Analytical Methods
·
2020
·Vol. 12
·期 37
·4551-4555
·
IF 2.596
Haijian Liu,Miao Wang,Zhenxiang Li,Chengjie Xin,Guofu Huang
Due to the inner filter effect (IFE) between Brilliant Blue (BB) and gold nanoclusters (AuNCs), a simple and rapid approach for BB detection was developed. Since the absorption spectrum of BB has a good overlap with the emission spectrum of the AuNCs, the fluorescence of the AuNC solution was quenched after adding BB. Under optimal conditions, a good linear relationship for detection of BB was obtained from 0.05 to 7.5 μM, and the detection limit was 0.0167 μM. More importantly, the assay was successfully applied to assess BB in food samples such as hard candy, chocolate and dried blueberries, showing its potential in food quality control in the future.
研究领域:
分析化学
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食品安全
·
纳米技术
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
·
2020
·
IF 4.192
Han Zhang,Lulu Wang,Xiaolin Yao,Zonghan Wang,Leina Dou,Lihong Su,Man Zhao,Jing Sun,Daohong Zhang,Jianlong Wang
An innovative lateral flow competition immunoassay (LFCIA) for detecting clenbuterol (CL) was developed by employing the advantages of the coomassie brilliant blue (CBB) staining method. An antibody stained by CBB was used both as a recognition reagent and as a chromogenic probe, enabling the simple but sensitive LFCIA of CL. The CBB-based LFCIA exhibited sensitivity for CL with a detection limit of 2 ng mL–1. Furthermore, this strategy was preliminarily verified by screening for CL in milk, pork tenderloin, and swine liver with recoveries ranging from 81 to 102%. Compared with conventional LFCIAs, the use of CBB as a signal label not only avoided the complicated material synthesis and surface modification process but also simplified the cross-linking with antibodies, meanwhile reducing the steric hindrance and increasing the possibility of immune recognition reactions, which was propitious for the effective utilization of antibodies. Taking advantages of the simplicity, rapidity, and cost-effectiveness, the CBB-based LFCIA may have potential for on-demand monitoring of general harmful small molecules by changing the kind of the staining antibody.
研究领域:
分析化学
·
食品安全
·
生物技术
✓ 已验证
DOI
PubMed
高影响因子
MICROCHEMICAL JOURNAL
·
2025
·
IF 5.1
Zhihao Fang,Wenxu Wang,Mengjie Bai,Yongwei Li,Yiqing Jiao,Yue Zhou,Kaiyue Ma,Shutong Zhao,Xiaoran Wang,Bing Liu,Haijian Liu
Brilliant blue (BB), a synthetic dye commonly used as a food coloring agent and in pharmaceutical formulations, poses significant health risks when consumed excessively. Prolonged or high intake of BB has been linked to potential toxicity, including disruptions in metabolic pathways and adverse effects on organ function, particularly the liver. In this study, a stable dual-emission sensor, consisting of carbon dots and copper nanoclusters, was designed for the highly selective detection of BB, utilizing the inner filter effect. When excited at 380 nm, this sensor displays distinct emission peaks at 430 nm and 640 nm. Upon addition of BB, the emission at 640 nm is significantly quenched, and the fluorescence intensity ratio (F 640 /F 430 ) displays a linear relationship with BB concentrations ranging from 1 to 1000 nmol/L, with a detection limit of 1 nmol/L. The probe was successfully applied for detecting BB in real samples, with recoveries ranging from 94.8 % to 108.8 % and a relative standard deviation of less than 2.2 %.
