OPTICAL MATERIALS
·
2020
·
IF 2.779
Yue Liang,Linghui Shen,Tong Wei,Chuanzhen Zhao,Bing Jia,Yong Shi,Shengcheng Wu
Up-conversion nanoparticles (UCNPs) stimulated by near-infrared (NIR) light have received immense interest for their potential applications in many fields. In this work, Nd 3+ - and Yb 3+ -sensitized Bi 4 Ti 3 O 12 (BiT x :Nd 3+ /Yb 3+ , 0.005 ≤ x ≤ 0.3) UCNPs with thermometric and photo-thermal (PT) functions were successfully synthesized by a convenient co-precipitation approach, and the phase and morphologies were characterized. Under 980 nm excitation, BiT x :Nd 3+ /Yb 3+ UCNPs exhibited remarkable multiple emissions in the region from 450 to 900 nm. The visible and NIR emissions were tightly dependent on the Nd 3+ concentration and the strongest NIR emissions were obtained in sample BiT0.3:Nd 3+ /Yb 3+ . The possible UC mechanisms and processes were proposed. Furthermore, the capability of the UCNPs as thermometers was probed based on the thermo-responsive fluorescence intensity ratio technique in the temperature range 303–573 K. The maximum sensitivity (S max ) of BiT0.3:Nd 3+ /Yb 3+ was determined to be as high as 0.032 K -1 . Meanwhile, PT effect was evaluated by monitoring the variation of surface temperature of the sample as functions of irradiation time and power density. Conspicuous PT effect was confirmed and the maximum temperature induced by laser was about 91 °C. These results reveal that BiT0.3:Nd 3+ /Yb 3+ UCNPs has promising potential applications as optical thermometer and heater.
研究领域:
材料科学
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光学
·
生物医学工程
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产品关联
DOI
高影响因子
Polymers
·
2020
·Vol. 12
·期 11
·2592
·
IF 3.426
Mingcong Hao,Tongtong Wu,Qunzhi Chen,Xueyan Lian,Haigang Wu,Bingyang Shi
Owing to the wide spectrum of excitation wavelengths of up-conversion nanoparticles (UCNPs) by precisely regulating the percentage of doping elements, UCNPs have been emerging as bioimaging agents. The key drawback of UCNPs is their poor dispersibility in aqueous solution and it is hard to introduce the chemical versatility of function groups. In our study, we present a robust and feasible UCNP modification approach by introducing hyperbranched polyglycerols (hbPGs) as a coating layer. When grafted by hbPGs, the solubility and biocompatibility of UCNPs are significantly improved. Moreover, we also systematically investigated and optimized the chemical modification approach of amino acids or green fluorescence protein (GFP), respectively, grafting onto hbPGs and hbPGs-g-UCNP by oxidizing the vicinal diol to be an aldehyde group, which reacts more feasibly with amino-containing functional molecules. Then, we investigated the drug-encapsulating properties of hbPGs-Arg with DOX and cell imaging of GFP-grafted hbPGs-g-UCNP, respectively. The excellent cell imaging in tumor cells indicated that hbPG-modification of UCNPs displayed potential for applications in drug delivery and disease diagnosis.Keywords:hyperbranched polyglycerols;up-conversion nanoparticle;bioimaging
研究领域:
材料科学
·
生物医学工程
·
纳米医学
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产品关联
DOI
PubMed
高影响因子
CRYSTENGCOMM
·
2024
·Vol. 26
·期 10
·1371-1379
·
IF 2.6
Meijuan Liu,Ying Chen,Xuegang Zheng,Haonan Zhao,Shusheng Pan,Zhiyu Liu,Dekang Xu,Hao Lin
In this study, a series of LiErF4:Tm@LiYF4:Yb,Er,Ce@LiYF4 core/shell/shell (C/S/S) UC nanoparticles (UCNPs) were prepared by a co-precipitation method. In this design of C/S/S structure, Er3+ is used as an energy collector in the first shell, which can reduce the energy loss by absorbing spontaneous emission from Yb3+. Then, by adding appropriate concentrations of Ce3+ into the same shell, the cross relaxation effect between Er3+ and Ce3+ is exploited to improve the efficiency of Er3+ in collecting the energy of spontaneous emission from Yb3+. During the upconversion (UC) process, Yb3+ plays a role as an energy transfer bridge, transferring the energy back to Er3+ in the core, thus enhancing the red UC emission intensity. Meanwhile, Tm3+ acts as an energy trapping center that contributes to the red emission. The results show that the spontaneous emission loss of Yb3+ has a certain effect on the UC fluorescence intensity, which will weaken the fluorescence to some extent, however is not the cause of the substantial decay of fluorescence. Therefore, this study provides clues for researchers to identify main factors affecting the luminescence efficiency, which will help develop more efficient UCNPs.
