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水杨酸熔点标准品

产品编号 S128322 | CAS号 69-72-7 | 阿拉丁
Salicylic acid Melting Point Standard
+158 to +160℃
组合的产品项目
货号 规格 库存 价格 数量
S128322-1g +158 to +160℃ 上海(预计3-7周)
北方(>10)
 
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属性

敏感性 对光敏感
溶解性 Soluble in water (1.8 g/L),

描述

产品介绍 Salicylic acid is a natural product extract from Willow bark, well known as an antiinflammatory and antinociceptive agent and a close structural relative to acetylsalicylic acid (aspirin). Salicylic acid is a ubiquitous plant hormone with many regulatory functions involved in local disease resistance mechanisms and systemic acquired resistance. The antiinflammatory and antinociceptive effects produced by Salicylic acid and its derivatives in animals are due to inhibition of COX-1 and COX-2 (cyclooxygenase) enzyme activity and suppression of prostaglandin biosynthesis. Salicylic acid is also of interest as a starting material for the organic synthesis of more elaborate COX suppressors and other chemical structures.
别名 柳酸; 沙利西酸; 撒酸; 邻羟基苯甲酸; 2-羟基苯甲酸;2-Hydroxybenzoic acid; Bis(2-hydroxyethyl)iminotris(hydroxymethyl)methane
应用 测定铝、硼、铈、铜、铁、铅、锰、汞、银、钛、钨、钒、次亚硫酸盐,硝酸盐和亚硝酸盐。沉淀钍使钍从铈及其他稀土元素中分离出来,分离锆与钛。荧光指示剂;防腐剂;络合指示剂。
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标识符号 GHS05 GHS05, GHS07 GHS07
信号词 Danger
风险声明 (欧洲) R22;R36/37/38;R41
安全声明(欧洲) S26;S37/39
警示性声明 P280,P305+P351+P338
危害码(欧洲) Xn
危害声明 H302,H318
RTECS VO0525000
WGK德国 1
参考文献
A Guerra, N E Campillo, J A Páez
A neural model based on a numerical molecular representation using CODES program to predict oral absorption of any structure is described. This model predicts both high and low-absorbed compounds with...Read More
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F M Shakirova, M V Bezrukova, R A Yuldashev, R A Fatkhutdinova, A R Murzabaev
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Jihye J Kim, Sookjin S Kang, Sungchae S Hong, Soowhan S Yum, Young Mi YM Kim, Yunjin Y Jung
To develop a more potent NFκB inhibitor from salicylic acid which is known to inhibit activity of NFκB, a transcription factor regulating genes involved in immunity, inflammation and tumorigenesis, ...Read More
Wendy R Russell, Lorraine Scobbie, Garry G Duthie, Andrew Chesson
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Lei Du-Cuny, Zuohe Song, Sylvestor Moses, Garth Powis, Eugene A Mash, Emmanuelle J Meuillet, Shuxing Zhang
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Michael H Abraham, Adam Ibrahim, William E Acree
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In the light of known HDAC inhibitors, 33 carboxylic acid derivatives were tested to understand the structural requirements for HDAC inhibition activity. Several modifications were applied to develop ...Read More
Giorgio G Ottaviani, Sophie S Martel, Pierre-Alain PA Carrupt
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Denis Fourches, Julie C Barnes, Nicola C Day, Paul Bradley, Jane Z Reed, Alexander Tropsha
Drug-induced liver injury is one of the main causes of drug attrition. The ability to predict the liver effects of drug candidates from their chemical structures is critical to help guide experimental...Read More
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Wolfram W Gronwald, Matthias S MS Klein, Raoul R Zeltner, Bernd-Detlef BD Schulze, Stephan W SW Reinhold, Markus M Deutschmann, Ann-Kathrin AK Immervoll, Carsten A CA B?ger, Bernhard B Banas, Kai-Uwe KU Eckardt, Peter J PJ Oefner
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David D Buttar, Nicola N Colclough, Stefan S Gerhardt, Philip A PA MacFaul, Scott D SD Phillips, Alleyn A Plowright, Paul P Whittamore, Kin K Tam, Klaus K Maskos, Stefan S Steinbacher, Holger H Steuber
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Loretta L Lazzarato, Monica M Donnola, Barbara B Rolando, Elisabetta E Marini, Clara C Cena, Gabriella G Coruzzi, Elena E Guaita, Giuseppina G Morini, Roberta R Fruttero, Alberto A Gasco, Stefano S Biondi, Ennio E Ongini
