SENSORS AND ACTUATORS B-CHEMICAL
·
2022
·
IF 9.221
Yuhuan Zhang,Hongjuan Li,Shiguo Sun,Yongqian Xu
Triphenylphosphine (PPh 3 ) and tetrakis(triphenylphosphine)palladium (Pd(PPh 3 ) 4 ) are harmful at extremely low concentration, thus it is essential to explore selective and sensitive method to detect them. Based on Staudinger reaction mechanism, here we present a simple excited-state intramolecular proton transfer (ESIPT) fluorescent probe (HBTN) for detection of PPh 3 and Pd(PPh 3 ) 4 over other phosphine derivatives with differential channel fluorescence (enol and keto emission). The reaction-typed fluorescence probe with novel Staudinger reaction mechanism offers very low autofluorescence and a large signal-to-noise response signal, which is beneficial for the sensitive detection of PPh 3 and Pd(PPh 3 ) 4 . Moreover, HBTN can be used for efficiently detecting Pd(PPh 3 ) 4 residues in highly purified products and imaging PPh 3 in living cells.
研究领域:
分析化学
·
生物医学
✓ 已验证
DOI
高影响因子
Journal of Energy Chemistry
·
2025
·
IF 14.9
Kangming Ou,Jiale Liu,Junwei Xiang,Chaoyang Wang,Jiayu Xie,Xiaoyu Li,Yanjie Cheng,Qiaojiao Gao,Lingya Gao,Anyi Mei,Yang Zhou,Hongwei Han
The stacking of multiple defect-rich grain boundaries (GBs) along the long transportation path (∼3 μm) of charge carriers in printable mesoscopic perovskite solar cells (p-MPSCs) impedes their power conversion efficiency (PCE). Organic Lewis bases are widely utilized for defect passivation at GBs, but how their passivation efficiency affects energy loss remains unclear. Here we employed triphenylphosphine (TPP) and triphenylphosphine oxide (TPPO) as the model passivators in p-MPSCs. TPPO has a more negatively charged center than TPP, which enables its stronger coordination with one of the most common and detrimental defects at the GBs—undercoordinated lead. When added into the perovskite with the same ratio, TPPO passivates defects more significantly and thus less TPPO remaining inactive compared with TPP. Inactive organic passivators accumulated at the GBs could impose barriers to charge carrier transportation. Indeed, TPPO improves the device performance more significantly with a champion PCE of 20.54% achieved. Besides, the TPPO devices demonstrate excellent stability with 95% of initial PCE remaining after 600 h of maximum power point tracking at (55 ± 5)°C.
研究领域:
材料科学
·
能源科学
✓ 已验证
产品关联
DOI
高影响因子
ADVANCED FUNCTIONAL MATERIALS
·
2019
·Vol. 29
·期 50
·1906587
·
IF 15.621
Guangjun Zhang,Jirui Feng,Xiaopeng Xu,Wei Ma,Ying Li,Qiang Peng
A series of perylene diimide (PDI) derivatives, TPP-PDI , TPO-PDI , and TPS-PDI , are developed for nonfullerene polymer solar cells (NF-PSCs) by flaking three PDI skeletons around 3D central cores with different configurations and electronic states, such as triphenylphosphine (TPP), triphenylphosphine monoxide (TPO), and triphenylphosphine sulfide (TPS). These small-molecule acceptors have a “three-wing propeller” structure due to their similar backbones. By changing the electron density of phosphorus atoms through oxidation and sulfuration, the “folding-back” strength is decreased, resulting in a less twisted molecular conformation. The stronger electron-withdrawing ability of the oxygen atom affords TPO-PDI the least twisted conformation, which enhances the crystallinity of this complex. NF-PSCs based on PTTEA : TPO-PDI exhibit a high power conversion efficiency (PCE) of 8.65%. Ultimately, the joint “molecular lock” effect arising from O H⋅⋅⋅F and O H⋅⋅⋅OP supramolecular interactions is achieved by introducing 4,4′-biphenol as an additive, which successfully promotes fibril-like phase separation and blend morphology optimization to generate the highest PCE of 11.01%, which is currently the highest value recorded for NF-PSCs based on PDI acceptors.
