Gels
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2022
·Vol. 8
·期 8
·475
·
IF 4.432
Chengdi Huang,Hanwei Zhang,Ziqing Hu,Youping Zhang,Xiaofan Ji
Polymer gels have been widely used in the field for tissue engineering, sensing, and drug delivery due to their excellent biocompatibility, hydrophilicity, and degradability. However, common polymer gels are easily deformed on account of their relatively weak mechanical properties, thereby hindering their application fields, as well as shortening their service life. The incorporation of reversible non-covalent bonds is capable of improving the mechanical properties of polymer gels. Thus, here, a poly(methyl methacrylate) polymer network was prepared by introducing host–guest interactions between pillar[5]arene and pyridine cation. Owing to the incorporated host–guest interactions, the modified polymer gels exhibited extraordinary mechanical properties according to the results of the tensile tests. In addition, the influence of the host–guest interaction on the mechanical properties of the gels was also proved by rheological experiments and swelling experiments.Keywords:polymer gels;host–guest interactions;mechanical performance;pillar[5]arene
研究领域:
材料科学
·
化学
·
生物材料
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产品关联
DOI
PubMed
高影响因子
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
·
2023
·Vol. 415
·期 18
·4343-4352
·
IF 4.3
Liu Min,Wang Simin,Ge Wuxia,Bi Wentao,Chen David Da Yong
To systematically study the influence of host–guest interactions on the analytical performance of direct analysis in real time mass spectrometry (DART-MS), the interactions between cyclodextrins (CDs) and different Sudan dyes were investigated. The results showed that the host–guest interaction between CDs and Sudan dyes did not affect qualitative analysis of the target compounds, but led to a lower signal intensity for Sudan dyes, thus affecting quantitative analysis of the target compounds. The stronger the host–guest interaction, the weaker the signal intensity of target compound on DART-MS. The results also show that both in solution and in solid-phase microextraction (SPME), the addition of organic solvents can weaken the host–guest interaction between CDs and Sudan dyes, thus improving the signal intensity in DART-MS. In SPME, adding organic solvents has a certain practical value and can improve the efficiency of Sudan dye analysis. This study suggests that appropriate sample pretreatment is needed to weaken noncovalent interactions prior to DART-MS analysis to obtain more accurate quantitative results. The data provide some insight into the effects of other noncovalent interactions on the efficiency of DART-MS as an analytical tool, as well as the potential to study intermolecular interactions with DART-MS. Graphical Abstract
研究领域:
分析化学
·
质谱分析
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DOI
PubMed
高影响因子
PHYSICAL CHEMISTRY CHEMICAL PHYSICS
·
2012
·Vol. 14
·期 17
·6119-6125
·
IF 3.573
Zhaolai Chen,Jing Li,Xue Zhang,Zhennan Wu,Hao Zhang,Haizhu Sun,Bai Yang
Creation of nanoparticle (NP) architectures via a self-assembly strategy is the current means to integrate and/or modulate the functionalities of NPs. In this paper, we demonstrate the capability for constructing NP spherical superstructures through the specific interaction between host and guest molecules, for instance the model system of α-cyclodextrin (α-CD) and oleic acid (OA), which are decorated on two different NPs beforehand. Subsequently, the OA-decorated hydrophobic NPs are dispersed in hexane, whereas the α-CD-decorated NPs are dispersed in water. The blending of these two immiscible solutions produces NP binary superstructures because of the multiple linkages between the α-CD- and OA-decorated NPs. Control experiments indicate that the self-assembly of NPs occurs either at the hexane/water interface to form hybrid films or in the aqueous phase to generate spherical architectures, which strongly depends on the amount and the size of α-CD-decorated NPs. The high ratio and small size of the α-CD-decorated NPs facilitate the formation of spherical architectures. Competitive experiments with the addition of host α-CD and guest sodium oleate clearly confirm that the main driving force for the NP co-assembly is the specific interaction between α-CD and OA. In addition, the flexible decoration of α-CD and OA on the NPs makes the current strategy generally applicable for a variety of NPs, such as the superstructures of Au/Fe3O4, Pt/Fe3O4, and Au/NaYF4:Yb,Tm, which is expected to promote the further application of NPs in environmental and biological sciences.
