SPECTROSCOPY LETTERS
·
2013
·
IF 0.667
Pingping Li,Jing Song,Yizhong Shen,Youqiu He
Aqueous glutathione-capped cadmium/tellurium quantum dots with a diameter of about 3 nm were synthesized. The fluorescence was quenched in the presence of protoporphyrin IX disodium salt, with the excitation wavelength at 320 nm. Under the optimal conditions, the quenched fluorescence intensity was linear in the range of 0.096–16 µg · mL−1 with a concentration of protoporphyrin IX disodium salt, and the detection limit (3σ) was 2.8 × 10−2 µg · mL−1. The proposed method has been applied to the determination of protoporphyrin in serum samples with satisfactory results. The interaction mechanism was investigated.
研究领域:
分析化学
·
生物医学
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产品关联
DOI
高影响因子
MACROMOLECULES
·
2025
·
IF 5.2
Mengen Zhang,Ruijia Wang,Tinghao Jia,Congjing Ren,Jingdai Wang,Yongrong Yang,Yao Yang
A molecular-level understanding of the ion cluster morphology is crucial to designing the structure and enhancing the properties of random polyethylene ionomer. Here, we report that the strategic addition of aliphatic disodium salt has a pronounced effect on the mechanical properties and nanoscale morphology. With the addition of various aliphatic disodium salts, both the tensile strength and Young’s modulus are significantly increased. By comparing the results of atomistic molecular dynamics simulations with experimental characterization data, the ionic cluster nanoscale morphology varies with different chain-length disodium salts, while maintaining the crystallization of the polyethylene matrix. The alkyl disodium salts with relatively short alkyl chains (C12) bridge between clusters by anchoring to two different clusters, helping to redistribute the clusters within the polymer matrix and providing additional cross-link strength. The cluster morphological evolution during stretching was simulated, and its relation to mechanical properties is comprehensively discussed. This, in turn, unlocks the potential for structural regulation at the nanoscale by additive manufacturing to enhance the performance.
研究领域:
材料科学
·
高分子化学
·
计算化学
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产品关联
DOI
高影响因子
MOLECULES
·
2022
·Vol. 27
·期 22
·7947
·
IF 4.927
Qingmei Sun,Yawen Hong,Zhaoxu Yang,Peixia He,Chao Chen,Jincheng Wang,Qinjie Weng
Pyrroloquinoline quinone (PQQ) is a powerful antioxidant coenzyme existing in diet, benefiting growth, development, cognition function, and the repair of damaged organs. However, a method for detecting PQQ in vivo was rarely described, limiting the research on the bioanalysis and metabolic properties of PQQ. In this study, a novel, simple, and efficient ultra-high performance liquid chromatography/tandem mass spectrometry (UPLC-MS/MS) method was developed and validated to quantify the concentration of PQQ in rat plasma. Detection through mass spectrometry was operated by multiple reaction monitoring (MRM) in negative electrospray ionization mode with ion transitionsm/z328.99→197.05 for PQQ andm/z280.04→195.04 for the internal standard. The calibration curves were linear up to 10,000 ng/mL, with a lower limit of quantitation of 10 ng/mL. Inter-run and intra-run precision ranged from 1.79% to 10.73% and accuracy ranged from −7.73% to 7.30%. The method was successfully applied to a toxicokinetic study in Sprague–Dawley rats after the oral administration of PQQ disodium salt at doses of 250 mg/kg, 500 mg/kg, and 1000 mg/kg. The toxicokinetic parameters were subsequently analyzed, which may provide valuable references for the toxicokinetic properties and safety evaluation of PQQ.Keywords:PQQ disodium salt;UPLC-MS/MS;toxicokinetic;rat plasma
研究领域:
分析化学
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毒理学
·
药代动力学
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产品关联
DOI
PubMed
高影响因子
Materials Today Chemistry
·
2022
·
IF 7.613
D. Meng,Y. Li,P. Qi,J. Sun,X. Gu,H. Li,Z. Wang,S. Zhang
The fire hazard posed by the inherent flammability and smoke toxicity of flexible polyurethane foam (FPUF) often necessitates the incorporation of flame retardants to meet stringent regulations. The development of environmentally friendly strategies to enhance the fire resistance of FPUF is of increasing importance and a significant amount of research has been devoted to this end. In this work, a bio-based coating was constructed by co-depositing polydopamine and guanosine 5′-monophosphate disodium salt (GMP) to increase the fire safety of FPUF. The coating significantly improved the flame retardancy of FPUF. The FPUF@PDA-GMP samples showed an LOI value of 24.5% with a self-extinguishing effect and exhibited reduced release of heat, smoke, CO, CO 2 , and HCN due to their compact and strong char. The compressive strength at 70% strain of FPUF@PDA-GMP was 8 times higher than that of the control FPUF sample. The coating had a little negative effect on the resilience and improved its elongation at break. This investigation has provided a useful method for designing and producing high-performance foams.
