JOURNAL OF THE CHINESE CHEMICAL SOCIETY
·
2017
·Vol. 64
·期 2
·231-238
·
IF 0.935
Jie Wu,Zongmei Wu,Xuejiao Sun,Shichao Yuan,Ruling Zhang,Qingliang Lu,Yueqin Yu
Sodium alginate (SA) was combined with poly( N -isopropylacrylamide) (PNIPAAm) to prepare thermosensitive hydrogels through semi-interpenetrating polymer network (semi-IPN) and fully interpenetrating polymer network (full-IPN). The thermosensitive, swelling, mechanical, and thermal properties of pure PNIPAAm, SA/PNIPAAm semi-IPN, and Ca-alginate/PNIPAAm full-IPN hydrogels were investigated. The formation of semi-IPN and full-IPN significantly improved the hydrogels’ swelling capability and mechanical properties without altering their thermosensitivity. 5-Fluorouracil (5-Fu) was selected as a model drug to study the release behaviors of the hydrogels. It was found that in vitro controlled drug release from semi-IPN hydrogels showed an initial release burst, followed by a slower and sustained release, before reaching equilibrium. Full-IPN hydrogels showed slow and sustained release during the whole process. Temperature and pH were found to affect the rate of drug release. Ca-alginate/PNIPAAm full-IPN hydrogels have potential application as drug delivery matrices in controlled drug release.
研究领域:
生物材料
·
药剂学
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高分子科学
·
组织工程
·
药物递送系统
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DOI
高影响因子
JOURNAL OF APPLIED POLYMER SCIENCE
·
2014
·Vol. 132
·期 9
·
IF 1.64
Yan-Yan Hu,Jing Zhang,Qi-Chen Fang,Dong-Mei Jiang,Chu-Cheng Lin,Yi Zeng,Ji-Sen Jiang
A novel semi-interpenetrating poly(2-hydroxyethyl methacrylate) (pHEMA) based polyelectrolyte hydrogel [p(HEMA- co -METAC)/PEG] was prepared by copolymerizing HEMA with the cationic monomer 2-methacryloyloxyethyltrimethyl ammonium chloride (METAC) in the presence of polyethylene glycol (PEG) with different content and molecular weight (MW 4000 and 400). The chemical structure of the gels was confirmed by FT-IR spectroscopy, morphology study was performed by scanning electron microscope (SEM), thermal stability was revealed by thermogravimetric analysis (TGA), and the mechanical properties were determined by electronic universal testing machine. Swelling studies showed introduction of cationic monomer METAC led to high water content, and the obvious salt and pH sensitive properties were observed which proved the smart behavior of the semi-interpenetrating polymer networks (IPNs) gels. In addition, the effect of temperature and some important biological solution on swelling behavior were reported. Cytotoxicity test demonstrated that synthesized gels owned satisfactory cytocompatibility and were convenient for the application as biomaterials. Finally, the weak bovine serum albumin (BSA) adsorption on semi-IPNs by introducing METAC and controlling the content of PEG in gels demonstrated that they were of good protein resistance effect in biomedical applications. © 2014 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2015 , 132 , 41537.
研究领域:
材料科学
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生物医学工程
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产品关联
DOI
高影响因子
CONSTRUCTION AND BUILDING MATERIALS
·
2024
·
IF 7.4
Jie Pan,Xueliang Chen,Yizhen Chen,Wendi Liu,Mingen Fei,Renhui Qiu
An adhesive serves as a vital tool in construction, repair, and rehabilitation projects. Typically crafted from polymer materials such as epoxies or polyurethane latex, it facilitates the creation of resilient bonds between a variety of surfaces, ranging from concrete-concrete and metal-concrete to concrete-composites. However, employing epoxy or polyurethane individually as adhesives often demonstrate insufficient performance and weak interfacial adhesion during service. In this study, an adhesive combining polyurethane and epoxy was synthesized, featuring an interpenetrating polymer network (IPN) structure. This innovative agent was created using polyols sourced from soybean oil and a commercial epoxy resin. By tuning the infusion of polyurethane content, the resultant resin exhibited favorable flowability in civil applications, simultaneously improved strength and toughness due to the IPN structure, and outstanding thermal stability. Notably, the incorporation of 20 wt% polyurethane yielded a polymer with a remarkable tensile strength of 35.9 MPa. Additionally, the bonding adhesion of the prepared resins on concrete specimens was investigated through splitting tensile test and shear strength test. The study explored the influences of polyurethane content, concrete strength, and adhesive layer thickness on interfacial bonding strength. The introduction of an IPN structure within the PU-20 agent proved advantageous for enhancing the bonding adhesion of the concrete, resulting in remarkable interfacial tensile and shear strengths of 4.56 MPa and 21.73 MPa, respectively.
