INTERNATIONAL JOURNAL OF CHEMICAL KINETICS
·
2024
·Vol. 56
·期 10
·596-612
·
IF 1.5
Xue-qi Zhang,Qing-xian Yue,Rui Ding,Jie Liu
Corrosion protection of steel bars in alkaline concrete environments poses a common challenge in marine engineering. One approach to mitigate steel bar corrosion is the addition of corrosion inhibitors to the concrete. In alkaline environments, the passivation of rebars occurs through anodic passivation coupled with the cathodic oxygen reduction reaction (ORR). The catalysis of ORR can expedite anode passivation. To investigate the corrosion inhibition of steel bars in alkaline environments, meso-tetra(4-carboxyphenyl)porphine (TCPP), known for its ORR catalytic properties, is selected. TCPP forms adsorption films on the surface of steel bars, facilitating the formation of passivation films. TCPP primarily adsorbs onto active sites on the surface of the passivation film, where lattice iron ions have leached. The adsorbed TCPP accelerates the formation of the passivation film through ORR catalysis, inhibiting the development of passivation film defects and enhancing the integrity and protection of the passivation film. The most significant effect is observed when the concentration of TCPP is 0.5 mmol/L. The physical adsorption of TCPP is primarily determined by the negative charge centers, namely the carboxyl group O and the pyrrole N. However, due to steric hindrance caused by the unrestricted rotation of the carboxyl benzene, the pyrrole N does not play a dominant role in chemical adsorption. Instead, the active site for chemical adsorption is the carboxyl group O. The adsorption process significantly reduces the diffusion coefficient of TCPP molecules, providing a robust and stable adsorption binding. Phthalocyanine molecules without carboxyl benzene groups adopt a planar structure, allowing them to form stable adsorption configurations on the iron surface through flat adsorption. This observation provides guidance for the design of novel metal phthalocyanine molecules. Specifically, the development of metal phthalocyanine molecules with modifying groups that are coplanar with the phthalocyanine ring and possess restricted rotation can achieve flat adsorption, improve coverage rate, and enhance adsorption configuration stability.
研究领域:
材料科学
·
腐蚀工程
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DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2025
·
IF 13.2
Yizhou Tu,Liqin Han,Xiaolu Ding,Xingqi Zhu,Guizhou Xu,Xianchuan Xie,Qing Zhou,Chendong Shuang,Aimin Li
Refractory pharmaceuticals and personal care products (PPCPs) represented by diclofenac, ibuprofen, sulfamethoxazole, and carbamazepine have become risk compounds in municipal wastewater, and they possessed generalized antimicrobial properties along with numerous electron-withdrawing groups, difficult to biodegrade through bacterial-based systems. In contrast, fungi could thrive even in environments contaminated by antibiotics, among which the white rot fungus Trametes versicolor ( T. versicolor ) possessed enzymatic degradation systems represented by laccase, capable of degrading complex chemical bonds. However, almost all white rot fungi reactors were conducted at pH 4.5, which limited their application. In this study, the neutral degradation environment was developed for T. versicolor , and the pH-dominated laccase degradation mechanism was clarified. It was found that T. versicolor could possess both laccase activity and production at pH 6.5, with better application potential compared to acidic conditions. Accordingly, fluidized bed T. versicolor reactors were developed, and their application potential under neutral pH was validated for the first time in municipal wastewater. Compared with reactors without any adjustment, the four refractory PPCPs removal by T. versicolor reactors was increased from 26% to 72%, and T. versicolor abundance was increased from almost zero to 27% by adding carbon and nitrogen sources and adjusting pH to 6.5. Metabolic pathway analysis revealed the cytochrome P450 and amide hydrolase functional genes of T. versicolor , which were critical for PPCPs degradation. Nine transformation products of PPCPs were identified, further validating the multiple capabilities of T. versicolor for both hydroxylation and complex chemical structures (carbon–nitrogen bonds, epoxides, carbon–sulfur bonds) degradation. Furthermore, these findings also provided new ideas for the degradation of more complex aminobenzene or chlorinated aniline wastewater.
