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FOOD CHEMISTRY · 2025 · IF 9.8

Intelligent double-layer pads containing blueberry anthocyanins/citric acid/tricolor lake for chilled pork real-time freshness monitoring

Junna Sun,Ye Zhang,Rui Liu,Jian Du,Qingdai Liu,Tianxin Wang,Yuan Wang,Hao Wang

In this paper, an intelligent pH-sensitive pad was well designed using blueberry anthocyanin (BA) mixed with citric acid (CA) and yellow lake (Y), as composite indicator with significant color change (ΔE) from pink to yellow to green at pH 6.0–7.0 under tricolor principle. The double-layer poly(vinyl alcohol)/glycerol/gelatin (PGG)-CA/PGG-CA-BA-Y pad exhibited an excellent colorimetric pH/NH 3 -response, water-absorption ability, mechanical properties and preservation performance. Applied into the freshness monitor of chilled pork, the pad color change was detected from red (fresh) to orange (semi-fresh) and then to green (spoiled) by both naked eye visually and mobile APP rapidly, as the correlation coefficients (R 2 ) of ΔE and S RGB significantly correlated with pH (0.99 and 0.98) and TVB-N (0.96 and 0.96), respectively. In summary, intelligent pH-sensitive double-layer hydrogel pads could preciously monitor food freshness and prevent the spoilage, by improving anthocyanin stability and increase the sensitivity of color in response to a narrow pH range.

研究领域: 食品科学 · 生物化学
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CELL · 2025 · IF 42.5

Near-infrared spatiotemporal color vision in humans enabled by upconversion contact lenses

Yuqian Ma,Yunuo Chen,Sheng Wang,Zi-Han Chen,Yuanwei Zhang,Ling Huang,Xinxin Zhang,Fei Yin,Yunxuan Wang,Mingzhu Yang,Zhanjun Li,Kai Huang,Xin Fang,Zishuo Li,Minghong Wang,Wenhui Liu,Jia-Nan Li,Longfei Li,Hang Zhao,Min Wei,Yiming Shi,Rong Liu,Mei Zhang,Jutao Chen,Jiawei Shen,Jianjun Meng,Yupeng Yang,Fan Zhang,Xinglong Gong,Gang Han,Tian Xue

Humans cannot perceive infrared light due to the physical thermodynamic properties of photon-detecting opsins. However, the capability to detect invisible multispectral infrared light with the naked eye is highly desirable. Here, we report wearable near-infrared (NIR) upconversion contact lenses (UCLs) with suitable optical properties, hydrophilicity, flexibility, and biocompatibility. Mice with UCLs could recognize NIR temporal and spatial information and make behavioral decisions. Furthermore, human participants wearing UCLs could discriminate NIR information, including temporal coding and spatial images. Notably, we have developed trichromatic UCLs (tUCLs), allowing humans to distinguish multiple spectra of NIR light, which can function as three primary colors, thereby achieving human NIR spatiotemporal color vision. Our research opens up the potential of wearable polymeric materials for non-invasive NIR vision, assisting humans in perceiving and transmitting temporal, spatial, and color dimensions of NIR light.

研究领域: 生物医学工程 · 神经科学 · 材料科学
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OPTICAL MATERIALS · 2021 · IF 3.08

Alkali-assisted synthesis of gourd flesh derived tricolor F/N co-doped carbon dots for efficient degradation of organic dyes

