查找使用阿拉丁产品的科研文献

Functional evaluation of laminarin butyl esters: Antioxidant, skin-whitening, and anti-wrinkle properties

Kit-Leong Cheong,Keying Liu,Suresh Veeraperumal,Gowsika Jaikumar,Sathuvan Malairaj,Xiaofei Liu,Xuejing Jia,Peiying Zheng,Hengyi Jiang,Ruixu Cai,Saiyi Zhong,Udayakumar Veerabagu

Laminarin, a polysaccharide derived from brown algae, has gained attention for its potential biological activities. However, its application in cosmetic formulations is limited due to its functional properties. To enhance its bioavailability and performance, laminarin was modified through esterification to form laminarin butyl esters (LBE). This study aimed to evaluate the antioxidant, skin-whitening, and anti-wrinkle properties of LBE and assess its potential as a novel ingredient in skincare products. Antioxidant activity was evaluated using in vitro assays, including DPPH and ABTS radical scavenging, both of which demonstrated significant free radical neutralizing capacity. Skin-whitening and anti-wrinkle activities were assessed by measuring the inhibition of tyrosinase and elastase. The results indicated that LBE exhibited significantly higher inhibitory effects than native laminarin, with tyrosinase inhibition reaching 26.7 % (compared to 4.7 % for laminarin) and elastase inhibition at 45.8 % (versus 18.5 % for laminarin). Additionally, LBE showed stronger anti-glycation activity, as it effectively inhibited Amadori products, dicarbonyl compounds, and advanced glycation end-products. These findings provide valuable insights into the modification of laminarin and its potential application in cosmetics, offering a foundation for the development of more effective, bioactive ingredients in the beauty industry.