研究领域:
分析化学
·
纳米技术
·
食品科学
·
环境科学
·
生物化学
✓ 已验证
产品关联
DOI
高影响因子
Chemosensors
·
2020
·Vol. 8
·期 3
·70
·
IF 3.108
Zirong Qin,Jinyan Zhang,Ying Liu,Jingtao Wu,Guangli Li,Jun Liu,Quanguo He
In this work, we report a simple but efficient voltammetric sensor for simultaneous detection of ponceau 4R and tartrazine based on TiO2/electro-reduced graphene oxide nanocomposites (TiO2/ErGO). TiO2/ErGO nanocomposites were prepared by ultrasonically dispersing TiO2nanoparticles (TiO2NPs) into graphene oxide (GO) solution followed by a green in-situ electrochemical reduction. TiO2NPs were uniformly supported on ErGO nanoflakes, which provides a favorable interface for the adsorption and subsequent oxidation of target analytes. TiO2/ErGO showed remarkable electrocatalytic capacity for the oxidation of ponceau 4R and tartrazine, with minimized oxidation overpotentials and boosted adsorptive striping differential pulse voltammetric (AdSDPV) response peak currents. Under the optimal experimental conditions, the anodic peak currents of ponceau 4R and tartrazine increase linearly with the respective natural logarithm of concentrations from 0.01 to 5.0 μM. The detection limits (LOD = 3σ/s) for ponceau 4R and tartrazine are 4.0 and 6.0 nM, respectively. The extraordinary analytical properties of TiO2/ErGO/GCE are primarily attributed to the synergistic enhancement effect from ErGO nanoflakes and TiO2NPs. Moreover, the proposed TiO2/ErGO/GCE achieves reliable determination of ponceau 4R and tartrazine in orange juice with excellent selectively, reproducibility and stability. Together with simplicity, rapidness, and low cost, the proposed sensor demonstrates great potential for on-site detection of azo colorants.Keywords:ponceau 4R;tartrazine;TiO2;electro-reduced graphene oxide;voltammetric sensor
研究领域:
分析化学
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食品科学
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材料科学
✓ 已验证
产品关联
DOI
高影响因子
ANALYTICAL SCIENCES
·
2019
·Vol. 35
·期 6
·639-644
·
IF 1.618
Shan Xueling,Pan Yuting,Chen Xiaohui,Wang Wenchang,Chen Zhidong
A novel electrochemiluminescence (ECL) sensor for detection of brilliant blue FCF (BB) has been developed using Ru@ Zn-MOF/nafion modified GCE (glass carbon electrode) in this research. Different from conventional method for usage of Ru(bpy) 3 2+ in solution-phase, Ru(bpy) 3 2+ here was immobilized on a zinc-metal-organic-framework (Zn-MOF). After adding BB, a significant quenching phenomenon of ECL intensity was observed. The behavior of BB on the quenching effect of Ru(bpy) 3 2+ /Zn-MOF in different conditions was investigated thoroughly and the detection limit was achieved to 2.5 × 10 −8 M in an optimized condition. Furthermore, the interference of some conventional ions and amino acids to the detection of BB was also investigated. Additionally, the composite showed a good effect on the detection of BB in commercial samples. The proposed sensor provided a promising platform for food safety analysis, environmental monitoring and clinical testing.
研究领域:
分析化学
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食品安全
·
环境监测
✓ 已验证
产品关联
DOI
PubMed
高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
·
2022
·
IF 9.136
Wenting Zhu,Wenting Li,Zhongtian Li,Yanhui Lu,Jieping Fan,Hua Xiong,Hailong Peng
In this study, magnetic porous carbon microsphere composed of molecularly imprinted nanofibers (MPCM@MINs) were constructed and used as an adsorbent for the highly efficient extraction of Brilliant Blue (BB) in food samples. The MPCM@MINs contained imprinted nanofibers and a three-dimensional hierarchical porous structure with a magnetic responsive ability, resulting in a high surface area (368.3 m 2 ·g −1 ), low mass-transfer resistance, large adsorption capacity, and fast separation ability. The maximum adsorption capacity of MPCM@MINs for BB was 39.47 mg·g −1 with excellent selectivity and a high imprinting factor (6.12). Moreover, MPCM@MINs exhibited good anti-interference ability, reusability and reliability. Importantly, BB can be easily and rapidly detected in food samples using MPCM@MINs as an adsorbent followed with UV–Vis method, and the relative standard deviation was lower than 5.85%. Therefore, MPCM@MINs may be a promising adsorbent for pollutant extraction in food samples due to the combination of different strategies of nanofibrous imprinting, magnetic separation, and hierarchical porous structure.
