Ile; Gln92Val and Leu204Ser) within the active site of human carbonic anhydrase ...Read More
Janina J Moeker, Kanae K Teruya, Sabine S Rossit, Brendan L BL Wilkinson, Marie M Lopez, Laurent F LF Bornaghi, Alessio A Innocenti, Claudiu T CT Supuran, Sally-Ann SA Poulsen
A library of 32 novel glycoconjugate thiourea-bridged benzene sulfonamides have been synthesized from the reaction of glycosyl isothiocyanates with a panel of simple benzene sulfonamides comprising ei...Read More

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