Materials Science & Engineering C-Materials for Biological Applications
·
2016
·
IF 3.42
Jie Fei,Ran Liu
Wiping out counterfeit drugs is a great task for public health care around the world. The boost of these drugs makes treatment to become potentially harmful or even lethal. In this paper, biodegradable drug-laden QR code label for anti-counterfeiting of drugs is proposed that can provide the non-fluorescence recognition and high capacity. It is fabricated by the laser cutting to achieve the roughness over different surface which causes the difference in the gray levels on the translucent material the QR code pattern, and the micro mold process to obtain the drug-laden biodegradable label. We screened biomaterials presenting the relevant conditions and further requirements of the package. The drug-laden microlabel is on the surface of the troches or the bottom of the capsule and can be read by a simple smartphone QR code reader application. Labeling the pill directly and decoding the information successfully means more convenient and simple operation with non-fluorescence and high capacity in contrast to the traditional methods.
研究领域:
药学
·
材料科学
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DOI
PubMed
高影响因子
JOURNAL OF COLLOID AND INTERFACE SCIENCE
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2022
·
IF 9.965
Bo Zhang,Shanshan Li,Yuan Wang,Yonggang Wu,Hailei Zhang
With the evolution of information technology, the development of smart materials for the information storage and encryption is in urgent need. Herein, halloysite nanotubes (HNTs)-based self-healing hydrogels were facilely prepared by using aryl arylboronic acid-bearing tetraphenylethylene (TPE) as crosslinker agent, in which the HNTs were covalently bonded into the polymeric matrix. With the addition of HNTs, the obtained hydrogel (H2) shows improved compression resistance performance and self-healing property, which can be customed in certain shapes. The TPE-crosslinked hydrogels (H1 and H2) are able to emit bright blue fluorescence centering at 457 nm when exposed to 365 nm light. By holding together with 1,4-phenylenebisboronic acid-crosslinked hydrogels (H3) with non-fluorescence property, the obtained cube is able to store UV-sensitive QR code information which is potentially to be recognized by QR code scanner or other smart tools.
研究领域:
材料科学
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信息加密技术
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DOI
PubMed
高影响因子
POLYMER
·
2019
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IF 3.771
Yulin Zhang,Yueshan Li,Kaixuan Chen,Zixun Ma,Xiangdong Wang,Lingying Shi,Rong Ran
With the rapid development of mobile networks and smartphones, quick response (QR) code has been more and more applied to various fields. Many individuals also have a QR code containing their own information. But because of its low cost and easy imitation, the QR code not only facilitated people's life but also brought the risk of revealing personal privacy. Therefore, it is very necessary to improve the security of the QR code by some simple encryption methods. Herein, by combining self-healing hydrogel and thermos-sensitive hydrogel, multifunctional dual network hydrogel with good mechanical properties , self-healing ability, and fast temperature sensitivity was synthesized. Moreover, customized patterned thermos-sensitive hydrogels can be obtained by the simple assembly. And the patterns can be triggered by human body temperature and disappeared after cooling at room temperature . Based on these performances, a QR code hydrogel with low cost, accessibility, durability and security features was fabricated for the storage and display of information. And this simple strategy is of universal significance for the synthesis of multifunctional and high-performance hydrogels.
研究领域:
材料科学
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生物医学工程
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产品关联
DOI
高影响因子
INTERNATIONAL JOURNAL OF PHARMACEUTICS
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2023
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IF 5.8
Wenrui Yan,Jintao Shen,Dongdong Liu,Jingfei Li,Yupeng Wang,Bin Feng,Yiguang Jin
3D printing is used in manufacturing of personalized and customized medications. Moreover, information technology has been integrated with 3D printing, which builds the basis of informative medications. Here, clonidine hydrochloride (CH) was formulated in informative wafers (info-wafers) by combination of 3D printing, code design and photopolymerization. Braille code (recognized by blind persons), bar code, and quick response (QR) code were used for the design of info-wafers. A code positive mold was 3D-printed with rigid resins by stereolithography, which was transformed to the silicone negative mold by thermal polymerization. A homogeneous CH suspension in N -vinyl pyrrolidone was casted into the negative mold followed by photopolymerization to form CH info-wafers. The bulgy parts of info-wafers were painted with edible ink except for Braille code info-wafers. The CH in info-wafers maintained the amorphous state, which was demonstrated by X-ray diffraction. The amorphous CH had rapid dissolution. Bar code info-wafers were scanned by smartphone though only simple information was obtained. QR code info-wafers were smartphone-scanned to link a website that contained sufficient information such as the instruction of CH application and the collection of patient information. Info-wafers provide online drug information and use instructions for patients to make the treatment standardization and normalization.