研究领域:
材料科学
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土木工程
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高分子化学
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建筑材料
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产品关联
DOI
高影响因子
JOURNAL OF SOL-GEL SCIENCE AND TECHNOLOGY
·
2014
·Vol. 71
·期 2
·246-253
·
IF 1.547
Liu Jian-Guo,Xu Liang,Fang Yong-Qin
Novel hybrid organic–inorganic coatings with interpenetrating network were synthesized by the acid-catalyzed hydrolytic co-polycondensation of tetraethoxysilane and 3-metacryloxypropyltrimethoxysilane, followed by radical polymerization with methyl methacrylate and triallyl isocyanurate (TAIC). The hybrid coatings were characterized by Fourier transformed infrared spectroscopy, thermogravimetric analysis and scanning electron microscope, and their anti-corrosion behaviors were evaluated by potentiodynamic polarization, electrochemical impedance spectroscopy and salt spray test. The results indicated that the hybrid coatings exhibited excellent anti-corrosion ability by forming a physical barrier between metal and its external environment. Thermal stability of the hybrid coatings was increased after the addition of TAIC. Furthermore, hydrophobic properties of the hybrid coatings were examined by measuring the contact angles, and the change in wetting characteristics of the hybrid coatings was not obvious.
研究领域:
材料科学
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表面工程
·
腐蚀防护
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DOI
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2024
·
IF 7.7
Wenjing Zhang,Yin Zeng,Fengying Cai,Hongliang Wei,Yuxuan Wu,Hui Yu
Hydrogels based on biopolymers have attracted considerable interest in the last decades. Herein, an interpenetrating network hydrogel (IPN-Gel) adsorbent from starch-chitosan was fabricated facilely in one-pot through tandem Schiff base reaction and photopolymerization. First, aldehyde starch (DAS) was synthesized by the reaction of soluble starch with sodium periodate. Afterward, acrylamide (AM), 2-acrylamido-2-methylpropanesulfonic acid (AMPS), polyethylene glycol dimethacrylate (PEGDMA), photoinitiator, chitosan and DAS were dissolved in water to obtain a clear solution. Schiff base reaction between chitosan and DAS took place quickly to form the first network, and then photopolymerization of AM, AMPS, and PEGDMA occurred under ultraviolet radiation to form the second network. The preparation conditions of the as-prepared IPN-Gel were optimized with two indexes of gel mass fraction and swelling ratio. Its swelling behavior with pH and temperature change was explored. Finally, its adsorption performance was characterized with methylene blue (MB) as a model contaminant. The maximum adsorption capacity of IPN-Gel can reach 2039 mg·g −1 at pH =10. Its adsorption performance accords with Langmuir isothermal model and pseudo-second-order kinetic model and it was mainly controlled by chemisorption. This strategy is expected to found broad application prospects in the preparation of hydrogel adsorbents.
研究领域:
材料科学
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环境科学
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产品关联
DOI
PubMed
高影响因子
ZEITSCHRIFT FUR NATURFORSCHUNG SECTION B-A JOURNAL OF CHEMICAL SCIENCES
·
2020
·Vol. 75
·期 8
·733-737
·
IF 0.839
Gao-Feng Wang,Shu-Wen Sun,Hong Sun,Bo-Hui Wei,Yan-Fei Zhao,Li-Xin Meng
A three-dimensional (3D) two-fold interpenetrated coordination polymer, {[Cd(bipmo)(bpda)]·1.25(H 2 O)} n ( 1 ), (bipmo = bis(4-(1H-imidazol-1-yl)phenyl)methanone, H 2 bpda = 1,1ʹ-biphenyl-2,2ʹ-dicarboxylic acid), was synthesized by a solvothermal method. It has been characterized by elemental analyses, infrared (IR) spectroscopy, and single-crystal X-ray diffraction. The topological structure of 1 consists of uninodal dia nets with two-fold penetration. The thermal stability and the luminescence properties of complex 1 were investigated.
