Journal of Hazardous Materials Advances
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2022
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IF 0
Yurong Gu,Qi Han,Zijun Dong,Jiaxin Zhu,Chengchun Jiang,Jikun Qi
This study systematically investigated the performance of a sulfite mediated photolytic system on diatrizoate (DTZ) degradation and deiodization under different UV intensity, sulfite dosage, initial solution pH, initial DTZ concentration and co-present constituents. As compared with sole UV photolysis and sole sulfite reduction system, the UV/sulfite system performed a higher efficiency of DTZ degradation and deiodization. At the same time, the scavenging experiments were conducted by respectively adding KNO 3 , KNO 2 , MeOH and TBA, which indicated e aq − was the dominant active species responsible for the enhanced degradation and deiodination of DTZ. Effects of reaction factors showed that the UV/sulfite system was a promising technique for DTZ degradation. A complete removal of DTZ (40 µM) could be obtained under the UV intensity of I 0 (6.67 × 10 −7 einstein/cm 2 ∙s), sulfite dosage of 0.50 mM and pH ranging from 8∼10. In addition, the intermediate products of DTZ degradation were identified and possible degradation mechanism was proposed. Four possible products including TP504, TP488, TP486 and TP236 were obtained in this study. The main degradation pathways might include protonation, deiodination, substitution and heterocyclic formation.
研究领域:
环境科学
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化学工程
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DOI
Journal of Materials Chemistry A
·
2020
·Vol. 8
·期 29
·14634-14643
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IF 11.301
Chuan-Shu He,Rong-Rong Ding,Guan-Nan Zhou,Di He,Peng Fan,Xiao-Hong Guan,Yang Mu
Surface passivation is one of the most challenging aspects in the successful application of zero-valent iron (ZVI) for water decontamination, especially when oxygen is inevitably present. This study found that the coexistence of HA ranging from 0 to 40.0 mg-C/L appreciably improved the pseudo-first-order kinetic rate constant of pollutant diatrizoate (DTA) reduction by ZVI from 0.0454 to 0.1365 h−1 under aerobic conditions. For the first time, it revealed that the coexistence of HA could accelerate the reductive removal of organic contaminants via ZVI surface depassivation rather than the previously proposed electron-shuttle mechanism under aerobic conditions. Interestingly, both DTA removal and Fe0 consumption were found to undergo two stages in the presence of HA, with an initial slight enhancement attributed to the Fe(III)–HA complex formation partially suppressing iron precipitation, followed by a remarkable promotion arising from the HA-associated iron oxide detachment from the Fe0 surface. These findings not only provide a good strategy to enhance ZVI reactivity with minimal extra cost and complexity under aerobic conditions, but also help understand the ZVI behavior in practical applications.
研究领域:
环境科学
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污染治理
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DOI
高影响因子
Catalysts
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2022
·Vol. 12
·期 9
·932
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IF 4.501
Guoyun Sun,Ziyang Huang,Zhiqian Zhang,Yanfeng Liu,Jianghua Li,Guocheng Du,Xueqin Lv,Long Liu
Free enzymes often face economic problems due to their non-recyclability, which limits their applications for industrial manufacturing. Organic biopolymers are frequently used to fabricate hydrogel for enzyme immobilization due to their advantages of non-toxicity, biocompatibility, biodegradability, and flexibility. However, for highly thermostable enzymes, simple cross-linking causes either low immobilizing efficiency or low thermal stability. Herein, we developed a novel enzyme immobilization strategy with two-step cross-linked gelatin hydrogel for thermostable enzymes working at high temperature. The hydrogel was firstly “soft cross-linked” to immobilize most enzyme molecules and then “hard cross-linked” to gain strong thermal stability. We selected the enzyme diacetylchitobiose deacetylase (Dac), which was firstly derived from hyperthermophilic bacteria, to demonstrate the advantages of our method. With the optimized fabrication steps, our hydrogel showed ~87% Dac immobilization efficiency and excellent stability against heating, dehydrating, long-time storing, and massive recycling. Importantly, our hydrogel showed ~85.0% relative enzyme activity at 80 °C and retained ~65.8% activity after 10 rounds of catalysis. This strategy showed high immobilizing efficiency and strong thermal stability and we believe it could improve the industrial potential for those enzymes.Keywords:enzyme immobilization;gelatin hydrogel;two-step cross-linking;diacetylchitobiose deacetylase