研究领域:
环境科学
·
微生物学
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产品关联
DOI
高影响因子
POLYMER
·
2021
·
IF 4.43
Yongjie Dong,Siqi Chen,Piao Ning,Ka Lu,Song Ma,Yingjie Wang,Shaoyu Lü
Self-healing hydrogels based on phenylboronate ester bonds are of huge interest in polymer science. However, most of these hydrogels only heal themselves at pH above their pKa (mostly > 8.0), which reduces their potential application in physiologic environments. Here, we showed that a small amount of phosphate produced stable hydrogels, able to support their self-healing at neutral pH. The hydrogel was formed by poly (3-acryloxymethylphenylboronic acid- co -N, N-dimethyl acrylamide) and poly (D-gluconamidoethyl methacrylate- co -N, N-dimethyl acrylamide) in phosphate buffer. Self-healing was observed at pH = 7.0. Intermolecular interactions between phenylboronic acid and phosphate were suggested by rheology, DSC determination and QTAIM calculations. The study represents a new mechanism to promote phenylboronate-based hydrogel formation and self-healing at neutral environment and, more importantly, provides considerable insight into their application in physiologic conditions including sensors and tissue engineering.
研究领域:
材料科学
·
生物医学工程
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产品关联
DOI
高影响因子
ACS Applied Nano Materials
·
2021
·
IF 5.097
Jin Wang,Yi Wang,Dun Zhang,Chao Chen,Zhanxu Yang
Harvesting a remarkable antibacterial performance is a major point to choose enzymatic catalytic and photocatalytic coupling catalysts. Here, Co–Mo–S mixed metal sulfides (MMSs) were composed by tailoring the composition and energy of metal organic framework (MOF)-based precursors. When n(Co)/n(Mo) = 1:1, Co/Mo-MOF is in the lowest energy state and the vulcanized CoS2/MoS2 nanosheets (NSs) exhibit the best enzymatic property. With the inherent photocatalytic activity, CoS2/MoS2 NSs can degrade more than 90% of methylene blue, methyl orange, rhodamine B, and tetracycline hydrochloride within 1 h. Promoted by intrinsic photocatalytic properties, CoS2/MoS2 NSs exhibit outstanding mimic enzyme-mimicking abilities in a neutral medium, which solve the big problem that nanozymes can only work in acidic environments. Due to the collaboration of enzymatic and photocatalytic catalysis, ·O2– can be generated in a neutral, no H2O2, and dark system, which can effectively kill Escherichia coli and Staphylococcus aureus. In all, the design of MOFs with adjustable compositions, the breakthrough of enzymatic catalysis working in a neutral medium, and the innovation of sterilization independent of external conditions encourage the utilization in an open environment and the construction of multifunctional materials in biotechnology, biosensors, and biomedicine.
研究领域:
材料科学
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生物医学
·
环境科学
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产品关联
DOI
高影响因子
TALANTA
·
2019
·
IF 4.916
Wang Xu,Jian-Fang Cao,Yao-Yao Zhang,Yang Shu,Jian-Hua Wang
Boronate affinity is widely used for the isolation of glycoproteins at alkaline conditions. For further proteomic studies, however, it is of highly importance to perform protein adsorption in neutral medium. For this purpose, we report a novel composite material, i.e., 4-carboxyphenylboronic acid (CPBA) functionalized nickel-substituted polyoxometalate [Ni 6 (en) 3 (Tris)(H 2 O) 2 (PW 9 O 34 )]•nH 2 O (Ni 6 PW 9 )-sodium alginate (SA) hybrid. The abundant oxygen atoms in the hybrid (shortly termed as CPBA-Ni 6 PW 9 /SA) significantly reduce the pKa value of CPBA moiety, which well facilitates the selective adsorption of glycoproteins at neutral environment (at pH 7.0). The moiety of sodium alginate (SA) in the hybrid further improves the isolation/enrichment capacity for glycoproteins through hydrophilic interaction . The adsorption efficiency of Immunoglobulin G (IgG, 1.0 mL, 100 μg mL −1 ) by 1.0 mg CPBA-Ni 6 PW 9 /SA hybrid reaches up to 91%, and 1.0 mL of Tris-HCl buffer (100 mmol L −1 ) provides an elution efficiency of 82%. The adsorption behavior of IgG fits Langmuir adsorption model, offering a maximum adsorption capacity of 495 mg g −1 . The CPBA-Ni 6 PW 9 /SA hybrid is practically applied for the enrichment of glycoproteins from human serum. SDS-PAGE assay result indicates that approximately 92% serum albumin is eliminated and high-purity IgG is obtained. Liquid chromatography-tandem mass spectrometry (LC-MS/MS) analysis clearly demonstrated that after enriching with CPBA-Ni 6 PW 9 /SA, 81 glycoproteins are identified and 79.4% recognition selectivity is achieved.
