FOOD CHEMISTRY
·
2018
·
IF 4.946
Hossein Mohammadzadeh-Aghdash,Yousef Sohrabi,Ali Mohammadi,Dariush Shanehbandi,Parvin Dehghan,Jafar Ezzati Nazhad Dolatabadi
Cytotoxicity and genotoxicity of sodium acetate (SA), sodium diacetate (SDA), and potassium sorbate (PS) was tested on Human Umbilical Vein Endothelial Cells (HUVEC). Cytotoxicity was investigated by MTT assay and flow cytometry analysis, while genotoxicity was evaluated using DNA fragmentation and DAPI staining assays. The growth of treated HUVECs with various concentrations of SA , SDA and PS decreased in a dose-and time-dependent manner. The IC50 of 487.71, 485.82 and 659.96 µM after 24 h and IC50 of 232.05, 190.19 and 123.95 µM after 48 h of treatment were attained for SA, SDA and PS, respectively. Flow cytometry analysis showed that early and late apoptosis percentage in treated cells was not considerable. Also neither considerable DNA fragmentation nor DNA smear was observed using DAPI staining and DNA ladder assays. Overall, it can be concluded that the aforementioned food additives can be used as safe additives at low concentration in food industry.
研究领域:
毒理学
·
食品科学
·
细胞生物学
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DOI
PubMed
高影响因子
Animals
·
2025
·Vol. 15
·期 6
·844
·
IF 2.7
Shengchen Zheng,Jianwei Lin,Yong Chen,Changjiang Zang,Fan Yang,Jiahao Li,Xiaobin Li
Simple SummaryThis study examines the impact of sodium acetate and sodium butyrate supplementation on the compositional profile, blood biochemical parameters, and volatile flavor compounds of lactating mares’ milk. By employing comprehensive analytical techniques, including Gas Chromatography–Ion Mobility Spectrometry (GC-IMS), this study elucidates the effects of these additives on both the chemical composition and sensory attributes of the milk. The findings offer critical insights into optimizing its flavor profile, enhancing overall quality, market appeal, and nutritional value.This study aims to explore the impact of adding sodium acetate and sodium butyrate on the composition, blood biochemical parameters, and volatile flavor compounds of lactating mares’ milk. By assessing the influence of these additives on milk flavor enhancement, the findings provide scientific evidence for optimizing flavor characteristics and offer new strategies for improving the sensory attributes of mare milk products. Eighteen lactating Yili mares were randomly assigned to three groups: a control group, a sodium acetate group (85 mg/kg·BM−1), and a sodium butyrate group (85 mg/kg·BM−1). The experiment lasted 90 days, with milk yield recorded on days 0, 30, 60, and 90. Milk samples were collected on day 60 (peak lactation) for compositional analysis, and GC-IMS was employed to identify and quantify volatile compounds. Additionally, blood samples were drawn from the jugular vein before morning feeding on day 60 using heparinized tubes to assess key biochemical markers, including glucose, triglycerides, total cholesterol, and urea. The results revealed the following findings: (1) Milk yield and composition: The addition of sodium acetate and sodium butyrate had no significant effect on milk yield. However, both treatment groups exhibited significantly or extremely significantly higher milk fat content compared to the control group, whereas milk protein and lactose levels remained largely unchanged. (2) Blood biochemical indicators: The sodium butyrate group showed an extremely significant increase in urea levels compared to the sodium acetate and control groups. Glucose levels in the sodium acetate group were also significantly higher than in the control group. Moreover, triglyceride levels were markedly elevated in the sodium butyrate group compared to the sodium acetate group, while total bilirubin concentrations were significantly higher in the sodium acetate group than in the control group. (3) Volatile compounds: The addition of these additives led to a significant increase in the diversity and concentration of volatile compounds in mare milk. Notably, esters, aldehydes, and ketones showed substantial enrichment in both treatment groups. The relative abundance of esters such as butyl acetate, L-lactic acid ethyl ester, 1-pentene-3-ol, pentanol, and 3-pentanone increased, alongside a significant rise in aldehydes and ketones, including 2-heptenal and 3-pentanone. In conclusion, sodium acetate and sodium butyrate enhance milk flavor by modulating milk composition and metabolic parameters, providing a scientific foundation for improving the quality of mare milk products.
