| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| A114343-1g |
1g |
现货  |
|
| 别名 | 丙硫咪唑 |
|---|---|
| 英文别名 | DTXCID202563 | HMS1568B16 | HMS1922K04 | Zenteltrade mark | Albendazole (USAN:USP:INN:BAN:JAN) | HSDB 7444 | methoxy-N-(5-propylthiobenzimidazol-2-yl)carboxamide | ALBENDAZOLE (EP MONOGRAPH) | ALBENDAZOLE (MART.) | Albendazole [USAN:USP:INN:BAN:JAN] | Opr |
| 规格或纯度 | 分析标准品, ≥99% |
| 英文名称 | Albendazole |
| 生化机理 | 驱虫剂苯并咪唑和微管解聚剂。能够在体外抑制脑微管聚合，并延迟体内微管组装。在体内观察到抗肿瘤活性。 |
| 运输条件 | 常规运输 |
| 作用类型 | 抑制剂 |
| 作用机制 | 微管蛋白抑制剂 |
| 备注 | 如果有可能，您尽量在使用的当天配置溶液，并在当天使用完它。但是，如果您需要预先配制储备溶液，我们建议您将溶液等份保存在-20°C的密封小瓶中。通常，它们最多可以使用一个月。在使用前和打开样品瓶之前，我们建议您让您的产品在室温下平衡至少1小时。有毒，请参阅SDS以获取更多信息。需要更多关于溶解度，用法和处理的建议吗？请访问我们的常见问题（FAQ）页面以获取更多详细信息。 |
| 产品介绍 |
微溶于有机溶剂，不溶于水。无臭。 该品对牛、羊肝片吸虫成虫和幼虫，大片吸虫均有效，减虫率可达90-100%，今年来，发现该品对牛囊尾蚴亦有很强的作用。此外，改频还可用于预防寄生虫的感染，因此对于促进绵羊的生长增加羊毛产量，均可收到较好的效果。 |
| ALogP | 2.9 |
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| 作用机制 | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | 参考文献 |
|---|
| EC号 | 259-414-7 |
|---|---|
| 分子类型 | 小分子 |
| IUPAC Name | methyl N-(6-propylsulfanyl-1H-benzimidazol-2-yl)carbamate |
| INCHI | InChI=1S/C12H15N3O2S/c1-3-6-18-8-4-5-9-10(7-8)14-11(13-9)15-12(16)17-2/h4-5,7H,3,6H2,1-2H3,(H2,13,14,15,16) |
| InChi Key | HXHWSAZORRCQMX-UHFFFAOYSA-N |
| Canonical SMILES | CCCSC1=CC2=C(C=C1)N=C(N2)NC(=O)OC |
| Isomeric SMILES | CCCSC1=CC2=C(C=C1)N=C(N2)NC(=O)OC |
| WGK Germany | 2 |
| RTECS | FD1100000 |
| 分子量 | 265.33 |
| Reaxy-Rn | 4193299 |
| Reaxys-RN link address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=4193299&ln= |
| 溶解性 | 在丙酮或氯仿中微溶，不溶于水，微溶于热稀盐酸，可溶于甲醇、乙醇、乙酸等。 |
|---|---|
| 密度 | 1.3 |
| 熔点 | 208-210°C |
| 分子量 | 265.330 g/mol |
| XLogP3 | 2.900 |
| 氢键供体数Hydrogen Bond Donor Count | 2 |
| 氢键受体数Hydrogen Bond Acceptor Count | 4 |
| 可旋转键计数Rotatable Bond Count | 5 |
| 精确质量Exact Mass | 265.088 Da |
| 单同位素质量Monoisotopic Mass | 265.088 Da |
| 拓扑极表面积Topological Polar Surface Area | 92.300 Ų |
| 重原子数Heavy Atom Count | 18 |
| 形式电荷Formal Charge | 0 |
| 复杂度Complexity | 290.000 |
| 同位素原子数Isotope Atom Count | 0 |
| 定义的原子立体中心计数Defined Atom Stereocenter Count | 0 |
| 未定义的原子立体中心计数Undefined Atom Stereocenter Count | 0 |
| 定义的键立体中心计数Defined Bond Stereocenter Count | 0 |
| 未定义的键立体中心计数Undefined Bond Stereocenter Count | 0 |
| 所有立体化学键的总数The total count of all stereochemical bonds | 0 |
| 共价键合单元计数Covalently-Bonded Unit Count | 1 |
| 象形图 | GHS08, GHS07 |
|---|---|
| 信号词 | Danger |
| 危险声明 |
H315: 引起皮肤刺激 H319: 引起严重眼睛刺激 H335: 可能引起呼吸道刺激 H373: 通过长时间或反复暴露对器官造成损害 H360: 可能损害生育力或未出生的孩子 H361: 怀疑破坏生育力或未出生的孩子 |
| 预防措施声明 |
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P302+P352: 如皮肤沾染：用水充分清洗。 P321: 特殊处理（请参阅此标签上的...）。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P260: 不要吸入灰尘/烟雾/气体/雾/蒸汽/喷雾。 P271: 仅在室外或通风良好的地方使用。 P304+P340: 如误吸入：将人转移到空气新鲜处，保持呼吸舒适体位。 P403+P233: 存放在通风良好的地方。保持容器密闭。 P362+P364: 脱掉沾污的衣服，清洗后方可重新使用。 P203: 使用前，获取、阅读并遵守所有安全说明。 P264+P265: 处理后彻底洗手[和…]。不要触摸眼睛。 P318: 如果暴露或担心，请就医。 P337+P317: 如果眼睛刺激持续：寻求医疗帮助。 P332+P317: 如果出现皮肤刺激：请寻求医疗帮助。 P319: 如果你感到不适，请寻求医疗帮助。 |
| WGK Germany | 2 |
| RTECS | FD1100000 |
| Reaxy-Rn | 4193299 |
| Reaxys-RN link address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=4193299&ln= |
| Merck Index | 210 |
| 个人防护装备 | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
