WATER RESEARCH
·
2021
·
IF 11.236
Lixiao Wang,Yajie Zheng,Yiran Zhou,Junhe Lu,Jean-Marc Chovelon,Yuefei Ji
Ketoprofen (KTF) is a nonsteroidal anti-inflammatory drug frequently detected in natural and engineering waters. Because KTF is particularly photolabile (half-life ∼4 min), knowledge of the fate and ecological risks of KTF photoproducts in the aquatic environment is especially essential. Herein, we systematically investigated the photophysics, photochemistry , and photosensitization of KTF photoproducts in aqueous solution under 365 nm irradiation (UV 365 ). Results show that KTF photolyzed rapidly and formed 3-ethyl- α -hydroxylbenzophenone (EtOH-BP), 3-ethyl- α -hydroperoxylbenzophenone (EtOOH-BP), 3-acetylbenzophenone (AcBP), and 3-ethylbenzophenone (EtBP), as identified by liquid chromatography-tandem mass spectrometry (LC-MS/MS) and high-resolution mass spectrometry (HRMS). The presence of O 2 significantly affected the evolution of photoproducts during KTF photolysis. The photophysical properties of EtBP and AcBP were characterized by spectroscopic approaches. In particular, transient absorption spectra obtained by nanosecond laser flash photolysis (LFP) indicated that EtBP and AcBP were excited to triplet states with lifetimes of 28 and 2.4 µs, respectively. EtBP underwent further photodegradation , giving rise to EtOH-BP, EtOOH-BP, and AcBP upon UV 365 irradiation. The reaction is proposed to proceed through an excimer precursor ( 3 [EtBP···EtBP]*) followed by intramolecular H-abstraction. In contrast, AcBP was relatively photostable, particularly under aerated condition. Both EtBP and AcBP have strong photosensitizing activity, as evidenced by the triplet probe 4-( N,N -dimethylamino)benzonitrile (DMABN). ECOSAR program suggested that the photoproducts are more ecotoxic and bioaccumulative than the parent KTF. Results of this study underscore the need to scrutinize the formation and fate of KTF photoproducts in sunlit surface waters.
研究领域:
环境科学
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光化学
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毒理学
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分析化学
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产品关联
DOI
PubMed
高影响因子
MOLECULES
·
2023
·Vol. 29
·期 1
·229
·
IF 4.6
Yunxia Wang,Ye Liu,Bo Liu,Yihua Yuan,Lixia Wei,Mingxiu Wang,Zhe Chen
Faced with rising threats of terrorism, environmental and health risks, achieving sensitive and selective detection of peroxide-based explosives (PEs) has become a global focus. In this study, a turn-on fluorescent probe (BOD) based on benzil (H2O2-recognition element) and 4,4-difluoro-4-bora-3a,4a-diaza-s-indacene (BODIPY) derivative (fluorophore) was developed to sensitively and specifically detect hydrogen peroxide (H2O2). The synthesized BOD had a very weak fluorescence due to intramolecular donor-excited photo-induced electron transfer (d-PET) effect; however, it could emit a strong fluorescence since H2O2selectively oxidized the benzil moiety and released free BODIPY fluorophore (BOD-COOH). As a result, the proposed BOD detected H2O2in linear detection ranged from 25 to 125 µM with a detection limit of 4.41 µM. Meanwhile, the proposed BOD showed good selectivity toward H2O2, which is not affected by other common reactive oxygen species (ROS) and ions from explosive residues. In addition, a blue shift from 508 to 498 nm was observed in the absorption spectra upon addition of H2O2. More importantly, the BOD was successfully applied for rapid detection of H2O2vapor with good sensitivity (down to 7 ppb), which holds great potential for practical use in public safety, forensic analysis and environmental monitoring.Keywords:turn-on fluorescence;benzil;BODIPY;hydrogen peroxide (H2O2);vapor detection
研究领域:
分析化学
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环境科学
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公共安全
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产品关联
DOI
PubMed
高影响因子
APPLIED PHYSICS A-MATERIALS SCIENCE & PROCESSING
·
2017
·Vol. 123
·期 6
·1-4
·
IF 1.455
Wen Xiaoyu,Pan Xiaona,Wu Libin,Li Ruinan,Wang Dan,Zhang Jinqiu,Yang Peixia
Lamellar tin deposits were prepared by galvanostatical electroplating from the aqueous acidic-sulfate bath, with gelatin and benzalacetone dissolved in ethanol (A BA+EtOH ) as additive, and their morphologies were investigated by scanning electron microscopy. Cathodic polarization curves revealed that the absorbability of A BA+EtOH on the cathode surface was higher than that of gelatin. X-ray diffraction analysis indicated preferred orientations of tin growth led to the formation of lamellar structure and distortion of tin lattice. The growth mechanism of lamellar tin was also discussed.
