SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
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2020
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IF 3.232
Angxin Tong,Xiaojun Tang,Feng Zhang,Bin Wang
In this study, we mainly focused on predictable regularities of the red shift of ultraviolet spectra for β-phenylethylamine (PEA), NaCl and NaOH in aqueous solution. The absorption peaks of the UV spectra near 191 nm of NaCl, NaOH and PEA in aqueous solution moved in the direction of a red shift while the molar absorption coefficient at the peak increased regularly with the increasing solution concentration. These shifts were obtained for solutions with concentrations ranging from 3.68 to 1000 mmol/L for NaCl, from 0.762 to 2000 mmol/L for NaOH, and from 0.0515 to 8.91 mmol/L for PEA. The plots of the logarithm of the solution concentration for NaCl and PEA versus the absorbance at 191 nm and at the peak were linear, and the plots of the logarithm of the solution concentration for NaCl and PEA versus the wavelength at the peak (shifted from 191 nm) were also linear. In addition, the plots of the logarithm of the solution concentration for NaOH that ranged from 0.762 to 1.96 mmol/L versus the absorbance at 191 nm and at the peak were linear as well as the plots of the logarithm of the solution concentration for NaOH that ranged from 1.96 to 2000 mmol/L versus the wavelength at the peak. The slopes of the absorbance at 191 nm of PEA, NaCl and NaOH were somewhat similar to the absorbance at the peak separately, whereas the slopes of the wavelengths at the peak were different from them. Finally, in order to obtain the predictable regularity of the red shift of the UV spectrum for the mixture, 22 ternary mixtures were prepared. The results indicate that the inhibiting effect of hydroxide ions (OH-) caused the wavelength near 206 nm to remain unchanged when the solution concentration of NaOH in the mixture was more than 0.762 mmol/L.
研究领域:
化学
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光谱学
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分析化学
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DOI
高影响因子
Small
·
2020
·Vol. 16
·期 10
·1906707
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IF 11.459
Yunqing Kang,Joel Henzie,Huajun Gu,Jongbeom Na,Amanullah Fatehmulla,Belqes Saeed A. Shamsan,Abdullah M. Aldhafiri,W. Aslam Farooq,Yoshio Bando,Toru Asahi,Bo Jiang,Hexing Li,Yusuke Yamauchi
Selective hydrogenation of nitriles is an industrially relevant synthetic route for the preparation of primary amines. Amorphous metal–boron alloys have a tunable, glass-like structure that generates a high concentration of unsaturated metal surface atoms that serve as active sites in hydrogenation reactions. Here, a method to create nanoparticles composed of mesoporous 3D networks of amorphous nickel–boron (Ni-B) alloy is reported. The hydrogenation of benzyl cyanide to β-phenylethylamine is used as a model reaction to assess catalytic performance. The mesoporous Ni-B alloy spheres have a turnover frequency value of 11.6 h −1 , which outperforms non-porous Ni-B spheres with the same composition. The bottom-up synthesis of mesoporous transition metal–metalloid alloys expands the possible reactions that these metal architectures can perform while simultaneously incorporating more Earth-abundant catalysts.
