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去氢表雄酮

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货号 (SKU) 包装规格 是否现货 价格 数量
D106380-1g
 1g 现货 Stock Image
D106380-5g
 5g 现货 Stock Image
D106380-25g
 25g 现货 Stock Image
D106380-100g
 100g 现货 Stock Image
D106380-500g
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Glycine Receptor (All subtypes) Subunit-specific (19)
main product photo

基本描述

别名 3β-羟基-5-雄烯-17-酮 | 去氢表雄酮 | 普拉睾酮 | 脱氢异雄酮 | 雄素-5-烯-3β-醇-17-酮 | 脱氢表雄酮 | 去氢表雄酮 | 脱氢表雄甾酮 | 脱氢表雄至素酮 | 脱氢异雄酮 | 反式-脱氢异雄甾酮 | 反式-脱氢雄甾酮
英文别名 DHEA | A14AA07 | NCGC00093802-06 | BCPE00002 | Prasterone [INN] | 3beta-Hydroxy-D5-androsten-17-one | 5-Dehydroepiandrosterone | 5-dehydro-Epiandrosterone | bmse000665 | Intrarosa | Lopac0_000368 | Biolaif (TN) | D5-Androsten-3b-ol-17-one | Prasterone [US
规格或纯度 Moligand™, ≥99%
英文名称 trans-Dehydroandrosterone
生化机理 GABAA 受体的负调节剂。肾上腺分泌的类固醇，具有雌激素和雄激素特性。 它转化为 5-雄烯二醇（一种有效的雌激素）可增强雌激素敏感性乳腺肿瘤的生长和存活率。在高浓度但生理有效的条件下，DHEA 抑制嗜铬细胞祖细胞的增殖并诱导多巴胺能分化。 脱氢雄激素（DHEA）是 GABAA 受体的负调节剂。它是肾上腺分泌的类固醇，具有雌激素和雄激素特性。 脱氢表雄酮（DHEA）转化为 5-雄烯二醇（一种有效的雌激素）可增强雌激素敏感性乳腺肿瘤的生长和存活率。
应用 去氢表雄酮用于制造甾体激素类药物的中间体，具有抗衰老及蛋白同化作用。
运输条件 常规运输
产品介绍

去氢表雄酮用于制造甾体激素类药物的中间体，具有抗衰老及蛋白同化作用。

AI解读

产品属性

ALogP 3.2

关联靶点（人）

SHBG Tchem 性激素结合球蛋白(Sex hormone-binding globulin) (1 活性数据)
活性类型 活性值-log(M) 作用机制 期刊 参考文献(PubMed IDs)
VDR Tclin Vitamin D receptor (26531 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
MAOA Tclin Monoamine oxidase A (11911 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
NPC1L1 Tclin Niemann-Pick C1-like protein 1 (346 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
SULT2A1 Tbio Alcohol sulfotransferase (89 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
SERPINA6 Tchem Corticosteroid binding globulin (274 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
UGT1A4 Tbio UDP-glucuronosyltransferase 1A4 (288 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CYP3A4 Tclin Cytochrome P450 3A4 (53859 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
A-375 (9258 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ACHN (49357 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CAKI-1 (44928 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
COLO 205 (50209 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Daoy (570 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
DU-145 (51482 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
HL-60 (67320 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
HT-29 (80576 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
KM12 (47707 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
M14 (47487 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
MCF7 (126967 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
MDA-MB-468 (9477 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
MOLT-4 (49676 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
OVCAR-3 (48710 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
OVCAR-4 (44535 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
OVCAR-5 (45555 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
OVCAR-8 (47708 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
PC-3 (62116 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
RPMI-8226 (44974 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
RXF 393 (41971 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
SF-295 (48000 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
SK-MEL-2 (46422 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
SK-MEL-28 (48833 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
SK-MEL-5 (47095 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
SK-OV-3 (52876 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
SN12C (47755 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
SNB-19 (46794 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
SW480 (6023 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
TK-10 (45540 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
U-251 (51189 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
UACC-257 (46019 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
UACC-62 (47335 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
UO-31 (46270 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
786-0 (47912 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
A549 (127892 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
NCI/ADR-RES (33767 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
T47D (39041 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
EKVX (44102 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
A-431 (6446 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
HCC 2998 (41480 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
HCT-116 (91556 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Hs-578T (29457 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
WiDr (1835 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

