INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
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2025
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IF 3.9
Hongfei Mei,Jinsong Peng,Haiyan Song,Chunxia Chen
Photocatalytic H2O2 production in seawater offers a novel and sustainable route for the substitution of freshwater consumption. However, this strategy is limited by the complexity and cost resulting from electron–proton donors and pure O2 dependency. Simultaneously, adsorption, a frequently used method to treat radionuclide wastewater, latently causes issues of adsorbent-caused waste and pollution. In this work, we designed a sustainable system based on recycling MXene Ti3C2 adsorbent after radioactive cesium (Cs+) uptake and further used it in photocatalytic H2O2 production from seawater. The adsorptive performance and behavior of Ti3C2 were evaluated for model nuclear wastewater with different Cs+ concentrations. Cs+ was uniformly adsorbed on the layer surface of Ti3C2 and promoted the delamination of Ti3C2. Cs+ uptake also improved e––h+ pair separation and photogenerated electron transfer on the Ti3C2 matrix. Without using an organic electron–proton donor and pure O2, Ti3C2 adsorbed Cs+ achieved 892.43 μmol·g–1·h–1 H2O2 productivity in real seawater, which was 1.84 times higher than that over pristine Ti3C2. It also obtained 12.44% apparent quantum yield (AQY) at 550 nm, and 6 cycles of reusability. Enhancement in photocatalytic performance was attributed to the regulation of the bandgap of Ti3C2 by the adsorbed Cs+ from 1.51 eV to a semiconductor range of 2.00 eV. Further, the conduction band (CB) of Ti3C2 was shifted to a more negative potential, facilitating the two-electron reduction of O2 to generate more H2O2. This study opened avenues for the sustainable use of spent adsorbents and resolved freshwater reliance.
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ACS Applied Materials & Interfaces
·
2025
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IF 8.2
Li Wang,Fan Yang,Jie Gong,Weiwei Chen,Yinbang Zheng,Xi Chen,Weiqing Hu,Yi Li,Ke Yang,Zefeng Wang,Dinggeng He,Luo Hai
Bacterial infections, particularly those caused by multidrug-resistant (MDR) bacteria, pose a serious global health threat. The limited efficacy of traditional antibiotic drugs against MDR strains and the slow development of antibiotics necessitate the exploration of alternative therapeutic strategies. Acid-degradable metallic peroxide has emerged as a promising solution, exhibiting broad-spectrum antimicrobial activity with a reduced risk of resistance development. In this study, we have constructed an acid-responsive bimetallic peroxide nanocomposite (ZCS@M@HA) for the treatment of wound infections involving methicillin-resistant Staphylococcus aureus (MRSA). In our design, the copper-doped zinc peroxide (ZC) nanoparticles are prepared and coated with mesoporous silica to obtain core–shell structured ZC@M, which is subsequently loaded with S-nitroso-N-acetylpenicillamine (SNAP) acting as a nitric oxide (NO) donor and capped with sodium hyaluronate (HA) to prevent premature SNAP release. In the acidic microenvironment of infectious sites, ZCS@M@HA releases Zn2+, Cu2+, and H2O2, and the former disrupts bacterial energy metabolism by impairing the electron transport chain. Meanwhile, self-supplied H2O2 and Cu2+ perform a Fenton-like reaction to generate highly toxic hydroxyl radicals (•OH) for damaging bacterial membranes. Moreover, Cu2+ depletes intracellular glutathione (GSH) to augment the oxidative stress. Furthermore, NO released from SNAP triggered by Cu2+ and GSH accelerates wound healing by promoting collagen deposition, tissue regeneration, and vascularization. In vivo assays demonstrate the high MRSA inhibition efficacy of ZCS@M@HA with optimal wound healing. The proposed acid-responsive ZCS@M@HA with multi-bactericidal modalities offers an effective approach to fight MDR bacteria and presents a promising strategy for treating wound infections.
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ANALYTICAL CHEMISTRY
·
2025
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IF 6.7
Yajuan Yan,Jialian Ding,Wenxuan Fu,Lurong Ding,Wei Hu,Guangzhong Ma,Bin Su
Immunotherapy using activated T cells as the weapon for controlling and eliminating tumor cells represents a promising therapeutic strategy for cancer treatment, in which accurate detection of T cell activation is critical for evaluating the immunotherapy efficacy. Activated T cells upregulate specific plasma membrane biomarkers, such as CD69, that can act as an indicator of activation status. In this work, we report a novel strategy of assessing T cell activation by electrochemiluminescence (ECL) imaging of CD69 expression on the plasma membrane. Mesoporous silica nanoparticles functionalized by polyethylenimine (PEI-SiO2) were prepared as both “nanocoreactant” and “nanoreactor” to remarkably enhance the ECL reaction through a dual-pathway scheme, in which both the catalytic route and the low-oxidation-potential route contribute to produce an enhanced ECL signal. Based on this strategy, subsequent conjugation of PEI-SiO2 with anti-CD69 antibodies allowed us to detect individual CD69 proteins by single-molecule ECL imaging, visualize their spatial distribution on the plasma membrane of activated T cell, and reveal their expression dynamics. The results establish a novel dark-field imaging strategy for assessing T cell activation, offering a low-background tool for investigating immune cell dynamics and immunotherapy efficacy through single-cell-level analysis of key biomarkers.
