Materials Today Chemistry
·
2023
·
IF 7.3
S. Jiang,H. Zhang,Z. Li,L. Chen,L. Yin,X. Liu
Non-invasive sweat detectors can monitor the glucose level of diabetes in a painless way. However, most detectors need to collect enough sweat through external exercise or active stimulation, which increases the inconvenience of the user and reduces the applicable population. In this study, we propose an ultra-sensitive biomimetic glucose detector to detect the sweat produced by thermoregulation without additional exercise and stimulation. Inspired by the predator process of sponge in the sea, the sensing material of MXene (Ti 3 C 2 T x ) @CeO 2 hydrogels employed the “laminae-trestle-laminae” (L-T-L) structure of sponge to adsorb and transport glucose molecules in sweat. CeO 2 grafted onto the MXene surface can detect glucose by the catalytic activity of CeO 2 . The glucose detector with an ultra-low limit of detection (LOD = 0.004 μM), excellent sensitivity (801.27 μA⋅μM − 1 ⋅cm − 2 ), and a broad linear detection range (LDR = 0.01–2.5 μM) can satisfy detection requirements in human sweat after dilution. In real applications, the detector can detect glucose in the sweat of diabetic patients for five consecutive days and detect the glucose content in the daily drinks of patients. Our findings demonstrate the high potential of sponge-inspired MXene@CeO 2 glucose detector for routine medical testing.
研究领域:
生物医学工程
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材料科学
·
医学检测
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DOI
高影响因子
JOURNAL OF CHROMATOGRAPHY A
·
2021
·
IF 4.759
Canhong Zhu,Jiani Wu,Xueting Jin,Yinghua Yan,Chuan-Fan Ding,Keqi Tang,Di Zhang
Chemical modification of biological materials is indispensable for enrichment of phosphorylated peptides. In this work, we synthesized a biomimetic honeycombed affinity chromatography (IMAC) adsorbent by preparing Crosslinked Chitosan, chelating aminomethyl phosphate decorated with Ti (IV) cation. The as-prepared CTSM@AMPA-Ti 4+ composites with stable structure, low steric hindrance, and high Ti 4+ loading amount were used as a promising adsorbent for enrichment of phosphopeptides. CTSM@AMPA-Ti 4+ showed extremely high sensitivity (0.4 fmol) and selectivity at a low composition molar ratio of β-casein/BSA (1:1000). What's more, it can keep its performance in the case that used to capture phosphorylated peptides from standard protein ten times or soaking in the acid/base solution for a long time. In addition, CTSM@AMPA-Ti 4+ successfully captured 35 phosphorylated peptides from human saliva. This study offers a way about diversiform functionalization of CTSM in phosphoproteome analysis and disease research.
研究领域:
生物化学
·
分析化学
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DOI
高影响因子
ACS Applied Materials & Interfaces
·
2019
·
IF 8.456
Hao Chen,Xiuyan Ren,Guanghui Gao
In recent years, nature-inspired conductive hydrogels have become ideal materials for the design of bioactuators, healthcare monitoring sensors, and flexible wearable devices. However, conductive hydrogels are often hindered by problems such as the poor mechanical property, nonreusability, and narrow operating temperature range. Here, a novel skin-inspired gel is prepared via one step of blending polyvinyl alcohol, gelatin, and glycerin. Due to their dermis-mimicking structure, the obtained gels possess high mechanical properties (fracture stress of 1044 kPa, fracture strain of 715%, Young’s modulus of 157 kPa, and toughness of 3605 kJ m–3). Especially, the gels exhibit outstanding strain-sensitive electric behavior as biosensors to monitor routine movement signals of the human body. Moreover, the gels with low temperature tolerance can maintain good conductivity and flexibility at −20 °C. Interestingly, the gels are capable of being recovered and reused by heating injection, cooling molding, and freezing–thawing cycles. Thus, as bionic materials, the gels have fascinating potential applications in various fields, such as human–machine interfaces, biosensors, and wearable devices.