研究领域:
材料科学
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环境科学
·
化学工程
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产品关联
DOI
高影响因子
ENERGY & FUELS
·
2025
·
IF 5.3
Kunlin Ma,Dongliang Li,Jingsheng Lu,Decai Lin,Deqing Liang
The high toxicity, excessive foaming, and wall-climbing behavior of traditional promoters limit their large-scale use in hydrate-based gas storage and separation. Environmentally friendly and efficient hydrate management strategies are needed. We used a sapphire cell for comparative analysis of kinetic dynamics and wall-climbing morphology during hydrate formation under sugar alcohol (SA) and erioglaucine disodium salt (EDS). Microscopic analyses explored the mechanisms of EDS and SA on hydrate formation, with comparisons to amino acids. This is the first report on the synergistic effects of SA and EDS, both of which exhibit excellent biocompatibility and degradability, not only in significantly enhancing hydrate formation but also in regulating hydrate wall-climbing behavior. Three distinct modes of hydrate wall-climbing were observed at varying concentrations of EDS and SA. At a concentration of 4 ppm EDS + SA, hydrates exhibited an “antenna growth” mode, characterized by delayed promotion and a significantly prolonged induction time compared to the film formation time. In contrast, 200 ppm EDS + SA demonstrated a strong synergistic effect, drastically reducing both film formation and induction times. Microscopic characterizations revealed that while EDS + SA enhanced the selectivity of the hydrate for CO2, it did not alter the hydrate cage structure. Optical microscopy results further demonstrate that EDS + SA can inhibit the capillary growth of hydrates and alter their crystal morphology. These findings suggest a mechanism in which a hydrophobic skeletal network promotes hydrate formation and regulates wall-climbing behavior. The EDS + SA combination holds promise for large-scale hydrate applications, offering efficient promotion and wall-climbing control.
研究领域:
化学工程
·
环境科学
·
材料科学
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产品关联
DOI
高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
·
2020
·
IF 7.1
Jinli Li,Lei Jiao,Weiqing Xu,Hongye Yan,Guojuan Chen,Yu Wu,Liuyong Hu,Wenling Gu
Glutathione (GSH) plays a significant role in various biological functions. The fluctuation of GSH level is closely linked to some serious diseases. Currently, the colorimetric detection of GSH is mainly built on the inhibitory effect on the catalytic activity of the developed nanomaterials . However, tedious synthesis of the nanomaterials is always required to control their morphologies for better catalytic activity. Metal indicators are some specific substances capable of chelating metal ions, during which significant color variation can be triggered, making them promising for colorimetric analysis. More importantly, the recognition of metal ions has nothing to do with the structure of the materials. Herein, CoOOH ultrathin nanosheets were prepared via a facile method, which can be easily reduced to Co 2+ ions by GSH. After being chelated by metal indicator, a rapid and sensitive sensing platform for GSH detection is established with the distinct color change. As a result, the UV–vis absorbances of Co 2+ –xylenol orange disodium salt complexes (a typical metal indicator) at 580 nm exhibit good linearity against GSH concentrations from 33 μM to 1.3 mM with the detection limit of 13.7 μM. The developed sensor is further used in the detection of GSH contained in the human serum and an ideal recovery rate is obtained, demonstrating its excellent applicability for the detection of GSH in practical samples.