研究领域:
食品科学
·
动物营养学
·
代谢组学
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产品关联
DOI
PubMed
高影响因子
JOURNAL OF ALLOYS AND COMPOUNDS
·
2017
·
IF 3.133
Jiangdong Dai,Sujun Tian,Yinhua Jiang,Zhongshuai Chang,Atian Xie,Ruilong Zhang,Yongsheng Yan
It is still a big challenge to obtain porous carbons for antibiotics removal by simple methods. Here, we reported a facile, cost-effective and one-pot approach for preparation of porous carbon sheets via in-situ template and self-activation using potassium acetate as single precursor. The optimal porous carbon was prepared at reaction temperature of 900 °C to obtain the highest BET surface area of 2358.57 m 2 g −1 with equilibrium adsorption capacity of 588.24 mg g −1 for chloramphenicol (CAP) at 298 K . The adsorption ability of this highly porous carbon was far higher than most adsorbents mentioned in previous literature. Meanwhile, adsorption equilibrium could achieve rapidly within 250 min. The Langmuir isotherm model and pseudo-second-order kinetic model were well fitted to adsorption experimental data. Significantly, the adsorbent exhibited excellent stability and regeneration performance after four times cycles. The high adsorption capacity, fast kinetic, chemical stability and regeneration ability of this porous carbon make it a candidate for antibiotics removal in wastewater treatment.
研究领域:
环境科学
·
材料科学
✓ 已验证
产品关联
DOI
高影响因子
APPLIED CATALYSIS B-ENVIRONMENTAL
·
2024
·
IF 20.2
Siyuan Luo,Haiyuan Zou,Renji Zheng,Shimao Deng,Xuezhen Feng,Wenfei Wei,Ranhao Wang,Ze Li,Wei Xu,Lele Duan,Hong Chen
Selective electrochemical reduction of CO 2 /CO to high-valuable C 2+ products is of great importance to alleviate the global warming and energy crisis problems, while the selective production of C 2 is severely limited by the C C coupling pathway on the catalyst interface. Herein, by employing a Cu + /Cu 2+ charge-ordered metal-organic framework (MOF) material (denoted to be Cu4BHT) as a CO electroreduction catalyst, a high acetate selectivity of 50.3% at 0.7 V versus reversible hydrogen electrode (RHE) has been achieved. An in-depth mechanism study reveals that the charge-ordered Cu + /Cu 2+ pair on Cu4BHT interface favors the C O bond activation, C C coupling, and proton-coupled electron transfer dynamics, which results in the selective formation of C 2+ products. This work illustrates the critical role of employing charge-ordered Cu + /Cu 2+ catalytic site pair for C C coupling, which paves the way for designing highly selective catalysts to promote the formation of the C 2 products.
研究领域:
材料科学
·
电化学
·
能源科学
✓ 已验证
产品关联
DOI
高影响因子
Nutrients
·
2023
·Vol. 15
·期 17
·3736
·
IF 5.9
Changbao Sun,Ang Li,Huan Wang,Jiage Ma,Juncai Hou
Acetate is associated with adipocyte differentiation and lipid deposition. To further develop this scientific point, obese mice on a high-fat diet were given an intragastric administration of acetate for 8 weeks and mouse adipose mesenchymal stem cells (mAMSCs) were treated with acetate for 24 h. The results showed that the body weight, food intake, Lee’s index, adipose tissue coefficient, liver index, blood lipid levels, insulin resistance, pro-inflammatory factors levels and fatty lesions in liver and adipose tissue in obese mice treated with acetate increased markedly, while anti-inflammatory factors levels and liver function decreased significantly (p< 0.05). The mRNA expression levels of PPAR-γ, C/EBP-α, SREBP, AFABP, FAS, ACC-1, SCD-1, LPL, LEPR, GPR41 and GPR43 genes in adipose tissue and mAMSCs were significantly increased, while the mRNA expression levels of HSL, CPT-1, CPT-2, AMPK, AdipoR1 and AdipoR2 genes were significantly reduced (p< 0.05). Except for AMPK-α signaling pathway proteins, the phosphorylation levels of p38 MAPK, ERK1/2, JNK and mTOR were significantly increased (p< 0.05) and these changes were dose-dependent. The findings indicated that acetate played a positive role in regulating adipocyte differentiation and lipid deposition by activating MAPKs and mTOR signaling pathways (the expression up-regulation of genes such as PPAR-γ, C/EBP-α and SREBP-1, etc.) and inhibiting the AMPK signaling pathway (the expression down-regulation of genes such as HSL, CPT-1 and AMPK-α, etc.).Keywords:obesity;lipid metabolism;acetate;adipocyte differentiation;lipid deposition
研究领域:
营养学
·
分子生物学
·
内分泌学
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产品关联
DOI
PubMed
高影响因子
Nature Synthesis
·
2024
·Vol. 3
·期 7
·891-902
·
IF 0
Cai Yanming,Yang Ruixin,Fu Jiaju,Li Zhe,Xie Liangyiqun,Li Kai,Chang Yu-Chung,Ding Shichao,Lyu Zhaoyuan,Zhang Jian-Rong,Zhu Jun-Jie,Lin Yuehe,Zhu Wenlei
The selective one-step CO 2 electroreduction reaction (CO 2 RR) to acetate and propanol has garnered intense interest. Here we report the design of self-pressurizing nanoscale capsule catalysts for the CO 2 RR. A high-pressure CO intermediate environment is created around copper catalysts by a permselective enclosure. Microkinetic modelling, 13 CO 2 / 12 CO co-feed experiments and in situ Raman spectroscopy confirm that a unique CO–CO 2 coupling path is involved, which is only initiated at high CO intermediate pressure. This pathway benefits acetate production due to the kinetic and energetic advantages of COCO 2 *. The acetate Faradaic efficiency is 38.5 ± 2.2% (8 times higher than that achieved without enclosure) and the acetate partial current density is 328 ± 19 mA cm −2 , which surpasses the performance of previous CO 2 RR catalysts. In situ investigation indicates that the CO pressure inside the nanoscale capsule catalysts can reach 8 ± 3 bar. Furthermore, self-pressurizing nanoscale capsule catalysts with a CuI-derived core can reduce CO 2 to propanol with a Faradaic efficiency of 25.7 ± 1.2% and a conversion rate of 155 ± 3 mA cm −2 .