研究领域:
化学
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材料科学
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DOI
高影响因子
NEW JOURNAL OF CHEMISTRY
·
2020
·Vol. 44
·期 37
·16045-16053
·
IF 3.288
Yang Ma,Mingming Li,Keren Shi,Zhifeng Chen,Baozhong Yang,Deyu Rao,Xiawei Li,Wei Ma,Shaozhang Hou,Guojing Gou,Huiqin Yao
Based on semi-interpenetrating polymer network (semi-IPN) hydrogel films, a multiple stimuli-responsive film system composed of poly(acrylic acid) (PAA) and N,N-diethyl acrylamide (DEA), designated as PAA–PDEA semi-IPN films, was realized on a glassy carbon (GC) electrode surface with a one-step polymerization method. Rutin (RT), an electroactive probe, displayed invertible pH-, thermo- and SO42− concentration–sensitive cyclic voltammogram (CV) behaviors in the film system. This multiply sensitive electrocatalysis of RT at the PAA–PDEA films was employed to further investigate the multiple stimuli-responsive ON–OFF behaviors of RT. The scanning electron microscopy (SEM) images and control experiments showed pH-sensitive ON–OFF properties of RT, which could be ascribed to the protonated/deprotonated carboxylic (–COOH) groups of the PAA component in different pH buffers and the properties of RT itself. However, the confirmation change or phase transition of the PDEA hydrogel film between the coil and globular states led to thermo- and SO42− concentration–sensitive ON–OFF properties. According to these results, a 3-input/3-output logic gate and a 2-to-1 encoder were constructed successfully. This present system was fabricated for the first time, which may offer numerous possibilities for the design of new electrochemical drug sensors, drug-mimicking release processes and other medical applications. Furthermore, it also can contribute to the development of biomolecular or molecular computing.
研究领域:
材料科学
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生物医学工程
·
电化学
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DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2025
·
IF 13.2
Handong Shi,Shijiao Li,Kai Han,Chuanhao Xu,Lei Gao,Fan Liao,Yanpeng Lv,Yurong Zhang,Chongwei An
This study presents a strategy for developing CL-20 (Hexanitrohexaazaisowurtzita-ne)-based energetic composites with enhanced mechanical properties and intrinsic safety through the synergistic design of PVA (polyvinyl alcohol) /PAA (polyacrylic acid) interpenetrating polymer networks (IPNs) and direct ink writing (DIW) technology. Based on the “hydrogen bond-covalent bond-plasticization” synergistic reinforcement strategy, an IPNs gel system with tunable mechanical properties was developed. After optimizing the polymer ratio (4:3), Crosslinking agent (1 %), and glycerol content (17.5 %), a balance between toughness, ductility, and strength was attained. The DIW-printed structure exhibited excellent molding accuracy and interfacial adhesion (0.924 MPa to aluminum). System characterization demonstrated that the IPN structure achieved uniform CL-20 distribution and controlled porosity, significantly enhancing its mechanical properties, safety, and detonation performance. Its elastic modulus is close to that of engineering plastics(4.504 GPa), the hardness is between soft rubber and hard plastics (0.107 GPa), and the compressive strength is higher than that of typical PBX explosives (15.64 MPa). By using PVA/PAA IPNs, a “topological entanglement-passivation defect” mechanism was established to suppress mechanical sensitivity. Compared to submicron ε-CL-20, the molded sample reduced impact sensitivity by 33.3 % and friction sensitivity by 128.6 %. Additionally, detonation propagation was achieved in a 1.2 × 1.2 mm charge slot within a 90°-160° corner range, with the critical detonation transmission size reaching 0.3 × 0.3 mm and the detonation velocity maintained at 7362 m/s (82.4 % theoretical detonation velocity). This study offers a scalable manufacturing framework for developing energetic devices that combine mechanical properties, intrinsic safety, and adaptability to complex structures.
研究领域:
材料科学
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爆炸化学
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先进制造
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产品关联
DOI
高影响因子
RSC Advances
·
2016
·Vol. 6
·期 28
·23233-23241
·
IF 3.289
Jun Wan,Tao Tao,Yong Zhang,Xiangmin Liang,Aijiao Zhou,Chang Zhu
Adsorption has attracted much attention for its effectiveness, low cost and the possibility of regeneration among many phosphorus removal methods. In this study, a novel interpenetrating network (IPN) structural hydrogel based on N-isopropylacrylamide and aluminum alginate was synthesized and applied for phosphate adsorption. SEM, FTIR and XPS were applied to characterize the poly N-isopropylacrylamide/aluminum alginate (PNIPAM/AA) IPN hydrogel beads before and after adsorption. It was found that the maximum adsorption capacity was reached at pH = 3, adsorption capacity decreased with adsorbent dosage increasing, and SO42− had much more negative effects on phosphate adsorption compared with Cl− and NO3−. A pseudo-second-order kinetic model and intra-particle kinetic model fitted well with the experimental data, indicating chemical adsorption and intra-particle diffusion was the rate-controlling step of phosphate adsorption. Moreover, equilibrium isotherm experimental data were well described by the Freundlich and Slips model, suggesting heterogeneous multilayer adsorption was dominant during adsorption process. The regeneration study indicated that the adsorption capacity of adsorbent remained at a relatively high level after five times of regeneration. Column adsorption and regeneration results showed PNIPAM/AA hydrogels had strong phosphate adsorption capacity and had potential in large scale application. Hence, PNIPAM/AA hydrogel beads could be a promising adsorbent for phosphate recycle in the future.
