2-(4-羟苯基)乙醇

有货

库存信息

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库存信息

关闭
货号 (SKU) 包装规格 是否现货 价格 数量
H118576-100mg
100mg 现货 Stock Image
H118576-500mg
500mg 现货 Stock Image

基本描述

别名 对羟基苯乙醇, 4-羟基苯乙醇
英文别名 4-(2-Hydroxyethyl)phenol | 4-Hydroxyphenylethanol | 4-Hydroxybenzeneethanol | 4-Hydroxyphenethyl alcohol | 2-(4-Hydroxyphenyl)ethyl Alcohol | p-Tyrosol | Tyrosol | p-Hydroxyphenethyl alcohol
规格或纯度 色谱标准品, ≥99.5%(GC)
英文名称 2-(4-Hydroxyphenyl)ethanol
生化机理 橄榄油中的抗氧化剂。
储存温度 充氩
运输条件 常规运输
产品介绍

2-(4-羟基苯基)乙醇是一种存在于橄榄中的酚类化合物,具有广泛的健康益处和药理特性,例如抗炎、抗病毒、抗肿瘤和心脏保护活性。

应用:
2-(4-羟基苯基)乙醇可用作分析标准品,用于通过各种色谱技术测定白色念珠菌的培养上清液、内生真菌的液体察氏(Czapek)培养基培养物、人类生物样品和葡萄酒样品中的分析物。

2-(4-Hydroxyphenyl)ethanol is a phenolic compound present in olives, which can exhibit a wide range of health benefits and pharmacological properties like anti-inflammatory, antiviral, anti-tumor and cardioprotection activity.

Application:

2-(4-Hydroxyphenyl)ethanol may be used as an analytical standard for the determination of the analyte in culture supernatant of Candida albicans, liquid Czapek cultures from endophytic fungi, human biological samples, and wine samples by various chromatography techniques.

AI解读

关联靶点(人)

CA2 Tclin Carbonic anhydrase II (17698 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ALOX5 Tclin Arachidonate 5-lipoxygenase (6568 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
TYR Tclin Tyrosinase (717 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CA1 Tclin Carbonic anhydrase I (13240 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CA5B Tclin Carbonic anhydrase VB (957 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CA5A Tclin Carbonic anhydrase VA (1168 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
MET Tclin Hepatocyte growth factor receptor (10718 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
MCF-10A (2462 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
MDA-MB-468 (9477 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
MM96L (154 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
PANC-1 (6144 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
PC-3 (62116 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
SH-SY5Y (11521 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
SW480 (6023 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
HeLa (62764 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
MDA-MB-231 (73002 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
NTRK2 Tclin Neurotrophic tyrosine kinase receptor type 2 (3279 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
GLS Tchem Glutaminase kidney isoform, mitochondrial (16997 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

关联靶点(其它种属)

Carbonic anhydrase (69 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Saccharomyces cerevisiae (19171 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Spinacia oleracea (250 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Choristoneura fumiferana (12 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
N2a (708 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
PC-12 (7051 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
rep Replicase polyprotein 1ab (378 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
mtcA1 Uncharacterized protein Rv1284/MT1322 (182 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
PROBABLE TRANSMEMBRANE CARBONIC ANHYDRASE (CARBONATE DEHYDRATASE) (CARBONIC DEHYDRATASE) (107 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CAN2 Carbonic anhydrase 2 (140 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Verticillium dahliae (119 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
SARS-CoV-2 (38078 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

作用机制

作用机制 Action Type target ID Target Name Target Type Target Organism Binding Site Name 参考文献

名称和识别符

EC号 207-930-8
分子类型 小分子
IUPAC Name 4-(2-hydroxyethyl)phenol
INCHI InChI=1S/C8H10O2/c9-6-5-7-1-3-8(10)4-2-7/h1-4,9-10H,5-6H2
InChi Key YCCILVSKPBXVIP-UHFFFAOYSA-N
Canonical SMILES C1=CC(=CC=C1CCO)O
Isomeric SMILES C1=CC(=CC=C1CCO)O
WGK Germany 3
PubChem CID 10393
分子量 138.16
Beilstein号 1859884
Reaxy-Rn 1859884