关联靶点（其它种属）

Gusb Beta-glucuronidase (17 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Nr1i3 Constitutive androstane receptor (427 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Shbg Testis-specific androgen-binding protein (10 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
SULT1E1 Estrogen sulfotransferase (8 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Pseudomonas aeruginosa (123386 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Klebsiella pneumoniae (43867 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Staphylococcus aureus (210822 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Acinetobacter baumannii (41033 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Escherichia coli (133304 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Trypanosoma brucei (78846 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Plasmodium falciparum (966862 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Cryptococcus neoformans (21258 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Candida albicans (78123 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Leishmania mexicana (936 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Trypanosoma cruzi (99888 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
J774.A1 (2436 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
PC-12 (7051 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
J774.2 (197 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
rep Replicase polyprotein 1ab (378 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
NS1 Nonstructural protein 1 (33327 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Slco1a3 Solute carrier organic anion transporter family member 1A3 (65 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
SARS-CoV-2 (38078 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

作用机制

作用机制 Action Type target ID Target Name Target Type Target Organism Binding Site Name 参考文献

名称和识别符

EC号 200-175-5
分子类型 小分子
IUPAC Name (3S,8R,9S,10R,13S,14S)-3-hydroxy-10,13-dimethyl-1,2,3,4,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-17-one
INCHI InChI=1S/C19H28O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h3,13-16,20H,4-11H2,1-2H3/t13-,14-,15-,16-,18-,19-/m0/s1
InChi Key FMGSKLZLMKYGDP-USOAJAOKSA-N
Canonical SMILES CC12CCC3C(C1CCC2=O)CC=C4C3(CCC(C4)O)C
Isomeric SMILES C[C@]12CC[C@H]3[C@H]([C@@H]1CCC2=O)CC=C4[C@@]3(CC[C@@H](C4)O)C
WGK Germany 2
RTECS BV8396000
PubChem CID 5881
分子量 288.43
Beilstein号 2058110

化学和物理性质

密度 1.12
熔点 146-151°C
分子量 288.400 g/mol
XLogP3 3.200
氢键供体数Hydrogen Bond Donor Count 1
氢键受体数Hydrogen Bond Acceptor Count 2
可旋转键计数Rotatable Bond Count 0
精确质量Exact Mass 288.209 Da
单同位素质量Monoisotopic Mass 288.209 Da
拓扑极表面积Topological Polar Surface Area 37.300 Ų
重原子数Heavy Atom Count 21
形式电荷Formal Charge 0
复杂度Complexity 508.000
同位素原子数Isotope Atom Count 0
定义的原子立体中心计数Defined Atom Stereocenter Count 6
未定义的原子立体中心计数Undefined Atom Stereocenter Count 0
定义的键立体中心计数Defined Bond Stereocenter Count 0
未定义的键立体中心计数Undefined Bond Stereocenter Count 0
所有立体化学键的总数The total count of all stereochemical bonds 0
共价键合单元计数Covalently-Bonded Unit Count 1