A new class of products in which the phenol group of salicylic acid is linked to alkanoyl moieties bearing nitrooxy functions has been synthesized and studied for their polyvalent actions. The product...Read More
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Esra Bayram, Murat Senturk, O Irfan Kufrevioglu, Claudiu T Supuran
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M M Rutner, J J Fitzek, H H Jahnel-Kracht, J J Otto, W W Krause
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Loretta L Lazzarato, Clara C Cena, Barbara B Rolando, Elisabetta E Marini, Marco Lucio ML Lolli, Stefano S Guglielmo, Elena E Guaita, Giuseppina G Morini, Gabriella G Coruzzi, Roberta R Fruttero, Alberto A Gasco
A new group of derivatives of salicylic acid containing NO-donor furoxans, and the related des-NO-furazans, were synthesized and evaluated as new aspirin-like molecules. Their stability was assessed i...Read More
Thorsten E TE Fisher, Boyoung B Kim, Donnette D DD Staas, Terry A TA Lyle, Steven D SD Young, Joseph P JP Vacca, Matthew M MM Zrada, Daria J DJ Hazuda, Peter J PJ Felock, William A WA Schleif, Lori J LJ Gabryelski, M Reza MR Anari, Christopher J CJ Kochan
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Melinda Roberts, Saijun Tang, Anna Stallmann, Jeffery L Dangl, Vera Bonardi
Plants react to pathogen attack via recognition of, and response to, pathogen-specific molecules at the cell surface and inside the cell. Pathogen effectors (virulence factors) are monitored by intrac...Read More
Maren Friebe, Stephan Schumacher, Jessica Stahl, Manfred Kietzmann
This study investigated synovial concentrations of acetylsalicylic acid (ASA) and its metabolite salicylic acid (SA) in the equine fetlock joint following systemic administration of ASA. Salicylates w...Read More
Liyu Shi, Jianfeng Weng, Changlin Liu, Xinyuan Song, Hongqin Miao, Zhuanfang Hao, Chuanxiao Xie, Mingshun Li, Degui Zhang, Li Bai, Guangtang Pan, Xinhai Li, Shihuang Zhang
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Water-deficiency adversely affects crop growth by generating reactive oxygen species (ROS) at cellular level. To mitigate such stressful events, it was aimed to investigate the co-synergism of exogeno...Read More
Ronald L Moy, Corey Levenson, Jeffrey J So, James A Rock
A proprietary topical blend of salicylic acid and highly purified sandalwood oil from Australia was used in this open-label study in adolescents and adults with mild to moderate facial acne.The invest...Read More
Alan R Shalita, Whitney P Bowe
We're sorry this abstract is currently not available....Read More
Lawrence Green, Leon H Kircik, Jennifer Gwazdauskas
Acne vulgaris is a common dermatologic disease that most frequently affects adolescents and young adults. Over-the-counter (OTC) acne treatment regimens are increasingly being used by individuals with...Read More
Ramesh Kekuda, Palanikumar Manoharan, Walter Baseler, Uma Sundaram
Short chain fatty acids (SCFA) are absorbed by carrier mediated uptake in the small intestine by pH-dependent SCFA/HCO3 (-) exchangers on the apical membrane of epithelial cells. Conventional assumpti...Read More
Hongying Cui, Yucheng Sun, Jianwei Su, Chuanyou Li, Feng Ge
The effect of previous infestation (preconditioning) by the whitefly Bemisia tabaci (Gennadius) biotype B on the population fitness of subsequent infestations that fed on three isogenic tomato genotyp...Read More
Clare L Casteel, Lauren M Segal, Olivia K Niziolek, May R Berenbaum, Evan H Delucia
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Limor Poraty-Gavra, Philip Zimmermann, Sabine Haigis, Pawel Bednarek, Ora Hazak, Oksana Rogovoy Stelmakh, Einat Sadot, Paul Schulze-Lefert, Wilhelm Gruissem, Shaul Yalovsky
How plants coordinate developmental processes and environmental stress responses is a pressing question. Here, we show that Arabidopsis (Arabidopsis thaliana) Rho of Plants6 (AtROP6) integrates develo...Read More
