FIBERS AND POLYMERS
·
2021
·Vol. 22
·期 1
·141-148
·
IF 2.153
Jia Weini,Li Shirong,Luo Zhengxin,Yu Hainan,Zhu Wenjun,Mao Qinghui,Zhang Xiaoli,Liang Zhijie,Dong Aixue
Due to the damage of scalp because of chemical dyes, increasing attention had been paid to the ecological dyeing of human hair. To address the need for ecological restoration and dyeing of human hair, herein, a novel approach has been proposed via laccase-mediated in situ oxidation of dihydroxy phenylalanine (dopamine). As laccase can catalyze dopamine oxidation and then polymerization to produce strongly colored polymers, different biological coloration processes of human hair based on this process were investigated: (i) Human hair was treated with laccase alone; (ii) The absorption of human hair with dopamine, followed by further catalysis of air; (iii) The absorption of human hair with dopamine, followed by further catalysis of laccase; (iv) Simultaneous laccase-mediated polymerization and dyeing of human hair; and (v) Polymerization of Dopamine with laccase and then dyeing human hair. The surface properties of dyed hair were evaluated in terms of ultraviolet (UV)-protection, color fastness, Fourier transforming infrared spectrum (FT-IR), optical microscope, and scanning electron microscopy (SEM). The results show that best hair dyeing effect was achieved via simultaneous laccase-mediated polymerization and dyeing. The dyed hair obtained K/S values of 28, light fastness of level 5, and UPF of 100 + . The optical microscope and SEM observations show that the surface of colored hair fibers was covered with thin burrs, which can be attributed to polydopamine attached with physical adhesive force and covalent reaction. FT-IR analysis shows that functional groups were present on the surface of the dyed hair which can be considered as introduction of hydroxyl radical groups. This biological stain technique may be widely used in dyeing of hair with black color.
研究领域:
生物学
·
生物化学
✓ 已验证
DOI
高影响因子
Energy & Environmental Science
·
2013
·Vol. 7
·期 1
·379-386
·
IF 11.653
Wenjing Qian,Fengxia Sun,Yanhui Xu,Lihua Qiu,Changhai Liu,Suidong Wang,Feng Yan
Heteroatom doped porous carbon flakes were prepared via carbonization of Chinese human hair fibers and employed for high-performance supercapacitor electrode materials. The morphology and chemical composition of the resultant carbon materials were characterized by electron microscopy (EM), energy-dispersive X-ray spectroscopy (EDX), and X-ray photoelectron spectroscopy (XPS) measurements. Human hair carbonized at 800 °C exhibited high charge storage capacity with a specific capacitance of 340 F g−1 in 6 M KOH at a current density of 1 A g−1 and good stability over 20 000 cycles. The specific capacitance of 126 F g−1 is also verified in a 1 M LiPF6 ethylene carbonate/diethyl carbonate (EC/DEC) organic electrolyte at a current density of 1 A g−1. The high supercapacitor performance could be due to the micro/mesoporosity combined with high effective surface area and heteroatom doping effects, combining double layer and Faradaic contributions.
研究领域:
材料科学
·
能源存储
·
电化学
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
·
2024
·
IF 3.1
Songze Wang,Xin Zhou,Xin Wang,Shengyu Cheng,Xi-Ling Li,Jun Nan,Jun Zhe Min
Human hair is a non-invasive biological sample that is easy to collect and store and can reflect long-term body health. However, the correlation between DL-amino acids and metabolic diseases in hair samples has not been studied. Therefore, we propose a novel UHPLC-HRMS method for analyzing seven free chiral amino acids (DL-Thr, DL-Glu, DL-Ala, DL-Val, DL-Pro, DL-Leu, and DL-Phe) simultaneously in hair samples by derivatization of chiral probe 4-(N,N-dmethylaminosulfonyl)-2,1,3-benzoxadiazole-trans-2-methyl-L-proline (DBD-M-Pro) labeled with targeted amino functional groups. Gradient elution was carried out using an ACQUITYTM BEH C18 (100×2.1 mm,1.7 μm) column with a mobile phase of 0.15 % formic acid (FA) in 10 mM ammonium acetate (CH 3 -COONH 4 ) and 0.2 % FA in acetonitrile. The labelled DL-amino acid diastereoisomers could be completely separated, with a resolution (Rs) of 1.59–11.44. These amino acids show a strong linear correlation within the range of 3.1–99.2 pmol (R 2 ≥ 0.9990). Intraday and interday precision was 1.87 %–14.87 %. The average recovery was 96.12 %–105.33 %. The limit of detection (LOD) ranged from 0.29 to 2.11 pmol. We then employed the method to determine the concentration of free chiral amino acids in hair samples from 30 healthy volunteers (HVs) and 30 diabetes patients (DPs). Male diabetes patients had significantly higher levels of L-Thr, L-Val, L-Leu ( p < 0.05), and D-Ala ( p < 0.01) in their hair samples than male healthy volunteers and female diabetes patients had significantly higher levels of D-Ala ( p < 0.05) in their hair samples than female healthy volunteers. This is the first study to confirm the feasibility of using free DL-amino acids in human hair as potential biomarkers for diabetes.
