CHEMICAL ENGINEERING JOURNAL
·
2024
·
IF 13.3
Yugui Cheng,Simian Fu,Kaiming Jin,Yiying Liu,Jingtong Ma,Deliang Li,Qingying Lyu,Yehan Li,Xiaoyang Jiang,Ruonan Liu,Ye Tian
Hydrogels displaying both high toughness and flexibility hold substantial practical value. However, it has been challenging to achieve these properties simultaneously. To address this challenge, we developed a special structure hydrogel named PAB-S inspired by chrysalis shell. Astragalus polysaccharide (AP) was copolymerized with polyvinyl alcohol (PVA) and betaine hydrochloride (BH) to prepare a low-modulus hydrogel, PAB. Subsequently, surface modification of the PAB hydrogel using sodium phytate (SP) resulted in the formation of the “shell” structured PAB-S hydrogel. The fracture strength of the shell-structured hydrogel increased by about 0.8 MPa. Meanwhile, PAB-S had a maximum tensile strain of 418 %, a toughness of 6.82 MJ/m 3 , and a modulus of elasticity of approximately 0.6 MPa. In addition, PAB-S hydrogel offers high strain sensitivity (GF up to 4.7), ultra-low response time of 20 ms. Finally, leveraging 2.4G communication technology and a deep learning (1D-CNN) algorithm, advanced functionalities such as wireless remote intelligent control, and deep learning-based finger grip disorder identification were realized using the PAB-S hydrogel sensor. The PAB-S hydrogel sensor holds promising prospects for applications in fields including deep learning, intelligent sensing, medical rehabilitation, and human–machine synchronization.
研究领域:
材料科学
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生物医学工程
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传感器技术
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF APPLIED POLYMER SCIENCE
·
2024
·Vol. 141
·期 30
·e55701
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IF 2.7
Chaojie Chen,Guoqing Cui,Yuanlong Li,Li Liu,Guangfeng Wu
Developing antiswelling hydrogel that retains their low modulus and has three-dimensional (3D) printability to application in the biomedical field is a current critical issue. Here, we synthesized 3D printing ink consist of poly(acrylic acid-acrylamide-allyloxypolyethyleneglycol) (P(AA-Am-APEG)) and nanosilica (SiO 2 ) by free radical polymerization, immersed the hydrogel precursor printed by ink in ferric chloride solution to prepare a low modulus, antiswelling, and conductive hydrogel. In the physical cross-linking network, the coordination interaction and hydrogen bonds contributed to excellent mechanical properties and nSiO 2 regulated rheological behavior of ink. Especially, P(AA-Am-APEG) molecular chain was a structure containing of APEG branch chain, which could endow antiswelling (the equilibrium swelling rate was only 7% in deionized water) and low modulus (Young's modulus was less than 100 kPa) to hydrogel. The tensile stress could still maintain 90% of the original value after soaking for 24 h. In addition, the existence of iron and chloride ions provided high sensitive deformation-dependent conductivity to hydrogel. Therefore, the strategy of controlling the swelling and modulus by branch chains would expand the application of hydrogel in biosensors and other fields.
研究领域:
生物医学工程
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材料科学
✓ 已验证
产品关联
DOI
高影响因子
Smart Materials and Structures
·
2025
·
IF 3.8
Qinqin Wang,Changgeng Shuai,Xue Yang,Weibin Wu,Gang Lu
Dielectric elastomers (DEs) are highly valued in massive fields of actuators and sensors due to their unique advantages of large actuation strain, fast response speed, high energy density and excellent elasticity. The challenge of balancing the elastic modulus, actuation strain and response speed of DE actuators to stably enhance the actuation performance remains a major issue. In this work, a novel DE was prepared by employing polyurethane acrylate (CN9021) as a crosslinker, n-butyl acrylate (BA) as a base monomer and 2-ethylhexyl acrylate (2-EHA) as a functional flexible monomer via a UV curing method. The swelling test indicates a reduction of crosslinking density with the increment of 2-EHA concentration in EHA films. As a consequence, the elastic modulus displays a notable decline while the dielectric constant slightly rises, leading to an enhancement of the actuation sensitivity. More specifically, the elastic modulus of our fabricated EHA-1 is only one-third of the commercial VHB-4910. The developed DEs achieve an actuation strain of nearly 150% with low viscoelasticity and mechanical loss resulting in high response speed and broad operating frequency range to the input dynamic voltages. All these actuation performances are superior to VHB-4910. This work provides a promising strategy for developing DEs with balanced performance and superior actuation characteristics.
