PLoS One
·
2014
·Vol. 9
·期 12
·e114300
·
IF 3.534
Xingchu Gong,Ying Zhang,Jianyang Pan,Haibin Qu
A solvent recycling reflux extraction process for Panax notoginseng was optimized using a design space approach to improve the batch-to-batch consistency of the extract. Saponin yields, total saponin purity, and pigment yield were defined as the process critical quality attributes (CQAs). Ethanol content, extraction time, and the ratio of the recycling ethanol flow rate and initial solvent volume in the extraction tank (RES) were identified as the critical process parameters (CPPs) via quantitative risk assessment. Box-Behnken design experiments were performed. Quadratic models between CPPs and process CQAs were developed, with determination coefficients higher than 0.88. As the ethanol concentration decreases, saponin yields first increase and then decrease. A longer extraction time leads to higher yields of the ginsenosides Rb 1 and Rd. The total saponin purity increases as the ethanol concentration increases. The pigment yield increases as the ethanol concentration decreases or extraction time increases. The design space was calculated using a Monte-Carlo simulation method with an acceptable probability of 0.90. Normal operation ranges to attain process CQA criteria with a probability of more than 0.914 are recommended as follows: ethanol content of 79–82%, extraction time of 6.1–7.1 h, and RES of 0.039–0.040 min −1 . Most of the results of the verification experiments agreed well with the predictions. The verification experiment results showed that the selection of proper operating ethanol content, extraction time, and RES within the design space can ensure that the CQA criteria are met.
研究领域:
植物化学
·
药学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
SENSORS AND ACTUATORS A-PHYSICAL
·
2023
·
IF 4.6
Gangqiang Tang,Yujun Ji,Chun Zhao,Dong Mei,Xin Zhao,Jie Ru,Lijie Li,Yanjie Wang
Ionic polymer metal composite (IPMC) is a kind of smart material that integrates functions of actuating and sensing. In this paper, we demonstrated a new sensing function of IPMC to detect the concentration of ethanol by investigating the effects of ethanol content on the electrical response of IPMC. Benefiting from the ion migration effect in the Nafion matrix , the voltage of IPMC varies with different ethanol concentrations . It was found that the response process of IPMC to ethanol solution can be divided into a rapid response stage caused by concentration difference and a slow response stage caused by uneven mechanical stress. The voltage change caused by the concentration difference was defined as the response voltage, and the sensitivity of the IPMC sensor to ethanol concentration was 4.39 mV. We have demonstrated the good cyclability and stability of IPMC to ethanol by experiments. Furthermore, the IPMC sensor was applied to respiratory monitoring after drinking. It has been proven that the IPMC sensor can monitor the changes in alcohol concentration after drinking, which is of great significance for the prevention of stroke after drinking.
研究领域:
材料科学
·
生物医学工程
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF FOOD BIOCHEMISTRY
·
2020
·Vol. 44
·期 5
·e13171
·
IF 1.662
Guang-jing Chen,Chun-xia Ran,Chang-feng Li,Zheng-wei Xiong,Li-zhi Ma
Three polysaccharide fractions from bamboo shoot ( Chimonobambusa quadrangularis ), CPS70, CPS75, and CPS80, were prepared using a final ethanol concentration of 70%, 75%, and 80% in the precipitation process. In vitro digestibility and the prebiotic activity of CPS70, CPS75, and CPS80 were evaluated and compared. The results indicated that all three of the CPS fractions exhibit a high degree of nondigestibility to human gastric juice (>98.5%) or α-amylase hydrolysis (>94.5%). Compared with the blank control, the three CPS fractions could not only significantly ( p < .05) stimulate the proliferation of B. adolescentis , B. infantis , B. bifidum, and L. acidophilus , but also significantly ( p < .05) enhance the production of lactic, acetic, propionic, and butyric acids when these polysaccharides were added as alternative carbon sources to glucose during the in vitro fermentation of four probiotics. Furthermore, when comparing the three CPS fractions, CPS75 displayed the strongest prebiotic potential, as this polysaccharide had the strongest effect on the proliferation of probiotic bacteria as well as the greatest effect on SCFAs production. These results demonstrated that the concentration of ethanol used during the precipitation process has a significant impact on the prebiotic activity of CPS. Practical applications Ethanol precipitation is the first step when extracting polysaccharides from aqueous extracts as it is simple, rapid, and easy to carry out. This study focuses on how different concentrations of ethanol used in the precipitation process affect the prebiotic potential of bamboo shoot ( Chimonobambusa quadrangularis ) polysaccharides (CPS). The result indicated that the concentration of ethanol used during the precipitation process has a significant impact on the prebiotic activity of CPS. To our knowledge, it is the first to evaluate the effects of the concentration of ethanol during the process of precipitation on prebiotic potential of polysaccharides, which can subsequently be applied to the optimization of ethanol concentration when precipitating natural polysaccharides for the purpose of in vitro fermentation.