研究领域:
分析化学
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纳米技术
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生物传感器
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生物医学工程
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产品关联
DOI
高影响因子
AICHE JOURNAL
·
2017
·Vol. 64
·期 3
·993-1000
·
IF 2.836
Huimin Liu,Yuliang Jiang,Jincheng Ding,Wenhui Shi,Jiefeng Pan,Congjie Gao,Jiangnan Shen,Bart van der Bruggen
Surface modification of anion exchange membranes (AEMs) by attaching a negatively charged layer is the main method for preparing monovalent anion selective membranes. However, tremendous increase of membrane resistance and poor long-term stability of the modified membranes face great challenges. In this work, a photosensitive molecule (4,4-diazostilbene-2,2-disulfonic acid disodium salt [DAS]) was infiltrated into the membrane surface and immobilized in the structure by cross-linking under UV irradiation. This method introduced negative charge to the surface layer of the AEMs without increasing membrane thickness, leading to high performance membrane with high monovalent anion selectivity. The optimized membrane (D-5) shows the highest perm-selectivity of 11.21, which is superior to the commercial selective membrane Selemion ® ASV and previously reported monovalent anion selective AEMs. Furthermore, the newly developed membrane exhibits excellent long-term stability, which can maintain constant selectivity during the 80 h ED experiment. © 2017 American Institute of Chemical Engineers AIChE J , 64: 993–1000, 2018
研究领域:
化学工程
·
材料科学
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产品关联
DOI
高影响因子
JOURNAL OF APPLIED POLYMER SCIENCE
·
2025
·
IF 2.8
Yanlin Jiang,Yang Gao,Hangqing Xue,Yeqiang Lu,Lixin Xue
Polyamide (PA) based thin-film nanocomposite (TFN) membranes containing zeolitic imidazolate framework (ZIF) particles, denoted as PA (ZIF)-TFN membranes, were fabricated via interfacial polymerization (IP) between m-phenylenediamine (MPD) and 1,3,5-benzenetricarbonyl chloride (TMC). ZIF-8 particles were incorporated by direct dispersion into the oil-phase solution. Subsequently, the membranes were etched with xylenol orange disodium salt (XO) under acidic conditions to produce reverse osmosis (RO) membranes with improved water flux and salt rejection. These improvements were attributed to additional water-permeation channels and the sealing of non-selective interface defects. Solution pH, etching duration, and XO concentration also play roles in the structure and performance of the optimized RO membranes. After 12 h of etching, superior TFN/XO (12) RO membranes were obtained with rejection rate increased from (99.0% ± 0.2%) to (99.7% ± 0.1%), and water flux increased from (42.3 ± 0.9 L·m −2 ·h −1 ) to (65.1 ± 0.9 L·m −2 ·h −1 ). In addition, the membranes exhibited excellent boron removal rate, operational stability, and anti-pollution performance under conditions of 32,000 ppm NaCl and 55 bar.
研究领域:
膜科学
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材料工程
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化学工程
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纳米技术
·
水处理
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产品关联
DOI
高影响因子
Polymers
·
2022
·Vol. 14
·期 9
·1656
·
IF 4.967
Yang Xue,Wuxinchen Yang,Renliang Yue,Yunfa Chen
The decontamination of radioactive materials on the surfaces of nuclear facilities has generated large quantities of waste from the rapid development of the nuclear industry, posing a potential threat globally. Strippable coating has been employed for some time to remove radioactive contamination due to its high performance and removability, flexibility, and compatibility with various substrates. Herein, an aqueous strippable coating based on an adsorbent/polyvinyl alcohol (PVA) polymer was developed to remove radioactive uranium from stainless-steel surfaces that showed greater decontamination than that of DeconGel, with an efficiency of 87.2% for 5 g/L uranium and 95.5% for 22.5 g/L uranium, along with a high repeatability and better mechanical properties. Furthermore, the prepared coating was versatile and could be applied to a range of substrate surfaces (lacquered, aluminum, glass, plastic, and ceramic), with outstanding performance ranging from 79.2 to 95.4% for 1 g/L uranium. The prepared coating could also be applied through brushing or spraying to horizontal or vertical substrates. The exceptional performance could be due to the synergistic effect of the introduction of ethylene diamine tetra-acetic acid disodium salt (EDTA-2Na) as a chelating agent and the nano-adsorbent CaCO3/TiO2.Keywords:strippable coating;surface radioactive uranium;primary decontamination efficiency;versatility;repeatability and mechanical properties
研究领域:
核工程
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材料科学
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环境科学
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产品关联
DOI
PubMed
高影响因子
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY
·
2021
·
IF 4.291
Junjie Li,Yuanyuan Peng,Jhair Peña,Jinfeng Xing
Nanogels based Polyethylene glycol diacrylate (PEGDA) attracted much attention due to their promising application in drug delivery and tissue engineering. Here, PEGDA photopolymerization at 532 nm with different initiating systems was investigated. Nanogels can be obtained using single 2′,4′,5′,7′-tetrabromofluorescein disodium salt (EY) as the photoinitiator. To increase the polymerization rate, EY, triethanolamine (TEOA), and diphenyl iodonium hexafluorophosphate (DPI) were investigated as a three-component initiating system. With that initiating system, the conversion of PEGDA double bond was higher than 90 % in 1 min at extremely low irradiation energy density (P= 0.95 mW/cm 2 ). However, the conversion of PEGDA double bond was only 51.5 % in 1 min at the same irradiation energy density when using EY and TEOA as two-component initiating system. Subsequently, the corresponding mechanism of the three-component (EY-TEOA-DPI) initiating system was illustrated. DPI might participate in two ways of photooxidation and reduction, which dramatically improved the polymerization rate. The EY-TEOA-DPI initiating system is promising to be applied in the preparation of multifunctional hydrogels.