研究领域:
生物化学
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材料科学
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DOI
高影响因子
APPLIED SURFACE SCIENCE
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2021
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IF 6.707
Futao Sai,Haitao Zhang,Jianbo Qu,Jianyong Wang,Xiuzhong Zhu,Yang Bai,Peng Ye
Currently, the preparation and application of functional waterborne polyurethane has become a research hotspot in the field of polyurethane. In the present work, Different weight ratios of diacetyl oxime and coumarin diol were used as the reactive filler with isophorone diisocyanate (IPDI) and Poly propylene glycol (PPG) to prepare superior amine-response, self-healing and recyclable waterborne polyurethane films (WPU-x). Dynamic mechanical analysis was carried out to identify the self-healing properties of WPU-x. It was revealed that the WPU-2 film show an excellent self-healing capability based on the combination of the mobility of the soft segment, dynamic reaction of oxime carbamate bond and hydrogen bonds, and the mechanical properties self-healing efficiency can reach 91.11% after self-healing at 90 °C for 7 h. UV testing and fluorescence imaging results shown that WPU-2 film exhibit a rapid and concentration-dependent response to dimethylamine (DMA), and it also shows varying degrees of response to other organic amines. The WPU-2 film could be readily applied in cold chain transportation of shrimp and fish for real-time and visual monitoring the freshness of seafoods. At the same time, the WPU-2 film could be recycled via hot-pressing and solution casting. Therefore, this strategy provides some insights for preparing multi-functional waterborne polyurethane.
研究领域:
材料科学
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化学工程
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产品关联
DOI
高影响因子
JOURNAL OF CHEMICAL AND ENGINEERING DATA
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2023
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IF 2.6
Xinyi Lü,Xiaotong Yang,Xiaoli Wu,Jidong Wang,Zhong Zhao
In this paper, the solubility of menadiol diacetate in nine alcohols (methanol, ethanol, n-propanol, i-propanol, n-butanol, i-butanol, n-amyl alcohol, i-amyl alcohol, and cyclohexanol) and five n-alkyl acetates (methyl acetate, ethyl acetate, n-propyl acetate, n-butyl acetate, and amyl acetate) was experimentally measured with the aid of a laser dynamic device at temperatures from 283.15 to 323.15 K. The solubility of menadiol diacetate as a function of temperature was regressed in terms of three semiempirical solubility models (Apelblat, van’t Hoff, and λh), two activity coefficient solubility models (Wilson and NRTL), and the Jouyban model. The thermodynamic mixing properties (mixing Gibbs energy, entropy, and enthalpy) of the solutions were estimated in terms of the measured solubility data and the regressed parameters of the Wilson model.
研究领域:
药学
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物理化学
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产品关联
DOI
高影响因子
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
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2013
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IF 2.487
Lingchen Yang,Zhiyong Zhao,Aibo Wu,Yifeng Deng,Zhenlei Zhou,Jianpeng Zhang,Jiafa Hou
A stable and sensitive method has been developed for use in food and livestock product safety for the detection of mycotoxins. This newly developed method allows for the determination of T-2 toxin, HT-2 toxin and diacetoxyscirpenol (DAS) in heart, liver, spleen, lung, kidney, Glandular stomach, muscular stomach, small intestine, muscle, bone and brain samples from broilers using liquid chromatography coupled to tandem mass spectrometry (LC–MS/MS). The samples were initially extracted with ethyl acetate before being filtered through a 0.22 μm nylon syringe filter and subjected to chromatographic separation on a reversed-phase C18 (50 × 2.1 mm, 3 μm) column. A mobile phase composed of 0.1% acetic acid and 10 mM ammonium acetate in methanol and water was used in an assay of the levels of T-2 toxin, HT-2 toxin and DAS. For the analysis of the target compounds, the mass spectrometer was operated under positive electrospray ionization conditions in the selected reaction monitoring mode. The limit of detection was in the range of 0.02–0.05 ng/g, whereas the limit of quantification was in the range of 0.08–0.15 ng/g. The extraction recoveries of spiked samples from the high, intermediate and low levels ranged from 58.5% to 110.5%, and the relative standard deviation (RSD (%)) values were less than 17.0%. The results of inter- and intra-day precision (RSD (%)) were within 14.7%. The results revealed that the present method could be successfully applied to the analysis of T-2 toxin, HT-2 toxin and DAS in the real samples