研究领域:
材料科学
·
光学
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY
·
2018
·Vol. 18
·期 12
·8207-8215
·
IF 1.354
Gong Guo,Xie Shaowen,Song Ya,Tan Haihu,Xu Jianxiong,Zhang Changfan,Xu Lijian
Well-defined and mono-dispersed lanthanide-ion-doped NaYF4 up-conversion nanoparticles (UCNPs) were synthesized via thermal decomposition using lanthanide oleate as the precursor. By rational selecting the dopant pairs of the doped lanthanide ions (Y3+, Yb3+,
Er3+ and Tm3+) with accurate molar ratios, three-primary-color (RGB) UCNPs which exhibited green (UCNPs-G), blue (UCNPs-B) and red (UCNPs-R) fluorescence, respectively, were prepared. The X-ray diffraction (XRD) patterns showed that the three UCNPs were purely hexagonal-phase
NaYF4 crystals. Transmission electron microscopy (TEM) images revealed that the synthesized UCNPs exhibited well-defined nanosphere morphology with uniform size distribution. The average diameters were 23.95±3.35 nm for UCNPs-G, 20.63±2.59 nm for UCNPs-B, and 19.24±2.37
nm for UCNPs-R, respectively. After surface modification employing polyacrylic acid (PAA) as modifier, the obtained UCNPs were converted to be hydrophilic, which can be used as fillers to construct luminescent polymer films and luminescent ink in anti-counterfeiting application.
研究领域:
材料科学
·
光学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ACS Nano
·
2019
·
IF 13.903
Jingwen Xu,Ning Liu,Di Wu,Zhida Gao,Yan-Yan Song,Patrik Schmuki
The low penetration depth of UV light in mammalian tissue is the critical limitation for the use of TiO2-based photocatalysis in biomedical applications. In this work, we develop an effective near-infrared (NIR)-active photocatalytic platform that consists of a shell structure of upconversion nanocrystals decorated on a core of Au/dark-TiO2. The heart of this system is the strong photocatalytic activity in the visible region enabled by the gold surface-plasmon resonance on dark TiO2 (D-TiO2). Simulation and experiment demonstrate for an optimized Au/D-TiO2 combination a highly enhanced light absorption in the visible range. Using ampicillin sodium (AMP) as model drug, we exemplify the effective use of this principle by demonstrating a NIR light-triggered photocatalytic payload release. Importantly, the photocatalytically generated reactive oxygen species can effectively inactivate AMP-resistant bacteria strains, thus maintaining an antibacterial effect even after all drug is released. Overall, we anticipate that the here-introduced NIR-light-active photocatalytic cascade can considerably widen TiO2-based photocatalysis and its applications into the infrared range.
研究领域:
材料科学
·
生物医学工程
·
微生物学
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产品关联
DOI
PubMed
高影响因子
JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2023
·
IF 9.9
Huazhen Liao,Song Ye,Peixuan Lin,Ling Pan,Deping Wang
The combination of upconversion nanoparticles (UCNPs) with porous zeolites could enable the development of multifunctional composites and extend their optical applications in sensing, detection and biomedical monitoring. Herein, a series of high luminescent UCNPs@Zeolites nano-micro composites were constructed via the in situ growth strategy, by taking the low phonon-energy fluoride nanoparticles of NaLnF 4 (Ln = Y, Gd) as doping hosts for Er 3+ /Yb 3+ , desilicated FAUY and ZSM-5 as the target zeolites. Benefiting from the formation of tightly combined interfaces between the UCNPs and the target zeolites that effectively passive the surface defects of UCNPs, three orders of magnitude of improved upconversion emission in maximum was obtained under 980 nm excitation through afterward heat treatment at 400 ℃. Moreover, the pre-exchange of Yb 3+ into target zeolites before the in situ growth of UCNPs is another feasible approach to drastically improve the upconversion emission intensity of the UCNPs@Zeolites nano-micro composites. By taking NaGdF 4 :Yb,Er@DSZSM-5/HT as an example probe, the detection of GA was demonstrated and the detection ability of which is super than that of the corresponding bare NaGdF 4 :Yb,Er UCNPs. This research provided a universal approach to construct the UCNPs@Zeolites nano-micro composites with varied upconversion emission colors simply by choosing activator ions, which therefore indicates wide potential applications.