研究领域:
材料科学
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催化
·
化工
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DOI
PubMed
高影响因子
ACS Omega
·
2023
·
IF 4.1
Angxin Tong,Xiaojun Tang,Haibin Liu,Honghu Gao,Xiaofei Kou,Qiang Zhang
The aim of this study is to enhance the classification performance of the back-propagation-artificial neural network (BP-ANN) algorithm for NaCl, NaOH, β-phenylethylamine (PEA), and their mixture, as well as to avoid the defects of the artificial bee colony (ABC) algorithm such as prematurity and local optimization. In this paper, a method that combined an improved adaptive artificial bee colony (IAABC) algorithm and BP-ANN algorithm was proposed. This method improved the ABC algorithm by adding an adaptive local search factor and mutation factor; meanwhile, it can enhance the abilities of the global optimization and local search of the ABC algorithm and avoid prematurity. The extracted score vectors of the principal component of the ultraviolet (UV) spectrum were used as the input variable of the BP-ANN algorithm. The IAABC algorithm was used to optimize the weight and threshold of the BP-ANN algorithm, and the iterative algorithm was repeated until the output accuracy was reached. The output variable was the classification results of NaCl, NaOH, PEA, and the mixture. Meanwhile, the proposed IAABC-BP-ANN algorithm was compared with discriminant analysis (DA), sigmaid-support vector machine (SVM), radial basis function-SVM (RBF-SVM), BP-ANN, and ABC-BP-ANN. Then, the above algorithms were used to classify NaCl, NaOH, PEA, and the mixture, respectively. In the experiment, four indicators, accuracy, recall, precision, and F-score, were used as the evaluation criteria. In addition, the regression equation parameters of the mixture for the testing set were obtained by BP-ANN, ABC-BP-ANN, and IAABC-BP-ANN models. All of the results showed that IAABC-BP-ANN exhibits better performance than other algorithms. Therefore, IAABC-BP-ANN combined with UV spectroscopy is a potential identification tool for the detection of NaCl, NaOH, PEA, and the mixture.
研究领域:
化学信息学
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分析化学
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DOI
PubMed
高影响因子
MICROCHEMICAL JOURNAL
·
2024
·
IF 4.9
Angxin Tong,Jinyang Zhu,Qiang Zhang,Shuai Tian,Xiaojun Tang,Hong Chen,Feng Zhang
This paper aimed at putting forward an approach integrating the improved clustering by fast search and find of density peaks ( I-CFSFDP) algorithm with Ultraviolet (UV) spectroscopy for identifying the species of NaCl, NaOH, β-phenylethylamine(PEA) and their mixtures. For solving the issue that the clustering precision of the CFSFDP algorithm relies on the density forecast of the dataset and the manually selection of the truncated distance d c . The idea of kernel density forecast was adopted to the I-CFSFDP algorithm. The I-CFSFDP algorithm can observe the clusters of arbitrary shapes and use an adaptive method to evaluate the truncated distance d c , thereby generating more accurate clusters and identifying the core points in the clusters effectively. The dimensions of the UV spectra was reduced with principal component analysis (PCA), and the results of PCA were invoked as the input of the I-CFSFDP algorithm. Meanwhile, the effect of PCA-I-CFSFDP was evaluated by recall, accuracy, F-Score and precision. Besides, the DBSCAN and PCA-CFSFDP algorithms were used to compare with the PCA-I-CFSFDP algorithm. All of the classification outcomes displayed that the PCA-I-CFSFDP algorithm has better performance than the DBSCAN and PCA-CFSFDP algorithms. Therefore, the PCA-I-CFSFDP algorithm integrated with UV spectroscopy is a simple, quick and credible identification approach for detecting PEA, NaCl, NaOH and the mixtures.
研究领域:
化学计量学
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分析化学
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DOI
高影响因子
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
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2021
·
IF 5.279
Nuo Duan,Mingqian Song,Weiyu Mi,Zhouping Wang,Shijia Wu
It is necessary to detect the biogenic amine (BA) content in food due to their toxicological effects and their role as an index of freshness for protein-rich foods. Aptamer-based techniques have the potential to provide alternative methods for sensitive and efficient monitoring of BAs. Herein, we described the selection and characterization of DNA aptamers for tyramine (TYR) and β-phenethylamine (PHE) using a one-pot coupled with separate selection strategy. During the selection process, melting curve analysis was developed to monitor the enrichment of the aptamer species, and a saturation of the selection was found at the 14th round. Based on the fluorescence assay, aptamers TYR-2 and PHE-2 showed high affinity to TYR and PHE with the dissociation constant values of 64.28 ± 10.4 and 71.64 ± 11.47 nM, respectively. The circular dichromatic and molecular docking technologies were employed for the preliminary binding mechanism analysis. The obtained aptamers TYR-2 and PHE-2 were used in a fluorescence method for the TYR and PHE determination with limits of detection of 0.34 and 0.39 ng/mL, respectively. In addition, the developed aptasensor was further applied to the TYR and PHE detection in pork and beer samples, and the recovery rate was between 95.6 and 104.2%. It was demonstrated that the selected aptamers had enormous potential as a molecular probe for the identification and determination of BAs.