研究领域:
材料科学
·
生物学
·
纳米技术
✓ 已验证
DOI
高影响因子
INORGANIC CHEMISTRY COMMUNICATIONS
·
2019
·
IF 1.795
Mei-Xiang Yang,Ming Liu,Mei Yang,Qin Wang,Xi Zeng,Zhu Tao,Xin Xiao,Ying Huang
In the present work, a well-known host–guest inclusion complex comprising a cucurbit[7]uril (Q[7]) and an important biological dye, Hoechst-33258 (H33258) was selected as a fluorescence probe. In contrast to the pH conditions in which H33258 is exhibited in the literature, these being, mono- or di-protonated states, in the present work, we selected an extreme case, whereby H33258 was displayed in an anionic state (pH = 11). The investigation of the host–guest interaction demonstrated similar inclusion modes in a wide pH range, that is the dumbbell-like inclusion complex in which one Q[7] includes piperazine moiety and another Q[7] includes the phenol moiety of H33258. Moreover, investigation on the binding capacity of the 15 selected anions under three representative pH levels (pH = 2, pH = 4.5 and pH = 11, respectively) indicated that the H33258@Q[7] probe displayed unique selectivity on HPO 4 2 − anion in medium at pH = 11. More importantly, the probe could open a new platform in Q[ n ]-chemistry, that is the Q[ n ]-based host–guest interaction systems can apply in anion recognition or response.
研究领域:
化学
·
生物化学
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产品关联
DOI
高影响因子
Polymers
·
2023
·Vol. 15
·期 19
·4024
·
IF 5
Lixia Huang,Yifei Jiang,Xinying Chen,Wenqi Zhang,Qiuchen Luo,Siyan Chen,Shuhan Wang,Fangqing Weng,Lin Xiao
Supramolecular responsive microcarriers based on chitosan microspheres were prepared and applied for nonenzymatic cell detachment. Briefly, chitosan microspheres (CSMs) were first prepared by an emulsion crosslinking approach, the surface of which was then modified with β-cyclodextrin (β-CD) by chemical grafting. Subsequently, gelatin was attached onto the surface of the CSMs via the host–guest interaction between β-CD groups and aromatic residues in gelatin. The resultant microspheres were denoted CSM-g-CD-Gel. Due to their superior biocompatibility and gelatin niches, CSM-g-CD-Gel microspheres can be used as effective microcarriers for cell attachment and expansion. L-02, a human fetal hepatocyte line, was used to evaluate cell attachment and expansion with these microcarriers. After incubation for 48 h, the cells attached and expanded to cover the entire surface of microcarriers. Moreover, with the addition of adamantane (AD), cells can be detached from the microcarriers together with gelatin because of the competitive binding between β-CD and AD. Overall, these supramolecular responsive microcarriers could effectively support cell expansion and achieve nonenzymatic cell detachment and may be potentially reusable with a new cycle of gelatin attachment and detachment.Keywords:chitosan;microcarrier;cell culture;cell detachment;host–guest interaction
研究领域:
生物材料
·
细胞工程
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DOI
PubMed
高影响因子
MACROMOLECULES
·
2017
·
IF 5.835
Yan Wang,Ming-Zhe Lv,Nan Song,Zeng-Jie Liu,Chunyu Wang,Ying-Wei Yang
We report a new strategy to construct a multi-stimuli-responsive fluorescent supramolecular polymer by the strong host–guest interactions between a diselenium bond-bridged pillar[5]arene dimer and an AIE-active tetraphenylethylene (TPE)-containing neutral guest bearing two imidazole terminal binding sites. The resulting supramolecular polymer shows a remarkable fluorescence emission decrease at low concentration. Significantly, the diselenium bonds introduced into the supramolecular polymer serve as redox-responsive building blocks. Upon addition of reductants, the supramolecular polymer depolymerized owing to the cleavage of the covalent diselenium bonds in the system. On the other hand, competitive guests such as adiponitrile, which bind strongly with pillar[5]arenes, could lead the disassembly of the polymer to oligomers without breaking any covalent bonds in the system. These two types of depolymerization approaches can both result in the fluorescence intensity recovery of the system to a certain extent, which will hopefully enrich the methodology toward the construction of smart supramolecular polymeric materials with different properties.