研究领域:
材料科学
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智能材料
·
高分子化学
✓ 已验证
产品关联
DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2024
·
IF 13.3
Jiani Xu,Tingwei Cai,Hanchang Hu,Chen Meng,Xia Dong,Qiangqiang Zhao,Jinxin He
This work primarily discusses the construction of physically cross-linked polyacrylamide copolymer containing 2-(3-(6-methyl-4-oxo-1,4-dihydropyrimidin-2-yl)ureido)ethyl methacrylate (PAM-co-UPyMA, short for PAU) hydrogels with topological entanglement by designing high concentrations of acrylamide (AM) monomers and introducing “bridging” flexible non-covalent bonds. This method overcomes the poor stretchable performance of chemically cross-linked hydrogels, as well as the limited improvement in mechanical properties due to the low dissipation energy of physically cross-linked hydrogel (non-covalent bonding) under an external force. This new hydrogel exhibits low modulus (0.12 MPa), a certain fracture strength (0.2 MPa), and high toughness with an elongation at a break of 5700 %, demonstrating excellent tensile strain sensitivity with a gauge factor (GF) of 16.14, capable of detecting tiny deformations of 0.2 %. It also exhibits fast strain response, long-term stability, and performs well in applications such as human joints and voice monitoring. Furthermore, this work elucidates the relationship between the microstructure of PAU hydrogels and sensing performance, proving that the rate of microstructure change serves as an essential mechanism. The less cross-linked and highly entangled PAU hydrogel strain sensor increases the cross-linked domain size under tensile load, leading to ion channel blockade with a rapid increase in resistance during deformation, thus resulting in an improved sensitivity.
研究领域:
材料科学
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生物医学工程
✓ 已验证
产品关联
DOI
高影响因子
CARBOHYDRATE POLYMERS
·
2020
·
IF 7.182
Hongyao Ding,Xiaoxu Liang,Qiao Wang,Miaomiao Wang,Zongjin Li,Guoxing Sun
There is a growing demand for hydrogel-based sensors due to their biomimetic structures and properties, as well as biocompatibility. However, it is still a challenge to fabricate hydrogel sensor with integration of good mechanical properties and high conductivity. Herein, a tough and conductive hydrogel is developed with semi-interpenetrating network formed by incorporating carboxymethyl chitosan and sodium chloride into polyacrylamide network. The hydrogels have high tensile strength, elongation and toughness, but low modulus comparable to human skin. In addition, the hydrogels exhibit fast self-recovery and satisfactory self-healing capabilities. Owing to the existence of sodium chloride, the hydrogel also has high conductivity, good water retention property and anti-freezing ability. When used as a strain sensor, it demonstrates a broad strain window and shows a high sensitivity in monitoring human motions. This work provides a facile method in fabricating multifunctional ionic conductive hydrogel for applications in wearable electronics and soft robotics.
研究领域:
材料科学
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生物医学工程
·
柔性电子学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ADVANCED MATERIALS
·
2025
·
IF 26.8
Ganguang Yang,Bin Xie,Jia Tian,Yue Zhang,Yutian Liu,Hangyu Gong,Bo Pang,Yuqi Qiu,Caixin Gong,Tianzhao Bu,Zhouping Yin,Hao Wu
Thermotherapy has demonstrated considerable potential in accelerating wound healing by promoting cellular repair and blood circulation. However, existing systems demonstrate nonadjustable adhesion, poor thermal uniformity, etc., substantially hindering widespread applications. Here, a wireless thermotherapy system with adhesion-customizable hydrogel interfaces is developed for accelerating wound healing. The hydrogel layer exhibits ultra-low modulus (0.29 kPa) and superior adhesion (15.58 kPa) with wide-range regulation capability (>8-folds). Flexible heating layers with anisotropic serpentine-mesh structures are further prepared, demonstrating high transparency (87.73%) and low resistance (3.83 Ω) for uniform heating. By integrating hydrogel patches with wireless circuits, a hydrogel thermotherapy system is fabricated for high-precision closed-loop temperature control (accuracy: ±0.1 °C). Animal experiments show that this system enables strong adhesion for rapid wound positioning during thermotherapy, maintaining gentle adhesion for conformal contact to avoid wound stress concentration and ensure uniform heating, while realizing low adhesion for benign post-therapy disassembly without wound damage. The wound healing rates reach 99.58% on day 14, which is 15% higher than that in the control group, along with a ≈4-day reduction in healing time. Histopathological analysis further validates the effectiveness of this system in accelerating wound healing. The wireless hydrogel thermotherapy system represents a promising platform for wound management.