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Polymers
·
2025
·Vol. 17
·期 21
·2814
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IF 4.9
Hongyu Feng,Haijing Ma,Tian Jing,Bohan Zhai,Yanyan Dong,Shaohua Jiang,Xiaoshuai Han
Flexible polyurethane foam (FPUF) is widely used in buffer protection, biomedical, and wearable fields due to its light weight, high resilience, and adjustable mechanical properties. However, the traditional water foaming system is often accompanied by bottleneck problems such as cyclic fatigue attenuation, insufficient thermal stability, and surface hydrophilicity while achieving low density. In this study, a dense Si-O-Si cross-linked layer was in situ constructed on the surface of the foam by systematically regulating the water content of the foaming agent (1.5~2.5 wt%) and coupling with methyltrimethoxysilane (MTMS) chemical vapor deposition. Experiments show that the foam foamed with 2 wt% water content still maintains 0.0466 MPa compressive strength and 0.0532 MPa compressive modulus (modulus loss is only 16.6%) after 500 cycles of compression at 90% strain after MTMS deposition. MTMS modification drives the surface wettability to change from hydrophilic (70.4°) to hydrophobic (128.7°), and significantly improves thermal stability (the carbon residue rate at 800 °C increased to 25.5%, an increase of 59.4%). This study not only improves the resilience, but also endows the FPUF surface with hydrophobicity and thermal protection ability, which provides the feasibility for its wide application.
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APPLIED CATALYSIS A-GENERAL
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2025
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IF 4.8
Xiaolong Tang,Shuxin Zhang,Shuyuan Yu,Yanbin Jiang,Changlin Yu
The photocatalytic production of H 2 O 2 from H 2 O and O 2 via solar light-driven is a low-cost, safe, and environmentally friendly route for H 2 O 2 production, but the high carrier recombination rate and insufficient active sites in the photocatalytic process greatly limit the efficiency of H 2 O 2 generation. Here, we combined both vacancy modification and heterojunction engineering strategies to modify In 2 S 3 , successfully constructing In 2 S 3 /Ni Schottky junctions (SvIS/Ni) with rich S vacancies via a two-step calcination-photo-deposition method. The introduction of rich S vacancies and the formation of Ni Schottky both enhance the absorption of visible light by In 2 S 3 and substantially improve its carrier separation efficiency. Notably, we also found that SvIS/Ni is capable of realizing multi-channel reaction pathways for oxygen reduction and water oxidation to promote the H 2 O 2 generation. Benefiting from the above advantages, the H 2 O 2 yield of SvIS/Ni in the pure water system under visible light irradiation could reach 1146.6 µmol·g −1 h −1 , which is 13.4 times that of pure In 2 S 3 , and the apparent quantum yield (AQY) at 400 nm can reach 3.58 %. This study provides a novel idea for designing highly efficient photocatalysts by combining defect engineering and heterojunction modification strategies.
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Journal of Energy Storage
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2025
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IF 9.8
Jianchi Wang,Xusheng Cheng,Liwei Wang
All-soluble all-iron redox flow batteries (RFBs) are among the most promising energy storage technologies due to their low cost, dendrite-free operation, and decoupled capacity and power. In particular, the Fe(TEA) 3+/2+ redox couple has attracted significant attention owing to its appropriate redox potential, fast kinetics, and excellent reversibility. However, the instability of Fe(TEA) chelates, caused by the competitive adsorption of free TEA ligands, remains a major challenge that limits cycling stability and energy efficiency. Herein, we propose a green and efficient strategy to fabricate Nitrogen-doped graphite felt (N@GF) as the anode for the Fe(TEA)-based system and identify the optimal doping concentration. The abundant nitrogen-containing functional groups endow the felt with synergistic electronic modulation and surface coordination capabilities, enabling selective Fe(TEA) complexation while suppressing the undesired adsorption of free TEA ligands by occupying the limited active sites. This tailored interfacial regulation stabilizes Fe(TEA) complexes and enhances charge-transfer efficiency. As a result, the battery employing 5 %N@GF as the anode operates stably for over 950 deep charge–discharge cycles (near 260 h) at 80 mA cm −2 , exhibits significantly reduced polarization compared to pristine GF, achieves a peak energy efficiency above 78 % and a capacity utilization exceeding 83 %. This work offers an eco-friendly and effective material design strategy for improving both the energy efficiency and cycle life of all-soluble all-iron redox flow batteries.