研究领域:
食品科学
·
生物化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF FOOD PROCESSING AND PRESERVATION
·
2017
·Vol. 42
·期 2
·e13484
·
IF 0.791
Yi Ma,Chang-Jun Hou,Dan Li,Dan-Qun Huo
This study aimed to evaluate and understand the water–ethanol system effect on the stability of purple-fleshed sweet potato anthocyanins (PSPa). The stability of the PSPa in the model ethanol–water solutions (0–80%, vol/vol, pH 3.5) during storage (60 hr) at room temperature was monitored by UV-vis. The frontier molecular orbital theory was used to interpret the hydration reaction rate of the PSPa in both ethanol–water and aqueous solutions. In all of the model ethanol–water solutions, the degradation of the PSPa followed first-order kinetics during storage, and the degradation rates increased with increased ethanol concentration. Theory calculation results showed that an increase in ethanol concentration decreased the LUMO energy of anthocyanins, and accelerated nucleophilic attack from water, thus, resulting in lower stability. These findings could provide valuable evidence of the solvent effect on the stability of anthocyanins. Practical applications Fruit wines that contain anthocyanins are among the common alcoholic beverages. The stability of the anthocyanins is responsible for wine quality and may also affect the nutritional properties. Thus, investigating the effect of ethanol on the stability of anthocyanins is particularly valuable. The results of this research have important implications for the models developed so far to explain the degradation mechanism of anthocyanins in different media. In this context, examining the effect of different media on the degradation of anthocyanins would be useful to provide improved anthocyanin ability in the food and beverage industry.
研究领域:
食品科学
·
分子生物学
✓ 已验证
产品关联
DOI
高影响因子
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
·
2024
·Vol. 31
·期 23
·34159-34169
·
IF 0
Cao Yu,Zhong Zehui,Zeng Fanqi,Zhou Yang
To ensure the safety of food contact materials, a liquid chromatography method was established to determine the migration of formaldehyde in paper packaging with various food simulants (10%, 25%, 50%, 75%, and 95% ethanol by volume) and to investigate the migration behavior of formaldehyde after various durations and with various materials. The results showed that the method has good linearity with a correlation coefficient of R 2 > 0.9990, a detection limit of 0.0011 ~ 0.0027 mg L −1 , and a spiked recovery of 89.7 ~ 103.2% in the range of formaldehyde determination; the migration of formaldehyde in all six paper contact materials showed a trend of gradual increase with time until equilibrium was reached. At the same time and temperature, the migration of formaldehyde in paper packaging was the highest in low-concentration ethanol. With the same food simulants and materials, the maximum migration of formaldehyde in printed materials was greater than that in nonprinted materials; with different materials and the same food simulant, the thickness value was higher, with the use of water-based ink as a printing material, and the maximum migration value of formaldehyde by offset printing technology was low.
CAS / MDL:
研究领域:
食品安全
·
分析化学
·
材料科学
✓ 已验证
产品关联
DOI
PubMed
LANGMUIR
·
2024
·
IF 3.7
Hang Yuan,Yong Qi,Wenbin Niu,Wei Ma,Shufen Zhang
Photonic crystal-based ethanol concentration indicators with rapid response and brilliant structural color output definitely take a place in colorimetric sensors. Here, based on the H-bond-regulated swelling of acrylate shape memory polymers (SMPs) and the solvent-induced structural color change of the double inverse opal photonic crystals (DIOPCs), new-type photonic crystals (PCs) colorimetric indicators were constructed, exhibiting a span of maximum reflection wavelength (λmax) up to ∼166 nm in response to alcohols with concentrations from 0 to 100 vol %. DIOPC indicators (DIOPCIs) show a rapid response to alcohols (<1.5 s) and output different structural colors (covering from blue to red). The colorimetric sensing mechanism includes the solvent-triggered recovery of the inverse opal skeleton, the cosolvency effect and H-bonds induced swelling/shrinkage of the polymer, the phase separation between polystyrene (PS) microsphere and polymer skeleton, and the light diffraction of DIOPCs. While ensuring a larger λmax span by regulating the H-bond interactions in polymer chains through acrylamide (AAm), AAm-modified DIOPCIs are sensitive to some specific ethanol concentrations. The real-time sensing of ethanol concentration during fermentation verified the practicability of DIOPCIs, thus establishing a visual model between structural color and corresponding fermentation kinetics. We envisage that the DIOPCIs will contribute to the intelligentization of the alcoholic fermentation and distillation industry.