安全和危险性（GHS）

象形图 GHS08,   GHS09,   GHS07
信号词 Danger
危险声明

H315: 引起皮肤刺激

H319: 引起严重眼睛刺激

H335: 可能引起呼吸道刺激

H400: 对水生生物有剧毒

H410: 对水生生物有剧毒并具有长期持续影响

H360: 可能损害生育力或未出生的孩子

H362: 可能对母乳喂养的孩子造成伤害
预防措施声明

P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾

P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。

P273: 避免释放到环境中。

P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。

P302+P352: 如皮肤沾染：用水充分清洗。

P321: 特殊处理（请参阅此标签上的...）。

P405: 密闭存放

P501: 将内容物/容器处理到。。。

P264: 处理后要彻底洗手。

P260: 不要吸入灰尘/烟雾/气体/雾/蒸汽/喷雾。

P271: 仅在室外或通风良好的地方使用。

P270: 使用本产品时，请勿进食、饮水或吸烟。

P304+P340: 如误吸入：将人转移到空气新鲜处，保持呼吸舒适体位。

P403+P233: 存放在通风良好的地方。保持容器密闭。

P362+P364: 脱掉沾污的衣服，清洗后方可重新使用。

P391: 收集溢出物

P263: 避免在怀孕期间/哺乳期间接触。

P203: 使用前，获取、阅读并遵守所有安全说明。

P264+P265: 处理后彻底洗手[和…]。不要触摸眼睛。

P318: 如果暴露或担心，请就医。

P337+P317: 如果眼睛刺激持续：寻求医疗帮助。

P332+P317: 如果出现皮肤刺激：请寻求医疗帮助。

P319: 如果你感到不适，请寻求医疗帮助。
WGK Germany 2
RTECS BV8396000

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批号(Lot Number) 证书类型 日期 货号
L2410028 分析证书 24-11-09 D106380
K2426458 分析证书 24-11-09 D106380
K2426433 分析证书 24-11-09 D106380
K2426432 分析证书 24-11-09 D106380
F2421217 分析证书 24-06-06 D106380
J2431150 分析证书 24-06-06 D106380
F2421219 分析证书 24-06-06 D106380
F2421218 分析证书 24-06-06 D106380
F2421216 分析证书 24-06-06 D106380
F2421215 分析证书 24-06-06 D106380
J2431677 分析证书 24-03-21 D106380
J2431676 分析证书 24-03-21 D106380
J2431675 分析证书 24-03-21 D106380
E2324271 分析证书 23-09-16 D106380
A2403044 分析证书 23-07-31 D106380
H2316371 分析证书 23-07-31 D106380
H2316370 分析证书 23-07-31 D106380
H2316369 分析证书 23-07-31 D106380
H2316367 分析证书 23-07-31 D106380
H2316368 分析证书 23-07-31 D106380
F2315991 分析证书 23-06-29 D106380
A2220037 分析证书 22-02-17 D106380
E2207019 分析证书 22-02-14 D106380
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L2216807 分析证书 22-02-14 D106380
A2221040 分析证书 22-01-27 D106380
E1618016 分析证书 22-01-24 D106380
C1829062 分析证书 22-01-24 D106380

