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亚甲基蓝 水合物


规格或纯度: 用于生物学染色,Dye content, ≥90%(HPLC)
有货

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货号 (SKU) 包装规格 是否现货 价格 数量
M102717-1g
1g 现货 Stock Image
M102717-5g
5g 现货 Stock Image
M102717-25g
25g 现货 Stock Image
M102717-100g
100g 现货 Stock Image
M102717-500g
500g 现货 Stock Image

基本描述

别名 次甲基蓝|次甲基兰|亚甲基兰|亚甲蓝
英文别名 Methylene Blue trihydrate|7220-79-3|Methylthionine chloride|C.I. Basic Blue 9 trihydrate|Phenothiazin-5-ium, 3,7-bis(dimethylamino)-, chloride, trihydrate|Basic Blue 9 trihydrate|3,7-Bis(dimethylamino)phenothiazin-5-ium chloride trihydrate|7220-79-3 (hdyr
规格或纯度 用于生物学染色,Dye content, ≥90%(HPLC)
英文名称 Methylene blue
运输条件 常规运输
产品介绍

Methylene Blue acts as a GCS (guanylyl cyclase) inhibitor, biological stain and redox indicator. Methylene Blue inhibits tau filament formation. Additionally, Methylene Blue is also reported to inhibit NOSs (nitric oxide synthase). Methylene Blue is widely used to inhibit cGMP-mediated processes. Methylene Blue has been observed to dose-dependently induce cytotoxicity in U-373 MG human astrocytoma and SK-N-MC human neuroblastoma cells. Furthermore Methylene Blue is reported to bind to the M2 subtype of muscarinic receptors in rat cardiac myocytes, and thus exhibit antimuscarinic effects on IK, ACh and ICa. Methylene Blue has also been reported to inhibit endothelium-dependent relaxation of isolated blood vessels.An inhibitor of cGMP-mediated processes and guanylyl cyclase, a useful stain, and a redox indicator

Methylene Blue acts as a GCS (guanylyl cyclase) inhibitor, biological stain and redox indicator. Methylene Blue inhibits tau filament formation. Additionally, Methylene Blue is also reported to inhibit NOSs (nitric oxide synthase). Methylene Blue is widely used to inhibit cGMP-mediated processes. Methylene Blue has been observed to dose-dependently induce cytotoxicity in U-373 MG human astrocytoma and SK-N-MC human neuroblastoma cells. Furthermore Methylene Blue is reported to bind to the M2 subtype of muscarinic receptors in rat cardiac myocytes, and thus exhibit antimuscarinic effects on IK, ACh and ICa. Methylene Blue has also been reported to inhibit endothelium-dependent relaxation of isolated blood vessels.
An inhibitor of cGMP-mediated processes and guanylyl cyclase, a useful stain, and a redox indicator

名称和标识符

PubChem SID 488187373
PubChem SID url https://pubchem.ncbi.nlm.nih.gov/substance/488187373
EC号 200-515-2
IUPAC Name [7-(dimethylamino)phenothiazin-3-ylidene]-dimethylazanium;chloride;trihydrate
INCHI InChI=1S/C16H18N3S.ClH.3H2O/c1-18(2)11-5-7-13-15(9-11)20-16-10-12(19(3)4)6-8-14(16)17-13;;;;/h5-10H,1-4H3;1H;3*1H2/q+1;;;;/p-1
InChi Key XQAXGZLFSSPBMK-UHFFFAOYSA-M
Canonical SMILES CN(C)C1=CC2=C(C=C1)N=C3C=CC(=[N+](C)C)C=C3S2.O.O.O.[Cl-]
Isomeric SMILES CN(C)C1=CC2=C(C=C1)N=C3C=CC(=[N+](C)C)C=C3S2.O.O.O.[Cl-]
WGK Germany 2
PubChem CID 104827
分子量 373.9
Beilstein号 3599847

化学和物理性质

溶解性 Soluble in water (50 mg/ml), ethanol (70 mg/ml), alcohol, and chloroform. Insoluble in ether.
密度 1.14
熔点 235°C

安全和危险性(GHS)

象形图
ghs08

Health Hazard

ghs07

Harmful

信号词 Warning
危险声明 H315: Causes skin irritation
H319: Causes serious eye irritation
H335: May cause respiratory irritation
H373: Causes damage to organs through prolonged or repeated exposure
H302: Harmful if swallowed
预防措施声明 P261,P305+P351+P338,P280,P302+P352,P321,P405,P501,P264,P260,P271,P270,P304+P340,P403+P233,P362+P364,P330,P264+P265,P301+P317,P337+P317,P332+P317,P319
WGK Germany 2
个人防护装备 Eyeshields,Faceshields,full-face respirator (US),Gloves,multi-purpose combination respirator cartridge (US),type ABEK (EN14387) respirator filter

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