Congling Wang,Jun Xu,Huizhi Li,Weilin Zhao

A novel tricolor F/N co-doped CDs was synthesized by alkali-assisted control with gourd flesh as a precursor, targeting at the catalytic degradation of organic dyes with extremely high catalysis rate. The synthesized nanomaterials were characterized by X-ray diffraction, Transmission electron microscopy , Fourier transform infrared spectra and X-ray photoelectron spectroscopy techniques, indicating that the tricolor F/N-CDs have good dispersion and abundant surface defects which were gradually increasing from F/N-G-CDs, F/N-Y-CDs to F/N- O -CDs. Through the UV–visible and fluorescence spectra , the tricolor F/N-CDs all exhibited good fluorescence performance and the fluorescence lifetime was nano-scale level. The tricolor F/N-CDs displayed excellent photocatalytic activity which was evaluated by the organic dyes methylene blue (MB) and congo red (CR) as models. The important thing is that under sunlight irradiation, the degradation efficiency of using tricolor F/N-CDs for MB reaches ~100% and the degradation efficiency for CR dye reaches ~98% in a pole short time. With the red shift of the fluorescent tricolor F/N-CDs, the degradation time gradually decreased and the degradation rate gradually increased. The results explained that the prepared tricolor F/N-CDs had excellent application prospects in the natural degradation.

CAS / MDL: 1310-73-2
研究领域: 材料科学 · 环境科学
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PEST MANAGEMENT SCIENCE · 2023 · IF 4.1

Activity of the botanical compound thymol against kiwifruit rot caused by Fusarium tricinctum and the underlying mechanisms

Weizhen Wang,Linan He,Zhuzhu Zhang,Wenzhi Li,Jia Chen,Tingting Chen,Youhua Long

BACKGROUND Kiwifruit rot is an important disease caused by different fungal pathogens, which can lead to huge economic loss in the kiwifruit industry. The aims of this study were to discover an effective botanical compound that significantly inhibits the pathogens causing kiwifruit rot, evaluate its control efficacy against this disease, and reveal the underlying mechanisms. RESULTS A strain of Fusarium tricinctum (GF-1), isolated from diseased kiwifruit, could cause fruit rot in both Actinidia chinensis var. chinensis and Actinidia chinensis var. deliciosa . Different botanical chemicals were used for antifungal activity test against GF-1 and thymol was the most effective one with a 50% effective concentration (EC 50 ) of 30.98 mg L −1 . The minimal inhibitory concentration (MIC) of thymol against GF-1 was 90 mg L −1 . Control efficacy of thymol against kiwifruit rot was evaluated and the results indicated that thymol could effectively decrease the occurrence and spread of kiwifruit rot. The mechanisms underlying the antifungal activity of thymol against F. tricinctum were investigated, and it showed that thymol could significantly damage the ultrastructure, destroy the plasma membrane integrity, and instantaneously increase energy metabolisms of F. tricinctum . Further investigations indicated that thymol could extend shelf life of kiwifruit by increasing their storability. CONCLUSION Thymol can effectively inhibit F. tricinctum that is one of the causal agents of kiwifruit rot. Multiple modes of action are involved in the antifungal activity. The results of this study indicate that thymol can be a promising botanical fungicide to control kiwifruit rot and provide useful references for thymol application in agriculture system. © 2023 Society of Chemical Industry.

研究领域: 植物病理学 · 农业化学 · 食品科学
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International Journal of Analytical Chemistry · 2022 · IF 1.698

Novel Organic-Inorganic Hybrid Polystyrene Nanoparticles with Trichromatic Luminescence for the Detection of Latent Fingerprints

Xiao Wang,Tao Liao,Haiyan Wang,Hongxia Hao,Qinglai Yang,Hong Zhou,Yu Ma,Minjie Zhi,Jiahao Wang,Ruihang Fan

This article explored the application of novel organic-inorganic hybrid polystyrene nanoparticles (PSNPs) with trichromatic luminescence for the detection of latent fingerprints. The PSNPs were synthesized by encapsulated Eu(DBM)3phen, coumarin 6, and FDBT into the polystyrene nanoparticles through the swelling method and applied them to visualize latent fingerprints. The PSNPs had a spherical morphology with an average diameter of 310.7 nm, and they emitted trichromatic fluorescence (525 nm/570 nm/610 nm) under 365 nm excitation wavelength with green/yellow/red color under filters. They were less likely to aggregate, float or stain the background when treating fingerprints. The developed fingerprints with excellent clarity of ridges and contrast could be viewed, and the digital magnification of fluorescence-developed fingerprints provided more minutiae details about some regional patterns. The colorimetric and fluorescent trichromatic light could provide complementary signals without the background interference from fluorescent substrates and/or complex multicolor surfaces, which improved the applicability of fluorescent nanoparticles for fingerprints development. PSNPs are promising for the detection of latent fingerprints and practical criminal investigations with their ease of operation, eco-friendly properties, and excellent trichromatic optical performance.

