黄尿酸

选择性激活II型mGlu受体

规格或纯度: 96%

CAS编号: 59-00-7
分子式: C₁₀H₇NO₄
分子量: 205.17
Beilstein号: 185954
EC号: 200-410-1
MDL号: MFCD00006754
PubChem编号: 5699

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货号 (SKU)	包装规格	是否现货
X113958-250mg	250mg	期货
X113958-1g	1g	期货
X113958-5g	5g	期货

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六元杂环化合物吡啶类

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基本描述

别名	4,8-二羟基喹啉-2-羧酸\|4,8-二羟基喹啉甲酸\|4,8-二羟基喹啉-2-甲酸
英文别名	xanthurenic acid\|59-00-7\|4,8-Dihydroxyquinoline-2-carboxylic acid\|Xanthuric acid\|8-Hydroxykynurenic acid\|Xanthurenate\|4,8-Dihydroxyquinaldic acid\|4,8-Dihydroxyquinaldinic acid\|8-hydroxy-4-oxo-1H-quinoline-2-carboxylic acid\|2-Quinolinecarboxylic acid, 4,8-
规格或纯度	96%
英文名称	Xanthurenic acid
生化机理	显示以纳摩尔浓度选择性激活转染的HEK293细胞中的II型mGlu受体。减轻表达mGlu2和mGlu3受体的小鼠皮质切片中cAMP的形成。
运输条件	常规运输
产品介绍	应用：黄尿酸可用作合成以下物质的底物：以硅胶功能化修饰的黄尿酸 (4, 8-二羟基喹啉-2-羧酸)，其可作为金属离子吸附剂。通过一锅Mannich 反应制备N, N′-双-((8-羟基-7-喹啉基)甲基)-1,10-二氮杂-18-冠-6 醚，其可作为活细胞中镁的荧光传感器用于生物传感应用的聚黄尿酸（poly-Xa）。

名称和标识符

EC号	200-410-1
IUPAC Name	8-hydroxy-4-oxo-1H-quinoline-2-carboxylic acid
INCHI	InChI=1S/C10H7NO4/c12-7-3-1-2-5-8(13)4-6(10(14)15)11-9(5)7/h1-4,12H,(H,11,13)(H,14,15)
InChi Key	FBZONXHGGPHHIY-UHFFFAOYSA-N
Canonical SMILES	C1=CC2=C(C(=C1)O)NC(=CC2=O)C(=O)O
Isomeric SMILES	C1=CC2=C(C(=C1)O)NC(=CC2=O)C(=O)O
WGK Germany	3
RTECS	UZ9275000
PubChem CID	5699
分子量	205.17
Beilstein号	185954
Reaxy-Rn	185954

化学和物理性质

溶解性	溶于DMSO, 最高浓度 (mg/mL): 20.52, 最高浓度(mM): 100
密度	1.569
熔点	297-298°C

安全和危险性（GHS）

象形图	Harmful
信号词	Warning
危险声明	H315: Causes skin irritation H319: Causes serious eye irritation H335: May cause respiratory irritation
预防措施声明	P261,P305+P351+P338,P280,P302+P352,P321,P405,P501,P264,P271,P304+P340,P403+P233,P362+P364,P264+P265,P337+P317,P332+P317,P319
WGK Germany	3
RTECS	UZ9275000
Reaxy-Rn	185954
Merck Index	10068
个人防护装备	dust mask type N95 (US)， Eyeshields， Gloves

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参考文献

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黄尿酸

库存信息

库存信息

库存信息

基本描述

名称和标识符

化学和物理性质

安全和危险性（GHS）

质检证书(COA)

质检报告(COA)

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参考文献