研究领域:
制药工程
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药物制剂
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信息技术与医药结合
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产品关联
DOI
PubMed
高影响因子
Nanoscience and Nanotechnology Letters
·
2019
·Vol. 11
·期 4
·451-463
·
IF 0
Yang Ling,Wang Zhengxiang,Fan Shuhong,Feng Jianxiang,Zhong Yunfei,Zhao Tian,Hu Yaojian,Liu Yuejun
The smartphone recognition of color halftone quick response (QR) codes with upconversion luminescence was demonstrated, where the codes, with excellent reliability and attractive appearance, were achieved via high-quality gravure printing of hexagonal phase (β-) NaYF4
crystals. Firstly, the three-primary-color (RGB) waterborne upconversion inks were formulated by incorporating the synthesized β-NaYF4 crystals with excellent dispersion and corresponding emission signals. The secondary colors (yellow, magenta, and cyan) and tertiary
colors (white and black), with accurate chromaticity, were garnered in accordance with the additive color synthesis. Then the color halftone QR codes could be generated by embedding regular QR codes into pre-defined halftone images as ciphertexts. Produced by independent deposition of the
RGB inks via high-quality gravure printing, the color halftone QR codes were invisible under ambient condition, while presented bright multi-color halftone patterns upon near-infrared (NIR) irradiation. The ciphertexts could be decoded with a common smartphone under the 980 nm excitation for
the authenticity verification. The developed technology offered significant advantages in multiple anti-counterfeiting, tracking, and visual effects, particularly possessing merits in the respect of low cost, high throughput, excellent concealment, and pro-environment, paving the way for the
upconversion materials in the anti-counterfeiting application.
研究领域:
材料科学
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光学
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防伪技术
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DOI
CHEMICAL ENGINEERING JOURNAL
·
2025
·
IF 13.2
Chengwei Xiao,Haixian Shi,Hao Zhong,Chengbin Zou,Yiyong Chen,Jinru Li,Weien Liang,Wanying Zhang,Dezhi Zhan,Shilong Zhong,Rui Chen,Zhaoxiang Zhu,Cheng Wang,Yujie Chen,Xudong Chen
Holographic images based on surface relief gratings are widely used in anti-counterfeiting labels for their high image resolution, full-color display and durability. However, traditional polymer-based holographic anti-counterfeiting labels are faced with the risk of being counterfeited due to the simple grating structures, and cannot provide further verification information except for dynamic optical effects. Moreover, in extreme environments, such as high / low temperatures, polymer-based holographic anti-counterfeiting labels may lose their encrypted information due to thermal / cold deformation. Therefore, developing one smart holographic label that is easy to read, difficult to replicate, and durable is a challenge. Herein, we propose a strategy of reconstructing quick response (QR) code on polyimide films through holographic relief gratings. And by utilizing the structural characteristics of QR code and multiplexing technology, we have achieved the integration of multiple authentication information access entrances without crosstalk at the same location. The applicability and superiority of switchable holographic QR codes that combine anti-counterfeiting and information traceability in encryption applications are discussed. This strategy for integrating encryption information based on surface relief grating provides an effective alternative for the manufacture of temperature-tolerant polymer-based smart holographic anti-counterfeiting labels.
研究领域:
光学安全
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材料科学
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信息加密
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聚合物技术
·
纳米制造
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产品关联
DOI
高影响因子
Advanced Science
·
2024
·
IF 14.3
Yijun Zhao,Xingru Yang,Lun Yang,Fangjian Xing,Cihui Liu,Yunsong Di,Guiyuan Cao,Shibiao Wei,Xifeng Yang,Xiaowei Zhang,Yushen Liu,Zhixing Gan
The smart materials with multi-color and stimuli-responsive luminescence are very promising for next generation of optical information encryption and anti-counterfeiting, but these materials are still scarce. Herein, a multi-level information encryption strategy is developed based on the polychromatic emission of Sb-doped double perovskite powders (SDPPs). Cs 2 NaInCl 6 :Sb, Cs 2 KInCl 6 :Sb, and Cs 2 AgInCl 6 :Sb synthesized through coprecipitation methods exhibit broadband emissions with bright blue, cyan, and orange colors, respectively. The information transmitted by specific SDPP is encrypted when different SDPPs are mixed. The confidential information can be decrypted by selecting the corresponding narrowband filter. Then, an encrypted quick response (QR) code with improved security is demonstrated based on this multi-channel selection strategy. Moreover, the three types of SDPPs exhibit three different water-triggered luminescence switching behaviors. The confidential information represented by Cs 2 NaInCl 6 :Sb can be erased/recovered through a simple water spray/drying. Whereas, the information collected from the green channel is permanently erased by moisture, which fundamentally avoids information leakage. Therefore, different encryption schemes can be designed to meet a variety of encryption requirements. The multicolor and stimuli-responsive luminescence greatly enrich the flexibility of optical information encryption, which leaps the level of security and confidentiality.