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9. Jing Cong, Yuehui Zhang, Xinming Yang, Yu Wang, Hui He, Mengying Wang.  (2022)  Anti-polycystic ovary syndrome effect of electroacupuncture: IMD inhibits ER stress-mediated apoptosis and autophagy in granulosa cells.  BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,  634  (159).  [PMID:36244114] [10.1016/j.bbrc.2022.10.030]
10. Ying Wang Yu Wang Yao Chen Qianqian Gao Lihui Hou Xiaoling Feng.  (2022)  HDAC5 inhibits ovarian angiogenesis in dehydroepiandrosterone-induced mouse model of polycystic ovary syndrome.  FOLIA HISTOCHEMICA ET CYTOBIOLOGICA,  60  (3): (260-270).  [PMID:36124413] [10.5603/FHC.a2022.0024]
11. Xiao-San Li, Mao-Xun Yang, Yu-Hao Luo, He-Hui Zhan, Mei-Fang Chen, Yong-Mei Huang, Li Liu, Xue-Mei Yang.  (2022)  Design, Synthesis and Anticancer Activity of Novel Steroidal Derivatives with D-Ring Fused or Substituted N-Heterocyclic Systems.  CHEMISTRY & BIODIVERSITY,  19  (10): (e202200648).  [PMID:36043381] [10.1002/cbdv.202200648]
12. Jing Xia, Shujuan Wu, Gengxiang Wu, Jing Yang.  (2022)  Inhibition of 8-oxoguanine DNA glycosylase (OGG1) expression suppresses polycystic ovarian syndrome via the NF-κB signaling pathway.  Reproductive Biology,  22  (100679).  [PMID:35961097] [10.1016/j.repbio.2022.100679]
13. Ying-Li Cai, Feng Zhang, Xiu-Xiu Dou, Hua-Wu Zeng, Gao-Song Wu, Yan-Lin Liang, Xi-Ke Xu, Jing Zhao, Ji Ye, Wei-Dong Zhang.  (2022)  Integrated metabolomics and network pharmacology to reveal the therapeutic mechanism of Dingkun Pill on polycystic ovary syndrome.  JOURNAL OF ETHNOPHARMACOLOGY,  295  (115442).  [PMID:35688255] [10.1016/j.jep.2022.115442]
14. Huiyi Yang, Qiyi He, Mingxia Lin, Li Ji, Leheng Zhang, Huanxin Xiao, Shijia Li, Qinglan Li, Xiping Cui, Suqing Zhao.  (2022)  Multifunctional Au@Pt@Ag NPs with color-photothermal-Raman properties for multimodal lateral flow immunoassay.  JOURNAL OF HAZARDOUS MATERIALS,  435  (129082).  [PMID:35650752] [10.1016/j.jhazmat.2022.129082]
15. Susu Lin, Bingbing Ma, Qilin Gao, Jian Yang, Gang Lai, Runhao Lin, Bingxian Yang, Bing-Nan Han, Lian-Hua Xu.  (2022)  The 16α-Hydroxylation of Progesterone by Cytochrome P450 107X1 from Streptomyces avermitilis.  CHEMISTRY & BIODIVERSITY,  19  (5): (e202200177).  [PMID:35426465] [10.1002/cbdv.202200177]
16. Yan Li, Jia Xu, Lingxia Li, Lu Bai, Yunping Wang, Jianfang Zhang, Haixu Wang.  (2022)  Inhibition of Nicotinamide adenine dinucleotide phosphate oxidase 4 attenuates cell apoptosis and oxidative stress in a rat model of polycystic ovary syndrome through the activation of Nrf-2/HO-1 signaling pathway.  MOLECULAR AND CELLULAR ENDOCRINOLOGY,  550  (111645).  [PMID:35413388] [10.1016/j.mce.2022.111645]
17. Huiyi Yang, Qiyi He, Junkang Pan, Mingxia Lin, Zhiting Lao, Qinglan Li, Xiping Cui, Suqing Zhao.  (2022)  PtCu nanocages with superior tetra-enzyme mimics for colorimetric sensing and fluorescent sensing dehydroepiandrosterone.  SENSORS AND ACTUATORS B-CHEMICAL,  351  (130905).  [10.1016/j.snb.2021.130905]
18. Yang Huiyi, He Qiyi, Eremin Sergei A., Pan Junkang, Zou Yikui, Cui Xiping, Zhao Suqing.  (2021)  Fluorescence polarization immunoassay for rapid determination of dehydroepiandrosterone in human urine.  ANALYTICAL AND BIOANALYTICAL CHEMISTRY,  413  (17): (4459-4469).  [PMID:34137913] [10.1007/s00216-021-03403-7]