研究领域:
材料科学
·
催化化学
·
环境科学
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产品关联
DOI
Small
·
2021
·Vol. 17
·期 46
·2102186
·
IF 13.281
Pengyun Liu,Yonghui Chen,Huimin Xiang,Xiaoqing Yang,Wei Wang,Ran Ran,Wei Zhou,Zongping Shao
Both the film quality and the electronic properties of halide perovskites have significant influences on the photovoltaic performance of perovskite solar cells (PSCs) because both of them are closely related to the charge carrier transportation, separation, and recombination processes in PSCs. In this work, an additive engineering strategy using antimony acetate (Sb(Ac) 3 ) is employed to enhance the photovoltaic performance of methylammonium lead iodide (MAPbI 3 )-based PSCs by improving the film quality and optimizing the photoelectronic properties of halide perovskites. It is found that Ac − and Sb 3+ of Sb(Ac) 3 play different roles and their synergistic effect contributed to the eventual excellent photovoltaic performance of MAPbI 3 -based PSCs with a power conversion efficiency of above 21%. The Ac − anions act as a crystal growth controller and are more involved in the improvement of perovskite film morphology. By comparison, Sb 3+ cations are more involved in the optimization of the electronic structure of perovskites to tailor the energy levels of the perovskite film. Furthermore, with the assistance of Sb(Ac) 3 , MAPbI 3 -based PSCs deliver much improved moisture, air, and thermal stability. This work can provide scientific insights on the additive engineering for improving the efficiency and long-term stability of MAPbI 3 -based PSCs, facilitating the further development of perovskite-based optoelectronics.
研究领域:
材料科学
·
能源科学
✓ 已验证
DOI
高影响因子
JOURNAL OF ALLOYS AND COMPOUNDS
·
2025
·
IF 6.3
Mengchun Zhu,Shengyi Yang,Guanzhen Zou,Haiyuan Xin,Zhenhua Ge,Ying Wang,Bingsuo Zou,Yurong Jiang
As a promising material, lead selenide (PbSe) colloidal quantum dots (CQDs) are widely studied for its applications in the next generation photodetectors due to their solution-processability and low cost. However, the (100) surfaces PbSe QDs are usually passivated incompletely by the traditional liquid-phase ligand exchange with the halogen ligands when the diameter of PbSe QDs is larger than 5.0 nm. As compared to the traditional strategies of the halogen ligands, in this work methylammonium acetate (MAAc) was added as an additive into the PbI 2 ligand solution to form the perovskite intermediate (i.e. MAPbI 3-x Ac x ) as the ligand attached onto the (100) face of PbSe, in this way, to enhance the surface passivation and the dispersion of PbSe CQDs. Therefore, the as-synthesized infrared photodetector ITO/ZnO/PbSe-MAPbI 3-x Ac x /Ag showed decreased dark current by more than five-fold, and thus its device performance is enhanced greatly. As a result, a high photoresponsivity of 0.32 mA/W with a specific detectivity of 1.16 × 10 11 Jones was obtained from the photodetector ITO/ZnO/PbSe-MAPbI 3-x Ac x /Ag under 47.8 µW/cm 2 1550 nm illumination. Thus, it provides a supplemental solution to completely surface-passivate CQDs in large size for next generation optoelectronics.