| Nitrogen by Elemental Analysis | 15.3-16.2（%） |
|---|---|
| Purity(Titration by HClO4) | 99-102（%） |
| Purity(HPLC) | 99-100（%） |
| Carbon by Elemental Analysis | 53.2-54.7（%） |
| Appearance（A114343) | White to Yellow Powder |
| Proton NMR spectrum | Conforms to Structure |
| Solubility in DMSO，Faint Yellow to Yellow-Tan ;Clear ;25 mg/mL | Conforms |
通过匹配包装上的批号来查找并下载产品的 COA，每批产品都进行了严格的验证，您可放心使用！
| 批号(Lot Number) | 证书类型 | 日期 | 货号 |
|---|---|---|---|
 L1920091 |
分析证书 | 23-07-17 | A114343 |
| 1. Zhiwei Zhou, Yaohua Yan, Xing Li, Fanxi Zeng, Senlin Shao. (2023) Effect of urea-based chemical cleaning on TrOCs rejection by nanofiltration membranes. SEPARATION AND PURIFICATION TECHNOLOGY, 315 (123662). [10.1016/j.seppur.2023.123662] |
| 2. Yiting Wen, Yujia Zhang, Xiaoli Zhang, Linjun Wang, Qiuxia Pan, Qiuhan Bai, Du Zhu, Weiming Chai. (2023) Inhibition of albendazole and 2-(2-aminophenyl)-1H-benzimidazole against tyrosinase: mechanism, structure–activity relationship, and anti-browning effect. JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE, 103 (6): (2824-2837). [PMID:36641547] [10.1002/jsfa.12450] |
| 3. Tianfeng Yang, Cheng Cheng, Rui Xu, Jian Huo, Xiujuan Peng, Yanbin Chen, Yonghong Liang, Zhiheng Su, Yanmin Zhang. (2022) Albendazole exerts an anti-hepatocellular carcinoma effect through a WWOX-dependent pathway. LIFE SCIENCES, 310 (121086). [PMID:36257459] [10.1016/j.lfs.2022.121086] |
| 4. Yaowei Guo, Jin Liu, Qinglin Tang, Cuicui Li, Yanying Zhang, Yao Wang, Yanxin Wang, Yupeng Bi, Christopher D. Snow, Matt J. Kipper, Laurence A. Belfiore, Jianguo Tang. (2022) Lanthanide (Eu3+/Tb3+)-Loaded γ-Cyclodextrin Nano-Aggregates for Smart Sensing of the Anticancer Drug Irinotecan. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 23 (12): (6597). [PMID:35743042] [10.3390/ijms23126597] |
| 5. Lei Men, Yuhan Zhang, Keke Li, Zhongyu Li, Chunbin Li, Xueyuan Zhang, Xiaojie Gong, Linlin Fang. (2022) Metabolism and pharmacokinetics of mebendazole in Japanese pufferfish (Takifugu rubripes). Food Additives and Contaminants Part A-Chemistry Analysis Control Exposure & Risk Assessment, [PMID:35442868] [10.1080/19440049.2022.2052974] |
| 6. Jingfeng Li, Zhaoyi An, Junyang Sun, Chunyan Tan, Dan Gao, Ying Tan, Yuyang Jiang. (2020) Highly Selective Oxidation of Organic Sulfides by a Conjugated Polymer as the Photosensitizer for Singlet Oxygen Generation. ACS Applied Materials & Interfaces, 12 (31): (35475–35481). [PMID:32658457] [10.1021/acsami.0c10162] |
| 7. Dongze Wang, Gang Chen, Xuemei Li, Qiong Jia. (2019) Hypercrosslinked β-cyclodextrin porous polymer as adsorbent for effective uptake towards albendazole from aqueous media. SEPARATION AND PURIFICATION TECHNOLOGY, 227 (115720). [10.1016/j.seppur.2019.115720] |
| 8. Dongze Wang, Xuemei Li, Xiangqun Jin, Qiong Jia. (2019) Design of cucurbit[6]uril-based hypercrosslinked polymers for efficient capture of albendazole. SEPARATION AND PURIFICATION TECHNOLOGY, 216 (9). [10.1016/j.seppur.2019.01.065] |
| 9. Qin Li, Xuanping Tan, Lingli Fu, Qu Liu, Weiwei Tang. (2015) A novel fluorescence and resonance Rayleigh scattering probe based on quantum dots for the detection of albendazole. Analytical Methods, 7 (2): (614-620). [10.1039/C4AY02289K] |