研究领域:
食品安全
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分析化学
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畜牧学
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DOI
高影响因子
JOURNAL OF HAZARDOUS MATERIALS
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2019
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IF 7.65
Guan-Nan Zhou,Chuan-Shu He,Yi-Xuan Wang,Pan-Pan He,Jing Liu,Yang Mu,Li-Shan Zhang
The removal performance and mechanisms of diatrizoate (DTA), a typical iodinated contrast medium, from water by nano-sized zero-valent iron (nZVI) under aerobic conditions were investigated in this study. Reactive oxygen species (ROS) and transformation products were detected with electron spin resonance and liquid chromatography electrospray ionization tandem mass spectrometry, respectively. Furthermore, the effects of several operational parameters on DTA removal were illustrated. The results showed that nZVI had a much higher DTA removal ability compared to microscale zero-valent iron (mZVI) in the presence of oxygen. Moreover, the detection of ROS and I − as well as the analysis of intermediate products suggested a combination of oxidation and reduction pathways for DTA removal by nZVI under aerobic conditions. Additionally, a high dosage of nZVI and acidic conditions led to the enhancement of DTA removal, while nZVI aging, as well as chloride and nitrate ions in the solution, had negative effects on the degradation of DTA by nZVI in the presence of oxygen.
研究领域:
环境科学
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化学工程
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医学
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DOI
PubMed
高影响因子
Artificial Cells Nanomedicine and Biotechnology
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2016
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IF 2.024
Donglai Qi,Pei Wang,Chen Chen,Song Guo,Xiang Wang
Increasing the size of hemoglobin (Hb) by polymerization offers the benefits of reduced renal clearance and increased duration in the vascular circulation. With this goal, diaspirin cross-linked hemoglobin (DCLHb) was modified in order to keep one thiol group on the surface and then polymerized with 1,6-bismaleimic-hexane (1,6-BMH) to increase the molecular weight. The HPLC results indicated that approximate 20% dimers to tetramers of DCLHb desired were achieved after the polymerization. It was also demonstrated that the oxygen-carrying capacity of the products was similar to natural heme. The present study is expected to improve the efficacy of the DCLHb as an oxygen therapeutic agent.
研究领域:
生物化学
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医学工程
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产品关联
DOI
PubMed
高影响因子
JOURNAL OF MOLECULAR STRUCTURE
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2017
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IF 1.753
Yun Bai,Po Yang,Tao Wang,Yi Gu
This work aims at probing the formation of hydrogen bonds in the blends of polybenzoxazines and additional hydrogen-bond donor moieties-containing compounds. Based on experimental study and computer simulations, we found that the dominant hydrogen bonds of p -cresol-aniline-based dimer ( p C-a-D) and polybenzoxazines (P p C-a) were OH⋯N while N,N ′-(pyridine-2,6-diyl)diacetamide (DAA) was NH⋯O C hydrogen bond. After blending p C-a-D or P p C-a with DAA, additional hydrogen bonds formed, i.e. , OH⋯O C and OH⋯ NH. Moreover, the total quantity of hydrogen bonds of the blends increased. These results suggested that hydrogen bonds formed between polybenzoxazines and the additional hydrogen-bond donor moieties-containing polymers or compounds, and furthermore would be desirable to foster the promoted performance. This novel insight about polybenzoxazine blends is anticipated to help researchers explore more blends of polybenzoxazines with excellent properties.