研究领域:
材料科学
·
有机电子学
·
高分子化学
·
纳米技术
·
光化学
✓ 已验证
DOI
高影响因子
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
·
2019
·Vol. 26
·期 25
·25445-25451
·
IF 2.914
Yi Xianliang,Wang Jianfeng,Li Zhaochuan,Zhang Zherui,Chi Tongtong,Guo Miao,Li Wentao,Zhou Hao
The effect of polystyrene (PS) particles on the toxicity of triphenyltin (TPT) to the marine diatom Skeletonema costatum was investigated. The 0.1-μm PS particles attached to the cell walls of S. costatum but did not cause adverse effects on the growth of the diatom. The adsorption of TPT to PS particles was negligible in seawater systems, but the presence of 0.1-μm PS significantly reduced the bioavailable concentrations of TPT in f/2-Si medium, indicating a potential three-way interaction between TPT, PS particles, and components of f/2-Si medium. The adsorption of TPT to PS of smaller size (i.e., 0.1 μm) was stronger than that of PS of larger size (i.e., 5 μm), which was probably attributed to larger surface areas of smaller PS particles. The presence of PS could reduce the toxicity of TPT. IC 50 values of TPT increased from 0.56 to 0.85 and 0.71 μg/L at the presence of 20 mg/L 0.1-μm PS and 5-μm PS, respectively. The overall results of this study profiled the combined toxic effects of PS and TPT on marine phytoplankton species and highlighted the difference in adsorption of organic pollutants by microplastics in different ambient mediums.
研究领域:
海洋生物学
·
环境科学
✓ 已验证
DOI
PubMed
高影响因子
JOURNAL OF HAZARDOUS MATERIALS
·
2024
·
IF 12.2
Dandan Li,Chen Xie,Ziwu Fan,Rui Ding,Xiaoyu Wang,Yipeng Liao
The ubiquitous co-existence of triphenyl phosphate (TPhP) and heavy metals in sediments raises significant biotoxicity concerns. However, uncertainty still exists regarding their combined toxicity to benthic organisms. Therefore, this research was conducted to elucidate the influences of cadmium (Cd) on TPhP toxicity to Corbicula fluminea ( C. fluminea ) in sediments. As a result, Cd promoted the accumulation of TPhP in C. fluminea and enhanced TPhP toxicity, manifested by damaged cell membranes and pronounced histological alterations. Molecular docking revealed that TPhP-Cd complexes exhibit greater binding affinity to cytochrome P4501A1 (CYP1A1) compared to TPhP alone. With the activity of CYP1A1 increasing, the biotransformation of TPhP was promoted in low-TPhP+Cd treatments (T5C0/T5C5/T5C35). Additionally, metabolites related to antioxidant defence and repair processes were reinforced to alleviate the toxicity of TPhP and Cd. However, excessive oxidative stress impaired the CYP1A1 activity in high-TPhP+Cd treatments (T35C0/T35C5/T35C35). Furthermore, metabolic pathway analysis revealed significant perturbations in the citrate cycle , alanine, aspartate and glutamate metabolism , purine metabolism, and pyrimidine metabolism . These disruptions weakened the repair capacity and aggravated apoptosis in digestive glands, potentially contributing to the synergistic toxicity of TPhP and Cd. The results highlight the ecological risks posed by TPhP in combination with heavy metals to benthic organisms.