研究领域:
分析化学
·
代谢组学
·
临床化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Scientific Reports
·
2022
·Vol. 12
·期 1
·1-10
·
IF 4.996
Chenxi Yang,Jian Wang,Haiou Zhang,Tingting Cao,Hang Zhou,Jiawei Wang,Bo Bai
Frequent oil spill accidents and industrial wastewater discharge has always been one of the most severe worldwide environmental problems. To cope with this problem, many fluorine-containing and high-cost materials with superwettability have been extensively applied for oil–water separation, which hinders its large-scale application. In this work, a novel human hair fiber (HHF)-polymerized octadecylsiloxane (PODS) fiber was fabricated with a facile one-pot dip-coating synthesis approach, inspired by the self-assembly performance and hydrophobicity of OTS modification. The benefits of prominent hydrophobic/lipophilic behavior lie in the low surface energy, and a rough PODS coating was rationally adhered on the surface of HHF. Driven solely by gravity and capillary force, the HHF-PODS showed excellent oil/water separation efficiency (> 99.0%) for a wide range of heavy and light oil/water mixtures. In addition, HHF-PODS demonstrated durability toward different harsh environments like alkaline, acid, and salty solutions.
研究领域:
环境科学
·
材料科学
✓ 已验证
DOI
高影响因子
Journal of Materials Chemistry B
·
2020
·Vol. 8
·期 47
·10854-10866
·
IF 5.344
Cuifu Fang,Zhiwei Zhong,Teng Zhang,Shuang Jia,Xingwei Ding,Weimin Zhou,Xiaolei Wang
Problems such as massive hemorrhage caused by uncontrolled drug dosage are the main significant obstacles in clinical thrombolytic therapy, which are prominently due to the lack of targeting and controlled release ability of efficient thrombolytic drug systems. In recent years, our team demonstrated that the photothermal effect can facilitate the thrombolytic effect of urokinase plasminogen activator (uPA). However, conventional photothermal agents are relatively expensive or contain heavy metals. If drug delivery systems with low toxicity, minimized heavy metal elements and easy accessibility (preferably provided by human self) can be developed, they will be of value in the future related applications. Herein, uPA-loaded human black hair derived nanoparticles with gelatin capsules (uPA@HBHNP@GNCs) were applied for the first time as a thrombolytic system. Upon irradiation by near-infrared I window (NIR-I) laser or II window (NIR-II) laser, the photothermal effect of HBHNP was triggered to promote the melting of the gelatin encapsulated around the outer layer, thereby realizing the targeted release of uPA. The in vitro and in vivo experiments demonstrated that the deep response to NIR (especially II window) of this system exhibited a satisfactory thrombolytic effect with ideal biosafety. Briefly, the proposed hair derived drug delivery system has the characteristics of human source, low cost, minimum heavy metal components, deep response to NIR (II window) laser, and good biocompatibility, which is expected to be expanded to the treatment for some diseases, even in deep tissue areas.
