COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
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2020
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IF 3.99
Shiqi Weng,Ming Jin,Decheng Wan
A facile way to fabricate a pH-stable, durable, and porous material with active amines (NHx, x= 1,2)-derived diol groups on a pore surface is reported. Branched polyethyleneimine (PEI) in water forms a supramolecular complex with sodium dodecyl benzene sulfonate (SDBS), and this complex acts as an emulsifier . For the microcrystal cellulose (MC)-dispersed aqueous solution of PEI, SDBS is charged to turn the mixture into a medium internal phase air–in–water (A/W) emulsion upon oscillation. The emulsion is solidified by the partial crosslinking of PEI with polyethylene glycol diglycidyl ether (0.2 eq. of PEI NH groups) and further developed into an open-cellular monolith by removing the SDBS and water in the system. Under optimized conditions [pH 10, PEI at 20 % in water, and MC/PEI (50 % mass ratio)], the porous monolith (MC@PEI) shows a specific surface area of up to 14.9 m 2 g −1 . The amino groups are easily transformed into diols by treating with glycidol , and the resulting MC@PEI-diol can act as a scavenger to extract the trace boric acid in water. The adsorption follows the Langmuir model and shows chemical adsorption character with a boron-loading capacity of up to 2.68 mmol g −1 . Presaturing the scavenger with anionic dyes (488 mg g −1 ) exerts limited impact on the loading ability of BA. Additionally, the scavenger combines chemical stability in the absence of pH-labile bonds and mechanical durability for the composite structure with rigid MC skeleton and flexible PEI muscle.
研究领域:
材料科学
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环境科学
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DOI
高影响因子
ADVANCED FUNCTIONAL MATERIALS
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2015
·Vol. 25
·期 25
·3847-3854
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IF 11.805
Xiangyang Zhu,Jinlou Gu,Junying Zhu,Yongsheng Li,Liming Zhao,Jianlin Shi
Introduction of accessible boronic acid functionality into metal–organic frameworks (MOFs) might to endow them with desired properties for potential applications in recognition and isolation of cis -diol containing biomolecules (CDBs). However, no investigation is found to address this topic until now. Herein, Cr-based MOFs of MIL-100 (MIL stands for Materials from Institut Lavoisier) integrated with different pendent boronic acid group (MIL-100-B) are reported. This new functional material is successfully prepared using a simple metal–ligand–fragment coassembly (MLFC) strategy with isostructure to the parent MIL-100 as verified by X-ray diffraction characterization. The integration and content tunability of the boronic acid group in the framework are confirmed by X-ray photoelectron spectroscopy and 11 B NMR. Transmission electron microscopy reveals that MIL-100-B can evolve into well-defined morphology and nanoscale size at optimized boronic acid incorporating level. The obtained MOFs exhibit comparable surface areas and pore volumes with parent MIL-100 and present exceptional chemical stability in a wide pH range. The inherent boronic acid components in MIL-100-B can effectively serve as the recognition units for the cis -diol moieties and consequently enhance the capture capabilities for CDBs. The exceptional chemical stability, high porosity, and good reusability as well as the intrinsic cis -diol moieties recognition function prefigure great potential of the current MIL-100-B in CDBs purification, sensing, and separation applications.
研究领域:
材料科学
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生物化学
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DOI
高影响因子
Journal of Materials Chemistry B
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2019
·Vol. 7
·期 22
·3576-3581
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IF 5.047
Xianqi Feng,Jun Xu,Yanxia Liu,Wenpeng Zhao
In this study, a novel and facile glucose detection system based on inverse opal hydrogels (IOHGs) was developed. Based on the intuitive structural colour, the gel sensors could be used for the detection of carbohydrates containing 1,2-cis-diol groups and diagnosis of diabetes without the assistance of sophisticated analysis instruments. Compared to the case of traditional opal sensors, the stable network structure of the IOHG samples endowed them with reusability for multiple times, which could suffer 10 cyclic detections without any reduction in sensitivity; possessing the combined advantages of high sensitivity, a stable network, and easy processing, IOHGs might open up a new avenue and propose a promising prospect in the detection and identification of diverse organic compounds.