化学和物理性质

密度 1.168
沸点 310°C
熔点 90-95°C
分子量 138.160 g/mol
XLogP3 0.400
氢键供体数Hydrogen Bond Donor Count 2
氢键受体数Hydrogen Bond Acceptor Count 2
可旋转键计数Rotatable Bond Count 2
精确质量Exact Mass 138.068 Da
单同位素质量Monoisotopic Mass 138.068 Da
拓扑极表面积Topological Polar Surface Area 40.500 Ų
重原子数Heavy Atom Count 10
形式电荷Formal Charge 0
复杂度Complexity 85.300
同位素原子数Isotope Atom Count 0
定义的原子立体中心计数Defined Atom Stereocenter Count 0
未定义的原子立体中心计数Undefined Atom Stereocenter Count 0
定义的键立体中心计数Defined Bond Stereocenter Count 0
未定义的键立体中心计数Undefined Bond Stereocenter Count 0
所有立体化学键的总数The total count of all stereochemical bonds 0
共价键合单元计数Covalently-Bonded Unit Count 1

安全和危险性(GHS)

象形图 GHS07
危险声明

H315: 引起皮肤刺激

H319: 引起严重眼睛刺激

H335: 可能引起呼吸道刺激

预防措施声明

P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾

P305+P351+P338: 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。

WGK Germany 3
Reaxy-Rn 1859884
个人防护装备 dust mask type N95 (US),Eyeshields,Gloves

质检证书(CoA,COO,BSE/TSE 和分析图谱)

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找到4个结果

批号(Lot Number) 证书类型 日期 货号
F2414098 分析证书 24-06-19 H118576
F2414243 分析证书 24-06-19 H118576
F1208031 分析证书 24-02-21 H118576
D2320043 分析证书 23-04-25 H118576