研究领域:
生物化学
·
蛋白质组学
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产品关联
DOI
PubMed
高影响因子
INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
·
2025
·
IF 8.3
Yaoze Wang,Guangfei Qu,Yun Zhang,Linjin Li,Jun Wang,Ping Lu,Yuanchuan Ren,Minhua Cheng,Yingying Cai,Junyan Li
The chlorine evolution reaction (CER) is a critical process in the chlor-alkali industry. However, the electrocatalytic activity and selectivity of non-precious metal-based catalysts in CER remain unsatisfactory, posing a significant challenge to the development of efficient and economical CER electrocatalysts. In this study, a CuMnRu/CC electrode containing a low Ru content (0.0356 wt%) was successfully synthesized via a simple thermal decomposition method. In a 2 M NaCl solution (pH = 7), this electrode achieved a current density of 99.8 mA cm −2 at an applied potential of 1.84 V (vs. RHE), which significantly exceeded the performance of traditional DSA electrodes (31.3 mA cm −2 ), with a Faradaic efficiency of 94.67%. Additionally, the CuMnRu/CC electrode exhibited exceptional durability and stability in a 100-h stability test, showing only a marginal increase in potential. Furthermore, DFT calculations demonstrated that ruthenium doping improved the electronic structure and facilitated electron transfer, reducing the reaction energy barriers during the electrocatalytic chlorine evolution reaction (CER) on the CuMnRu/CC electrode, which led to a considerable enhancement in the overall catalytic performance. In summary, the CuMnRu/CC electrode exhibits not only highly efficient CER catalytic activity but also notable economic and stability benefits, offering a promising electrode material for the chlor-alkali industry.
研究领域:
材料科学
·
电化学
·
工业化学
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产品关联
DOI
高影响因子
Polymer Chemistry
·
2018
·Vol. 9
·期 42
·5242-5247
·
IF 4.927
Jinhu Wang,Guolu Ma,Wei Huang,Yi He
Mussel-inspired polydopamine (PDA) coating is a promising avenue for surface modification. However, the reported methods for PDA deposition require alkaline media, strong oxidation reagents or UV light irradiation. Herein, we report a facile and mild method to prepare PDA in the presence of 9-mesityl-10-methylacridinium ions (Acr+-Mes) as the photocatalyst under visible-light irradiation. The excited-state Acr+-Mes with a high oxidation property and its intermediate which can activate dissolved oxygen enable the oxidation polymerization of dopamine in a neutral environment (pH = 7.0). This approach is easily controlled by switching the visible light (ON/OFF possibility), which can be used to coat several substrates such as polystyrene foam, filter paper, aluminium foil, and glass as well as improve their hydrophilicity. In addition, a visual colorimetric assay is developed for detection of bovine serum albumin. This assay is based on the fact that protein with diverse functional groups serves as the anchor point for PDA deposition that further promotes the oxidation of dopamine, giving rise to a distinct UV-vis absorption change.
研究领域:
材料科学
·
化学
·
生物材料
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产品关联
DOI
高影响因子
RSC Advances
·
2016
·Vol. 6
·期 89
·86455-86463
·
IF 3.289
Xue Qu,Feifei Wang,Yi Sun,Yu Tian,Rui Chen,Xiaoyu Ma,Changsheng Liu
Glycoproteins play important roles in various biological events. Extraction of specific bioactive glycoproteins from physiological fluids is highly required for clinical diagnosis and treatment. Concanavalin A (Con A) is a tetramer lectin protein that can specifically bind glycospecies containing sugar units, and this binding occurs in physiological environments. Inspired by this, we propose a sugar–lectin recognition based glycoprotein surface imprint, which is anticipated to selectively extract bioactive glycoproteins in physiological environments. The glycosylated biomarker, transferrin, was used as a model template. Transferrin was first immobilized on a Con A modified Fe3O4 surface via the sugar–lectin interaction at pH 7.4. Dopamine was then polymerized onto this surface for glycoprotein imprinting at the same pH, and continuous oxygen bubbling into the dopamine solution improved the polymerization speed. After removal of the template by boronate buffer, transferrin imprinted Fe3O4 was obtained. The subsequent binding experiment indicated that the transferrin imprint has pH dependent binding affinity towards this protein. The optimal transferrin binding capacity, as well as the maximum imprinting factor was observed at neutral pH. The isotherm adsorption study reveals that imprinted and non-imprinted material are both fitted with the Langmuir adsorption model. Single selective adsorption and competitive adsorption experiments show that the obtained surface imprint has selectivity towards template glycoprotein, and circular dichroism (CD) spectral analysis indicates that boronate buffer washing has no negative influence on the natural structure of transferrin and Con A. These results demonstrate that this novel glycoprotein surface imprint can work under physiological conditions, and the glycoprotein extraction method is mild enough to keep the bioactivity of these targets for further bio-application.