研究领域:
材料科学
·
分析化学
·
生物医学工程
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Frontiers in Molecular Biosciences
·
2022
·
IF 6.113
Yaguchi Momo,Jia Xiaodan,Schlesinger Ramona,Jiang Xiue,Ataka Kenichi,Heberle Joachim
Direct optical activation of microbial rhodopsins in deep biological tissue suffers from ineffective light delivery because visible light is strongly scattered and absorbed. NIR light has deeper tissue penetration, but NIR-activation requires a transducer that converts NIR light into visible light in proximity to proteins of interest. Lanthanide-doped upconversion nanoparticles (UCNPs) are ideal transducer as they absorb near-infrared (NIR) light and emit visible light. Therefore, UCNP-assisted excitation of microbial rhodopsins with NIR light has been intensively studied by electrophysiology technique. While electrophysiology is a powerful method to test the functional performance of microbial rhodopsins, conformational changes associated with the NIR light illumination in the presence of UCNPs remain poorly understood. Since UCNPs have generally multiple emission peaks at different wavelengths, it is important to reveal if UCNP-generated visible light induces similar structural changes of microbial rhodopsins as conventional visible light illumination does. Here, we synthesize the lanthanide-doped UCNPs that convert NIR light to blue light. Using these NIR-to-blue UCNPs, we monitor the NIR-triggered conformational changes in sensory rhodopsin II from Natronomonas pharaonis (NpSRII), blue light-sensitive microbial rhodospsin, by FTIR spectroscopy. FTIR difference spectrum of NpSRII was recorded under two different excitation conditions: (ⅰ) with conventional blue light, (ⅱ) with UCNP-generated blue light upon NIR excitation. Both spectra display similar spectral features characteristic of the long-lived M photointermediate state during the photocycle of NpSRII. This study demonstrates that NIR-activation of NpSRII mediated by UCNPs takes place in a similar way to direct blue light activation of NpSRII.
研究领域:
生物物理学
·
光学
·
分子生物学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
CRYSTENGCOMM
·
2024
·Vol. 26
·期 27
·3603-3608
·
IF 2.6
Wenfei Xun,Zhipeng Meng,Chuwei Xie,Suli Wu
808 nm excited Nd3+ doped upconversion nanoparticles (UCNPs) have become a new research hotspot due to their reduced thermal effect when applied in a water-rich system. Different from Tm3+-mediated energy migration upconversion of Tb3+, in this work, NaYF4:Yb/Tb@NaYF4:Yb@NaNdF4:Yb@NaYF4 core–shell–shell–shell nanoparticles were designed based on the Yb3+ sensitized cooperative energy-transfer process to realize photon upconversion. NaYF4:Yb served as the migration layer, separating the activator Tb3+ from the sensitizer Nd3+ and minimizing the deleterious cross-relaxation between them. At 40% Yb3+ doping concentration in the NaYF4:Yb layer, bright green luminescence was achieved under 808 nm excitation. Meanwhile, the presence of Yb3+ in the sensitization layer (NaNdF4:Yb) reduced Nd3+ cross-relaxation, leading to improved energy migration efficiency of Nd3+ → Yb3+. Finally, the incorporation of an inert NaYF4 shell resulted in a significant luminescence boost. These nanoparticles can be dispersed in water after surface modification and could be effectively excited after laser penetration of 3 cm of water, indicating the enormous potential of the designed UCNPs in the biological system.
研究领域:
材料科学
·
生物医学工程
✓ 已验证
产品关联
DOI
高影响因子
CRYSTENGCOMM
·
2013
·Vol. 16
·期 10
·1859-1863
·
IF 3.879
Peiyu Qiu,Na Zhou,Yongnan Wang,Chunlei Zhang,Qing Wang,Rongjin Sun,Guo Gao,Daxiang Cui
Herein we report a novel cationic surfactant-assisted hydrothermal method to synthesize highly dispersed LuF3 upconversion nanoparticles (80–100 nm) and Na1.5Y2.5F9 flower-like assemblies (450–550 nm). Controlling the initial shape of the building blocks, growth oriented by the cationic surfactant and Ostwald ripening are deemed as the possible formation processes in the hydrothermal system.