研究领域:
材料科学
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光学
·
密码学
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产品关联
DOI
PubMed
高影响因子
ACS Applied Materials & Interfaces
·
2025
·
IF 8.2
ZIN MAR OO,Jiurong Li,Wenxuan Sun,Guanchao Yin,Xiao Gong
The growing sophistication of counterfeit technologies necessitates the development of innovative security materials with enhanced protection capabilities. This study presents a one-pot solvothermal synthesis of multicolor fluorescent inks based on boron and nitrogen codoped carbon nanodots (B, N-CDs) with blue, green, and yellow emissions. The emission wavelengths are modulated through precursor selection and reaction condition optimization, resulting in emissions at 440, 520, and 540 nm, respectively. Detailed structural and optical analyses reveal that the fluorescence shift is related to doping levels and particle size, as confirmed by XPS, FTIR, TEM, and PL lifetime analysis. The synthesized B, N-CDs were formulated into inks suitable for both handwriting and screen-printing applications. Under ambient light, the patterns are nearly invisible but exhibit strong multicolored fluorescence when illuminated with ultraviolet (UV) light at 365 nm. Practical demonstrations such as QR code printing, product authentication tags for luxury goods, and Morse code encryption confirmed the potential of these inks for secure labeling and information encryption. Additionally, the inks exhibited excellent stability under various environmental stresses including UV radiation, mechanical abrasion, humidity, solvents, and temperature fluctuations. These features position B, N-CD-based fluorescent inks as a cost-effective and robust solution with strong potential for scalable production in advanced anticounterfeiting and information encryption technologies.
研究领域:
材料科学
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纳米技术
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光学工程
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安全印刷
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信息技术
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ACS Applied Materials & Interfaces
·
2021
·
IF 9.229
Man Li,Yifei Zhao,Shuai Zhang,Ruirui Yang,Weidong Qiu,Pin Wang,Maxim S. Molokeev,Shi Ye
The photoinduced reversible ion exchanges in mixed halide perovskites and the resulting luminescent variations make them promising for constructing anti-counterfeiting patterns; however, its understanding in an interfacial view is lacking. In this work, nominal CsPbBr1.5Cl1.5 (CPBC) nanocrystals (NCs) were introduced into macroporous Y2O3:Eu3+ (MYE) to realize emission color variations from red emission of MYE to green emission of halide NCs. The large surface area of MYE helps the formation of Y–Cl/Br bonds which induces fluctuation in the halide composition, while water and intrinsic halogen defects have also been proved to be essential in the reversible ion segregation process. The PL variations of several samples with different pore sizes were investigated upon irradiation of light with different photon energies and excitation power at certain temperatures. According to combined results of density functional theory calculation, the research reveals the presence of two energy barriers that would be overcome correspondingly by the excitation photon and the concentration difference in the ion exchange and recovery process. A photochromic anti-counterfeiting quick response (QR) code was constructed facilely with the perovskite composites. This work provides a deeper understanding from the interfacial aspect and also proposes a feasible strategy to realize reversible PL variation for anti-counterfeiting applications.
研究领域:
材料科学
·
光学
·
纳米技术
·
防伪技术
✓ 已验证
DOI
PubMed
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2025
·
IF 13.2
Mingyang Chen,Yaxuan Lu,Renata Solarska,Ming Li
The insect vision systems mainly rely on the apposition compound eyes (CEs) with the omnidirectional light-harvesting and wide-angle sensing abilities for prey recognition and enemy defense. Thus, the insect CEs become a compelling source of inspiration for the development of optoelectronic devices and optical sensors. Herein, inspired by the insect CEs, a biomimetic plasmonic CE biosensor is reported with excellent omnidirectional plasmonic properties for on-particle label-free surface-enhanced Raman spectroscopy (SERS) multiplexed detection of biomarkers. Our biosensor consists of a closely-packed polystyrene microsphere monolayer covered with a dense layer of vertically aligned Au nanowires (v-Au NWs). The omnidirectional distribution of v-Au NWs on the curved surface endows the plasmonic CE biosensor with angle-independent plasmonic responses and uniform SERS signals, verified by our experimental investigations and numerical simulations. Based on the intrinsic SERS fingerprints and dense electromagnetic “hotspots”, the present plasmonic CE biosensor is demonstrated with high sensitivity and excellent selectivity for simultaneous on-particle label-free SERS detection of uric acid, folic acid and adenine oligomer. Moreover, the composition and concentration information of the complex samples integrated in the SERS images is recorded in a smartphone-readable QR code, highlighting its practical potential for label-free SERS multiplexed biosensing.