研究领域:
环境科学
·
材料科学
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产品关联
DOI
高影响因子
MATERIALS & DESIGN
·
2024
·
IF 7.6
Maojian Li,Yimeng Zhang,Yanan Liu,Guixue Chen,Nanxi Zhao,Chang Liu,Xiang Li,Manli Wang,Jian Song,Zheng Luo
The application of pressure-sensitive adhesives (PSAs) in transdermal drug delivery systems (TDDSs) is limited. Insufficient cohesion in TDDS can lead to cold flow, patch displacement, dose inaccuracies, and the ‘dark ring’ phenomenon. To address these issues, we developed a semi-interpenetrating network (semi-IPN) PSA using a 2-hydroxyethylacrylate-modified acrylic copolymer as the linear polymer and poly[tri(propylene glycol) diacrylate] as the cross-linked network. Semi-IPN PSAs have better mechanical properties compared to traditional PSAs. The cohesion of the semi-IPN PSA was 31 times and 1.6 times that of commercially available DURO-TAK®87-2287 and DURO-TAK® 87–4098, respectively, and the cold flow of the semi-IPN PSA was significantly reduced. Furthermore, the semi-IPN PSA adhered to the human forearm for longer time and did not exhibit the ‘dark ring’ phenomenon after removal. When loaded with flurbiprofen, the semi-IPN PSA was found to maintain high levels of drug release and skin permeation amount, and flurbiprofen loading did not affect its superior cohesive performance. In conclusion, the innovative application of the semi-IPN PSA for TDDS showed excellent mechanical properties, effective adhesion to the skin without irritation, and highly effective drug release. These findings indicate that the use of the semi-IPN is both simple and highly effective for TDDS.
研究领域:
药剂学
·
材料科学
·
生物医学工程
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产品关联
DOI
高影响因子
CELLULOSE
·
2018
·Vol. 26
·期 3
·1825-1839
·
IF 3.809
Lin Fengcai,Lu Xiangchao,Wang Zi,Lu Qilin,Lin Guanfeng,Huang Biao,Lu Beili
Cellulose hydrogels usually have poor mechanical properties which seriously limit their applications in biomedical or industrial fields. Herein, an interpenetrating polymer network strategy was proposed to construct double network hydrogels composed of cellulose and polyacrylamide with high mechanical strength and pH responsive properties. The synergistic interactions and strong hydrogen bonds between two networks contributed to the dissipation of mechanical energy, as evidenced by the compressive stress–strain and rheology analyses. The compressive strength and compressive modulus for cellulose–polyacrylamide interpenetrating network (C–PAM IPN) hydrogels could reach up to 5.62 and 22.47 MPa, which is nearly 18 and 23 times higher than that of cellulose hydrogels. Moreover, these tough C–PAM IPN hydrogels exhibit pH sensitive properties in various pH solutions. Therefore, this paper provides a general strategy to enhance the mechanical and physical properties of cellulose-based hydrogels, which are potentially useful in developing novel cellulose-based hydrogels and expanding their applications.
研究领域:
材料科学
·
生物医学工程
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产品关联
DOI
高影响因子
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
·
2024
·
IF 4.9
Yuxuan Zhang,Zaosheng Lv,Guangli Chen,Yuhang Liu,Yang Lei,Yanfen Huang
Hydrogel, a common hydrophilic material, is often used in wastewater treatment. In order to expand the application of hydrogel in superhydrophilic coatings, we chose acrylic acid (AA) and methacryloyloyloxy ethyltrimethylammonium chloride (DMC), two chemical materials commonly used in wastewater treatment, and semi-interpenetrating networks (semi-IPN) based on the metal mesh structure were successfully polymerization, and a superhydrophilic membrane (PAA/PDMC@SSM(stainless steel mesh)) was prepared. The membrane ensures the efficient separation of different types of oil-water mixtures under high flux conditions (up to 99 % separation efficiency) and the effective removal of oil from water-in-oil emulsions. This green polymer material can be used for efficient oil-water separation as well as separation of water-in-oil emulsions (separation efficiency close to 98 %). In order to prevent microorganisms from clogging the separation membrane during wastewater treatment, it was tested for E. coli with 99 % inhibition. PAA/PDMC@SSM was found to be acid-resistant, durable and self-cleaning for viscous oils.
研究领域:
材料科学
·
环境工程
·
高分子化学
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）