19. Yang Huiyi, He Qiyi, Chen Yingshan, Shen Ding, Xiao Huanxin, Eremin Sergei A., Cui Xiping, Zhao Suqing.  (2020)  Platinum nanoflowers with peroxidase-like property in a dual immunoassay for dehydroepiandrosterone.  MICROCHIMICA ACTA,  187  (11): (1-12).  [PMID:33025211] [10.1007/s00604-020-04528-9]
20. Jun Liu, Jinli Ding, Bing Qu, Jiuying Liu, Xiaojie Song, Qingli Suo, Aifen Zhou, Jing Yang.  (2020)  CircPSMC3 alleviates the symptoms of PCOS by sponging miR-296-3p and regulating PTEN expression.  JOURNAL OF CELLULAR AND MOLECULAR MEDICINE,  24  (18): (11001-11011).  [PMID:32808450] [10.1111/jcmm.15747]
21. Gengxiang Wu, Xue Hu, Jinli Ding, Jing Yang.  (2020)  The effect of glutamine on Dehydroepiandrosterone-induced polycystic ovary syndrome rats..  Journal of Ovarian Research,  13  (1): (57-57).  [PMID:32386521] [10.1186/s13048-020-00650-7]
22. Ling-Li Zheng, Guan Wen, Yun-Xin Yao, Xiao-Huan Li, Feng Gao.  (2020)  Design, Synthesis, and Anticancer Activity of Natural Product Hybrids With Paclitaxel Side Chain Inducing Apoptosis in Human Colon Cancer Cells.  Natural Product Communications,  [10.1177/1934578X20917298]
23. Wu Gengxiang, Hu Xue, Ding Jinli, Yang Jing.  (2019)  Abnormal expression of HSP70 may contribute to PCOS pathology.  Journal of Ovarian Research,  12  (1): (1-7).  [PMID:31399035] [10.1186/s13048-019-0548-7]
24. Zhou Dan-ni, Li Sai-jiao, Ding Jin-li, Yin Tai-lang, Yang Jing, Ye Hong.  (2018)  MIF May Participate in Pathogenesis of Polycystic Ovary Syndrome in Rats through MAPK Signalling Pathway.  Current Medical Science,  38  (5): (853-860).  [PMID:30341520] [10.1007/s11596-018-1953-7]
25. Di Xu, Mengyun Wu, Xue Li, Mingyu Xia, Dongchun Liu, Yinghui Dai, Qing Yu, Bin Wu, Dong Wang.  (2018)  Cloning, prokaryotic expression and function of the Bufo bufo gargarizans 3β-hydroxysteroid dehydrogenase (3βHSD) gene.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,  120  (673).  [PMID:30170058] [10.1016/j.ijbiomac.2018.08.165]
26. Xianzhi Qu, Jiyao Sheng, Luyan Shen, Jing Su, Yunjie Xu, Qi Xie, Yao Wu, Xuewen Zhang, Liankun Sun.  (2017)  Autophagy inhibitor chloroquine increases sensitivity to cisplatin in QBC939 cholangiocarcinoma cells by mitochondrial ROS.  PLoS One,  12  (3): (e0173712).  [PMID:28301876] [10.1371/journal.pone.0173712]
27. Zhuang Wu, Linlang Li, Long-Tai Zheng, Zhihong Xu, Lin Guo, Xuechu Zhen.  (2015)  Allosteric modulation of sigma-1 receptors by SKF83959 inhibits microglia-mediated inflammation.  JOURNAL OF NEUROCHEMISTRY,  134  (5): (904-914).  [PMID:26031312] [10.1111/jnc.13182]
28. Teng-Fei Yuan,Juan Le,Yan Cui,Rui Peng,Shao-Ting Wang,Yan Li.  (2018-09-17)  An LC-MS/MS analysis for seven sex hormones in serum..  Journal of pharmaceutical and biomedical analysis,  162  (34-40).  [PMID:30219597]
29. Teng-Fei Yuan,Juan Le,Shao-Ting Wang,Yan Li.  (2020-01-23)  An LC/MS/MS method for analyzing the steroid metabolome with high accuracy and from small serum samples..  Journal of lipid research,  61  ((4)): (580-586).  [PMID:31964762]
30. Zhijing Song,Huanyu Gao,Wenchun Xie,Qing Sun,Kai Liang,Yan Li.  (2020-12-29)  Quantitative MALDI-MS assay of steroid hormones in plasma based on hydroxylamine derivatization..  Analytical biochemistry,  616  (114089-114089).  [PMID:33359147]
31. Yunjie Xu,Weinan Gao,Yong Zhang,Shanshan Wu,Yanan Liu,Xinyue Deng,Lili Xie,Jiayan Yang,Huimei Yu,Jing Su,Liankun Sun.  (2018-07-18)  ABT737 reverses cisplatin resistance by targeting glucose metabolism of human ovarian cancer cells..  International journal of oncology,  53  ((3)): (1055-1068).  [PMID:30015875]