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APPLIED SURFACE SCIENCE
·
2025
·
IF 6.9
Wenbin Ruan,Jianli Chen,Shijian Zhang,Xiuxiu Huang,Xiang Li,Shuangshuang Huai,Congliang Cheng,Mingxuan Qu,Hewen Liu,Xiufang Wang,Ping Li
Here, the Bi 24 O 31 Br 10 -based composite photocatalysts modified by bimetallic Bi and Mo nanoparticles (NPs) are designed and prepared (Bi-Mo-Bi 24 O 31 Br 10 ). 2D ultra-thin Bi 24 O 31 Br 10 nanosheets with suitable band gap and good chemical and optical stability are selected as the main catalyst to drive N 2 fixation by generating hot carriers. The Bi NPs in the Bi 24 O 31 Br 10 nanosheets serves as a buffer tank for electrons to improve the efficiency of electron transfer. Meanwhile, the Mo NPs serve as catalytic centers for N 2 adsorption and activation, working synergistically to enhance the overall reaction efficiency. Resulting from semiconductor-to-metal −to-metal electron transfer path and the Mo metal adsorption and activation mechanism, the nitrogen fixation rate of the Bi-Mo-Bi 24 O 31 Br 10 photocatalyst is as high as 191.2 μmol g −1 h −1 , and it is 7.2 times compared to pure Bi 24 O 31 Br 10 . This work creates a novel framework for the rational design of highly efficient visible-light-responsive nitrogen fixation catalysts.
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APPLIED CATALYSIS A-GENERAL
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2025
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IF 4.8
Xiaoling Chen,Yujuan Lu,Hui Li,Hongwei Mi,Guoqiang Zhang
Non-radiative recombination is the key bottleneck to overcome the charge separation problem. Here, we use poly(heptazine imide) (PHI) as a model photocatalyst to investigate the effect of internal electric field (IEF) on non-radiative recombination. Introducing electron-deficient boron atoms into the PHI structure leads to an uneven distribution of in-plane charges, spontaneously polarizing the formation of an IEF. This enhanced IEF can exert a force on the carrier in the opposite direction of the Coulomb force, thus effectively weakening the carrier trapping by the charged defect, thereby suppressing the non-radiative recombination. This is the first systematic research of suppressing non-radiative recombination by IEF in photocatalysis, which provides guiding strategies for addressing the bottleneck of charge separation in photocatalysis.
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CHEMICAL ENGINEERING JOURNAL
·
2025
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IF 13.2
Yaotian Chang,Tongshuai Wang,Lipeng Xu,Xiaopan Liu,Qingyu Wang,Jiaru Hui,Yuhua Shi,Yong Zhang,Yaming Shan
Current subunit vaccines targeting infectious diseases, such as AIDS, face significant challenges in effectively activating immune responses, particularly in inducing broadly neutralizing antibodies (bNAbs). Nanoparticles (NPs) offer an effective delivery platform for subunit vaccines, providing distinct advantages including antigen stabilization and targeted delivery. In this study, we developed an innovative multi-scale NP delivery system using amino-modified mesoporous silica NPs (MSNs) with a 13 nm pore size. This system was designed to load and present HIV-1 native-like envelope (Env) proteins, UFO-BG, which were pre-assembled on ferritin nanocages (referred to as UFO-BG-FR). The UFO-BG-FR@MSN enabled highly stable and dense array presentation of Env proteins, while effectively exposing their neutralizing epitopes. Compared to free Env protein UFO-BG, UFO-BG-FR@MSN enhanced multivalent interactions with antigen-presenting cells, thereby facilitating the antigen uptake and activation effects of lymph node dendritic cells and B cells. This also promoted the robust activation of follicular helper T cells and germinal center B cells in lymph nodes. In guinea pigs, UFO-BG-FR@MSN induced broader and more sustained neutralizing antibody (NAb) responses, targeting multiple bNAb epitopes on the Env. These results highlight the importance of multi-scale NPs in addressing the insufficient immunogenicity of subunit vaccines. Our findings offer a promising delivery strategy for designing vaccines against infectious diseases caused by highly mutated viruses.