研究领域:
材料科学
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环境科学
·
分析化学
✓ 已验证
DOI
高影响因子
Nano Research
·
2023
·Vol. 16
·期 5
·6290-6297
·
IF 9.9
Cai Jiahao,Song Shizheng,Zhu Lijie,Lu Qipeng,Lu Zong,Wei Yanying,Wang Haihui
A kind of two-dimensional (2D) metal-organic framework (MOF) material, Cu-meso-tetrakis (4-carboxyphenyl) porphine (Cu-TCPP) nanosheets with wrinkled and flat morphologies are used as building blocks to assemble membranes by vacuum filtration (VF) and electrophoretic deposition (EPD) as energy-efficient nanofiltration (NF) membranes to remove dyes from water. Since the nanosheets with wrinkled structure can provide additional water transport channels, thereby increasing the water permeance, in the premise of a high rejection (> 97.0%) for the dye brilliant blue G (BBG) (1.60 nm × 1.90 nm), the water permeance of the membrane assembled by the wrinkled nanosheets (∼ 1170 nm) is about 4 times that of the membrane assembled by the flat nanosheets (∼ 530 nm), reaching 16.39 L·m −2 ·h −1 ·bar −1 . Additionally, the use of the relatively flat nanosheets and the membrane preparation method of electrophoretic deposition is more conducive to stack nanosheets orderly and reduce defects. Therefore, the water permeance of the membrane prepared by EPD (∼ 1170 nm) with flat nanosheets is about twice that of the membrane prepared by VF (∼ 530 nm), achieving 9.40 L·m −2 ·h −1 ·bar −1 with similar rejection (> 97.0%) of dye evans blue (EB) (3.10 nm × 1.20 nm). Furthermore, these membranes still exhibit good separation performance at high pressure of 0.6 MPa. Nanosheets with diverse structures and various membrane fabrication processes provide new directions for the separation performance optimization of 2D MOF materials for water purification.
研究领域:
材料科学
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环境工程
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纳米技术
·
水处理
✓ 已验证
产品关联
DOI
高影响因子
ACS Sustainable Chemistry & Engineering
·
2019
·
IF 6.97
Xiangju Song,Yuchao Wang,Canzhu Wang,Minghua Huang,Saeed Gul,Heqing Jiang
Membrane separation is widely regarded as a promising technology for water treatment. To run the membrane at the optimal conditions, preheating of feedwater before being sent into the membrane unit is often employed, which results in high energy consumption. Here we report a multifunctional system that combines traditional pressure-driven membrane filtration with solar thermal technology based on a photothermal membrane for high-efficiency water treatment. The multifunctional membrane consists of multiwalled carbon nanotubes and polysulfone (MWCNT-PSf), which not only facilitates the water permeation through the membrane but also effectively heats the feed solution by sustainable solar energy. The composite membrane containing MWCNT demonstrates excellent light absorption of 94% over the full solar spectrum range, which can effectively preheat the feedwater. With the assistance of light irradiation, the MWCNT-PSf photothermal membrane exhibits high water flux over 314 L m–2 h–1 with a rejection above 95% for coomassie brilliant blue at 0.10 MPa, which is 101.3% higher than that without light irradiation. The solar-intensified ultrafiltration system based on a porous photothermal membrane provides a new avenue to treat wastewater or seawater.
研究领域:
环境工程
·
材料科学
·
水处理
✓ 已验证
产品关联
DOI
高影响因子
ANALYST
·
2025
·
IF 3.3
junbin cao,chengcheng xu,Jianwei Zhao,wenmei tao
This research created a disposable electrochemical sensor utilizing a chitosan-biochar (CS-H500) composite-modified glassy carbon electrode (GCE) for the very sensitive detection of brilliant blue (BB) in food products. The CS-H500 composite dispersion was synthesized using the ultrasonic dispersion method, while quantum chemical simulations clarified the adsorption mechanism of BB molecules on the electrode surface via π-π conjugation and electrostatic interactions. Optimized experimental settings comprised: 16 μL of CS-H500 dispersion modification, 300 seconds of accumulation period, and a pH 7.0 phosphate buffer. The results indicated that chitosan (CS) markedly enhanced the dispersibility of biochar, augmenting the effective surface area of the modified electrode by 2.53 times (0.179 cm2) in comparison to the bare GCE. The sensor demonstrated a linear detection range of 1.0×10-6 to 1.0×10-4 mol/L for BB, with a detection limit of 1.0×10-7 mol/L (S/N=3), acceptable recoveries (91.49%-102.18%), and commendable reproducibility (RSD=8.01%). Interference studies validated significant selectivity against citric acid, glucose, prevalent metal ions, and proficient differentiation from mixed pigments such as sunset yellow (SY) and fluorescein sodium (FS). The analysis of practical beverage samples confirmed its reliability. This disposable electrode design streamlines operations, prevents cross-contamination, and offers an effective option for on-site monitoring of food additives.