研究领域:
材料科学
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化学
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DOI
高影响因子
JOURNAL OF HAZARDOUS MATERIALS
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2017
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IF 6.065
Lingjun Meng,Shaogui Yang,Cheng Sun,Huan He,Qiming Xian,Shiyin Li,Guoxiang Wang,Limin Zhang,Dong Jiang
In this study, an electromagnetic induction electrodeless lamp (EIEL) was first introduced into UV advanced oxidation processes (AOPs) for photodegradation of Diatrizoate (DTZ), which was the most persistent iodinated X-ray contrast medium (ICM), and traditional Hg lamps were taken as references. Direct photolysis rate of DTZ under EIEL irradiation was 1.34 times as that under Hg irradiation, but the electric energy consumption was 0.87 times. In this sense, the combination of EIEL and oxidants (O 2 , H 2 O 2 and S 2 O 8 2− (PS)) was further investigated. The remarkably increased photodegradation rates were observed in UV/PS system due to primary contribution rate of SO 4 − (62.5%) based on the results of radical concentrations and second-order rate constants of DTZ with SO 4 − and OH. Inorganic ions influencing the photodegradation process were investigated. The effect of natural organic materials (NOMs) in UV/PS system was studied based on contribution ratios of light screening effect and quenching. Transformation mechanisms of DTZ in UV/PS system included deiodination, intramolecular cyclization, decarboxylation, deacetylation and deamination, which were further confirmed by frontier electron density calculations. The study indicated that UV/PS with EIEL irradiation has the potential to remove pharmaceuticals in contaminated aquatic environments.
研究领域:
环境科学
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化学工程
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水处理技术
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产品关联
DOI
PubMed
高影响因子
Phytochemistry Letters
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2024
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IF 1.3
Xi-Long Guo,Chun-Yan Zhao,Cui-Ping Zhang,Yi Zhu,Qing-Rong Wu,Yuan-Qing Zhou,Ya-Hong Fei,Fang Ge,Wei Shi
In this letter, we reported synthesis of 2,4-Diacetylphloroglucinol (DAPG) derivatives as a new class of anti fungal agents . A series of DAPG ester analogues with diverse length of acyl substitution on aromatic hydroxyls were synthesized and characterized by 1 H, 13 C NMR and ESI-MS. Their antifungal activities were evaluated in vitro against six important plant fungal pathogens using mycelial growth inhibitory rate assay. A clear structure-activity relationship (SAR) study of the diacylphloroglucinols was investigated. Compounds 2 , 2a - d , 2i , 2j and 2k exhibited broad-spectrum anti fungal activity, in addition, the anti fungal activity was correlated with the lipid-water partition coefficient of the compounds (log P ), these active analogues have log P between − 0.53 and 0.19. Particularly compound 2k (log P 0.19) was found active to Glomerella cingulata with IC 50 value of 1.26 μ g/mL; compound 2 (log P − 0.51) was identified the most active one against Pyricularia oryzaecar (IC 50 1.52 μ g/mL). The results suggest that compound 2 and 2k might be promising candidates in the development of new pesticides.
研究领域:
植物化学
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农药学
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微生物学
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产品关联
DOI
高影响因子
MICROCHEMICAL JOURNAL
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2024
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IF 4.9
Qi Wang,Xiaoxia Bai,Fei Liu,Peipei Li,Qianlin Tang
Early diagnosis of cancer is crucial to effective treatment of the patients and to higher survival rates. Tumor marker detection as an effective and noninvasive cancer diagnosis method has important clinical significance. N 1 , N 12 -diacetylspermine (DAS) is a new tumor marker. The development of its detection methods is an urgent need for medical diagnosis and human health monitoring. The conventional detection methods of DAS are labor-intensive and time-consuming approaches. In this work, a novel electrochemical detection platform was established by integrating an organic electrochemical transistor (OECT) with a microfluidic chip and applied for trace measurement of DAS. The sensing unit is a gate electrode in the OECT modified with molecularly imprinted polymers (MIPs), which can be used as an artificial receptor to realize label-free detection. The high specific recognition ability of MIPs films combined with the amplified function of an OECT yielded a highly sensitive and selective electrochemical detection chip. The integrated microfluidic channel controlled the exact amount of solution to be delivered and provided real-time detection of DAS. The experimental results indicated that changes in channel current was proportional to DAS concentrations from 1 nM to 10 μM, with the detection limits of 0.8 nM. It is the first demonstration of the integration of a microfluidic system with a MIP-gated OECT for real-time tumor marker detection. The study results of this work helped to develop Point-Of-Care (POC) tools for the early diagnosis of lung cancer, colon cancer and breast cancer.
研究领域:
生物医学工程
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分析化学
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癌症诊断
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产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）