研究领域:
材料科学
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生物医学工程
·
柔性电子
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产品关联
DOI
PubMed
高影响因子
Polymers
·
2019
·Vol. 11
·期 11
·1892
·
IF 3.164
Luhao Wang,Bin Luo,Danni Wu,Yi Liu,Li Li,Hongguang Liu
Intelligent responsive materials have become one of the most exciting fields in the research of new materials in the past few decades due to their practical and potential applications in aerospace, biomedicine, textile, electronics, and other relative fields. Here, a novel thermal-responsive biomimetic shape memory wood composite is fabricated utilizing polycaprolactone-based (PCL) shape-memory polymer to modify treated-wood. The shape memory wood inherits visual characteristics and the unique three-dimension structure of natural wood that endows the shape memory wood (SMW) with outstanding tensile strength (10.68 MPa) at room temperature. In terms of shape memory performance, the shape recovery ratio is affected by multiple factors including environment temperature, first figuration angle, cycle times, and shows different variation tendency, respectively. Compared with shape recovery ratio, the shape fixity ratio (96%) is relatively high and stable. This study supplies more possibilities for the functional applications of wood, such as biomimetic architecture, self-healing wood veneering, and intelligent furniture.Keywords:shape memory wood;thermal-response;biomimetic materials;interface bonding
研究领域:
材料科学
·
仿生学
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产品关联
DOI
PubMed
高影响因子
ADVANCED FUNCTIONAL MATERIALS
·
2019
·Vol. 29
·期 28
·1901058
·
IF 15.621
Zenghe Liu,Luzhi Zhang,Qingbao Guan,Yifan Guo,Jiaming Lou,Dong Lei,Shuliang Wang,Shuo Chen,Lijie Sun,Huixia Xuan,Eric Meade Jeffries,Chuanglong He,Feng-Ling Qing,Zhengwei You
Natural tissues possess superior material properties such as self-healing, mechanical robustness, and mechanical gradients that allow organisms to adapt and survive in dangerous environments. Although highly desired, imparting synthetic materials with these biomimetic protective features remains a challenge. Here, the versatile dimethylglyoxime–urethane (DOU) moiety is used to create a multifunctional polyurethane (DOU-PU). The reactivities of DOU including reversible dissociation, metal coordination, photolysis enabled self-healing, high strength and toughness, mechanical gradient formation, and spatially controlled functionalization. By incorporating DOU, a multifunctional protective film is produced with superior resistance to mechanical damage, rapid room temperature self-healing, and anti-counterfeiting features. This super biomimetic film is expected to be very useful for the protection of various types of valuable objects such as electronics, diplomas, currency, and automobiles.
研究领域:
材料科学
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生物医学工程
✓ 已验证
产品关联
DOI
高影响因子
Materials
·
2022
·Vol. 15
·期 15
·5351
·
IF 3.748
Jinyi Wu,Quantao Liu,Shaopeng Wu
Cracks are inevitable during the service life of asphalt pavement and the water at the fracture surfaces tends to cause the grouting materials to fail. Studies have shown that the catechol groups in adhesion proteins secreted by mussels can produce strong adhesion performance in the water. In this paper, the mussel-like adhesive L-Dopa Methacrylic anhydride (L-DMA) was prepared based on the concept of bionic design and used to improve the properties of asphalt. By using Fourier-transform infrared spectroscopy (FTIR) and Thermogravimetric analysis (TGA), the thermal stability and structural composition of L-DMA were investigated. Then, the rheological and low-temperature properties of L-DMA-modified asphalt were investigated using the dynamic shear rheological (DSR) test and bending beam rheological (BBR) test. Moreover, the modification mechanism was explored by FTIR. It was found that L-DMA can be effectively synthesized and has good thermal stability. The incorporation of L-DMA increases the composite modulus, viscosity, creep recovery rate and rutting factor of asphalt binder, resulting in an enhancement of its high-temperature performance. At a high L-DMA content of 10%, the low-temperature performance of the modified asphalt was enhanced. The modification of L-DMA to asphalt is mainly a physical process. Hydrogen bonds and conjugated systems generated by the introduction of catechol groups enhance the adhesion properties of asphalt. In general, L-DMA improves the properties of asphalt and theoretically can improve the water resistance of asphalt, which will be explored in future research.Keywords:L-DMA;mussel bionic materials;modified asphalt;modification mechanism;rheological properties