研究领域:
超分子化学
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材料科学
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有机化学
✓ 已验证
DOI
高影响因子
JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2016
·
IF 3.782
Guangyu Li,Zhirui Dong,Yuting Zhu,Weijun Tong,Changyou Gao
Colloidal microcapsules (MCs) have received considerable attention in the fields of microencapsulation , drug delivery as well as microreactors due to their unique nanoparticles-composed structure. In this study, dual-responsive colloidal MCs based on host-guest interaction were successfully fabricated via a layer-by-layer assembly method on sacrificial solid templates. Ferrocene-modified polyethylenimine (PEI-Fc) and cyclodextrin-modified polystyrene nanoparticles (PS-CD NPs) were used as building blocks for assembly. The colloidal MCs could be disassembled into nano-components upon addition of competitive adamantane (Ad) molecules or in the solution with a pH lower than 4.
研究领域:
材料科学
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药物递送
·
纳米技术
✓ 已验证
产品关联
DOI
PubMed
高影响因子
INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
·
2016
·
IF 2.567
Wan-Fen Pu,Yang Yang,Bing Wei,Cheng-Dong Yuan
In this work, a novel enhanced oil recovery (EOR) copolymer, which is expected to be an alternative to currently used polymers, was successfully synthesized through free radical micellar copolymerization of acrylamide, acrylic acid, 6-acrylamide-β-cyclodextrin (N-β-CD), and acrylamide-adamantane (N-ADA). The copolymer was characterized by Fourier transform infrared spectroscopy, 1H nuclear magnetic resonance spectroscopy, thermal gravimetric analysis, and scanning electron microscopy. The results demonstrated that because of the incorporation of ADA and β-CD groups, host–guest interactions occurred in the aqueous solution, which subsequently improved the salt tolerance, temperature resistance, shear resistance, and viscoelastic properties of the synthesized polymer. Regarding the EOR performance, it was observed that 8.58% incremental oil was produced using this polymer after water flooding was exhausted. The superior properties make this novel polymer promising in enhancing oil recovery, particularly for reservoirs which have discarded polymer flooding techniques because of harsh conditions.
研究领域:
石油工程
·
高分子化学
✓ 已验证
产品关联
DOI
高影响因子
PLoS One
·
2013
·Vol. 8
·期 6
·e64722
·
IF 3.73
Fei Wang,Naimin Shao,Yiyun Cheng
In this study, the host-guest behavior of poly(amidoamine) (PAMAM) dendrimers bearing amine, hydroxyl, or carboxylate surface functionalities were investigated by paramagnetic NMR studies. 2,2,6,6-Tetramethylpiperidinyloxy (TEMPO) derivatives were used as paramagnetic guest molecules. The results showed that TEMPO-COOH significantly broaden the 1 H NMR peaks of amine- and hydroxyl-terminated PAMAM dendrimers. In comparison, no paramagnetic relaxation enhancement (PRE) was observed between TEMPO-NH 2 , TEMPO-OH and the three types of PAMAM dendrimers. The PRE phenomenon observed is correlated with the encapsulation of TEMPO-COOH within dendrimer pockets. Protonation of the tertiary amine groups within PAMAM dendrimers plays an important role during this process. Interestingly, the absence of TEMPO-COOH encapsulation within carboxylate-terminated PAMAM dendrimer is observed due to the repulsion of TEMPO-COO- anion and anionic dendrimer surface. The combination of paramagnetic probes and 1 H NMR linewidth analysis can be used as a powerful tool in the analysis of dendrimer-based host-guest systems.
