BioReagent 级 ，适用于对基线干扰要求严格的色谱和分析工作流程。
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在色谱分析、有机合成和交叉偶联反应领域已被 0 篇同行评审文献引用。
红细胞(Red blood cell，RBC)也称红血球，是血液中数量最多的一种血细胞，脊椎动物体内通过RBC运送氧气，RBC同时还具有免疫功能，在贫血检查中可通过蔗糖水溶血试验来检测红细胞膜的缺陷，尤其适用于检测阵发性睡眠性血红蛋白尿症(paroxysmal nocturnal hemoglobinuria, PNH)，该症为获得性红细胞膜缺陷引起的慢性血管内溶血，常在睡眠时加重，可伴发性血红蛋白尿和全血细胞减少。 该试剂盒是利用蔗糖溶液离子强度低，将患者血液置于37℃孵育后，可促进补体与红细胞膜的结合，使对补体敏感的红细胞膜上形成小孔，蔗糖水进入红细胞内引起红细胞膜破裂，发生溶血,主要用于检测人、动物血液的红细胞膜的缺陷，尤其用于鉴定阵发性睡眠性血红蛋白尿症。本产品仅用于科研领域，不适用于临床诊断或其他用途。
Red blood cells (RBCs), also known as erythrocytes, are the most abundant type of blood cell in the bloodstream. In vertebrates, RBCs are responsible for transporting oxygen throughout the body. RBCs also possess immune functions. In anemia testing, the sucrose water hemolysis test can be used to detect defects in the red blood cell membrane. This test is particularly suitable for diagnosing paroxysmal nocturnal hemoglobinuria (PNH), a condition characterized by chronic intravascular hemolysis caused by an acquired defect of the RBC membrane. Hemolysis often worsens during sleep and can be accompanied by paroxysmal hemoglobinuria and pancytopenia. This kit utilizes the low ionic strength of a sucrose solution. After incubating the patient's blood at 37°C, it promotes the binding of complement to the red blood cell membrane. This leads to the formation of pores on the membrane of complement-sensitive RBCs, allowing sucrose water to enter the cells, causing membrane rupture and hemolysis. It is primarily used to detect defects in the red blood cell membrane in human or animal blood, especially for identifying paroxysmal nocturnal hemoglobinuria. This product is intended for research purposes only and is not suitable for clinical diagnosis or other applications.
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