研究领域:
生物医学工程
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伤口护理
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智能治疗
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柔性电子
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水凝胶材料
✓ 已验证
产品关联
DOI
PubMed
高影响因子
POLYMER TESTING
·
2022
·
IF 4.931
Zhaoxia Luo,Liqun Zhang,Yongri Liang,Shipeng Wen,Li Liu
To achieve high deformation under a low electric field intensity is still a big challenge for the dielectric elastomers (DE) potentially used in artificial electronic skin and artificial muscles. Herein, poly-dopamine (PDA) modified 1D barium titanate (BT@PDA) nanofibers and 2D MXene nanosheets with high aspect ratio and large dipole moment were fabricated, and introduced into TPU elastomers. Results showed that the interfacial polarization and micro-capacitor structure formed by MXene sheets lead to the high dielectric constant, and high dielectric loss of MXene/TPU composites with low modulus. The interfacial polarization caused by BT@PDA nanofibers resulting in high dielectric constant and low dielectric loss of BT@PDA/TPU composites with high modulus. Combing the advantages of the two fillers, the MXene/BT@PDA/TPU composites showed high dielectric constant, low dielectric loss, low modulus. The electrical sensitivity factor of 0.5 wt% MXene/5 wt% BT@PDA/TPU composite (11.38) was much higher than the sum of that of 0.5 wt% MXene/TPU (1.73) and 5 wt% BT@PDA/TPU (4.35) composites at a low filler content, showing the 0.5 wt% MXene/5 wt% BT@PDA/TPU dielectric composite had a large deformation under a low electric field. This work can provide an effect strategy to design DE nanocomposites with good deformation performance.
研究领域:
材料科学
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纳米技术
·
电气工程
✓ 已验证
产品关联
DOI
高影响因子
ACS Applied Materials & Interfaces
·
2023
·
IF 9.5
Haizhou Huang,Jiaxin Shen,Shu Wan,Longxiang Han,Guangbin Dou,Litao Sun
A stable and seamless adhesion between the human skin and the hydrogel-based electronic skin is necessary for accurate sensing and human health monitoring in aquatic environments. Despite achieving significant progress in this field, it remains a great challenge to design skin-interfaced conductive hydrogels with high electrical conductivity, stablility, and seamless underwater adhesion to skin. Herein, a skin-inspired conductive multifunctional hydrogel is proposed, which has a wet-adhesive/hydrophilic and a non-adhesive/hydrophobic bilayer structure. The hydrogel shows high stretchability (∼2400%) and an ultra-low modulus (4.5 kPa), which facilitate the conformal and seamless attachment of the hydrogel to the skin with reduced motion artifacts. Owing to synergistic physical and chemical interactions, this hydrogel can achieve reliable underwater adhesion and display remarkable underwater adhesion strength (388.1 kPa) to porcine skin. In addition, MXene has been employed to obtain high electrical conductivity, create a route for stable electron transport, and reinforce mechanical properties. The hydrogel also possesses self-healing ability, a low swelling ratio (∼3.8%), biocompatibility, and specific adhesion to biological tissues in water. Facilitated with these advantages, the hydrogel-based electrodes achieve reliable electrophysiological signal detection in both air and wet conditions and demonstrate a higher signal-to-noise ratio (28.3 dB) than that of commercial Ag/AgCl gel electrodes (18.5 dB). Also, the hydrogel can be utilized as a strain sensor with high sensitivity for underwater communication. This multifunctional hydrogel improves the stability of the skin–hydrogel interface in aquatic environments and is expected to be promising for the next-generation bio-integrated electronics.
研究领域:
材料科学
·
生物医学工程
·
电子学
·
生物技术
·
纳米技术
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）