研究领域:
材料科学
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电化学
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产品关联
DOI
高影响因子
JOURNAL OF SOL-GEL SCIENCE AND TECHNOLOGY
·
2013
·Vol. 69
·期 2
·370-377
·
IF 1.66
Xiang Di,Qu Fengyu,Chen Xiang,Yu Zhou,Cui Liru,Zhang Xu,Jiang Jingjie,Lin Huiming
Monodispersed porous ZnO nanospheres with diameters about 400–600 nm were successfully fabricated by a facile and effective cationic surfactant assisted selective etching strategy. The as-synthesized ZnO materials were characterized by X-ray diffraction, scanning electron microscope, transmission electron microscope and N 2 adsorption–desorption. These samples were used as the gas sensor, showing the high, stable and fast response to acetone, revealing the potential application as gas sensor to detect acetone. In addition, the photocatalytic degradation property of the porous ZnO nanospheres for methyl orange (MO) under UV irradiation was investigated. The degradation efficiency of MO reaches 96 % of the porous ZnO samples after 50 min of UV-light irradiation.
研究领域:
材料科学
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纳米技术
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分析化学
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环境科学
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传感器技术
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DOI
高影响因子
JOURNAL OF ALLOYS AND COMPOUNDS
·
2022
·
IF 6.371
Jingxuan Wu,Song Zou,Bo Wang,Changhao Feng,Tatsuo Yoshinobu
Acetone not only harms the human body but is also considered a diabetes biomarker. A series of acetone-sensitive W-doped ZnFe 2 O 4 composite nanofibers were successfully prepared in this study using a simple single-spinneret electrospinning method and a 600 °C calcination treatment. The crystalline phase, morphology, and elemental composition of ZnFe 2 O 4 nanofibers with varying levels of W doping were systematically characterized and analyzed. The gas-sensitive sensing properties of the nanofibers were also thoroughly investigated. The results demonstrate that W is successfully doped into the ZnFe 2 O 4 lattice, leading to a significant reduction in the crystallite size that composes the nanofibers and the formation of Fe 2 O 3 olive-shaped nanoparticle embellishments on the surface of nanofibers. Meanwhile, the generation of heterojunctions and reduction of crystallite size significantly enhance the sensitivity and selectivity of ZnFe 2 O 4 to acetone vapor. The sensors based on 6 mol% W-doped ZnFe 2 O 4 composite nanofibers, in particular, exhibit a response of up to 1.95 for 0.125 ppm acetone vapor at 200 °C. Finally, a comprehensive examination of the acetone sensing mechanism of W-doped ZnFe 2 O 4 is performed, as well as the potential causes for morphological changes and heterojunctions to improve the gas-sensitive performance of ZnFe 2 O 4 .
研究领域:
材料科学
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传感器技术
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医学检测
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产品关联
DOI
高影响因子
JOURNAL OF ORGANIC CHEMISTRY
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2022
·
IF 4.198
Shihai Lv,Ya-Nan Tian,Yanyan Yang,Chaoying Wen,Shiqing Li
An efficient one-pot synthesis of 1,1′-biisoquinolines by a three-component reaction of commercially available raw materials (benzils, NH4OAc, and alkynes) is disclosed. This complicated reaction involves in situ diimine formation via benzil-NH4OAc condensation, Rh(III)-catalyzed 2-fold imine-directed C–H activation, and annulation with alkynes. Both symmetric and unsymmetric 1,1′-biisoquinolines could be assembled in moderate to high yields. The reaction mechanism is supported through ESI-MS, in which Cp*ClRh+, Cp*(OAc)Rh+, Cp*(OPiv)Rh+, and two rhodacycle intermediates are successfully detected to explain the evolution of rhodium species.