研究领域:
药学
·
生物医学工程
·
治疗学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ACS Sustainable Chemistry & Engineering
·
2023
·
IF 8.4
Junlei Wang,Zhimin Zhao,Hanmeng Yuan,Hongshuai Gao,Yi Nie
Keratin, a naturally occurring biomaterial, has gained substantial recognition for its application in various domains. Given its abundant presence in human hair, the pursuit of efficient methods for dissolving and extracting keratin is motivated by the dual objectives of maximizing the utility of human hair and promoting ecological sustainability. In this work, a series of deep eutectic solvents (DES) were designed for extraction of keratin from human hair under mild experimental conditions. The effects of DES structure, molar ratios of HBA to HBD, dissolution temperature, and time on the dissolving ability of DES for human hair were investigated in depth. The results showed that ChCl/MEA can effectively dissolve human hair under mild conditions (80 °C, 4 h) with a solubility of 84% and a mass percentage of 20%. FT-IR, XRD, SDS-PAGE, and TGA results showed that the structure of the regenerated keratin was slightly destroyed but still exhibited stable thermal property. Analysis of the reduced density gradient (RDG) and surface electrostatic potential (ESP) verified that the hydrogen bond driven by electrostatic attraction is formed in DESs. Independent gradient model (IGMH) analysis confirmed that the weak interaction between human hair and DES is mainly caused by van der Waals interactions. Additionally, ChCl/MEA displayed an excellent performance in extracting keratin from human hair even after recycling for three cycles.
研究领域:
材料科学
·
化学工程
·
生物技术
·
可持续化学
✓ 已验证
产品关联
DOI
高影响因子
Analytical Methods
·
2023
·Vol. 15
·期 7
·884-895
·
IF 3.1
Xin Wang,Xiaoqi Sun,Yueying Jin,Shengyu Cheng,Yu Han,Minghui Zhang,Lingli Zhang,Xi-Ling Li,Chun-Yan Xu,Jun Zhe Min
This study reports a novel fluorescent chiral derivatization reagent, 4-(N,N-dmethylaminosulfonyl)-2,1,3-benzoxadiazole-(2-succinimidoxy)-trans-2-methyl-L-proline (DBD-S-M-Pro), with a benzoxadiazole structure containing an N-hydroxysuccinimide activation group. DBD-S-M-Pro targets chiral amino-functional compounds under alkaline conditions without a condensation agent. Gradient elution was performed on a BEH C18 (100 × 2.1 mm, 1.7 μm) column with a mobile phase of 0.05% formic acid (FA) in 10 mM ammonium acetate (CH3COONH4) and 0.1% FA in acetonitrile or methanol. The efficiency of the chiral resolution was evaluated under excitation and emission wavelengths of 450 nm and 560 nm, respectively. The 19 chiral amino acids were separated in the range of 1.45–14.84. The resolutions of almost all DL-amino acids exceeded 1.5; the exceptions were serine (Ser) and lysine (Lys), with resolutions of 1.45 and 1.46, respectively. In addition, a new approach was devised for the simultaneous analysis of four chiral amino acids (DL-Glu, DL-Ala, DL-Val, and DL-Phe) in human hair. These amino acids were analyzed in the range of 12.5–400 pmol, with R2 ≥ 0.9990, limits of detection (S/N = 3) of 4–10 pmol, and intraday and interday precisions of 0.57–6.23%. The average spikes in the hair recoveries were 89.76–111.54%, and the matrix effects were 92.47–102.40%. Next, the contents of free chiral amino acids in the hair samples of 10 healthy volunteers (five males and five females) were analyzed with this method, and the differences were compared. The developed DBD-S-M-Pro provides a novel strategy for the sensitive determination of free chiral amino acids in living organisms.
研究领域:
分析化学
·
生物化学
·
药学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ACS Applied Polymer Materials
·
2023
·
IF 5
Jia Deng,Xiaojing Yuan,Lian Wang,Yanqi Sun,Hao He,Zhenyi Wu,Zibin Gao,Jingou Ji,Bochu Wang,Shilei Hao
Autogenous keratin is a promising material for personalized wound healing applications. However, the common keratin extraction methods are time-consuming, and the variations in performance between different individual keratins are not clear. Herein, we developed TiO2 photocatalytic-assisted H2O2 oxidation strategy (H2O2/TiO2/UV), an advanced oxidation method, to rapidly extract human hair keratins within 2 h. The H2O2/TiO2/UV method for keratin extraction showed a higher protein yield compared to the H2O2 method. Keratins obtained from the developed method exhibited typical chemical and secondary structures. Furthermore, individual keratins from four young girls were extracted by using the H2O2/TiO2/UV method, and individual keratin/PCL films were successfully fabricated within 5 h. More importantly, individual keratin films displayed superior hemostatic performance and wound healing in vivo compared to that of keratin extracted via the H2O2 method. Interestingly, the four individual keratin films exhibited similar hemostatic efficiency but distinct wound-healing properties in terms of epidermal thickness and density of skin appendages. These data indicated that the developed H2O2/TiO2/UV method is an efficient and feasible approach to extract human hair keratins, which provides an intriguing possibility to explore personalized materials for promoting wound healing.