Yunlong Du, Ricardo Tejos, Martina Beck, Ellie Himschoot, Hongjiang Li, Silke Robatzek, Steffen Vanneste, Jirí Friml
Removal of cargos from the cell surface via endocytosis is an efficient mechanism to regulate activities of plasma membrane (PM)-resident proteins, such as receptors or transporters. Salicylic acid (S...Read More
Shifeng Cao, Ting Liu, Yueming Jiang, Shenggen He, Dion K Harrison, Daryl C Joyce
The effect of elicitors associated with host defence on betacyanin accumulation in Amaranthus mangostanus seedlings was investigated. Under the conditions of the experiments, betacyanin accumulation w...Read More
Sreeman K Mamidyala, Soumya Ramu, Johnny X Huang, Avril A B Robertson, Matthew A Cooper
Anacardic acid derivatives exhibit a broad range of biological activities. In this report, an efficient method for the synthesis of anacardic acid derivatives was explored, and a small set of salicyli...Read More
Zheng Qing Fu, Xinnian Dong
Systemic acquired resistance (SAR) is an induced immune mechanism in plants. Unlike vertebrate adaptive immunity, SAR is broad spectrum, with no specificity to the initial infection. An avirulent path...Read More
Dorothea Ellinger, Marcel Naumann, Christian Falter, Claudia Zwikowics, Torsten Jamrow, Chithra Manisseri, Shauna C Somerville, Christian A Voigt
A common response by plants to fungal attack is deposition of callose, a (1,3)-β-glucan polymer, in the form of cell wall thickenings called papillae, at site of wall penetration. While it has been g...Read More
Leon H Kircik, Jennifer Gwazdauskas, Victoria Butners, Joseph Eastern, Lawrence J Green
Benzoyl peroxide (BPO) is a widely used over-the-counter (OTC) topical acne treatment often used in combination with salicylic acid (SA) to achieve better comedone control than that achieved with BPO ...Read More
Jinyoung Kwak, Sang-Yup Lee
Photoluminescent spherical nanostructures were prepared through the self-assembly of a tyrosine-containing bolaamphiphilic molecule, and their antenna effect was examined. The photoluminescent spheric...Read More
G Wolf
We're sorry this abstract is currently not available....Read More
Yuhong Li, Weidong Gao, Kongshuang Zhao, Gang Yang, Zhonghe Zhu, Rongjing Cui
The adsorption process of salicylic acid (SA) onto chitosan membrane is monitored in real time by the dielectric relaxation spectroscopy (DRS) method. A unique dielectric relaxation, which is related ...Read More
M M MM Vila, M M Tubino, G G de Oliveira Neto
A flow injection (FI) enzymatic system, based on the use of immobilized salicylate hydroxylase in glass beads, was developed for the determination of salicylate. Salicylate hydroxylase and nicotinamid...Read More
E Hazouard, M Grimbert, A P Jonville-Berra, M C De Toffol, A Legras
We report a case of salicylism caused by association of acetylsalicylic acid (ASA) and acetazolamide. A 50-year-old woman without chronic renal insufficiency, was admitted for confusion, cerebellar at...Read More
P P Singh, M M Anliker, G A GA Smith, D D Zavortink, H I HI Maibach
The potential of transdermal iontophoresis to facilitate drug delivery was evaluated by studying the transport kinetics of model compounds salicylate (anion), phenylethylamine (cation), mannitol (pola...Read More
S G SG Owen, H W HW Francis, M S MS Roberts
1. Five rheumatoid patients with a knee joint effusion participated in the study. An aqueous solution (0.1 to 0.2 ml) containing paracetamol, salicylate, diclofenac and [125I]-albumin was injected int...Read More
A A Kunkel, H H W?tzig
Capillary electrophoresis (CE) is often regarded as a separation technique of choice because of its high selectivity and its cost advantages compared to LC.RSD% of 0.5% have become standard for qualit...Read More
A Quaranta, P Portalatini, M Camporeale, V Sallustio
The aim of this study was to evaluate, in young volunteer subjects, the effects of salicylates on evoked otoacoustic emissions (EOAEs), which presumably reflect an active mechanical process in the coc...Read More
E Benfeldt, J Serup, T Menn??
