FOOD CHEMISTRY
·
2025
·
IF 9.8
Wangfei Yu,Guannan Wang,Huizhi Chen,Honglei Mu,Ben Niu,Yanchao Han,Lishu Wang,Hangjun Chen,Haiyan Gao
To address the poor hydrolytic stability of CD-MOF in food applications, CD-MOF loaded with thymol (TCDM) was prepared and filled into a pectin (PEC)/sodium alginate (SA) substrate with the aid of zein to obtain a thymol-CD-MOF/zein-PEC-SA (TCDM/ZPS) polymer film. Characterization revealed that zein-PEC/SA (ZPS) protected TCDM by forming amphiphilic microspheres. TCDM was able to exist stably in the hydrophilic polysaccharide substrate and achieve a long-term slow release over 336 h. Besides, environmental humidity could also be used as a switch for regulating the thymol release rate, which was consistent with the first-order release model (R 2 > 0.99). TCDM and TCDM/ZPS showed excellent antimicrobial effects against E. coli , S. aureus , and B. cinerea , the most common fungi in plant-based foods. The preservation experiment maintained the quality of strawberry and Agaricus bisporus mushroom. This strategy holds the potential to broaden the application scope and enhance the utility of CD-MOF in food preservation.
研究领域:
食品科学
·
材料科学
·
微生物学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
FOOD CHEMISTRY
·
2025
·
IF 9.8
Xuan Wang,Xu Meng,Tao Liang,Jiachun Song,Kamal Eldin Afaf,Hong Duan,Lingyan Zheng,Gang Chen
γ-Cyclodextrin (γ-CD) is one of the most widely used materials for encapsulating hydrophobic functional molecules due to its distinctive structural features, especially an internal hydrophobic cavity surrounded by external hydrophilic surface. However, its limited loading capacity, adsorption efficiency, and poor stability hinder its broader applications. To address this issue, γ-cyclodextrin-based metal-organic frameworks (γ-CD-MOFs) was formed by anchoring potassium ions with γ-CD through hydrothermal self-assembly. After loading different hydrophobic small molecule active substances, a multifunctional composite coating was prepared by embedding them into the chitosan (CS) matrix. The release kinetic model analysis confirmed that the release behavior of Cinnamaldehyde (Cia), 2-methoxycinamaldehyde (2-MCA), and Curcumin (Cur) from γ-CD-MOFs conformed to the Ritger-Peppas equation. Compared with CS, CS/γ-CD-MOF@Cia has a strong inhibitory effect on E. coli O157: H7 and S. aureus . Sprayed on green grapes, the shelf life is extended to 21 days. CS/γ-CD-MOF@2-MCA can significantly reduce the spoilage of milk caused by photooxidation. Furthermore, compared with CS, the oxidation and browning of banana peels were effectively delayed by CS/γ-CD-MOF@Cur, and complete blackening is not observed even after 11 days of storage. By combining the advantages of chitosan and γ-CD-MOF, the active molecules with different functions were encapsulated on the platform of γ-CD-MOF to achieve antibacterial, light-blocking, and antioxidant effects on food. The novel functional coating materials presented in this work offer a promising approach to effectively prolonging the shelf life of fresh foods products.
研究领域:
食品科学与技术
·
材料科学
·
纳米技术
·
活性包装
·
控释
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Nanoscale Advances
·
2022
·Vol. 4
·期 9
·2171-2179
·
IF 5.598
Dawei Xu,Xuhui Li,Tingting Zheng,Ruixue Zhao,Pengyu Zhang,Kai Li,Zhongfeng Li,Lirong Zheng,Xia Zuo
Here, a series of Fe/N/C catalysts with different proportions and pyrolysis temperatures are prepared by co-pyrolysis of melamine with a γ-cyclodextrin metal–organic framework (γ-CD-MOF) containing iron(II) phthalocyanine (FePc). Due to the restriction effect of the host and guest at the molecular level, γ-CD-MOF can effectively avoid the π–π stacking of FePc and restrain the agglomeration of Fe atoms during pyrolysis. The phases and structures of the catalysts are characterized, which proves that the obtained catalyst has a three-dimensional porous and internal cavity structure with abundant surface area (1055.317 m2 g−1) and Fe is atomically dispersed in nitrogen-doped carbon. The onset potential (0.988 V vs. RHE) and half-wave potential (0.846 V vs. RHE) of FePc@CD/M (1 : 20)-1000 are superior to those of a commercial 20% Pt/C catalyst. FePc@CD/M (1 : 20)-1000 also exhibits an approximately four-electron (3.84) transfer process, good stability and excellent methanol tolerance.