研究领域:
电化学
·
食品安全
·
传感技术
·
纳米材料
·
分析化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
FOOD CHEMISTRY
·
2021
·
IF 7.514
Jingke Xu,Leina Dou,Sijie Liu,Lihong Su,Xuechi Yin,Jing Ren,Huilan Hu,Daohong Zhang,Jing Sun,Zhanhui Wang,Jianlong Wang
Furazolidone (FZD) and its metabolite called 3-amino-2-oxazolidinone (AOZ) would induce carcinogenic and mutagenic effects to human. In this work, to develop a novel, stable, and simple point of care testing (POCT) with a potential to social applied for FZD detection, we utilized the aspect of protein staining of coomassie brilliant blue (CBB) to exploit a new CBB-LFIA strategy free of NPs. Only one mixing step is needed during the probe manufacturing process, which requires just 2 h and is a great time saving strategy compared with other methods (requiring 4–33 h for probe preparation). Besides, the cost of CBB-LFIA is 300 times lesser than other LFIA with respect to obtaining the label. The developed CBB-LFIA was successfully applied to detect AOZ with a detection limit of 2 ng mL −1 , without any influence from other potential interfering compounds. The proposed CBB-LFIA exhibited prominent practical application, and possesses considerable utilization potential in the related field.
研究领域:
分析化学
·
即时检测
·
食品安全
✓ 已验证
产品关联
DOI
PubMed
高影响因子
LWT-FOOD SCIENCE AND TECHNOLOGY
·
2024
·
IF 6
Xiuying Liu,Binbin Guan,Min Yang,Xinwen Bai,Wei Zhang,Pingping Wang,Zaixi Shu,Yiwei Tang,Lijie Zhu
In this study, a novel intelligent water-absorbent cellulose pad with a specified area was developed for the visual and non-destructive monitoring of fish freshness. The pad's substrate was composed of wood pulp cellulose (WPC), and the specified area contained a ratiometric mixture of brilliant blue (BRI) and alizarin (Alz)., fixed with Polyvinyl alcohol (PVA). During the freshness monitoring process, the Alz/BRI-PVA WPC pad exhibited a color transition from green to brown, followed by a shift to purple-red, corresponding to the increasing levels of total volatile base nitrogen (TVB-N) and total viable count (TVC). After testing, a BRI/Alz ratio of 1:8 was selected as the optimal ratio. Compared to the volatile gas-based sensing tags, the pad developed in this study demonstrated a high sensitivity of 53.4% by interacting with the sample exudate to produce signal changes. This study demonstrates the feasibility of using the developed dual-functional pad for water absorption and freshness indications.
研究领域:
食品科学
·
材料科学
·
传感器
✓ 已验证
产品关联
DOI
高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
·
2018
·
IF 5.667
Qian Yang,Jinhua Li,Xiaoyan Wang,Hailong Peng,Hua Xiong,Lingxin Chen
Single-component dual-emission nanoparticles were synthesized by chelating the organic ligand 8-hydroxyquinoline (HQ) to the surface of CdTe/ZnS quantum dots, namely CdTe/ZnQ 2 , and were used to construct a novel mesoporous structured molecular imprinting ratiometric fluorescence sensor by facile one-pot sol-gel polymerization for the visual detection of Brilliant Blue. The CdTe/ZnQ 2 had bimodal fluorescence belonging to CdTe and ZnQ 2 segments, respectively; significantly, the emission wavelength of CdTe was optimized to be 630 nm for the largest overlap with the absorption spectrum of Brilliant Blue. Consequently, fluorescence resonance energy transfer (FRET) efficiency was greatly enhanced, resulting in ideal determination. A favorable linearity toward Brilliant Blue was obtained within 0–1.0 μmol·L −1 along with profuse color evolution from orange to yellowish orange to yellowish green to green, and a high detectability of 8.8 nmol·L −1 was offered. Excellent recognition selectivity for Brilliant Blue over possibly coexistent food colorants was demonstrated, with a high imprinting factor of 7.1. Furthermore, endogenous Brilliant Blue was detected ranging from 0.21 to 41.03 mg/kg in six typical food samples with relative standard deviations lower than 3.5%, and the results agreed well with that afforded by conventional methods. Using Brilliant Blue as a model, this dual-emission color-controllable nanoparticle based imprinting ratiometric fluorescence sensor provided promising perspectives for the highly selective and sensitive, rapid, visual detection of colored substances in complicated matrices.
研究领域:
纳米技术
·
分析化学
·
材料科学
·
食品科学
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）