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CHINESE JOURNAL OF POLYMER SCIENCE
·
2025
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IF 4
Liu He-Chen,Zhou Xin-Xin,Zhou Song-Song,Zou Ying,Wang Yu-Li,Li Xiang-Qing
The most widely used bisphenol A-type epoxy resin (DGEBA) in electrical engineering demonstrates excellent mechanical and electrical properties. However, the insoluble and infusible characteristics of cured DGEBA make it difficult to efficiently degrade and recycle decommissioned electrical equipment. In this study, a degradable itaconic acid-based epoxy resin incorporating dynamic covalent bonds was prepared through the integration of ester bonds and disulfide bonds, with itaconic acid as the precursor. The covalent bonding effects on the mechanical, thermal, electrical, and degradation characteristics were systematically evaluated. The experimental results revealed that the introduction of dynamic ester bonds enhanced the mechanical properties and thermal stability of the resin system, achieving a flexural strength of 141.57 MPa and an initial decomposition temperature T 5% of up to 344.9 °C. The resin system containing dynamic disulfide bonds exhibited a dielectric breakdown strength of 41.11 kV/mm. Simultaneously, the incorporation of disulfide bonds endowed the epoxy resin with remarkable degradability, enabling complete dissolution within 1.5 h at 90 °C in a mixed solution of dithiothreitol (DTT) and N -methylpyrrolidone (NMP). This research provides a valuable reference for the application of itaconic acid-based vitrimer with dynamic covalent bonds in electrical materials, contributing to the development and utilization of environmentally friendly electrical equipment.
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CHINESE JOURNAL OF POLYMER SCIENCE
·
2025
·
IF 4
Liu He-Chen,Li Xiang-Qing,Zhou Xin-Xin,Tian Huai-Qing
The introduction of dynamic covalent bonds into the structure of epoxy resins can improve the degradation performance of the materials. But to a certain extent, it will affect the insulating properties of the resin, and how to balance the insulating properties and degradation performance has become an urgent problem. In this paper, the effects of different catalysts on the thermal-force-electrical properties of sorbitol-based resins were systematically investigated based on the dynamic ester bonding to construct the resin crosslinking network, and the biobased sorbitol glycidyl ether was used as the resin matrix. The experiments show that the resin system catalyzed by triethanolamine (TEOA) exhibits excellent comprehensive performance, which combines good thermal stability and mechanical properties with excellent electrical properties (breakdown field strength of 44.21 kV/mm and dielectric loss factor of 0.29%). In addition, chemical degradation tests were conducted on the resin systems with different catalysts, and the experiments showed that the produced resins could be degraded in benzyl alcohol and exhibited good degradation performance. This study provides a theoretical basis and technical path for the development of new bio-based electrical insulating materials with both high insulation and degradation properties, which is conducive to the popularization and application of bio-based resins in the field of electrical equipment.
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PEST MANAGEMENT SCIENCE
·
2025
·
IF 3.8
Haodong Wang,Yangping Sun,Qi Liu,Mengci Ma,Long Hu,Gehong Wei,Chun Chen
BACKGROUND Soybean production is severely affected by the soil-borne phytopathogenic, Fusarium oxysporum , which causes root rot disease. Artificial nanoplatforms have attracted attention as a sustainable strategy to promote crop growth and protection. RESULTS In this study, mesoporous silica nanoparticles (MSNs) loaded with lipopeptide (Lip), referred to as Lip@MSNs, were synthesized with a diameter of approximately 50 nm and a Lip loading capacity of 22.40 wt%. Lip@MSNs demonstrated potent antifungal activity against F. oxysporum , inducing cell membrane disruption, permeability alterations, nuclear damage, and subsequent cell death. Pot experiment showed that Lip@MSNs significantly reduced the severity of soybean root rot disease by 43.10% while enhancing plant growth and root development. Metabolomic analysis revealed that Lip@MSNs modulated critical metabolic pathways, including zeatin and pyrimidine metabolic pathways in roots. Furthermore, Lip@MSNs recruited beneficial endophytic bacteria, such as antagonistic genera ( Sphingomonas , Variovorax , and Streptomyces ) and growth-promoting genera ( Rhizobium , Ensifer , and Nocardioides ). Correlation analysis highlighted the role of these bacteria in nitrogen fixation and phytohormone production (e.g., trans -zeatin), contributing to reduced root rot disease severity and improved plant health. CONCLUSION These findings demonstrate that the silicon-based delivery system could serve as an effectively tool to control soil-borne phytopathogenic diseases and promote the development of sustainable agriculture. © 2025 Society of Chemical Industry.
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