研究领域:
材料科学
·
道路工程
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化学工程
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产品关联
DOI
PubMed
高影响因子
Materials Advances
·
2024
·
IF 5.2
Yuncheng Xu,Jun Tong,Jingxian Zhang,Yuting LI,Xiaowen Shi,Hongbing Deng,Y. Du
To design hydrogels with hierarchically ordered structure is of significance for biomimetic applications through simulating natural biological soft tissues. Due to the soft and fragile features of the hydrogel, it is challenging to create complex structure with modulated orientation in a facile and continuous way. In this study, we developed a novel method to electro-assemble natural polymeric hydrogels on non-conductive surface, which eliminating harsh pH change near the electrode during electrodeposition. Under optimal circumstances, charged polymeric chains packed densely in a continuous manner and aligned parallelly to the non-conductive surface. The oriented hydrogels can be peeled off from the non-conductive surface and demonstrate excellent mechanical property. We also found electric field intensity had a profound effect on the microstructure of the hydrogel. By programming the electric signals, we can construct complex structured hydrogels with regulated orientation, which should have potential applications in biomimetic material design.
研究领域:
材料科学
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生物医学工程
·
高分子化学
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产品关联
DOI
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2022
·
IF 8.025
Yueling Chen,Wenchao Yang,Zikang Hu,Xiaoyan Gao,Jingbiao Ye,Xiangqian Song,Baoshu Chen,Zhengqiu Li
Poly( l -lactic acid) (PLLA) displays simultaneous repair and regeneration properties. Therefore, it is vital for developing bone repair materials while improving their mechanical strength, and biocompatibility is essential for guaranteeing its application. In this manuscript, using solid hot drawing (SHD) technology to fabricate an oriented shish-kebab like structure, furthermore, the interface-oriented grain boundary controlled the nucleation site and cell morphology during low temperature supercritical carbon dioxide (SC-CO 2 ) foaming process, resulted in an oriented microcellular structure which was similar to load-bearing bone. The tensile strength, elastic modulus, and elongation at break of the oriented microcellular PLLA were 98.4 MPa, 3.3 GPa, and 16.4%, respectively. Furthermore, the biomimetic structure improved osteoblast cells (MC3T3) attachment, proliferation, and propagation. These findings may pave the way for designing novel biomaterials for bone fixation or tissue engineering devices.
研究领域:
生物医学工程
·
材料科学
·
组织工程学
✓ 已验证
DOI
PubMed
高影响因子
APPLIED SURFACE SCIENCE
·
2022
·
IF 7.392
Wang Zhiheng,Dai Yimin,Fang Chengqian,Chen Ling,Lu Qi,Li Yaqi,Cai Ling,Liu Bo,Zhang Yue-Fei,Li Yan,Wan Li
Smart oil-water separation materials with stimuli-responsive wettability surfaces have attracted wide attention. In this paper, a novel, simple and low-cost method is developed to prepare a pH-responsive melamine sponge (MS) with switchable wettability . This approach involves the hydrophobic modification of hexadecyltrimethoxysilane (HDTMS) on the MS surface modified by polydopamine (PDA) and the Michael addition reaction and Schiff base reaction between 12-aminododecanoic acid (NH 2 (CH 2 ) 11 COOH) and PDA. Hydrophobic/oleophilic HDTMS and pH-triggered NH 2 (CH 2 ) 11 COOH enable the functionalized sponge to repeatedly switch between the two extreme wettability under different pH environments. Benefiting from the excellent 3D porous surface structure and smart wettability, the as-prepared sponge can be applied in the on-demand separation of various oil-water mixtures by adsorption or filtration with a separation efficiency over 98.5% and high absorption capacity of 72.7–161.3 g·g −1 . With the assistance of pump-driven, continuous adsorption separation can be achieved in two cases by utilizing the wettability transformation. Moreover, in an alkaline solution, the sponge can quickly release most of the absorbed oil, showing a controllable desorption process. This smart wettability material with simple preparation and green has application potential in controllable oil-water separation and on-demand oil-spills treatment.