研究领域:
有机化学
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合成化学
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DOI
高影响因子
POLYHEDRON
·
2022
·
IF 2.975
Xian-Hao Feng,Zhi-Chao Yu,Wei Zhang,Carl Redshaw,Timothy J. Prior,Tie-Hong Meng,Chun-Rong Li,Zhu Tao,Xin Xiao
In the work, we have studied the interaction of cucurbit[7]uril (Q[7]) with 1-[4-(dimethylamino)phenyl]-ethanone (DAPE) using a variety of techiniques including 1 H NMR spectroscopy, UV–vis adsorption and fluorescence spectroscopies, Isothermal titration calorimetry and single crystal X-ray diffraction. Results revealed the formation of a 1:1 complex, whilst the molecular structure of the species [(Q[7]@DAPE)Ca(H 2 O) 3 ] 2 (CdCl 4 ) 2 ·31(H 2 O) is reported.
研究领域:
化学
·
分子生物学
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DOI
高影响因子
JOURNAL OF CHEMICAL AND ENGINEERING DATA
·
2021
·
IF 2.694
Kui Wu,Xiaofang Li,Lingfeng Xu,Runlin Han,Xiaobing Liu,Yajun Li,Dingwa Zhang,Yan Sui
For the design, optimization, and control of the solution crystallization process of diacetone acrylamide (DAAM), solid–liquid equilibrium data in various solvents are critical. In this work, the solubility of DAAM in 15 pure solvents, such as methanol, ethanol, n-propanol, isopropanol, n-butanol, 1-hexanol, isobutanol, n-pentanol, isopentanol, 2-butanone, acetone, ethyl acetate, 2-pentanone, acetonitrile, methyl acetate, and ethyl formate, is analyzed by a gravimetric method under ambient pressure and temperatures ranging from 272.05 to 323.65 K. The solubility values in all of the solvents are positively correlated with temperature. The solubility of DAAM can be satisfactorily correlated by the Apelblat equation, λh equation, nonrandom two-liquid (NRTL) model, and Wilson model, and the calculated solubility agrees well with the measured results. The obtained maximum relative average deviation (RAD) and root-mean-square deviation (RMSD) are 2.44 × 10–2 (n-propanol, NRTL model) and 2.40 × 10–2 (methanol, λh equation), respectively. The most suitable model is the Apelblat equation.
研究领域:
化学工程
·
热力学
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产品关联
DOI
高影响因子
Science China-Chemistry
·
2021
·Vol. 65
·期 1
·153-161
·
IF 9.445
Shen Saiji,Wu Chu,Shang Yinghui,Shen Hongdou,Liao Yue,Guo Yuting,Hu Min,Wang Xia,Li Gang,Wang Qigang
There are several natural materials which have evolved functional gradients, ingeniously attaining maximal efficacy from limited components. Herein, we utilized the spatiotemporal distribution of initiator acetylacetone to regulate the multienzyme polymerization and fabricate a chitosan-polymer hydrogel. The temporal priority order of acetylacetone was higher than phenol-modified chitosan by density functional theory calculation. The acetylacetone within the gelatin could gradually diffuse spatially into the chitosan hydrogel to fabricate the composite hydrogel with gradient network structure. The gradient hydrogel possessed a transferring topography from the two-dimensional pattern. A continuously decreased modulus along with acetylacetone diffusion was confirmed by atomic force microscope-based force mapping experiment. The water-retaining ability of various regions was confirmed by low-field nuclear magnetic resonance (NMR) and thermogravimetric analysis (TG) analysis, which led to the spontaneous actuation of gradient hydrogel with maximum 1821°/h curling speed and 227° curling angle. Consequently, the promising gradient hydrogels could be applied as intelligent actuators and flexible robots.