研究领域:
材料科学
·
光电技术
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产品关联
DOI
高影响因子
ACS Applied Materials & Interfaces
·
2024
·
IF 8.3
Zhekun Shi,Zhuo Wang,Kangjian Xiao,Bo Zhu,Yan Wang,Xiaolong Zhang,Zhen Lin,Di Tan,Longjian Xue
Reversible adhesives are widely needed in our daily lives and industrial applications. However, robust and switchable adhesion on rough surfaces with on-demand attachment and detachment remains highly challenging. Here, we report a snail-mucus-inspired touch-responsive hydrogel (TRH), whose universal and robust adhesion is triggered by simple contact with the attaching surface. TRH is composed of a polymeric hydrogel and saturated sodium acetate (NaAc) and is prepared by one-pot synthesis. At room temperature, TRH remains in an amorphous and soft state, which allows it to conformally adapt to rough surfaces. The contact with the target surface triggers the crystallization of NaAc, which increases the modulus of TRH by an order of magnitude and interlocks with the target surfaces, achieving an adhesion of up to 204.84 ± 53.98 kPa. Upon heating, TRH returns to a soft state, facilitating easy detachment with adhesion of 5.12 ± 1.34 kPa. Meanwhile, the detached TRH is ready for the next adhesion without the need to be maintained at high temperature. TRH finds applications as a smart material for light-triggered adhesion switching, information encryption, and temperature sensors.
研究领域:
材料科学
·
生物仿生学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Small
·
2025
·
IF 12.1
Lubo Li,Zeqi Liu,Geliang Dai,Yong Xia,Lijian Xu,Aokui Sun,Jingjing Du
Rechargeable aqueous zinc-ion batteries (AZIBs) draw much attention for low cost and high safety. However, hydrogen evolution reaction (HER) and uneven Zn 2+ deposition shorten lifespan, hampering commercial use. In this study, sodium dehydroacetate (SD) containing carbonyl and keto-carbonyl is introduced as multifunctional electrolyte additives, which effectively modifies the solvent shell structure, achieving a Zn 2+ transference number of up to 0.72. Acting as a hydrogen bond acceptor, SD disrupts the water network structure, thereby increasing the HER overpotential by 22 mV and the corrosion potential by 9 mV. The polar functional groups in SD can reversibly capture H⁺ ions and dynamically neutralize OH⁻ ions, maintaining interfacial pH balance on the zinc anode and suppressing HER. Notably, SD not only alters the electrolyte's kinetic but also induces uniform Zn 2+ deposition along the (002) plane, inhibiting dendrite growth and minimizing side reactions. This phenomenon is demonstrated in both symmetric and full-cell configurations. The Zn//Zn symmetric cell achieves an ultra-long cycling lifespan of 2800 hours at 5 mA cm⁻ 2 , and the Zn//VO 2 full battery maintains a capacity retention rate of 73.09% after 2000 cycles with a high average coulombic efficiency of 99.98%, underscoring the effectiveness of this electrolyte additive in enhancing battery performance.
研究领域:
电化学
·
材料科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Materials Science & Engineering C-Materials for Biological Applications
·
2017
·
IF 4.164
Yuwei Zhou,Ke Hu,Zhaobin Guo,Kun Fang,Xing Wang,Fang Yang,Ning Gu
In this study, composite antibacterial microcapsules combining of two antibacterial agents: chlorhexidine acetate and silver nanoparticle were prepared. The chlorhexidine acetate was encapsulated inside of the microcapsules and nano-sized silver particles were modified on the surface of microcapsules by electrostatic adsorption methods. Results show that this method decreases the silver usage dramatically, and promises a sustained antibacterial effect > 30 days. These microcapsules can also be modified on the surface of polymer films easily, which demonstrated the potential in functionalizing the implanted materials with antibacterial property.
研究领域:
材料科学
·
微生物学
·
生物医学工程
✓ 已验证
DOI
高影响因子
ChemistrySelect
·
2024
·Vol. 9
·期 3
·e202303342
·
IF 1.9
Nianming Jiao,Junjie Cui,Long Liu,Yuan Yao,Yangfeng Xia,Yanqiang Zhang
Graphical Pyridinium trifluoroacetate-based ILs effectively catalyzed the cyclization of 2-propyl ketazine to pyrazolines, achieving conversion and selectivity rates of 98 % and 99 %, respectively. Thermodynamic data were obtained through DFT calculations and calorimeter tests, providing valuable insights for the practical application of ketazine intramolecular cyclization to synthesize pyrazolines. In this work, pyridinium trifluoroacetate ionic liquids, as a protonic acid catalyst, were used to catalyze intramolecular cyclization of ketazine to synthesize 2-pyrazoline. The investigation encompassed the impact of temperature, solvent, dosage of ionic liquid catalyst, and the structure-activity relationship in the cyclization reaction of 2-propyl ketazine. The optimal catalytic performance was achieved at 100 °C with 8 mol % of 3,5-dimethylpyridinium trifluoroacetate in a solvent-free environment. Moreover, thermodynamic and kinetic data were determined through density functional theory calculations and calorimetric experiments. These protonic acid ionic liquids address the issue of excessive traditional protonic acid dosage in the intramolecular cyclization of ketazine, while also presenting a viable pathway for the catalytic synthesis of 2-pyrazolines.
研究领域:
有机化学
·
催化化学
·
材料科学
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）