研究领域:
生物化学
·
分子生物学
·
生物技术
·
临床诊断
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产品关联
DOI
高影响因子
Discover Nano
·
2025
·Vol. 20
·期 1
·1-17
·
IF 4.5
Hu Dongmei,Wu Qing,Yang Yujun,Wang Yan,Li Yanhao,Chen Haixiang,Tang Liang,Mao Xiang,Wang Zhenyu
Metal-based nanoenzymes with excellent biocompatibility and stable chemical properties are an effective antimicrobial agent against bacterial resistance due to their radical-mediated catalysis. In this work, due to the pH of most bacterial infection sites being close to neutral, targeting the problem of Fe 3 O 4 @Ag difficulty in maintaining the catalytic activity of nanoenzymes in neutral environments, we prepare a novel multifunctional Fe 3 O 4 @Ag@ indocyanine green/adenosine triphosphate peroxidase nanoenzymes for synergistic antibacterial activity. ICG (Indocyanine Green) and ATP (Adenosine triphosphate) are adsorbed on the surface of Fe 3 O 4 @Ag through electrostatic adsorption to form its structure. The cell viability remained above 90%, indicating its good biocompatibility. By complexing ATP with nanoenzymes to participate in single electron transfer and binding with Fe (II), ATP promotes the sudden release of hydroxyl radical (·OH) from the system, successfully transferring Fe 3 O 4 @Ag the peroxidase activity of nanoenzymes extends to neutral pH. By utilizing ICG as a photosensitizer and a sonosensitizer, under the combined treatment of near-infrared light and ultrasound, the photodynamic therapy (PDT)/photothermal therapy (PTT)/sonodynamic therapy (SDT) functions can be achieved, achieving multifunctional synergistic antibacterial effects. In a neutral environment, its bactericidal efficiency against Gram negative ( Escherichia coli ) and Gram positive ( Staphylococcus aureus ) is 99.9% and 99.7%, respectively, providing a new multi-mode synergistic antibacterial strategy for bacterial infections. Graphical abstract Metal based nanoenzymes with excellent biocompatibility and stable chemical properties are an effective antimicrobial agent against bacterial resistance due to their radical mediated catalysis. The prepared multifunctional Fe 3 O 4 @Ag@ICG/ATP exhibit peroxidase nanoenzymes perform ance for synergistic antibacterial activity. ICG and ATP are adsorbed on the surface of Fe 3 O 4 @Ag through electrostatic adsorption to form its structure
研究领域:
生物医学工程
·
纳米医学
·
抗菌材料研究
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产品关联
DOI
PubMed
高影响因子
Chemistry-An Asian Journal
·
2022
·Vol. 17
·期 16
·e202200296
·
IF 4.839
Xinyu Jin,Hongxia Zhao,Zhicong Chao,Xiaofeng Wang,Qing Zhang,Huangxian Ju,Ying Liu
Graphical CuO nanoclusters (CuO NC) with a porous structure were synthesized by self-assembly of oleylamine-stabilized CuO NPs (OAm−CuO NPs), and functionalized with folic acid (CuO NC-FA) for specific HeLa cell targeting. Due to the large surface area, CuO NC-FA demonstrated efficient intracellular Fenton-like reaction efficiency with good cell killing capability. Chemodynamic therapy (CDT) based on Fenton and Fenton-like reactions induces cancer cell killing via in situ catalyzing H 2 O 2 and generating highly oxidative hydroxyl radicals (⋅OH) in tumor sites. Their application is not limited by tumor grown depth or hypoxic microenvironment. However, the reaction efficiency is still hampered due to the structure of catalytic agents and the requirement for low pH environment. Here, we design a porous CuO nanocluster (CuO NC) through self-assembly of oleylamine stabilized CuO NPs (OAm−CuO NPs), and functionalize it with folic acid (CuO NC-FA) for specific tumor cell targeting. It can catalyze H 2 O 2 with high efficiency in nearly neutral environment. Besides, the porous structure of CuO NC also helps the diffusion of H 2 O 2 to the interior of nanocluster to further improve Fenton-like reaction efficiency. The convenient synthesis of CuO NC-FA with good Fenton-like reaction efficiency at neutral environment demonstrates good chemodynamic therapy effect.