研究领域:
环境科学
·
毒理学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF HAZARDOUS MATERIALS
·
2025
·
IF 11.3
Dandan Li,Xiaoyu Wang,Chen Xie,Ziwu Fan,Rui Ding,Songqi Liu,Yu Chen,Kai Yu
The widespread co−existence of triphenyl phosphate (TPhP) and heavy metals in sediments raises significant concerns. However, uncertainty still exists regarding the degradation characteristics of TPhP in the presence of cadmium (Cd). Therefore, this research was conducted to elucidate the impacts of Cd on TPhP degradation in sediments. Results showed that the biodegradation efficiency of TPhP in sediments exceeded 90 %. The identified degradation products of TPhP indicated that the degradation pathway primarily involved oxidative cleavage, hydroxylation, and methylation, which was further supported by condensed dual descriptors (CDD). However, the presence of Cd significantly inhibited TPhP degradation, with greater inhibition at higher concentrations of both TPhP and Cd. Transcriptomic analysis revealed that xenobiotic metabolism was significantly suppressed. Furthermore, pathways associated with cell motility, membrane transport, and energy metabolism were impaired. These disruptions likely contributed to the decreased degradation efficiency and prolonged half−life of TPhP. Interestingly, biomarkers in Firmicutes were enriched in the high−concentration TPhP + Cd treatment and strongly correlated with degradation−related gene expression, suggesting their significance in TPhP degradation under heavy metal stress. Overall, this research provides insights into the inhibitory effects of Cd on TPhP degradation and offers theoretical support for the bioremediation of TPhP−contaminated sediments with heavy metals.
研究领域:
环境科学
·
分子生物学
·
计算化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
SCIENCE OF THE TOTAL ENVIRONMENT
·
2019
·
IF 5.589
Qingyun Song,Yiping Feng,Zhu Wang,Guoguang Liu,Wenying Lv
The aryl organophosphate flame retardant triphenyl phosphate (TPhP) has been frequently detected in environment and biota, and the potential risks of TPhP to aquatic organisms have also been demonstrated. The degradation of TPhP by CoFe 2 O 4 activated peroxymonosulfate (PMS) was studied in this work. At initial pH of 7.0, 10 μM TPhP could be removed by 99.5% with 0.25 g/L CoFe 2 O 4 and 0.5 mM PMS after 6 min oxidation, indicating the excellent performance of CoFe 2 O 4 activated PMS process on the treatment of TPhP. The influence of PMS and CoFe 2 O 4 dosage, initial pH, humic acid (HA), and anions (Cl − , NO 3 − , and HCO 3 − ) on TPhP degradation were investigated systematically. Results showed that the degradation of TPhP was enhanced with increasing PMS concentrations from 0.1 to 1 mM, while it reduced as CoFe 2 O 4 dosage increased. TPhP degradation efficiencies depended on solution pH with neutral pH showing the optimum degradation conditions. Recycling experiment indicated that the CoFe 2 O 4 nanoparticles (NPs) possessed high potential for reusability. The radical identification experiments were performed and SO 4 • − was confirmed as the dominant radicals in TPhP degradation, and activation mechanism of PMS by CoFe 2 O 4 NPs was hence explained. Humic acids (HA) (2–20 mg/L) as the representative organic natural matter existing in environment inhibited TPhP removal. Anions including Cl − , NO 3 − , and HCO 3 – all reduced TPhP degradation. In addition, TPhP degradation products were identified by liquid chromatography-mass spectrometry, and the degradation pathways of TPhP were proposed accordingly.