研究领域:
材料科学
·
高分子化学
·
生物医学工程
·
药学
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产品关联
DOI
高影响因子
JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2024
·
IF 9.4
Yangyang Chen,Xin Wang,Boyan Liu,Yingjuan Zhang,Yiping Zhao,Songcan Wang
It has been widely accepted that the generation of reactive oxygen species such as superoxide radical, hydroxyl radical, and hydrogen peroxide during photocatalysis is responsible for the degradation of azo dyes. However, it is unclear which reactive oxygen species primarily contributes to the degradation efficiency of azo dyes. Here, we demonstrate that the directional regulation of reactive oxygen species in titanium dioxide (TiO 2 ) to form superoxide radicals by ethylenediaminetetraacetic acid disodium salt (EDTA-2Na) can significantly improve the degradation performance of methyl orange. The optimized addition of EDTA-2Na can completely degrade azo dyes such as methyl orange, acid orange and alkaline orange at a concentration of 10 mg/L in about 20 min, which is not only higher than that achieved by pristine TiO 2 under Xe lamp light but also far superior to the reported degradation efficiency of modified TiO 2 . Even under natural sunlight, this strategy can also effectively decompose azo dyes, demonstrating the great potential for practical water treatment using low-cost TiO 2 photocatalysts.
研究领域:
环境科学
·
材料科学
·
化学工程
·
光催化
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产品关联
DOI
PubMed
高影响因子
RSC Advances
·
2016
·Vol. 6
·期 92
·89484-89491
·
IF 3.289
Yingshuai Liu,Jin Xie,Zeying Zhang,Zhisong Lu
O-GlcNAcylation is a very important post-translational modification of nucleocytoplasmic proteins. Aberrant O-GlcNacylation has been found in a variety of human diseases including many types of cancers, diabetes, and Alzheimer's disease. However, analysis of protein O-GlcNacylation still remains a great challenge due to its low levels and labile nature. Herein, a highly sensitive and reliable colorimetric method is developed by use of wheat germ agglutinin (WGA) lectin for specific recognition of O-GlcNAc and gold nanoparticle (AuNP)-catalyzed copper deposition for signal amplification. In presence of the target molecule, AuNP is specifically introduced onto the sensing surface and then catalyzes the copper deposition. An Au@Cu core–shell structure is produced from the deposition. The obtained copper shell on AuNP is dissolved by FeCl3 due to the oxidation–reduction reaction between copper and Fe3+, resulting in Cu2+ and Fe2+, which subsequently form a red coordination complex in the presence of bathophenanthrolinedisulfonic acid disodium salt (BPT2−). Thus, the amount of the red complex is proportional to the level of O-GlcNAc. Qualitative O-GlcNAc detection is realized by direct readout with the naked eye, while the quantitative analysis is achieved by measurement of the absorbance using a UV-Vis spectrophotometer. With increasing time, more and more copper is deposited on the surface of AuNP, thus achieving significant signal amplification. Under optimal conditions, an ultralow limit of detection (LOD) down to 0.02 pg mL−1 is achieved with GlcNAc-conjugated BSA as a model analyte. The developed platform was also successfully applied to analyze O-GlcNAcylation levels in prostate cancer cell line PC-3 and normal cell line RWPE-1. The results obtained by the proposed method are in good agreement with the data from protein microarray assays, demonstrating its great potential for sensitive and reliable O-GlcNAcaylation detection in fundamental research and in cancer diagnosis.
研究领域:
生物化学
·
分析化学
·
癌症生物学
·
蛋白质科学
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产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）