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13. Ying-Li Cai, Feng Zhang, Xiu-Xiu Dou, Hua-Wu Zeng, Gao-Song Wu, Yan-Lin Liang, Xi-Ke Xu, Jing Zhao, Ji Ye, Wei-Dong Zhang.  (2022)  Integrated metabolomics and network pharmacology to reveal the therapeutic mechanism of Dingkun Pill on polycystic ovary syndrome.  JOURNAL OF ETHNOPHARMACOLOGY,  295  (115442).  [PMID:35688255] [10.1016/j.jep.2022.115442]
14. Huiyi Yang, Qiyi He, Mingxia Lin, Li Ji, Leheng Zhang, Huanxin Xiao, Shijia Li, Qinglan Li, Xiping Cui, Suqing Zhao.  (2022)  Multifunctional Au@Pt@Ag NPs with color-photothermal-Raman properties for multimodal lateral flow immunoassay.  JOURNAL OF HAZARDOUS MATERIALS,  435  (129082).  [PMID:35650752] [10.1016/j.jhazmat.2022.129082]
15. Susu Lin, Bingbing Ma, Qilin Gao, Jian Yang, Gang Lai, Runhao Lin, Bingxian Yang, Bing-Nan Han, Lian-Hua Xu.  (2022)  The 16α-Hydroxylation of Progesterone by Cytochrome P450 107X1 from Streptomyces avermitilis.  CHEMISTRY & BIODIVERSITY,  19  (5): (e202200177).  [PMID:35426465] [10.1002/cbdv.202200177]
16. Yan Li, Jia Xu, Lingxia Li, Lu Bai, Yunping Wang, Jianfang Zhang, Haixu Wang.  (2022)  Inhibition of Nicotinamide adenine dinucleotide phosphate oxidase 4 attenuates cell apoptosis and oxidative stress in a rat model of polycystic ovary syndrome through the activation of Nrf-2/HO-1 signaling pathway.  MOLECULAR AND CELLULAR ENDOCRINOLOGY,  550  (111645).  [PMID:35413388] [10.1016/j.mce.2022.111645]
17. Huiyi Yang, Qiyi He, Junkang Pan, Mingxia Lin, Zhiting Lao, Qinglan Li, Xiping Cui, Suqing Zhao.  (2022)  PtCu nanocages with superior tetra-enzyme mimics for colorimetric sensing and fluorescent sensing dehydroepiandrosterone.  SENSORS AND ACTUATORS B-CHEMICAL,  351  (130905).  [10.1016/j.snb.2021.130905]
18. Yang Huiyi, He Qiyi, Eremin Sergei A., Pan Junkang, Zou Yikui, Cui Xiping, Zhao Suqing.  (2021)  Fluorescence polarization immunoassay for rapid determination of dehydroepiandrosterone in human urine.  ANALYTICAL AND BIOANALYTICAL CHEMISTRY,  413  (17): (4459-4469).  [PMID:34137913] [10.1007/s00216-021-03403-7]
19. Yang Huiyi, He Qiyi, Chen Yingshan, Shen Ding, Xiao Huanxin, Eremin Sergei A., Cui Xiping, Zhao Suqing.  (2020)  Platinum nanoflowers with peroxidase-like property in a dual immunoassay for dehydroepiandrosterone.  MICROCHIMICA ACTA,  187  (11): (1-12).  [PMID:33025211] [10.1007/s00604-020-04528-9]
20. Jun Liu, Jinli Ding, Bing Qu, Jiuying Liu, Xiaojie Song, Qingli Suo, Aifen Zhou, Jing Yang.  (2020)  CircPSMC3 alleviates the symptoms of PCOS by sponging miR-296-3p and regulating PTEN expression.  JOURNAL OF CELLULAR AND MOLECULAR MEDICINE,  24  (18): (11001-11011).  [PMID:32808450] [10.1111/jcmm.15747]
21. Gengxiang Wu, Xue Hu, Jinli Ding, Jing Yang.  (2020)  The effect of glutamine on Dehydroepiandrosterone-induced polycystic ovary syndrome rats..  Journal of Ovarian Research,  13  (1): (57-57).  [PMID:32386521] [10.1186/s13048-020-00650-7]