研究领域:
环境科学
·
化学工程
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF SOILS AND SEDIMENTS
·
2022
·Vol. 22
·期 7
·2062-2075
·
IF 3.536
Li Dandan,Wang Peifang,Wang Xun,Hu Bin
Purpose Owing to urbanization and industrial pollution, co-contamination of triphenyl phosphate (TPhP) and heavy metals is ubiquitous in aquatic sediments. However, the influence of coexisting heavy metals on TPhP transport remains unclear. Therefore, it is necessary to investigate the influence of coexisting heavy metals (Cd 2+ ) on the behaviors of TPhP on sediments. Methods Mathematical equations were used to describe the adsorption/desorption process of TPhP on different sediments in the presence of Cd 2+ , and the underlying mechanism was proposed at the molecular level. Results The Fourier-transform infrared (FTIR) spectra showed that Cd 2+ could complex with P = O of TPhP, interact with oxygen-containing functional groups of sediments, which generated additional sorption sites for TPhP, and modified sediments properties. Therefore, the sorption amount of TPhP on sediments was promoted at 10 μmol L −1 Cd 2+ . Furthermore, Cd 2+ could also compete for sorption sites against TPhP. At 100 μmol L −1 Cd 2+ , the adverse effect overpassed the facilitatory effect caused by Cd 2+ , leading to the decrease of sorption amounts of TPhP. Additionally, the redundancy analysis indicated that the sorption amount of TPhP with Cd 2+ coexisting had a positive correlation with sediment organic matter (SOM), C/H, and zeta potential of sediments. With regard to desorption, organic matter condensed by Cd 2+ , and the complexes formed by TPhP with Cd 2+ , slowed down the diffusion rate, and increased the possibility of the entrapment of TPhP in holes. Conclusion The sorption amounts of TPhP on sediments were increased at low Cd 2+ concentration, and decreased at high Cd 2+ concentration. Furthermore, the presence of Cd 2+ could exacerbate the TPhP hysteresis on sediments. This research provides more comprehensive information on TPhP behaviors and facilitates more accurate assessment of the ecological risks posed by TPhP in sediments contaminated with heavy metals. Graphical abstract
研究领域:
环境科学
·
污染生态学
✓ 已验证
产品关联
DOI
高影响因子
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
·
2025
·Vol. 26
·期 11
·5280
·
IF 4.9
Hongjuan Cui,Yan Zhao,Wei Li,Huanjie Cui,Jiahong Han,Enbo Cai
Formononetin is widely used in anti-tumor research, but its poor water solubility leads to low absorption and poor utilization efficiency in vivo, limiting further development. The triphenylphosphine cation was partially attached to the 7-position hydroxyl group of formononetin to specifically target it into the mitochondria of tumor cells to enhance the anti-tumor effect. Detailed structural characterization via 1 H-NMR and 13 C-NMR analysis confirmed the physical properties and chemical structures of 21 newly synthesized derivatives. The effects of these derivatives on tumor cells were assessed by in vitro and computational methods. MTT results from four tumor cell lines showed that formononetin derivatives containing triphenylphosphine had stronger anti-tumor activity than formononetin and exhibited more cytotoxic effects in cancer cells than in normal cells. In particular, the final product 2c (IC 50 = 12.19 ± 1.52 μM) showed more potent anti-tumor activity against A549 cells. It was also superior to formononetin and 5-FU. To identify the potential biological targets, the core-expressed gene SHMT2 in lung cancer mitochondria was screened using network pharmacology technology, and molecular docking analysis confirmed the stable binding of the end products to the amino acid residues of the core genes through the formation of hydrogen bonds and via other interactions. In addition, molecular docking simulations further confirmed that the end product exhibited excellent stability when bound to SHMT2 . These results suggest that triphenylphosphine-containing formononetin derivatives are worthy of further exploration in the search for novel drug candidates for the treatment of cancer.
研究领域:
药理学
·
肿瘤学
·
计算生物学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
LIQUID CRYSTALS
·
2012
·
IF 1.858
Fafu Yang,Jianwei Xie,Hongyu Guo,Bingting Xu,Congcong Li
Series of novel 1,3,5-triazine-based triphenylene oligomers 7, 10 and 12 with large bridging polyaromatic core were designed and synthesised by simple procedures in high yields. Their structures were confirmed by FTIR, 1H NMR, ESI-MS and elemental analyses. Their mesomorphic behaviours were studied by differential scanning calorimetry, polarising optical microscopy and X-ray diffraction. 1,3,5-triazine-based triphenylene monomer 7 has no mesomorphic property, but 1,3,5-triazine-based triphenylene dimer 10 and 1,3,5-triazine-based triphenylene trimer 12 possess excellent mesomorphic properties. The mesomorphic temperature range of compound 12 was as wide as 180°C. These studies indicated that the mesomorphic properties were determined by the numbers of triphenylene units. More units of triphenylene in the oligomers resulted in better mesomorphic properties.