研究领域:
材料科学
·
生物医学工程
·
化学工程
·
组织工程
✓ 已验证
DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2024
·
IF 13.3
Ming Zhang,Shenglin Yang,Weijie Zhong,Huimin Wang,U.T. Uthappa,Ben Wang
The escalating spread of micro/nanoplastics (MPs/NPs), originating from plastic waste fragmentation in the environment, is a growing global concern with detrimental effects on aquatic ecosystems. Previous methods for MPs/NPs treatment/removal poses significant challenges such as filtration, sedimentation efficiency, potential introduction of additional pollutants and expensive fabrication steps. In the current work, for the first-time keratin (KER)-based biohybrid micro/nanorobots obtained by facile decorations of iron-oxide microspheres with magnetic capabilities designed to dynamically remove (MPs/NPs) through various chemical/physical interactions, precise magnetic actuation, and improved surface functionalities. By integrating iron-oxide microspheres , keratin biohybrids achieve accurate motility and manipulation via external magnetic field regulation. This fuel free keratin magnetic micro/nanorobots (KMNRs) exhibit notable adsorptive removal efficiencies of 95% and 82% for (MPs/NPs) in water, offering diverse potentiality. Additionally, KMNRs demonstrated excellent recyclability, enhancing their sustainability. With eco-friendly, cost-effective, and real-world application attributes, designed KMNRs present an appealing approach to addressing MPs/NPs pollution.
研究领域:
环境科学
·
材料科学
·
纳米技术
·
废物管理
✓ 已验证
产品关联
DOI
高影响因子
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
·
2023
·
IF 6.8
Yunyang Li,Na Zheng,Siyu Sun,Sujing Wang,Xiaoqian Li,Jiamin Pan,Muyang Li,Le Lang,Zelin Yue,Binbin Zhou
Parabens (PBs), a class of endocrine-disrupting chemicals (EDCs), are extensively used as additives in personal care products (PCPs); however, distinguishing between endogenous and exogenous contamination from PCPs in hair remains a challenge. We conducted a comprehensive analysis of the levels, distribution patterns, impact factors, and sources of PBs in 119 human hair samples collected from Changchun, northeast China. The detection rates of methylparaben (MeP), propylparaben (PrP), and ethylparaben (EtP) in hair samples were found to be 100%. The concentration of PBs in hair followed the order of MeP (57.48 ng/g) > PrP (46.40 ng/g) > EtP (6.80 ng/g). The concentration of PrP in female hair was significantly higher (65.38 ng/g) than that observed in male hair (7.82 ng/g) ( p < 0.05). The levels of excretion rates of MeP ( ER MeP ) and excretion rates of PrP (ER PrP ) in the hair-dying samples (ER MeP : 17.89 ng/day; ER PrP : 14.15 ng/day) were found to be 2.52 and 2.40 times higher, respectively, compared to the non-hair-dying samples (ER MeP : 7.09 ng/day; ER PrP : 6.05 ng/day). However, the system exposure dosage (SED) results revealed that although hair dyes exhibited higher PBs, human exposure was found to be lower than certain PCPs. The results of the correlation analysis revealed that toner, face cream, body lotion, and hair conditioner were identified as the primary sources of PBs in male hair. Furthermore, the human exposure resulting from the utilization of female hair dye and serum exhibited a positive correlation with hair ER MeP and ER PrP levels, indicating in the screening of samples, excluding hair samples using hair dye and haircare essential oil can effectively avoid the interference caused by exogenous contamination from PCPs.
研究领域:
环境科学
·
公共卫生
·
毒理学
·
化学分析
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）