研究领域:
纳米技术
·
癌症研究
·
材料科学
·
生物医学工程
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产品关联
DOI
PubMed
高影响因子
ACS Nano
·
2019
·
IF 13.903
Xiaoyu Mu,Junying Wang,Yonghui Li,Fujuan Xu,Wei Long,Lufei Ouyang,Haile Liu,Yaqi Jing,Jingya Wang,Haitao Dai,Qiang Liu,Yuanming Sun,Changlong Liu,Xiao-Dong Zhang
Metal nanozyme has attracted wide interest for biomedicine, and a highly catalytic material in the physiological environment is highly desired. However, catalytic selectivity of nanozyme is still highly challenging, limiting its wide application. Here, we show a trimetallic (triM) nanozyme with highly catalytic activity and environmental selectivity. Enzyme-mimicked investigations find that the triM system possesses multi-enzyme-mimetic activity for removing reactive oxygen species (ROS) and reactive nitrogen species (RNS), such as 1O2, H2O2, •OH, and •NO. Importantly, triM nanozyme exhibits the significant neutral environment preference for removing the •OH, 1O2, and •NO free radical, indicating its highly catalytic selectivity. The density functional theory (DFT) calculations reveal that triM nanozyme can capture electrons very easily and provides more attraction to reactive oxygen and nitrogen species (RONS) radicals in the neutral environment. In vitro experiments show that triM nanozyme can improve the viability of injured neural cell. In the LPS-induced brain injury model, the superoxide dismutase (SOD) activity and lipid peroxidation can be greatly recovered after triM nanozyme treatment. Moreover, the triM nanozyme treatment can significantly improve the survival rate, neuroinflammation, and reference memory of injured mice. Present work provides a feasible route for improving selectivity of nanozyme in the physiological environment as well as exploring potential applications in brain science.
研究领域:
生物医学工程
·
纳米技术
·
神经科学
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产品关联
DOI
PubMed
高影响因子
Nano Research
·
2024
·
IF 9.5
Liu Dong-Xue,Deng Xin,Zhu Yong-Fu,Meng Zhe,Sun Xue-Feng,Shi Miao-Miao,Zhong Hai-Xia,Yan Jun-Min
Electrocatalytic reduction of nitrate \(({\rm{N}}{{\rm{O}}_3}^ - )\) and nitride \(({\rm{N}}{{\rm{O}}_2}^ - )\) to ammonia (NH 3 ) is of wide interest as a promising alternative to the energy-intensive Haber-Bosch route for mitigating the vast energy consumption and the accompanied carbon dioxide emission, as well as benefiting for the relevant sewage treatment. However, exploring an efficient and low-cost catalyst with high atomic utilization that can effectively facilitate the slow multi-electron transfer process remains a grand challenge. Herein, we present an efficient hydrogenation of \({\rm{N}}{{\rm{O}}_3}^ - /{\rm{N}}{{\rm{O}}_2}^ - \) species to NH 3 in both alkaline and neutral environments over the Fe 2 (MoO 4 ) 3 derived hybrid electrocatalyst with the metallic Fe site on FeMoO 4 (Fe/FeMoO 4 ). The Mo ingredient can play a synergistically positive role in further promoting the NH 3 production on Fe. As a result, Fe/FeMoO 4 behaves well in the electrochemical NH 3 generation from \({\rm{N}}{{\rm{O}}_2}^ - \) with a maximum NH 3 Faradaic efficiency (FE) of 96.53% and 87.68% in alkaline and neutral electrolyte, corresponding to the NH 3 yield rate of 640.68 and 302.56 \({\rm{mg}} \cdot {{\rm{h}}^{ - 1}} \cdot {\rm{m}}{{\rm{g}}_{{\rm{cat}}.}}^{ - 1}\) , respectively, which outperforms the Fe and Mo counterpart and other similar catalyst, showing the robust catalytic capacity of each active site.
研究领域:
催化
·
电化学
·
环境科学
·
材料科学
✓ 已验证
DOI
高影响因子
危险品化学品经营许可证（带存储）