JavaScript 似乎在您的浏览器中禁用。 在我们的网站上获得最佳体验，请务必打开 Javascript 在您的浏览器。

为了获得访问"阿拉丁铁蛋"实时聊天框的流畅支持体验，建议您使用Chrome浏览器或选择360浏览器极速模式(如何切换极速模式?)，感谢您选择我们！

切换导航

我的购物车

搜索

(±)-吴茱萸碱

规格或纯度: 98%

CAS编号: 518-18-3
分子式: C₁₉H₁₇N₃O
分子量: 303.37
PubChem编号: 151289

有货

库存信息

关闭

库存信息

关闭

库存信息

关闭

货号 (SKU)	包装规格	是否现货	价格	数量
E140884-1g	1g	现货
E140884-5g	5g	现货
E140884-25g	25g	现货

Skip to the end of the images gallery

main product photo

Skip to the beginning of the images gallery

基本描述

别名	吴茱萸胺
英文别名	XE178590\|AS-15078\|HY-N0114A\|NCGC00163553-02\|SureCN682158\|FT-0651829\|Evodiamine, Evodia rutaecarpa\|NSC258314\|NSC-258314\|Evodiamine;\|NCGC00163553-03\|Q5418554\|PubChem18244\|(1S)-21-methyl-3,13,21-triazapentacyclo[11.8.0.0^{2,10.0^{4,9.0^{15,20]henicosa-2(10),
规格或纯度	98%
英文名称	(±)-Evodiamine
生化机理	The interferon-γ priming signal regulating the transcriptional activation of the iNOS gene is blocked by Evodiamine, suppressing iNOS protein synthesis but not affecting iNOS function. Evodiamine also demonstrates antiangiogenesis throμgh inhibition of vascular endothelial growth factor gene expression and inhibition of the ERK 1 (p44)/ERK 2 (p42) mitogen-activated protein kinase that correlated to endothelial cell angiogenesis. Promotion of apoptosis in human leukemic U937 cells is described with Evodiamine.
应用	An antiangiogenic and antiinflammatory agonist of TRPV1.
储存温度	2-8°C储存
运输条件	冰袋运输
产品介绍	Evodiamine is a quinozole alkaloid isolated from Evodia rutaecarpa, described as an agonist of the VR1 (vanilloid receptor subtype 1, TRPV1) with affinity (Ki = 5.95 microM) comparable to that of the prototypical VR1 chemical activator Capsaicin .Evodiamine induction of 45Ca2+ uptake was competitively antagonized by the Capsaicin antagonist Capsazepine .Evodiamine is described to inhibit prostaglandin E2 synthesis, cyclooxygenase-2 induction and NF-κB activation, producing antiinflammatory effects.An antiangiogenic and antiinflammatory agonist of TRPV1. Evodiamine is a quinozole alkaloid isolated from Evodia rutaecarpa, described as an agonist of the VR1 (vanilloid receptor subtype 1, TRPV1) with affinity (Ki = 5.95 microM) comparable to that of the prototypical VR1 chemical activator Capsaicin .Evodiamine induction of 45Ca2+ uptake was competitively antagonized by the Capsaicin antagonist Capsazepine .Evodiamine is described to inhibit prostaglandin E2 synthesis, cyclooxygenase-2 induction and NF-κB activation, producing antiinflammatory effects. An antiangiogenic and antiinflammatory agonist of TRPV1.

名称和标识符

IUPAC Name	21-methyl-3,13,21-triazapentacyclo[11.8.0.02,10.04,9.015,20]henicosa-2(10),4,6,8,15,17,19-heptaen-14-one
INCHI	InChI=1S/C19H17N3O/c1-21-16-9-5-3-7-14(16)19(23)22-11-10-13-12-6-2-4-8-15(12)20-17(13)18(21)22/h2-9,18,20H,10-11H2,1H3
InChi Key	TXDUTHBFYKGSAH-UHFFFAOYSA-N
Canonical SMILES	CN1C2C3=C(CCN2C(=O)C4=CC=CC=C41)C5=CC=CC=C5N3
Isomeric SMILES	CN1C2C3=C(CCN2C(=O)C4=CC=CC=C41)C5=CC=CC=C5N3
PubChem CID	151289
分子量	303.37
Reaxy-Rn	94484

化学和物理性质

溶解性	Soluble in DMSO (5 mg/mL,warm to 40°C), water (<1 mg/mL) at 25 °C, and ethanol (<1 mg/mL) at 25 °C
密度	1.39
敏感性	对光敏感
熔点	272°C(lit.)

安全和危险性（GHS）

Reaxy-Rn	94484

质检证书(COA)

质检报告(COA)

输入批号以搜索COA:

相关文档

质检报告COA

请输入批号:

SDS中文版 SDS英文版

质量技术规格说明书

相关技术文章

FAQ

吲哚合成：探索分子砌块的双面之路

分类: 技术文章

标签:

吲哚 Fischer Heck 抗癌药物免疫调节剂抗抑郁药抗炎药

产品问答

产品问答

登录提交问题

您提交该产品问题后,我们会在1-2个工作日内给您答复,您可以登录"我的账号",然后点击"我的产品问答"查看答案

上海阿拉丁生化科技股份有限公司

销售条款及条件隐私政策

© 2016 ALADDIN-E.COM . 版权所有,未经授权禁止拷贝本站资料,如有违反,将追究法律责任

沪公网安备 31012002004058号沪ICP备09093490号-2

本网站销售的所有产品仅用于工业应用或者科学研究等非医疗目的,不可用于人类或动物的临床诊断或者治疗,非药用,非食用。

危险品化学品经营许可证（带存储）

营业执照(三证合一)