研究领域: 材料科学 · 法医学 · 光学
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Advanced Optical Materials · 2024 · IF 8

Mn2+-Doped Hybrid Halides with Excitation-Dependent Tricolor Luminescence for All-Optical Logic Gate Operations

Yuzhen Wang,Qian Zhu,Jiance Jin,Wei Liao,Zhiguo Xia

All-optical logic gates (AOLGs) have attracted considerable attention for their high computing speed, low power consumption, and parallel processing; however, chemical design of new luminescent materials is a challenge to explore a facile platform for undertaking AOLGs. Here, an AOLG system is developed based on the organic–inorganic hybrid halides [NH 3 (CH 2 ) 2 NH 3 ] 2 ZnCl 6 :Mn 2+ with tricolor luminescence under dual-wavelength excitation, and the intrinsic emission mechanisms are further addressed. When employing 275 and 365 nm UV excitations as input signals, the AOLGs conduct Boolean operations “OR, YES, AND” via identifying the green (G) and red (R) emissions and their intensity ratio (R/G) as output signals. This work further demonstrates the AOLG operation imaging and image processing via hybrid halide emitters, indicating promise in optical computing applications.

CAS / MDL: 7773-01-5 7646-85-7
研究领域: 材料科学 · 光电 · 光子学 · 计算光学
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ADVANCED FUNCTIONAL MATERIALS · 2020 ·Vol. 30 ·期 42 ·2004532 · IF 16.836

An Intrinsically Nontrimerizing Peptide Probe for Specifically Targeting Pathological Collagen in Connective Tissues

Xiangdong Cai,Wenyu Wei,Yihui Bi,Zhao Liu,Zhongtian Bai,Junqiang Lei,Jianxi Xiao

The efficient detection of pathological collagen plays an essential role in the diagnosis, prognosis, and treatment of various critical diseases such as arthritis and tumors. Peptide probes with the (Gly-Pro-Hyp)n sequences have been recently discovered to recognize pathological collagen; however, their staining efficacy severely suffers from their strong trimerizing tendency. An intrinsically nontrimerizing peptide probe F-GOP-10 has been constructed for the first time to specifically target pathological collagen. F-GOP-10 consists of the repetitive (Gly-Hyp-Pro)n sequences, and displays the single stranded conformation at 0 °C. F-GOP-10 has been demonstrated to selectively recognize pathological, but not intact collagen in various mouse connective tissues, and it has been successfully applied to detect pathological collagen in osteoarthritis, liver fibrosis, and various cancer tissues. Compared with the common Masson's trichrome staining method, F-GOP-10 displays unique selectivity to only bind to pathological collagen without the interference of intact collagen. Notably, peptide probes with different lengths of the Gly-Hyp-Pro triplets all maintain the single stranded conformation, demonstrating their intrinsically non-trimerizing nature. This pure-peptide, pure monomer probe allows the accurate concentration determination and the elimination of harmful pretreatment, which has great potential in histopathology staining and other clinical applications.

CAS / MDL: 72088-94-9
研究领域: 医学诊断 · 病理学 · 分子生物学 · 生物医学工程
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ANALYTICAL CHEMISTRY · 2025 · IF 6.7

Aptamer-Engineered Trichromatic Colloidal Crystal Biosensor for High-Precision Visual Sensing of Oxytetracycline

Hanwen Li,Yonghao Wang,Lingquan Zeng,Chuyun Jin,Peng Zhang,Fenglian Qi,Caifeng Ding