此产品的引用文献

1. Chenchen Zhao, Yu Sha, Wei Zhuang, Yuan Rao, Jihang Zhang, Jinglan Wu, Tao Shen, Zhuotao Tan, Chenjie Zhu, Hongman Zhang, Hanjie Ying.  (2023)  Production of hydroxytyrosol from tyrosol via controllable oxidation with immobilized tyrosinase: A comparative study.  PROCESS BIOCHEMISTRY,  131  (144).  [10.1016/j.procbio.2023.06.017]
2. Tong Sun, Yan Liu, Ke Wang, Feiyu Duan, Lili Lu.  (2023)  Biotransformation of Tyrosol into a Novel Valuable α-Galactoside with Increased Solubility and Improved Anti-inflammatory Activities.  JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,  71  (25): (9836–9846).  [PMID:37319317] [10.1021/acs.jafc.3c02529]
3. Jue Chen, Qibin Cheng, Qianqian Ma, Yuqi Wu, Liwei Zhang.  (2023)  Salidroside synthesis via glycosylation by β-D-glucosidase immobilized on chitosan microspheres in deep eutectic solvents.  BIOCATALYSIS AND BIOTRANSFORMATION,  [10.1080/10242422.2023.2178308]
4. Fengxia Tang, Chuan Li, Xiaoran Yang, Jiandu Lei, Hongxia Chen, Changwei Zhang, Chengzhang Wang.  (2023)  Effect of Variety and Maturity Index on the Physicochemical Parameters Related to Virgin Olive Oil from Wudu (China).  Foods,  12  (1): (7).  [PMID:36613224] [10.3390/foods12010007]
5. Jinbin Liu, Kaipeng Wang, Mian Wang, Huaxiang Deng, Xiaodong Chen, Yueling Shang, Xiaochen Liu, Xiaohong Yu.  (2022)  Efficient whole cell biotransformation of tyrosol from L-tyrosine by engineered Escherichia coli.  ENZYME AND MICROBIAL TECHNOLOGY,  160  (110100).  [PMID:35872508] [10.1016/j.enzmictec.2022.110100]
6. Li Jiang, Yanling Xiong, Yu Tu, Wentong Zhang, Qiyun Zhang, Peng Nie, Xiaojun Yan, Hongning Liu, Ronghua Liu, Guoliang Xu.  (2022)  Elucidation of the Transport Mechanism of Puerarin and Gastrodin and Their Interaction on the Absorption in a Caco-2 Cell Monolayer Model.  MOLECULES,  27  (4): (1230).  [PMID:35209020] [10.3390/molecules27041230]
7. Xu Yu, Li Yu, Fei Ma, Peiwu Li.  (2021)  Quantification of phenolic compounds in vegetable oils by mixed-mode solid-phase extraction isotope chemical labeling coupled with UHPLC-MS/MS.  FOOD CHEMISTRY,  334  (127572).  [PMID:32721834] [10.1016/j.foodchem.2020.127572]
8. Wenjing Li, Congyong Sun, Wenwen Deng, Yingkun Liu, Michael Adu-Frimpong, Jiangnan Yu, Ximing Xu.  (2019)  Pharmacokinetic of gastrodigenin rhamnopyranoside from Moringa seeds in rodents.  FITOTERAPIA,  138  (104348).  [PMID:31470062] [10.1016/j.fitote.2019.104348]
9. Jiahong Han, Min Dai, Yan Zhao, Enbo Cai, Lianxue Zhang, Xiaohuan Jia, Nian Sun, Xuan Fei, Hui Shu.  (2020)  Compatibility effects of ginseng and Ligustrum lucidum Ait herb pair on hematopoietic recovery in mice with cyclophosphamide-induced myelosuppression and its material basis.  Journal of Ginseng Research,  44  (291).  [PMID:32148411] [10.1016/j.jgr.2019.01.001]
10. Zhihua Liao, Fei Qiu, Junlan Zeng, Li Gu, Bangjun Wang, Xiaozhong Lan, Min Chen.  (2018)  A Novel UDP-Glycosyltransferase of Rhodiola crenulata Converts Tyrosol to Specifically Produce Icariside D2.  Biomed Research International,  2018  (7970590).  [PMID:30027099] [10.1155/2018/7970590]
11. Xianglai Li, Zhenya Chen, Yifei Wu, Yajun Yan, Xinxiao Sun, Qipeng Yuan.  (2018)  Establishing an Artificial Pathway for Efficient Biosynthesis of Hydroxytyrosol.  ACS Synthetic Biology,  (2): (647–654).  [PMID:29281883] [10.1021/acssynbio.7b00385]
12. Zhihong Wang, Chengzhang Wang, Changwei Zhang, Wenjun Li.  (2017)  Ultrasound-assisted enzyme catalyzed hydrolysis of olive waste and recovery of antioxidant phenolic compounds.  Innovative Food Science & Emerging Technologies,  44  (224).  [10.1016/j.ifset.2017.02.013]
13. Zhuang Yibin, Jiang Jingjie, Bi Huiping, Yin Hua, Liu Shaowei, Liu Tao.  (2016)  Synthesis of rosmarinic acid analogues in Escherichia coli.  BIOTECHNOLOGY LETTERS,  38  (4): (619-627).  [PMID:26667131] [10.1007/s10529-015-2011-1]
14. Yanhong BI, Zhaoyu WANG, Yanyong MAO, Shangyong ZHENG, Haijiang ZHANG, Hao SHI.  (2012)  Ionic Liquid Effects on the Activity of β-Glycosidase for the Synthesis of Salidroside in Co-solvent Systems.  CHINESE JOURNAL OF CATALYSIS,  33  (1161).  [10.1016/S1872-2067(11)60395-1]