研究领域:
材料科学
·
纳米技术
✓ 已验证
产品关联
DOI
高影响因子
Journal of Materials Chemistry C
·
2013
·Vol. 2
·期 11
·2037-2044
·
IF 0
Xuesong Zhai,Shusen Liu,Yongling Zhang,Guanshi Qin,Weiping Qin
Ultrasmall upconversion (UC) nanoparticles with intense luminescence are quite desirable for in vitro and in vivo bioimaging. Herein, we report the successful synthesis of sub-10 nm hexagonal NaTm0.02Lu0.98−xYbxF4 nanocrystals via a high boiling solvent process. The sizes and phases of the crystals can be finely tailored by tuning the amounts of the ligands used (octadecylamine and sodium oleate) and the temperature. The intensity of the UC emission of the nanocrystals increases as the the relative content of Yb3+ ions increases from 20% to 98%, owing to improved near-infrared absorption and energy-transfer from Yb3+ to Tm3+. The experimental results indicate that hexagonal NaYbF4 is the best host for ultrasmall Tm3+-doped UC nanoparticles and shows great potential in biomedical applications.
研究领域:
材料科学
·
生物医学工程
✓ 已验证
产品关联
DOI
Materials Science & Engineering C-Materials for Biological Applications
·
2016
·
IF 3.42
Huiqiong Yan,Xiuqiong Chen,Jia Shi,Zaifeng Shi,Wei Sun,Qiang Lin,Xianghui Wang,Zihao Dai
The rare earth ion doped upconversion nanoparticles (UCNPs) synthesized by hydrophobic organic ligands possess poor solubility and low fluorescence quantum yield in aqueous media. To conquer this issue, NaYF 4 :Yb 3 + /Tm 3 + UCNPs, synthesized by a hydrothermal method, were coated with F127 and then assembled with chitosan to fabricate the chitosan/NaYF 4 :Yb 3 + /Tm 3 + composite beads (CS/NaYF 4 :Yb 3 + /Tm 3 + CBs) by Pickering emulsion system. The characterization results revealed that the as-synthesized NaYF 4 :Yb 3 + /Tm 3 + UCNPs with an average size of 20 nm exhibited spherical morphology, high crystallinity and characteristic emission upconversion fluorescence with an overall blue color output. The NaYF 4 :Yb 3 + /Tm 3 + UCNPs were successfully conjugated on the surface of chitosan beads by the gelling of emulsion droplets. The resultant CS/NaYF 4 :Yb 3 + /Tm 3 + CBs showed good upconversion luminescent property, drug-loading capacity, release performance and excellent biocompatibility, exhibiting great potentials in targeted drug delivery and tissue engineering with potential tracking capability and lasting release performance.
研究领域:
材料科学
·
生物医学工程
·
药物递送
✓ 已验证
产品关联
DOI
PubMed
高影响因子
CHINESE JOURNAL OF CATALYSIS
·
2018
·
IF 3.525
Mengli Zhao,Wanni Wang,Chenxi Huang,Wang Dong,Yang Wang,Sheng Cheng,Huiqing Wang,Haisheng Qian
Photocatalysis driven by near-infrared (NIR) light is of scientific and technological interest for exploiting solar energy. In this study, we demonstrate a facile hydrothermal process to synthesize core-shell nanoparticles combining upconversion nanoparticles (UCNPs) and alloyed Zn x Cd 1- x S, which can be excited using NIR or visible light. Morphologies, phase, and chemical composition have been investigated using field-emission scanning electron microscopy, transmission electron microscopy, X-ray diffraction analysis, and atomic absorption spectroscopy. Moreover, we found that amorphous TiO 2 layers existing in the final samples play an important role in formation of UCNPs@Zn x Cd 1- x S yolk-shell nanoparticles, which bind the as-prepared Zn x Cd 1- x S nanoparticles tightly to form yolk-shell nanoparticles. The chemical composition of alloyed Zn x Cd 1- x S can be tunable by adjusting the amount of the Cd and Zn source compounds. The photochemical reduction of Cr(VI) in water has been performed to study the photocatalytic performance under irradiation by NIR light or a simulated solar light, showing efficient photoreduction and Cr(VI) removal over the as-prepared UCNPs@Zn x Cd 1- x S/TiO 2 yolk-shell nanoparticles. The as-prepared UCNPs@Zn x Cd 1- x S/TiO 2 nanoparticles show excellent production of hydroxyl radicals, which are responsible for the photochemical reduction of Cr(VI) to Cr(III). This study will provide an alternative strategy for environmental wastewater treatment , making full use of solar energy.
研究领域:
环境科学
·
材料科学
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）