研究领域:
食品科学
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分析化学
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分子生物学
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生物技术
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DOI
PubMed
高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
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2024
·
IF 8
Chen Chen,Ximo Wang,Xinyue Wang,Geoffrey I.N. Waterhouse,Ruiqiang Wang,Yufeng Sun,Zhixiang Xu
Surface-enhanced Raman spectroscopy (SERS) is a powerful tool for the detection of target analytes in foods, with the realization of “hot spots” between plasmonic metal nanoparticles (NPs) being critical for ultrasensitive detection. Herein, we proposed a new aptamer conformation-mediated SERS “hot spots” strategy. Au NPs were functionalized with strands of complementary DNA containing β-phenethylamine aptamers and the Raman reporter 4-mercaptobenzonitrile (4-MBN). This allowed DNA-driven self-assembly of an Au dumbbell dimer-based SERS aptasensor for the detection of the β-phenethylamine. After selective recognition of β-phenethylamine by the aptamer, the aptamer folded, bringing AuNPs in the dimers close together to create SERS “hot spots”. This produced an intense SERS signal in the “biologically silent” region for 4-MBN (2225 cm −1 ), the intensity of which increased linearly with the logarithm of the β-phenethylamine concentration. Under the optimized conditions, the linear range of SERS aptasensor was 10 −6 to 10 −2 mg L −1 , with a low limit of detection of 3.8 × 10 −7 mg L −1 . Further, the developed SERS aptasensor was successfully employed to determine the β-phenethylamine in a range of food samples, with the results being identical to those obtained using a high-performance liquid chromatography method.
研究领域:
分析化学
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食品科学
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纳米技术
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DOI
高影响因子
ADVANCED FUNCTIONAL MATERIALS
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2026
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IF 19.9
Yunlong Han,Jining Sun,Hao Jing,Suping Li,Qing Wang,Zhiyuan Zhang,Xuanyao Wang,Yayong Wang,Yongjie Guo,Zepeng Bao,Yi Zhang,Qianhao Xiao,Mengfan Lv,Ruonan Hao,Zhenqiang Shi,Yuanqian Zeng,Lei Zhang
Facilitating entropic elastic deformation is central to strengthening the mechanical resilience of 3D-printable elastomers. Despite extensive efforts that have focused on enhancing entropy-driven responses through regulating inter-chain interactions, the role of dangling chain conformational constraints in modulating elastic energy dissipation and mechanical reinforcement has remained largely overlooked. Herein, we challenge this prevailing convention by constraining polymer chain termini, thereby eliminating unbound ends and creating a fully connected molecular network. This end-constraint reweights the deformation response by suppressing slippage and enhancing entropic elasticity, unlocking a unique combination of high modulus, creep resistance, and toughness unattainable with conventional designs. By coupling terminal constraint and interchain physical crosslinking, 3D-printable elastomers achieve enhancement of over 571.1% and 388.2% in strength and toughness, while preserving printability and resilience. This work establishes chain-end engineering as a powerful principle for molecular design, opening avenues toward recyclable, durable, and high-performance soft materials for 3D printing, wearable electronics, and soft robotics.