22. Ling-Li Zheng, Guan Wen, Yun-Xin Yao, Xiao-Huan Li, Feng Gao.  (2020)  Design, Synthesis, and Anticancer Activity of Natural Product Hybrids With Paclitaxel Side Chain Inducing Apoptosis in Human Colon Cancer Cells.  Natural Product Communications,  [10.1177/1934578X20917298]
23. Wu Gengxiang, Hu Xue, Ding Jinli, Yang Jing.  (2019)  Abnormal expression of HSP70 may contribute to PCOS pathology.  Journal of Ovarian Research,  12  (1): (1-7).  [PMID:31399035] [10.1186/s13048-019-0548-7]
24. Zhou Dan-ni, Li Sai-jiao, Ding Jin-li, Yin Tai-lang, Yang Jing, Ye Hong.  (2018)  MIF May Participate in Pathogenesis of Polycystic Ovary Syndrome in Rats through MAPK Signalling Pathway.  Current Medical Science,  38  (5): (853-860).  [PMID:30341520] [10.1007/s11596-018-1953-7]
25. Di Xu, Mengyun Wu, Xue Li, Mingyu Xia, Dongchun Liu, Yinghui Dai, Qing Yu, Bin Wu, Dong Wang.  (2018)  Cloning, prokaryotic expression and function of the Bufo bufo gargarizans 3β-hydroxysteroid dehydrogenase (3βHSD) gene.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,  120  (673).  [PMID:30170058] [10.1016/j.ijbiomac.2018.08.165]
26. Xianzhi Qu, Jiyao Sheng, Luyan Shen, Jing Su, Yunjie Xu, Qi Xie, Yao Wu, Xuewen Zhang, Liankun Sun.  (2017)  Autophagy inhibitor chloroquine increases sensitivity to cisplatin in QBC939 cholangiocarcinoma cells by mitochondrial ROS.  PLoS One,  12  (3): (e0173712).  [PMID:28301876] [10.1371/journal.pone.0173712]
27. Zhuang Wu, Linlang Li, Long-Tai Zheng, Zhihong Xu, Lin Guo, Xuechu Zhen.  (2015)  Allosteric modulation of sigma-1 receptors by SKF83959 inhibits microglia-mediated inflammation.  JOURNAL OF NEUROCHEMISTRY,  134  (5): (904-914).  [PMID:26031312] [10.1111/jnc.13182]
28. Teng-Fei Yuan,Juan Le,Yan Cui,Rui Peng,Shao-Ting Wang,Yan Li.  (2018-09-17)  An LC-MS/MS analysis for seven sex hormones in serum..  Journal of pharmaceutical and biomedical analysis,  162  (34-40).  [PMID:30219597]
29. Teng-Fei Yuan,Juan Le,Shao-Ting Wang,Yan Li.  (2020-01-23)  An LC/MS/MS method for analyzing the steroid metabolome with high accuracy and from small serum samples..  Journal of lipid research,  61  ((4)): (580-586).  [PMID:31964762]
30. Zhijing Song,Huanyu Gao,Wenchun Xie,Qing Sun,Kai Liang,Yan Li.  (2020-12-29)  Quantitative MALDI-MS assay of steroid hormones in plasma based on hydroxylamine derivatization..  Analytical biochemistry,  616  (114089-114089).  [PMID:33359147]
31. Yunjie Xu,Weinan Gao,Yong Zhang,Shanshan Wu,Yanan Liu,Xinyue Deng,Lili Xie,Jiayan Yang,Huimei Yu,Jing Su,Liankun Sun.  (2018-07-18)  ABT737 reverses cisplatin resistance by targeting glucose metabolism of human ovarian cancer cells..  International journal of oncology,  53  ((3)): (1055-1068).  [PMID:30015875]

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