Our aim was to simultaneously investigate 2 techniques for in vivo sampling of peripheral compartment pharmacokinetics after systemic administration of acetylsalicylic acid. Ten volunteers were given ...Read More
Azaroual, M M Imbenotte, B B Cartigny, M M Lhermitte, G G Vermeersch
By comparison of urine 1H NMR spectrum from a healthy person with those from poisoned patient, we have displayed one or several signals related to intoxication. In complement, various 1H and 13C NMR s...Read More
S Zaugg, X Zhang, J Sweedler, W Thormann
Acetylsalicylic acid (Aspirin) is rapidly metabolized to salicylic acid (salicylate) and other compounds, including gentisic acid and salicyluric acid. Monitoring of salicylate and its metabolites is ...Read More
K K Alanko, S S Stubb, O P OP Salo, S S Reitamo
The histamine concentration was measured from suction blister fluid obtained from normal and lesional skin of 8 patients with fixed drug eruption (FDE) caused by phenazone salicylate and from that of ...Read More
A Z AZ Khan, L L Aarons
A sequential approach is presented to the problem of determining the minimum number of blood samples needed to calculate the plasma to saliva concentration ratio to a required precision. The method wa...Read More
O S Goussis, T J Theodoropoulos
Earlier studies have shown that drugs such as dilantin inhibit T4 binding by thyroid hormone binding globulin (TBG) and cause a displacement of T4 from TBG to prealbumin with no change in the albumin-...Read More
S A SA Kocoshis, C T CT Wong
Previous studies by us suggested that luminally administered sodium salicylate blocks dihydroxy-bile acid-induced colonic secretion in the rat. In the present study, an in vivo rat cecal loop techniqu...Read More
Themba T TT Ndovi, Leena L Choi, Brian B Caffo, Teresa T Parsons, Sharon S Baker, Ming M Zhao, Charles C Rohde, Craig W CW Hendrix
Background: The male genital tract is a complex collection of anatomically and biochemically distinct compartments that contribute to the ejaculate. Understanding the pharmacokinetics in these compart...Read More
J E JE Baggott, S L SL Morgan, T T Ha, W H WH Vaughn, R J RJ Hine
Many non-steroidal anti-inflammatory drugs (NSAIDs) (including sulphasalazine, sulindac, indomethacin, naproxen, salicylic acid, ibuprofen, piroxicam and mefenamic acid) were found to be competitive i...Read More
F P Schmook, J G Meingassner, A Billich
For the study of in-vitro skin penetration of candidate drugs, excised animal skin is frequently used as a replacement for human skin. Reconstructed human skin or epidermis equivalents have been propo...Read More
Anil A Kumar, Balasubramanian B Narasimhan, Devinder D Kumar
We're sorry this abstract is currently not available....Read More
Joshua S Mylne, Conan K Wang, Nicole L van der Weerden, David J Craik
Cyclotides are small cysteine-rich plant peptides similar in size and processing to the defensins. Long-term growth of the Rubiaceae family plant Oldenlandia affinis under different conditions reveals...Read More

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