研究领域:
材料科学
·
环境科学
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DOI
高影响因子
MACROMOLECULAR CHEMISTRY AND PHYSICS
·
2017
·Vol. 218
·期 16
·1700206
·
IF 2.5
Zelin Wu,Liang Li,Youbing Mu,Xiaobo Wan
In this study, an effective way is presented to synthesize a mussel-inspired adhesive from two inexpensive commercially available materials: polyvinyl alcohol (PVA) and 3,4-dihydroxybenzoic acid via the esterification reaction and deprotection technology. This bioinspired adhesive exhibits good bonding ability on metal, glass, plastic, and wood, and the maximum bonding strength can be up to 4.0 MPa at dry conditions on glass substrate. Meanwhile, this adhesive can also be used as a wet/underwater adhesive. Such a PVA-based bioinspired adhesive may be used as a potential candidate for applications in industrial field.
研究领域:
材料科学
·
生物化学
✓ 已验证
产品关联
DOI
高影响因子
Matter
·
2024
·
IF 17.3
Xi Chen,Fengkai Liu,Qifeng Yu,Meng Yang,Zhigang Suo,Jingda Tang
Bovine pericardium, a tissue commonly used to make artificial heart valves, fulfills two fundamental mechanical requirements: a low modulus to ensure opening and closing in cyclic pulsatile flow and a high fatigue threshold to prevent crack growth. The tissue consists of a soft matrix and crimped fibers. Inspired by this architecture, we develop a composite of a soft polymer matrix and a knitted fabric. When the stretch is small to modest, the knitted fabric is easily stretched, so that the composite is soft. When the stretch is large, the knitted fabric is stiff and strong, so that the composite resists fatigue crack growth. The mechanical behavior of the composite is comparable to that of bovine pericardium. The composite has an exceptionally long fatigue life, enduring 25 million cycles of pulsatile flow, two orders of magnitude longer than the polymer matrix. This soft and fatigue-resistant composite may find broad applications in biomedicine.
研究领域:
生物医学工程
·
材料科学
✓ 已验证
产品关联
DOI
高影响因子
DYES AND PIGMENTS
·
2024
·
IF 4.1
Changwu Zheng,Xufang Zhang,Aiqin Gao,Meng Ju,Aiqin Hou,Kongliang Xie
Advanced biomimetic materials with tunable luminescence and changeable color have received immense attention for their great potential in various photonic applications. Herein, we fabricate two naphthalimide (NA)-functionalized spiropyran (SP) photoswitch molecular materials containing intramolecular energy donor-acceptor combinations (SP–N1, SP-N2), which have the adjustable multimodality fluorescence emissions and gradient photochromism. The intramolecular fluorescence resonance energy transfer within the excited states can be realized via designing the proximal distance between spiropyran and naphthalimide chromophore groups and their structure conversion, whereby the multimodality fluorescence emission can be generated. The color and intensity of fluorescence emissions are regulated by designing energy donor and acceptor system. The detailed spectroscopic and time-dependent density functional theory (TD-DFT) studies demonstrate that the effective photoconversion between SP-NA and the corresponding open structure merocyanine (MC) isomers (MC-NA) is facilitated by the large free volume induced by the rigid conjugation planes of the molecules. The PET composite films containing functional molecules have adjustable multimodal fluorescence emissions and variable photoinduced color. They are applied in multi-level anti-counterfeiting, and the patterns with the multi-signal output mode greatly enhance the level of anti-counterfeiting. The biomimetic materials with tunable luminescence and variable colors have potential applications in complex information encryption , advanced anti-counterfeiting, and optical devices.
研究领域:
材料科学
·
光学
·
生物仿生学
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）