Precision chromatic sensing remains a critical challenge for environmental diagnostics due to limited color resolution in field-deployable platforms. Herein, we present an aptamer-engineered trichromatic colloidal crystal hydrogel (ATCCH) biosensor that integrates triple colloidal crystal arrays with oxytetracycline (OTC)-specific molecular recognition. This system combines programmable stepwise vertical deposition of SiO2 colloids with the formation of OTC-specific aptamers anchored through gold nanoparticle (AuNP) bridges, creating nanoconfined sensing cavities for target-triggered photonic band gap modulation. OTC binding triggers aptamer structural transitions via π–π stacking and hydrogen bonding, disrupting AuNP-mediated cross-linking and inducing synergistic lattice expansion across three photonic domains. This generates independent wavelength shifts (R: 867 → 921 nm, G: 723 → 771 nm, B: 548 → 601 nm) with cooperative naked-eye-discernible color transitions (R: pale red → red, G: indigo → brick yellow, B: purple → blue) as the concentrations of OTC increased from 0.1 to 100 μg/mL. The three-dimensional nanoconfinement architecture enables ultrastable operation in high-ionic-strength environments (0.5 M NaCl), achieving a detection limit low to 33 ng/mL via reflection spectroscopy (0.1–80 μg/mL log–linear range, R2 = 0.966:0.956:0.992 for R/G/B domains) and field-applicable chromatic thresholds (0.5 μg/mL) matching aquaculture safety standards. The triple-signal synergy enhances color resolution by at least 2-fold compared with monochromatic systems. This multichromatic photonic-aptamer nanoengineering strategy establishes a new paradigm for field-deployable environmental sensors that bridge laboratory-grade quantification with instant visual readouts.

CAS / MDL: 6175-45-7
研究领域: 环境监测 · 生物传感技术 · 纳米技术 · 光学传感 · 分析化学
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SENSORS AND ACTUATORS B-CHEMICAL · 2019 · IF 6.393

Tricolor emissive carbon dots for ultra-wide range pH test papers and bioimaging

Tianyi Zhang,Si Dong,Feifei Zhao,Mingxiao Deng,Yuqin Fu,Changli Lü

Recently, fluorescent pH test paper has been extensively explored for visual assays due to its easy preparation, low-cost, and portable feature. In addition, intracellular pH also plays important roles in different pathological and physiological processes for understanding cellular functions and providing critical assistance for early disease diagnosis. Herein, the tricolor emission [email protected] carbon dots (CDs) were synthesized via one-pot hydrothermal method using 5-amino-1,10-phenanthroline (Aphen) and citric acid (CA) as the carbon sources. The fluorescence emission of CDs showed an interesting pH dependence due to the special structure and properties, which can make the CDs to be used as the pH test paper to qualitatively and quantitatively detect pH value in a wide pH range. At the same time, because of good cell compatibility and low toxicity, CDs can be used as a new type of cell imaging marker to detect intracellular pH. The unique tricolor emission property of CDs can well avoid the fluorescent dyes and protein fluorescence interference.

研究领域: 材料科学 · 分析化学 · 生物医学工程 · 细胞生物学
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JOURNAL OF FOOD COMPOSITION AND ANALYSIS · 2025 · IF 4.6

First microstructure insights into the dynamic degradation of structural proteins components of shrimp Litopenaeus vannamei during refrigeration and its association with texture deterioration: Based on histochemical staining and biochemical analysis