研究领域:
材料科学
·
生物化学
·
智能材料
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产品关联
DOI
高影响因子
ACS Omega
·
2024
·
IF 3.7
Chengchun Chen,Duoyun Li,Yongpeng Shang,Zhiwei Lin,Zewen Wen,Peiyu Li,Zhijian Yu,Zhong Chen,Xiaoju Liu
Enterococcus faecalis infections pose a significant clinical challenge due to their multidrug resistance and propensity for biofilm formation. Exploring alternative treatment options, such as repurposing existing drugs, is crucial in addressing this issue. This study investigates the antibacterial activity of candesartan cilexetil against E. faecalis and elucidates its mechanism of action. Candesartan cilexetil exhibited notable antibacterial activity against both E. faecalis and Enterococcus faecium, with minimum inhibitory concentration (MIC) of ≤25 μM. Time-kill curves demonstrated concentration-dependent bactericidal effects. Candesartan cilexetil could significantly inhibited biofilm formation at the concentration of 1/4× MIC and induced alterations in biofilm structure. Permeability assays revealed compromised bacterial membranes, accompanied by the dissipation of membrane potential in E. faecalis cells after treatment with candesartan cilexetil. Checkerboard analysis showed that bacterial membrane phospholipids phosphatidylglycerol and cardiolipin could neutralize the antibacterial activity of candesartan cilexetil in a dose-dependent manner. Biolayer interferometry (BLI) assay indicated specific interactions between candesartan cilexetil and phosphatidylglycerol or cardiolipin. This study demonstrates the promising antibacterial and antibiofilm activities of candesartan cilexetil against multidrug-resistant E. faecalis. The mechanism of action involves disruption of bacterial membranes, possibly by interacting with membrane phospholipids. These findings underscore the potential utility of candesartan cilexetil as an effective therapeutic agent for combating E. faecalis infections, offering a valuable strategy in the battle against antibiotic-resistant pathogens.
研究领域:
微生物学
·
药理学
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产品关联
DOI
PubMed
高影响因子
JOURNAL OF MEMBRANE SCIENCE
·
2024
·
IF 8.4
Yinlu Ye,Nianxiang Qiu,Zhiheng Qiu,Jianqiang Wang,Yingyao He,Fu Liu
The regulation of monomer diffusion in interfacial polymerization played a vital role in manipulating structure and enhancing separation performance of nanofiltration (NF) membrane. The co-solvent strategy has been recognized to be valid and applicable for improving membrane performance. However, the underlying mechanism for its effect on the diffusion progress of amine monomers was still unclear and contradictory. In this study, we found that the added co-solvent (acetone) induced piperazine diffusion flood through interfacial co-solvent extraction effect due to the interfacial enrichment of acetone and innovatively proposed a concept of “acetone extraction effect”. The mechanism and molecular dynamics simulation (MD) were used to systematically explain the effect of diffusion on the morphology and properties of the membranes. The prepared NF membranes exhibited improved separation performance for Calcium (CaCl 2 , 71.5 ± 0.6 %) and Magnesium (MgCl 2 , 83.1 ± 0.8 %) ions, which were better than many of the recorded membranes. This study provided a new idea for the co-solvent effect in interfacial polymerization and promising guidance for the preparation of superior NF membranes.
研究领域:
材料科学
·
环境工程
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
·
2014
·
IF 3.107
Xuefei Cao,Xinwen Peng,Shaoni Sun,Linxin Zhong,Runcang Sun
Hydrothermal conversion is an important thermochemical process to upgrade low-cost lignocellulose into valuable chemicals or fuels. Studies on hydrothermal products compositions and their distributions are of great significance in lignocellulose upgradation. In this work, the major products of bamboo hydrothermally treated at 180–240 °C for 3–60 min and their distributions were comparatively studied. According to the hydrothermal conditions, the hydrothermal products were composed of 37.11–89.98% of solid residues, 4.51–20.41% of water-soluble fractions (WS), and 4.23–16.17% of acetone-soluble fractions (AS). The products in WS fractions mainly consisted of furfural (FF), 5-hydroxymethylfurfural (HMF), and phenolic compounds, while the products in AS fractions were mainly 4-hydroxy-4-methyl-2-pentanone and complex aromatic compounds with multibenzene rings. Additionally, the highest yields of FF (33.4%) and HMF (15.6%) were observed at 200 °C for 60 min and 240 °C for 60 min, respectively.
研究领域:
生物质能
·
化学工程
·
林产化工
✓ 已验证
DOI
PubMed
高影响因子
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