研究领域:
生物传感
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材料科学
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医学诊断
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DOI
高影响因子
Journal of Materials Chemistry B
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2024
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IF 6.1
Xiuli Wang,Leyi He,Yaoxia Li,Jia Guo,Changchun Wang
High-sensitivity detection of biomarkers in biological samples is crucial for the early diagnosis and treatment of diseases. In this paper, a versatile and flexible immobilization technique based on the specific affinity interaction between boronic acid and cis-diol groups of antibodies was developed for biomarker detection. As a model, the boronic acid-modified immunomagnetic beads were used for facile and quick immobilization of the alpha-fetoprotein (AFP) antibody due to the specific affinity interactions. Based on this new class of immunomagnetic beads, the chemiluminescence immunosensor could efficiently detect the biomarker of AFP. Under optimal conditions, the limit of detection (LOD) is as low as 8 fM (S/N = 3), showcasing superior sensitivity and detection specificity for AFP. Subsequently, the system was successfully applied to the detection of AFP in fetal bovine serum samples, and the average recovery rate is greater than 95%. Its performance surpassed that of commercial immunomagnetic beads, showcasing the potential application of this new strategy for bioanalysis and clinical diagnosis.
研究领域:
生物医学工程
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分析化学
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临床诊断
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产品关联
DOI
PubMed
高影响因子
INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
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2015
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IF 2.587
Xi Chen,Guangfa Zhang,Qinghua Zhang,Xiaoli Zhan,Fengqiu Chen
Antifouling (AF) coatings have been a research focus on effectively resisting biocontamination of equipment applied in the aquatic environments. The amphiphilic ternary copolymers P(H–P–A) composed of N-(4-hydroxy-3-methoxybenzyl)acrylamide (HMBA), poly(ethylene glycol) methyl ether methacrylate, and 2-hydroxyethyl acrylate were synthesized by free-radical polymerization. Then the polyurethane (PU) copolymer coatings with capsaicin and poly(ethylene glycol) (PEG) moieties were prepared by cross-linking with polymeric phenyl methanediisocyanate. Fourier transform infrared and 1H NMR were employed for chemical structural analysis of the products. The surface composition and concentration of nitrogen atoms on the copolymer films were quantitatively analyzed by X-ray photoelectron spectroscopy. The AF properties of the copolymers were assessed by static protein adsorption and antibacterial tests. The targeted copolymer film samples can achieve an average antibacterial efficiency of 93.3% and a protein-resistant rate of 97.3%, which demonstrated that P(H–P–A) is a potential environmentally friendly material for AF application.
研究领域:
材料科学
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聚合物化学
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生物医学工程
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环境科学
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产品关联
DOI
高影响因子
JOURNAL OF CHROMATOGRAPHY A
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2021
·
IF 4.759
Yang Zhao,Jing Wang,Yang Yang,Qing Fu,Yanxiong Ke
In this work, mesoporous silica microspheres with bimodal porous structures for size exclusion chromatography (SEC) supports were synthesized via a pseudomorphic transformation method by using 3.5 and 5 μm commercial silica particles as sources and cetyltrimethylammonium bromide (CTAB) as a template. The effects of the synthetic conditions on the pore size distribution were examined, including the temperature, reaction time and the molar ratio of SiO 2 :NaOH. Bimodal porous silicas (BPSs) with pore sizes of 3.01 and 12.80 nm were obtained with SiO 2 :NaOH:CTAB:H 2 O=1:0.1:0.1:20 at 80 °C for 24 h. The BPSs were bonded with diol groups to produce a stationary phase for SEC. The column performance was evaluated with three types of samples, namely, dextran (70 KDa-62 Da), polyethene glycol (PEG) (20 KDa-32 Da) and three biomolecules (36 KDa-1.36 KDa). The column that was packed with a 3.5 μm stationary phase showed excellent resolution for molecular weights of less than 1 KDa with high column efficiency. Carbohydrate samples (dextran (MW=1296), dextran (MW=972), sucrose (MW=342), glucose (MW=180) and glycerol (MW=92)) were separated. Heptaethylene glycol, hexaethylene glycol, pentaethylene glycol, tetraethylene glycol, triethylene glycol, and diethylene glycol were resolved in a PEG200 sample. In summary, this work shows the advantages of bimodal mesopores in SEC for small molecules less than 1 kDa. In the pseudomorphic synthesis, the pore size can be regulated by template micelles. Thus, the development SEC supports with high accuracy for a specified molecular weight range is expected since the pore size can be regulated by the surfactant template.
研究领域:
材料科学
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分析化学
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纳米技术
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产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）