Shaoping Zhu,Li Hu,Jiaxin He,Jun Feng,Caihong Li,Defeng Xu

This study aims to establish a histological protocol to visualize the process of structural protein degradation in shrimp Litopenaeus vannamei during refrigeration. After fixed in Carnoy’s fixative for 15 h at room temperature and combined with Masson’s trichrome staining, the structural components of myofibrils and collagen were effectively visualized and the pathological analysis revealed the widened gaps between muscle bundles and the disrupted myofibrils were observed. Moreover, the lighter staining in collagen component was observed during the cold storage, indicating its progressive reduction in content. Quantitatively, the myofibril cross-sectional and longitudinal volume fractions dropped from (91.03 ± 1.37) % and (93.39 ± 0.91 %) to (41.14 ± 3.78) % and (24.36 ± 3.67) % (Day 5, P  < 0.01), respectively. Meanwhile, the collagen and myofibril areas were negatively correlated with the parameters of hardness and elasticity ( P  < 0.05), confirming their role in inducing texture quality deterioration. Collectively, by visualizing the degradation process of structural components collagen and myofibril in shrimp muscle during refrigeration, the association between structural proteins degradation and texture deterioration was identified. This study identifies a potential biomarker of early muscle softening in refrigerated shrimp L. vannamei and provides a solid foundation for its industrial application in quality control of shrimp during preservation.

研究领域: 食品科学 · 海洋生物学 · 组织学 · 生物化学 · 采后生理学
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ACS Sustainable Chemistry & Engineering · 2023 · IF 8.4

Tricolor Pattern Design: Ultrahigh Thermal Conductivity Phosphor-in-Glass Film for Laser Illumination

Cong Zhao,Qianxiong Wen,Shuyang Bao,Shuang Pan,Weidong Xiang,Xiaojuan Liang

Solid-state laser lighting has gradually become dominant in the display and illumination market, benefiting from its high efficiency and ultrahigh luminescence properties. Herein, by intelligently designing glass components and minor BN addition, a high-transparency and heat-resistant phosphor-in-glass film (PiGF) (a zero-thermal-quenching phenomenon) is realized. Further, in an attempt to take into account both the excellent luminous performance and the high quality of the light colors, a uniquely designed tricolor pattern of PiGF (THP-PiGF) was fabricated as an alternative to high-power white laser illumination. Under the excitation of a 450 nm blue laser diode (LD), a luminous efficiency (LE) of 159.87 lm/W with high color rendering index (CRI = 87.2) is achieved at 9.32 W/mm2. THP-PiGF with ultrahigh thermal conductivity (16.984 W/(m K)) can withstand a long operation time of 300 min under constant incident blue laser illumination. With respect to practical applications, a high-power laser module (maximum power 74 W) is assembled with the unique PiGF which can emit an interesting THP. These contributions can substantially drive the development of state-of-the-art laser light illumination.

研究领域: 材料科学 · 光电技术 · 光子学 · 照明工程
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ACS Applied Materials & Interfaces · 2018 · IF 8.097

Tricolor White-Light-Emitting Carbon Dots with Multiple-Cores@Shell Structure for WLED Application

Tianyi Zhang,Feifei Zhao,Li Li,Bin Qi,Dongxia Zhu,Jianhua Lü,Changli Lü

The past few years have witnessed the rapid development of carbon dots (CDs) due to their outstanding optical properties and a wide range of applications. However, the design and control of CDs with long-wavelength multicolor emission are still huge challenges to be addressed for their practical use in different fields. Here, novel nitrogen-doped multiple-core@shell-structured AC-CDs with tricolor emissions of red, green, and blue were constructed via one-pot hydrothermal method from 5-amino-1,10-phenanthroline and citric acid as reactants and the growth process of AC-CDs was monitored with the reaction time in the synthetic system. The origin of different fluorescence emissions was explored using the unique coordination ability of the surface groups of AC-CDs. An obvious concentration dependence of fluorescent properties was observed for the as-prepared AC-CDs, and a highly fluorescent quantum yield (QY) of 67% for red emission at 630 nm can be obtained by adjusting concentration of AC-CDs. The pure white-light emission (0.33, 0.33; Commission Internationale de l’Elcairage coordinate) was carried out from single carbon dot with QY of 29% through regulation of the excitation and concentration of multiple-core@shell-structured AC-CDs. In addition, because of their excellent photoluminescent properties, the white-emitting AC-CDs as emitting phosphor can be easily used in the fabrication of white-light-emitting diode with good anti-photobleaching and temperature stability.

CAS / MDL: 77-92-9 5949-29-1
研究领域: 材料科学 · 光电技术 · 纳米技术 · 光子学
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