| 10. Lan Sumin, Chen Kexi, Feng Liqiang, Sima Panle, Ji Xiaoyao, Wu Feihua, Lin Yining. (2025) Tea Saponins: a Novel Stabilizer for Enhancing the Oral Bioavailability of Albendazole Nanocrystals. AAPS PHARMSCITECH, 26 (1): (1-13). [PMID:39779633] [10.1208/s12249-024-03015-1] |
| 1. Zhiwei Zhou, Yaohua Yan, Xing Li, Fanxi Zeng, Senlin Shao. (2023) Effect of urea-based chemical cleaning on TrOCs rejection by nanofiltration membranes. SEPARATION AND PURIFICATION TECHNOLOGY, 315 (123662). [10.1016/j.seppur.2023.123662] |
| 2. Yiting Wen, Yujia Zhang, Xiaoli Zhang, Linjun Wang, Qiuxia Pan, Qiuhan Bai, Du Zhu, Weiming Chai. (2023) Inhibition of albendazole and 2-(2-aminophenyl)-1H-benzimidazole against tyrosinase: mechanism, structure–activity relationship, and anti-browning effect. JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE, 103 (6): (2824-2837). [PMID:36641547] [10.1002/jsfa.12450] |
| 3. Tianfeng Yang, Cheng Cheng, Rui Xu, Jian Huo, Xiujuan Peng, Yanbin Chen, Yonghong Liang, Zhiheng Su, Yanmin Zhang. (2022) Albendazole exerts an anti-hepatocellular carcinoma effect through a WWOX-dependent pathway. LIFE SCIENCES, 310 (121086). [PMID:36257459] [10.1016/j.lfs.2022.121086] |
| 4. Yaowei Guo, Jin Liu, Qinglin Tang, Cuicui Li, Yanying Zhang, Yao Wang, Yanxin Wang, Yupeng Bi, Christopher D. Snow, Matt J. Kipper, Laurence A. Belfiore, Jianguo Tang. (2022) Lanthanide (Eu3+/Tb3+)-Loaded γ-Cyclodextrin Nano-Aggregates for Smart Sensing of the Anticancer Drug Irinotecan. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 23 (12): (6597). [PMID:35743042] [10.3390/ijms23126597] |
| 5. Lei Men, Yuhan Zhang, Keke Li, Zhongyu Li, Chunbin Li, Xueyuan Zhang, Xiaojie Gong, Linlin Fang. (2022) Metabolism and pharmacokinetics of mebendazole in Japanese pufferfish (Takifugu rubripes). Food Additives and Contaminants Part A-Chemistry Analysis Control Exposure & Risk Assessment, [PMID:35442868] [10.1080/19440049.2022.2052974] |
| 6. Jingfeng Li, Zhaoyi An, Junyang Sun, Chunyan Tan, Dan Gao, Ying Tan, Yuyang Jiang. (2020) Highly Selective Oxidation of Organic Sulfides by a Conjugated Polymer as the Photosensitizer for Singlet Oxygen Generation. ACS Applied Materials & Interfaces, 12 (31): (35475–35481). [PMID:32658457] [10.1021/acsami.0c10162] |
| 7. Dongze Wang, Gang Chen, Xuemei Li, Qiong Jia. (2019) Hypercrosslinked β-cyclodextrin porous polymer as adsorbent for effective uptake towards albendazole from aqueous media. SEPARATION AND PURIFICATION TECHNOLOGY, 227 (115720). [10.1016/j.seppur.2019.115720] |
| 8. Dongze Wang, Xuemei Li, Xiangqun Jin, Qiong Jia. (2019) Design of cucurbit[6]uril-based hypercrosslinked polymers for efficient capture of albendazole. SEPARATION AND PURIFICATION TECHNOLOGY, 216 (9). [10.1016/j.seppur.2019.01.065] |
| 9. Qin Li, Xuanping Tan, Lingli Fu, Qu Liu, Weiwei Tang. (2015) A novel fluorescence and resonance Rayleigh scattering probe based on quantum dots for the detection of albendazole. Analytical Methods, 7 (2): (614-620). [10.1039/C4AY02289K] |
| 10. Lan Sumin, Chen Kexi, Feng Liqiang, Sima Panle, Ji Xiaoyao, Wu Feihua, Lin Yining. (2025) Tea Saponins: a Novel Stabilizer for Enhancing the Oral Bioavailability of Albendazole Nanocrystals. AAPS PHARMSCITECH, 26 (1): (1-13). [PMID:39779633] [10.1208/s12249-024-03015-1] |
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