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产品关联
DOI
高影响因子
MICROCHEMICAL JOURNAL
·
2026
·
IF 5.1
Yidan Zhang,Yuhua Lai,Yifei Ma,Lin Ge,Jinhua Liu
Since excess histamine (His) in seafood poses a significant health threat, the development of intelligent, on-site, and visual multimodal methods for detecting fish freshness has attracted widespread attention. In this study, we developed a Lewis base-induced paper-based chip coupled with smartphone RGB (Red Green Blue) recognition for the real-time colorimetric/fluorescent dual-mode detection of His in fish meat. The sensing mechanism was based on the catalytic role of His in rapidly forming a green fluorescent compound (GFC) from dopamine and 3-ethylamino-4-methylphenol. Interestingly, the introduction of 1% Tween (TW) 80 was found to significantly enhance the fluorescence signal and real-time stability of the system, achieving an exceptional detection limit of 16.67 nM for His. By immobilizing the GFC probe on Whatman 1 filter paper, a paper-based test strip for His was further developed. His quantification is achieved through RGB analysis with a smartphone, allowing visual and real-time assessment of fish meat freshness directly in the field. The developed sensor exhibits outstanding selectivity, stability, and sensitivity, and has been successfully applied to monitor His levels in fish meat samples (crucian, saury and golden pomfret) over time, providing a reliable means to prevent His poisoning. Therefore, this work presents a robust, low-cost, and user-friendly point-of-care testing platform that holds significant potential for applications in intelligent food monitoring and environmental sensing.
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产品关联
DOI
高影响因子
TALANTA
·
2026
·
IF 6.1
Hongyu Chen,Jiayi Guo,Xinrui Sun,Peipei Tian,Wenping Zhu,Manman Sun,Zengchen Liu,Qingfeng Li,Yahong Chen
A novel nano-sensing system was developed to enhance the selectivity and sensitivity of dopamine (DA) detection by integrating the strong cleavage effect of β-mercaptoethylamine (MEA) on trypsin-stabilized gold nanoflowers (Trypsin-AuNFs), the Schiff base/Michael addition reactions triggered by the bisphenol structure of DA, and the intramolecular hydrogen bonding within DA. Multiple characterizations including TEM, XPS and FT-IR confirmed that trypsin was anchored on the flower-shaped surface of AuNFs via Au-S bonds, endowing Trypsin-AuNFs with excellent structural stability. In addition, Trypsin-AuNFs can both effectively prevent the interference of biothiols ((cysteine (Cys), homocysteine (Hcy), glutathione (GSH)) in serum and have a strong interaction with MEA, resulting in the rapid cleavage of Trypsin-AuNFs. This is because MEA both induced the cleavage of Trypsin-AuNFs through the formation of Au-S bonds, and directly interacted with trypsin, disrupting its structure and accelerating the decomposition of Trypsin-AuNFs. These dual actions significantly enhanced the selectivity and sensitivity of the sensing system. It is worth noting that a detailed study of the interaction between MEA and trypsin and the optimal binding site through molecular docking was conducted for the first time. A detailed study of the impact of MEA on the spatial structure of trypsin was also conducted for the first time by using molecular dynamics. Moreover, the precise regulation of the Trypsin-AuNFs cleavage mechanism triggered by the DA-bisphenol structure through a Schiff base/Michael addition reaction was thoroughly investigated using UV-vis absorption spectroscopy (including functional group identification, steric hindrance comparison, and bisphenol regulation), 1 H NMR, zeta potential measurements, and TEM. This work provides a novel strategy for probing the interaction between MEA and proteins and offers a new perspective for improving the specificity of DA detection.
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DOI
PubMed
高影响因子
Small Methods
·
2026
·
IF 8.7
Tianshun Ding,Shi Feng,Hao Li,Zelong Zhang,Shengyang Tao
Chiral materials have broad applications in optics. Precise regulation of the chiral signal, however, remains highly challenging. Herein, a microfluidic strategy is proposed in which the cooperative action of dual driving forces regulates vortical flow inside droplets. The flow rate and interfacial tension are adjusted to induce ordered Marangoni convection and shear flow within microdroplets. Under these conditions, chiral signals are transmitted both within droplets and across the liquid-liquid interface. Tetrakis(4-sulfonatophenyl)porphyrin and phenethylamine are employed as a supramolecular co-assembly pair to probe the relation between vortex strength/distribution and chiral-signal transfer. Assemblies obtained under microdroplet vortex fields exhibit markedly enhanced and nearly mirror-image circular dichroism (CD) responses in comparison with those prepared under conventional magnetic stirring. These observations confirm that vortical flow efficiently promotes chiral amplification and enantioselective supramolecular assembly. Flow-field visualization by micro-particle image velocimetry (μ-PIV), combined with hydrodynamic analysis, reveals the formation mechanism and evolution of microvortices under the dual driving forces. Overall, this study demonstrates a practical approach to modulating supramolecular chiroptical signals via vortexes in confined environments.