研究领域:
材料科学
·
催化化学
✓ 已验证
DOI
高影响因子
FOOD CONTROL
·
2024
·
IF 5.6
Shuqi Zhang,Jing Yi,Zhilong Zhang,Xuanxuan Yuan,Zhongguo Shan,Haihua Wang
The growing concerns over food contamination caused by microorganisms, coupled with the worsening environmental impact of petroleum-based plastics have drawn significant attention to eco-friendly materials in food packaging. Herein, cyclodextrin-metal-organic framework (CD-MOF) was prepared as promising nanocarrier for the natural product gallic acid (GA). Then, the prepared material (GA@CD-MOF) was incorporated into zein matrix to obtain Zein-GA@CD-MOF films. Further studies showed that the composite films possessed great potential for food packaging, offering excellent UV-light blocking, water resistance , and mechanical properties. Notably, Zein-GA@CD-MOF films demonstrated superior antimicrobial activity (44.56%–77.97% against Escherichia coli O157:H7 and 28.36%–59.49% against Salmonella enterica ) and sustained antioxidant properties for 100 days, which correlated with the sustainable release effect of GA. Furthermore, the exceptional biosafety of GA@CD-MOF has been confirmed through cytotoxicity and hemolysis assays. Pork preservation experiments illustrated that the obtained films could retard protein degradation, microorganism growth, and lipid oxidation, extending the shelf-life by 9 days at 4 °C. These findings suggest that Zein-GA@CD-MOF films has promising application prospects in pork preservation packaging.
研究领域:
食品科学
·
材料科学
·
生物技术
·
环境科学
✓ 已验证
产品关联
DOI
高影响因子
FOOD CHEMISTRY
·
2026
·
IF 10.4
Mingsha Jie,Amei Zhu,Zhendong Liu,Junguang Li,Zeyu Xu,Xiaoyue Yue,Yanhong Bai
γ-CD-MOF@Eu-MOF flower-like probe synthesized for sensitive sulfonamides detection. • Paper-based sensor enables portable, visual on-site testing via smartphone imaging. • Machine learning algorithm boosts detection speed and reliability for quantitation. • The detection limit of the γ-CD-MOF@Eu-MOF for SAs is as low as 25.5 nmol/L. The protection of human health and the guarantee of food safety necessitate rapid and precise identification of sulfonamides (SAs) residues in food. Herein, we propose a fluorescence sensor based on γ-CD-MOF@Eu-MOF, which is used for quantitative and visual detection of SAs. The γ-CD-MOF@Eu-MOF exhibits high selectivity toward SAs, with detection limits for sulfamerazine (SMR), sulfamethazine (SM 2 ), and sulfamethoxydiazine (SMD) as low as 25.5 nmol/L, 36.7 nmol/L, and 39.8 nmol/L, respectively. The fluorescent probes were immobilized on paper substrates to construct a paper-based sensor, which was combined with a smartphone-assisted machine learning algorithm to enable high-throughput, intelligent, and rapid detection of SAs. After optimizing the constructed prediction model, the coefficient of determination can reach 0.99, indicating the accuracy and applicability of the model. Overall, this sensor exhibits excellent stability, sensitivity, and specificity, providing a practical approach for the intelligent, rapid, and high-throughput on-site visual detection of SAs. Download: Download high-res image (163KB) Download: Download full-size image
✓ 已验证
DOI
PubMed
高影响因子
DRUG DELIVERY
·
2021
·
IF 6.419
Congcong Li,Chaoxi Chen,Yucai Wei,Min Tan,Shuo Zhai,Juebo Zhao,Lu Wang,Tao Dai
It is urgently needed to develop novel adjuvants for improving the safety and efficacy of vaccines. Metal-organic frameworks (MOFs), with high surface area, play an important role in drug delivery. With perfect biocompatibility and green preparation process, the γ-cyclodextrin metal-organic framework (γ-CD-MOF) fabricated with cyclodextrin and potassium suitable for antigen delivery. In this study, we modified γ-CD-MOF with span-85 to fabricate the SP-γ-CD-MOF as animal vaccine adjuvants. The ovalbumin (OVA) as the model antigen was encapsulated into particles to investigate the immune response. SP-γ-CD-MOF displayed excellent biocompatibility in vitro and in vivo. After immunization, SP-γ-CD-MOF loaded with OVA could induce high antigen-specific IgG titers and cytokine secretion. Meanwhile, SP-γ-CD-MOF also significantly improved the proliferation of spleen cells and activated and matured the bone marrow dendritic cells (BMDCs). The study showed the potential of SP-γ-CD-MOF in vaccine adjuvants and provided a novel idea for the development of vaccine adjuvants.
研究领域:
药学
·
免疫学
·
疫苗学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）