研究领域:
生物传感器
·
纳米光子学
·
光学传感
·
分析化学
·
生物医学工程
·
材料科学
✓ 已验证
产品关联
DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2024
·
IF 13.3
Zi-Rong Li,Tian-Run Lv,Zhenxu Yang,Wen-Hai Zhang,Ming-Jie Yin,Ken-Tye Yong,Quan-Fu An
Stretchable strain sensors have the potential to significantly advance electronic healthcare (E-healthcare). However, current challenges, including a limited detection range, low sensitivity, aggregation of conductive nanoparticles, and the inherent rigidity of conductive polymers within hydrogel matrices, hinder their progress. In our study, we employed a dual approach: we tailored both physical and chemical bond densities and coupled them with conductive polymer nanoparticles. As a result, we developed a stretchable hydrogel strain sensor embedded with a quick response code. This innovation achieved an impressive detection range of up to 1500% and a high gauge factor of 16.6. By modifying the hydrogen bond strength and converting conductive polymer nanoparticles into linear polymer chains, we managed to enhance the sensor's stretchability to 2100%. Moreover, the incorporation of a quick response code enabled the sensor to simultaneously monitor in real-time and encode information. Thus, our sensor emerges as a robust contender for pioneering advancements in E-healthcare, potentially supporting intricate applications like rehabilitation progression tracking.
研究领域:
材料科学
·
生物医学工程
·
传感器
·
医疗技术
✓ 已验证
产品关联
DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2021
·
IF 13.273
Po Hu,Shuai Zhou,Yang Wang,Jianhua Xu,Sa Zhang,Jiajun Fu
The luminescent self-healing materials have a significant prospect in optical device applications such as biosensing, multicolor displays, and high-level anti-counterfeiting. Herein, a novel printable, room-temperature self-healing and full-color-tunable luminescent composites were developed through the noncovalent binding of physically cross-linked p(HFBM- co -SBMA)/EMITFSI and excitation-orthogonalized RGB-switchable UCNPs. According to a strategy of Selective photon capture (SPC), the RGB-switchable core-sextuple-shell UCNPs were first established for red/green/blue-switchable luminescence under three different excitations (980/808/1550 nm) and even full-color output through the combination of 980/808/1550 nm light. The copolymer p(HFBM- co -SBMA), pre-synthesized via free radical polymerization, was incorporated with ionic liquid EMITFSI to formulate room-temperature self-healing material owing to ion–dipole interactions between EMITFSI and p(HFBM- co -SBMA). Afterward, the integration of 30 wt% EMITFSI copolymer and fluothane-modified UCNPs resulted in the formation of the final full-color-tunable luminescent self-healing composites, which not only exhibited superior Young’s modulus and healing efficiency than some previously reported room-temperature self-healing materials, but also realized full-color-tunable emissions under ternary 980/808/1550 nm excitations. Significantly, the luminescent self-healing composites, which also exhibited colorless character and high transmittance, could be employed as printable inks for making various luminescent patterns (including clock, flower, and QR code) on flexible substrates via convenient and cost-effective screen-printing technique. As the results of proofs of concept, these luminescent patterns displayed fantastic viewing capability and highly secured property, which showed enormous potential of the proposed luminescent self-healing composites in flexible panchromatic display and high-security-level anti-counterfeiting. To our knowledge, this work provides the strategy for constructing full-color-tunable self-healing luminescent composites for the first time. Undoubtedly, the well-designed luminescent self-healing materials will provide new insights and guidance for exploiting the new generation of flexible optical devices, especially multicolor displays and anti-counterfeiting devices.
研究领域:
材料科学
·
光学
·
纳米技术
·
显示技术
·
防伪技术
✓ 已验证
DOI
高影响因子
危险品化学品经营许可证（带存储）