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产品关联
DOI
PubMed
高影响因子
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
·
2026
·
IF 4.1
Wei Xiaolan,Wang Peng,Li Linjin,Luo Zhu,Ye Xinyuan,Long Jiujiang,Liu Xianghui
Biogenic amines (BAs), primarily formed through the microbial degradation of proteins, are important markers indicating food fermentation and spoilage. On the demand of on-site monitoring of food quality and safety, electrochemical and optical sensors have been developed, focusing on the detection of the total volatile amines or a specific amine. However, the multiplex detection of BAs with high accuracy and sensitivity still remains a major challenge. The sensor array strategy that mimics the biological olfactory sense provides an effective and powerful route to achieve multiplex detection of BAs. Herein, (metallo)porphyrin-based hydrogen-bonded organic frameworks embedded with silver nanoparticles were prepared and used as receptors to construct the surface-enhanced Raman scattering (SERS) sensor array, leveraging the multiple chemical interactions and the sharp Raman signals of (metallo)porphyrins, and the porous and flexible structure of the supramolecular frameworks. This SERS sensor array demonstrated a successful discrimination of ten BAs, an accurate quantitation of three BAs, and a successful simultaneous determination of three BAs in pork samples. Using the total volatile basic nitrogen as a spoilage label, the platform achieved over 90% accuracies in freshness discriminations for pork, beef, and chicken samples. In comparison with the existing detection methods, the proposed SERS sensor array strategy based on porphyrin- and metalloporphyrin-based hydrogen-bonded organic frameworks exhibits operational simplicity, rapid response, high sensitivity, as well as multiplex detection capability. Thus, it demonstrates a significant practical potential for applications in the production line and the supply chain of foods.
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DOI
高影响因子
REACTIVE & FUNCTIONAL POLYMERS
·
2025
·
IF 5.1
Chunyu Song,Jiahao Huang,Chenglong Qiu,Yong Yang
Temperature monitoring is essential for many natural and engineering processes in our daily life. Reversible and irreversible temperature sensors for different applications or environments have been devised to accommodate these processes. In this study, two polydiacetylenes (PDA-1 and PDA-2) functionalized with amide groups are prepared by topochemical polymerization, which exhibit reversible and irreversible thermochromic behavior at different temperatures. The thermochromic properties of these PDAs are evaluated by UV–vis absorption spectrum. Both samples can undergo multi-step thermochromic processes, which turn red at 80 and 90 °C, respectively. Their thermal stabilities are characterized by thermogravimetric analyses, which demonstrate that both PDAs are sufficiently stable when used up to 200 °C. The changes in the unsaturated structure before and after heating the resulting PDAs are revealed by Raman spectroscopy. In-situ FTIR spectroscopy captures the dynamic changes of molecular bonds and conjugated structures under thermal stimulation. Compared with PDA-1, strong hydrogen-bonding networks and aromatic interactions in headgroup provide PDA-2 with the capability of recovering its initial molecular organization and average π-electron conjugation length upon removal of thermal stimuli. PDAs present aggregated sheet-like structure before and after heating upon 100 °C. XRD results reveal that the blue-to-red color transition originated from the slight increase of the d-spacing value of the macromolecular backbones. The CR value of PDA-2 reaches 0.65 at 100 °C, indicating superior color transfer performance. Once cooled to 20 °C, the CR value sharply drops back to its initial level, demonstrating that its thermochromic reversibility is quite high. In particular, PDA-2 presents a reversible thermochromic feature upon heating at 100 °C, making it an efficient and reusable temperature-sensing material.
研究领域:
材料科学
·
化学
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产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）