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| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| T114360-10mg |
10mg |
期货  |
|
| 别名 | 1-甲基-3-{3-甲基-4-[4-(三氟甲基磺酰)苯氧基]苯基}-1,3,5-三嗪-2,4,6(1H,3H,5H)-三酮 |
|---|---|
| 英文别名 | Ponazuril|Toltrazuril sulfone|69004-04-2|Toltrazuril (sulfone)|Marquis|1-Methyl-3-{3-methyl-4-[4-(trifluoromethylsulfonyl)phenoxy]phenyl}-1,3,5-triazine-2,4,6(1H,3H,5H)-trione|Ponazuril [INN]|UNII-JPW84AS66U|JPW84AS66U|BAY-Vi 9143|1-methyl-3-[3-methyl-4-[ |
| 规格或纯度 | 分析标准品 |
| 英文名称 | Toltrazuril sulfone |
| 生化机理 |
Ponazuril (INN, Toltrazuril sulfone), sold by the Bayer Corporation under the trade name Marquis, is a drμg currently approved for the treatment of equine protozoal myeloencephalitis in horses, caused by Sarcocystis neurona. More recently, veterinarians have been preparing a formulary version of the medication for use in small animals such as cats and dogs against coccidia, an intestinal parasite. Coccidia treatment is far shorter than treatment for EPM. Ponazuril (INN, Toltrazuril sulfone) is useful for Antiprotozoal. |
| 运输条件 | 常规运输 |
| IUPAC Name | 1-methyl-3-[3-methyl-4-[4-(trifluoromethylsulfonyl)phenoxy]phenyl]-1,3,5-triazinane-2,4,6-trione |
|---|---|
| INCHI | InChI=1S/C18H14F3N3O6S/c1-10-9-11(24-16(26)22-15(25)23(2)17(24)27)3-8-14(10)30-12-4-6-13(7-5-12)31(28,29)18(19,20)21/h3-9H,1-2H3,(H,22,25,26) |
| InChi Key | VBUNOIXRZNJNAD-UHFFFAOYSA-N |
| Canonical SMILES | CC1=C(C=CC(=C1)N2C(=O)NC(=O)N(C2=O)C)OC3=CC=C(C=C3)S(=O)(=O)C(F)(F)F |
| Isomeric SMILES | CC1=C(C=CC(=C1)N2C(=O)NC(=O)N(C2=O)C)OC3=CC=C(C=C3)S(=O)(=O)C(F)(F)F |
| PubChem CID | 3050408 |
| 分子量 | 457.38 |
| PubChem CID | 3050408 |
|---|---|
| ChEMBL Ligand | CHEMBL2104856 |
| DrugBank Ligand | DB11452 |
| CAS Registry No. | 69004-04-2 |
输入批号以搜索COA:
| 1. Kennedy T, Campbell J, Selzer V. (2001) Safety of ponazuril 15% oral paste in horses.. Vet Ther, 2 (3): (223-31). [PMID:19746665] |
| 2. Dahlström M, Madjid N, Nordvall G, Halldin MM, Vazquez-Juarez E, Lindskog M, Sandin J, Winblad B, Eriksdotter M, Forsell P. (2021) Identification of Novel Positive Allosteric Modulators of Neurotrophin Receptors for the Treatment of Cognitive Dysfunction.. Cells, 10 (8): (1871). [PMID:34440640] |
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