研究领域:
材料科学
·
化学
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF CHEMICAL THERMODYNAMICS
·
2022
·
IF 3.269
Shumin Xue,Jun Chu,Huanxin Yin,Xunqiu Wang
The gravimetric method was used to determine the solubility of triphenylphosphine in four mono-solvents (acetonitrile, tetrahydrofuran, cyclohexane, ethyl acetate) and two binary mixed solvents (acetonitrile + tetrahydrofuran, ethyl acetate + tetrahydrofuran) at normal pressure and temperature range (288.15 K-328.15 K). The results show that the solubility of triphenylphosphine in the selected solvent increased with the increase of temperature within the temperature range studied. In the binary mixed solvent (ethyl acetate + tetrahydrofuran, acetonitrile + tetrahydrofuran), the solubility of triphenylphosphine increased with the increase of the mass fraction of tetrahydrofuran. In addition, the Hansen solubility parameter (HSP) was used to explain the dissolution behavior of triphenylphosphine. The solubility data were fitted by the modified Apelblat equation, van't Hoff equation, λh equation, Apelblat-Sun equation and NRTL model. The results show that the modified Apelblat equation and van't Hoff equation have a better fitting effect on the solubility data of triphenylphosphine in the mono-solvents used in the experiment, and the modified Apelblat equation has a better fitting effect on the solubility data of triphenylphosphine in the binary mixed solvent used in the experiment. The fitting results can provide some basic data for the optimization of the crystallization process of triphenylphosphine. The thermodynamic properties of the dissolution process of triphenylphosphine in the selected solvent were calculated and discussed by van't Hoff equation, and the thermodynamic properties of the solution (Δ dis H , Δ dis S and Δ dis G ) were all positive values, which increased that the mixing and dissolution of triphenylphosphine in the selected solvent are endothermic and entropy-driven. This study can provide basic thermodynamic data for the crystallization and industrial separation of triphenylphosphine.
研究领域:
化学工程
·
物理化学
✓ 已验证
产品关联
DOI
高影响因子
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
·
2019
·Vol. 26
·期 15
·15011-15018
·
IF 2.914
Yi Xianliang,Chi Tongtong,Li Zhaochuan,Wang Jianfeng,Yu Mingyue,Wu Minghuo,Zhou Hao
The combined effect of polystyrene (PS) particles and triphenyltin chloride (TPTCl) to the green algae Chlorella pyrenoido s a was studied. The 96 h IC 50 of TPTCl to the green algae C. pyrenoidosa was 30.64 μg/L. The toxicity of PS particles to C. pyrenoidosa was size-dependent, with the 96 h IC 50 at 9.10 mg/L for 0.55 μm PS but no toxicity observed for 5.0 μm PS. The exposure to 0.55 μm PS led to damage on structure of algal cells, which could in turn cause inhibition on photosynthesis and population growth of the green algae. TPTCl concentrations in test medium were lowered by 15–19% at presence of 0.55 μm PS particles, indicating a reduced bioavailability of TPTCl. In spite of this reduced bioavailability, the presence of PS increased the toxicity of TPTCl, which might be attributed to facilitated uptake of TPTCl by the green algae after the damage of cell structure. The overall results of the present study provided important information on the effect of PS on the bioavailability and toxicity of TPTCl to phytoplankton species.
研究领域:
环境科学
·
毒理学
✓ 已验证
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）