参考文献

1. Chenchen Zhao, Yu Sha, Wei Zhuang, Yuan Rao, Jihang Zhang, Jinglan Wu, Tao Shen, Zhuotao Tan, Chenjie Zhu, Hongman Zhang, Hanjie Ying.  (2023)  Production of hydroxytyrosol from tyrosol via controllable oxidation with immobilized tyrosinase: A comparative study.  PROCESS BIOCHEMISTRY,  131  (144).  [10.1016/j.procbio.2023.06.017]
2. Tong Sun, Yan Liu, Ke Wang, Feiyu Duan, Lili Lu.  (2023)  Biotransformation of Tyrosol into a Novel Valuable α-Galactoside with Increased Solubility and Improved Anti-inflammatory Activities.  JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,  71  (25): (9836–9846).  [PMID:37319317] [10.1021/acs.jafc.3c02529]
3. Jue Chen, Qibin Cheng, Qianqian Ma, Yuqi Wu, Liwei Zhang.  (2023)  Salidroside synthesis via glycosylation by β-D-glucosidase immobilized on chitosan microspheres in deep eutectic solvents.  BIOCATALYSIS AND BIOTRANSFORMATION,  [10.1080/10242422.2023.2178308]
4. Fengxia Tang, Chuan Li, Xiaoran Yang, Jiandu Lei, Hongxia Chen, Changwei Zhang, Chengzhang Wang.  (2023)  Effect of Variety and Maturity Index on the Physicochemical Parameters Related to Virgin Olive Oil from Wudu (China).  Foods,  12  (1): (7).  [PMID:36613224] [10.3390/foods12010007]
5. Jinbin Liu, Kaipeng Wang, Mian Wang, Huaxiang Deng, Xiaodong Chen, Yueling Shang, Xiaochen Liu, Xiaohong Yu.  (2022)  Efficient whole cell biotransformation of tyrosol from L-tyrosine by engineered Escherichia coli.  ENZYME AND MICROBIAL TECHNOLOGY,  160  (110100).  [PMID:35872508] [10.1016/j.enzmictec.2022.110100]
6. Li Jiang, Yanling Xiong, Yu Tu, Wentong Zhang, Qiyun Zhang, Peng Nie, Xiaojun Yan, Hongning Liu, Ronghua Liu, Guoliang Xu.  (2022)  Elucidation of the Transport Mechanism of Puerarin and Gastrodin and Their Interaction on the Absorption in a Caco-2 Cell Monolayer Model.  MOLECULES,  27  (4): (1230).  [PMID:35209020] [10.3390/molecules27041230]
7. Xu Yu, Li Yu, Fei Ma, Peiwu Li.  (2021)  Quantification of phenolic compounds in vegetable oils by mixed-mode solid-phase extraction isotope chemical labeling coupled with UHPLC-MS/MS.  FOOD CHEMISTRY,  334  (127572).  [PMID:32721834] [10.1016/j.foodchem.2020.127572]
8. Wenjing Li, Congyong Sun, Wenwen Deng, Yingkun Liu, Michael Adu-Frimpong, Jiangnan Yu, Ximing Xu.  (2019)  Pharmacokinetic of gastrodigenin rhamnopyranoside from Moringa seeds in rodents.  FITOTERAPIA,  138  (104348).  [PMID:31470062] [10.1016/j.fitote.2019.104348]
9. Jiahong Han, Min Dai, Yan Zhao, Enbo Cai, Lianxue Zhang, Xiaohuan Jia, Nian Sun, Xuan Fei, Hui Shu.  (2020)  Compatibility effects of ginseng and Ligustrum lucidum Ait herb pair on hematopoietic recovery in mice with cyclophosphamide-induced myelosuppression and its material basis.  Journal of Ginseng Research,  44  (291).  [PMID:32148411] [10.1016/j.jgr.2019.01.001]
10. Zhihua Liao, Fei Qiu, Junlan Zeng, Li Gu, Bangjun Wang, Xiaozhong Lan, Min Chen.  (2018)  A Novel UDP-Glycosyltransferase of Rhodiola crenulata Converts Tyrosol to Specifically Produce Icariside D2.  Biomed Research International,  2018  (7970590).  [PMID:30027099] [10.1155/2018/7970590]
11. Xianglai Li, Zhenya Chen, Yifei Wu, Yajun Yan, Xinxiao Sun, Qipeng Yuan.  (2018)  Establishing an Artificial Pathway for Efficient Biosynthesis of Hydroxytyrosol.  ACS Synthetic Biology,  (2): (647–654).  [PMID:29281883] [10.1021/acssynbio.7b00385]
12. Zhihong Wang, Chengzhang Wang, Changwei Zhang, Wenjun Li.  (2017)  Ultrasound-assisted enzyme catalyzed hydrolysis of olive waste and recovery of antioxidant phenolic compounds.  Innovative Food Science & Emerging Technologies,  44  (224).  [10.1016/j.ifset.2017.02.013]
13. Zhuang Yibin, Jiang Jingjie, Bi Huiping, Yin Hua, Liu Shaowei, Liu Tao.  (2016)  Synthesis of rosmarinic acid analogues in Escherichia coli.  BIOTECHNOLOGY LETTERS,  38  (4): (619-627).  [PMID:26667131] [10.1007/s10529-015-2011-1]
14. Yanhong BI, Zhaoyu WANG, Yanyong MAO, Shangyong ZHENG, Haijiang ZHANG, Hao SHI.  (2012)  Ionic Liquid Effects on the Activity of β-Glycosidase for the Synthesis of Salidroside in Co-solvent Systems.  CHINESE JOURNAL OF CATALYSIS,  33  (1161).  [10.1016/S1872-2067(11)60395-1]

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