研究领域:
材料科学
·
生物工程
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Communications Materials
·
2024
·Vol. 5
·期 1
·1-11
·
IF 7.5
Yao Chang,Yan Wuwen,Dong Ronglu,Dou Shaobin,Yang Liangbao
The self-assembly of noble metal nanoparticles into periodic structures has been a theme of great interest for surface-enhanced Raman scattering (SERS) and use in functional devices. However, small nanoparticle self-assembly faces numerous challenges in tunability, referring to controlling their structural properties like structure, gaps, and arrangement. These issues highlight the need for further research and development to enhance the tunability and stability of self-assembled small nanoparticles. Here, we report a general centimeter-scale superlattice assembly strategy for noble metal nanoparticles less than 15 nm in size. Not only is this monolayer superlattice assembly generally applicable to different kinds and sizes of noble metal nanoparticles, but also, the crystal plane spacing can also be quickly and conveniently controlled by changing the ethanol concentration. SERS results reveal that optimized superlattice membranes of noble metal nanoparticles possess high detection sensitivity and ordered hot spots. Therefore, our strategy offers prospects for high-performance SERS substrates based on small noble metal nanoparticle superlattices.
研究领域:
材料科学
·
纳米技术
·
光学
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2021
·
IF 8.128
Xia Hongbo,Li Dan,Wu Suli,Feng Shuai,Meng Chao,Dong Bin
Responsive photonic crystals have attracted much attention due to their strong capability to manipulate the propagation of light in the visible region, but it is still a big challenge to invisibility and mechanical stability. Here, the novel Poly(ether sulfone)/Poly(acrylic acid) inverse opal photonic crystals, which have high mechanical stability and can release visible patterns after wetting with water, are discussed. The Poly(ether sulfone)/Poly(acrylic acid) inverse opal photonic crystals are also responsive to the concentration of ethanol, and the structural color response times increase with increasing ethanol concentration. This design uses the selective infiltration, hydrogen bonding and capillary action of solvent to realize the spectral diversity of reflectance. Owing to the high polarity and hydrogen bonding ability of carboxyl groups, water molecules are adsorbed easily by the poly(acrylic acid) gel. Subsequently, the encrypted information is decrypted due to the redshift of the structural color. Because of its lower polarity and hydrogen bonding ability relative to water, ethanol can impede the absorption of solvent by gel. Therefore, the ethanol concentration can be identified based on the structural color response time. Furthermore, reliable information decryption methods make Poly(ether sulfone)/Poly(acrylic acid) inverse opal photonic crystals potentially uesful as trusted encryption devices.
研究领域:
材料科学
·
光学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
RSC Advances
·
2025
·Vol. 15
·期 27
·22154-22160
·
IF 4.6
Yuxuan Liang,Pengfei Du,Yanhong Wei,Xurui Hu,Xiaojie Li,Zhijun Wang,Jie Gong,Mengdi Liu,Panlai Li,Wenge Ding
In this work, a near-infrared (NIR) phosphor Ca0.8Sr0.2O:Eu2+ was prepared via a solid-state method, and its luminescence properties were improved by co-doping with Ce3+ ions. The decay curves of Ca0.8Sr0.2O:Ce3+, Eu2+ confirmed that there was an obvious energy transfer from Ce3+ to Eu2+, which enhanced the quantum efficiency of Ca0.8Sr0.2O:Eu2+. The thermal stability can also be enhanced by introducing Ce, which reduces the probability of non-radiative transitions at elevated temperatures, thereby minimizing electron loss. An NIR light emitting diode (LED) was fabricated by combining a blue LED chip with Ca0.8Sr0.2O:Ce3+, Eu2+, which was applied for the concentration detection of ethanol solutions.