研究领域:
化学
·
材料科学
·
生物物理学
✓ 已验证
DOI
PubMed
高影响因子
JOURNAL OF APPLIED POLYMER SCIENCE
·
2024
·Vol. 141
·期 16
·e55264
·
IF 2.7
Yizhe Liu,Yang Wu,Kai Feng,Hui Liu,Chenxi Qin,Meirong Cai,Xiaowei Pei,Feng Zhou
In this work, a hydrophobic guest monomer containing adamant end-group was synthesized and introduced into the acrylamide hydrogel system to prepare macroscopic guest hydrogel. The swelling, transparency, and mechanical properties of the guest hydrogels can be significantly changed by soaking the guest hydrogel into hydrophilic cyclodextrin solution because the hydrophobic guest groups were recognized and covered by the hydrophilic host molecules. In addition, the surface lubrication property could be adjusted by changing the proportion of acrylamide and adamantane monomers in the hydrogel system. More importantly, cyclodextrin can bind with adamantane through host-guest interactions, enabling the adjustment of the hydrophilicity/hydrophobicity properties of the hydrogel system. By controlling the assembly time, the hydrogel with different lubrication behaviors can be obtained. The controllable surface friction that this specific binding of host-guest interaction has broad application prospects in intelligent device, bionic lubrication and other fields.
研究领域:
材料科学
·
生物医学工程
·
化学工程
✓ 已验证
产品关联
DOI
高影响因子
CHEMISTRY-A EUROPEAN JOURNAL
·
2018
·Vol. 24
·期 41
·10452-10459
·
IF 5.16
Aoli Wu,Panpan Sun,Na Sun,Liqiang Zheng
Graphical Flick the switch ! A reversible sol–gel phase transition of a prepared supramolecular hydrogel can be triggered by light and temperature. UV irradiation changes the mode of inclusion in the complex formed between β-CD and the azobenzene, whereas thermal treatment influences the hydrogen bonding between β-CD and bis(trifluoromethanesulfonyl)imide (see figure). A low-molecular-weight supramolecular hydrogel has been fabricated based on host–guest interactions between β-cyclodextrin (β-CD) and an asymmetric gemini zwitterionic liquid (ZIL) containing an azobenzene and bis(trifluoromethanesulfonyl)imide. Reversible sol–gel phase transitions were triggered by light and temperature. The binding stoichiometry, mainly noncovalent interactions in the hydrogel, photo- and thermoresponsive mechanisms, and mode of inclusion in the complex were studied in detail by NMR spectroscopy, UV/Vis spectroscopy, isothermal titration calorimetry, and control experiments. Interestingly, the β-CD in the complex can be photo-manipulated to shuttle along the guest molecule, accompanied by a change in the circular dichroism signals. Reversible switching of the conductivity accompanies the sol–gel phase transition, which demonstrates the stability of the supramolecular hydrogel and its potential application in multi-stimuli-responsive electric sensor materials.
研究领域:
材料科学
·
化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ACS Applied Materials & Interfaces
·
2019
·
IF 8.456
Jun-Bo Hou,Xiao-Qin Zhang,Di Wu,Jun-Feng Feng,Duo Ke,Bang-Jing Li,Sheng Zhang
Inspired by animal muscles, we developed a kind of tough elastomers combining high strength and high stretchability with autonomous self-healing capability. A key structural feature is the construction of a double network (DN) connected by the hydrogen bond and host–guest interactions. The first network is the classic elastomer polyacrylate matrix cross-linked by strong hydrogen bonding. The second network is formed through the host–guest interactions between polycyclodextrin and the adamantane (Ad) groups on the side of the polyacrylate chain. Supramolecular interactions between two networks make them miscible and interpenetrate in the molecular level and then can share the load as the sample was stretched. The host–guest interactions act not only as sacrificial bonds for energy dissipation but also as self-healing driving forces. The tensile strength of the DN elastomer reaches about 6.7 MPa and the strain is as high as about 950%. The DN elastomer can be easy to repair by touching the damaged surface together at ambient conditions when broken or cut. The recovered tensile strength can reach over 4.5 MPa, which is better than the most pristine strength of existing spontaneous self-healing elastomers.
研究领域:
材料科学
·
生物仿生学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）