研究领域:
材料科学
·
光学工程
·
分析化学
·
生物医学工程
·
传感器技术
✓ 已验证
产品关联
DOI
PubMed
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2022
·
IF 16.744
Yong Qi,Donghui Kou,Yudong Sun,Tong Hu,Hang Yuan,Changtong Zhou,Chang Li,An-Hui Lu,Suli Wu,Shufen Zhang
Colorimetric sensing of ethanol concentration accelerates the intellectualization of the ethanol industry. The development of alcohol detectors with excellent structural color output and reconfigurable nanostructures will certainly set off reform in colorimeter sensors. Here, a novel portable colorimetric photonic indicator (CPI) that can distinguish alcohol with concentrations from 0 to 100 % was ingeniously fabricated by bridging the copolymer capable of autonomic solvent control with porous structure via shape memory photonic crystals (PCs). CPI shows an ultrafast color response (<1 s) to the perception of ethanol concentration and outputs structural colors from blue to red, with reflection covering ∼477 to ∼628 nm. The coloration and color-change mechanisms of CPI are derived from the hydrogen bonds remodeling among carboxyls, ethylene glycol groups, and solvent molecules, the shape memory effect of the inverse opal skeleton, and the reversible structural transformation induced by the solvent co-solvency effect. We validate the real-time visual concentration-detection capabilities of CPI by measuring the distillate concentration during the alcohol distillation. We envisage that CPIs show potential applications in automated and broad-spectrum molecule-detection devices in biomedical and chemical engineering.
研究领域:
材料科学
·
化学工程
·
生物医学工程
·
传感技术
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF CEREAL SCIENCE
·
2024
·
IF 3.9
Mengting Yan,Chenyang Sun,Jiangtao Yu,Junqing Bai,Huishan Shen,Xiuyun Zhang,Yifan Lu,Zhuangzhuang Sun,Xiangzhen Ge,Wei Liang,Jie Zeng,Haiyan Gao,Guoquan Zhang,Wenhao Li
In this study, sorghum meal underwent 2–10 kGy electron beam irradiation (EBI) to investigate alterations in its elemental composition, relevant physicochemical characteristics, and enzymatic hydrolysis fermentation properties. The results indicated a decrease in amylose content and an increase in reducing sugar content in sorghum meal after EBI, along with severe damage to the internal structure of starch granules, leading to increased solubility in water. Furthermore, irradiation enhanced the shear resistance and gelatinization stability of sorghum meal paste. Most importantly, EBI-induced degradation of sorghum starch molecules enhanced their susceptibility to interact with α-amylase, significantly improving the enzymatic hydrolysis and alcohol fermentation efficiency of sorghum meal. At an irradiation dose of 8 kGy, raw and cooked sorghum meal exhibited a 43.40% and 33.33% increase in ethanol concentration and a 43.44% and 30.29% increase in ethanol yield, respectively. This finding indicated that irradiation is an effective pretreatment method for starch-based ethanol fermentation.
研究领域:
农业工程
·
食品科学
·
生物化学
✓ 已验证
产品关联
DOI
高影响因子
European Journal of Wood and Wood Products
·
2022
·Vol. 81
·期 3
·685-697
·
IF 2.528
Huang Dan,Wang Jing,Li Fanghua,Xie Min,Qu Qingli,Wang Yimin,Sun Wenjuan,Wu Caie,Xu Wenhui,Xiong Ranhua,Ding Yichun,Yang Anquan,Huang Chaobo
In this study, for the first time, optimized phenolic compounds and antioxidant properties were derived from the extraction process of Cortex fraxini (CFR) using response surface methodology. Four factors and three levels of Box-Behnken (BBD) were used to study the extraction time (X 1 ), extraction temperature (X 2 ), ethanol concentration (X 3 ), and solvent-material ratio (X 4 ). The analysis of variance (ANOVA) revealed that temperature and solvent-material ratio had a relatively large effect on the response. The optimal combination of phenolic compounds and antioxidant activity was obtained with the optimal conditions of X 1 = 1.629 h, X 2 = 53.367 ℃, X 3 = 60.971% (v/v), and X 4 = 45.582 mL/g under ultrasonic assisted extraction (UAE). The experimental parameters were consistent with the predicted values. Caffeic acid, erucic acid, ferulic acid and p-hydroxycinnamic acid and other 19 phenolic acids were characterized by high performance liquid chromatography-mass spectrometry (HPLC–MS). The results of this study indicate that optimization of the extraction process is essential for the accurately determined measurement of phenolic components and antioxidants in CFR for its industrial applications.
研究领域:
生药学
·
分析化学
·
药学
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）