Journal of Materials Chemistry B
·
2022
·Vol. 10
·期 6
·915-926
·
IF 7.571
Liwei Zhang,Yajie Zhang,Fanshu Ma,Xingzhu Liu,Yangzhong Liu,Yi Cao,Renjun Pei
Hydrogel-based wound dressings with tissue adhesion abilities are widely used for wound closure. However, currently developed hydrogel adhesives are still poor at continuing to seal wounds while bleeding is ongoing. Herein, we demonstrate an antibacterial and hemostatic hydrogel adhesive with low-swelling properties and toughness for wound healing. The hydrogel was composed of Pluronic F127 diacrylate, quaternized chitosan diacrylate, silk fibroin, and tannic acid, and it was not only able to maintain good tissue adhesion abilities in a moist environment but it also showed guaranteed tissue adhesion and mechanical strength after absorbing water due to its low-swelling and toughness properties. Furthermore, in vitro and in vivo tests demonstrated that the hydrogel also had antibacterial, antioxidant, and hemostatic properties, which could promote tissue regeneration. All these findings demonstrate that this hydrogel with multifunctional properties is a promising material for clinical wound healing applications.
研究领域:
生物医学工程
·
材料科学
·
组织工程
✓ 已验证
DOI
PubMed
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2018
·
IF 6.735
Mingji Su,Yong Liu,Shihong Li,Zhengping Fang,Benqiao He,Yuhong Zhang,Yulin Li,Peixin He
Hydrogel has been widely applied in agriculture, oil/water separation, and tissue engineering due to its hydrophily and three-dimensional network structure. But its practical applications are restricted by their non-reversible deformation or poor mechanical property to a great extent. In this study, we prepared a rubber-like, interpenetrating-network poly(acrylamide-co-acrylic acid)/chitosan/methacryloxy propyl trimethoxyl silane modified SiO 2 nanocomposite hydrogel (P(AM-co-AA)/CS/MPS-SiO 2 nanocomposite hydrogel, SIPN-Gels) that exhibit feature underwater superoleophobicity, self-healing and low swelling ratio properties. The nanocomposite hydrogel has hierarchically porous structure and dense spherical papillae structures on its surface, which can improve oil-repellent capability and result in superoleophobicity and self-cleaning property. Besides, synergetic interactions of CS physical networks and MPS-SiO 2 crosslinked P(AM-co-AA) covalent network endows the hydrogel with rubber-like mechanical property (high elasticity, fast self-recovery after large tensile or compression deformation), superior to most of reported underwater superoleophobic hydrogels. To apply this hydrogel for efficient oil/water separation, the obtained underwater superoleophobic hydrogel is further coated on a stainless-steel mesh as separator, we believe that the rubber-like nanocomposite hydrogel will inspire researchers to design flexible and wearable oil-repellent or oil/water separation materials.
研究领域:
材料科学
·
环境工程
·
生物医学工程
✓ 已验证
产品关联
DOI
高影响因子
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
·
2022
·
IF 5.518
Xiaojing Zhang,Bo Liu,Wenbo Feng,Wangchong Wei,Weiwei Shen,Shaoming Fang,Kaiqi Fan
Conductive composite hydrogels are attracting much attention as artificial skin-like materials, with great potential for applications in wearable electronics, flexible printable electronics, and tissue engineering scaffolds. However, the design of conductive hydrogels possessing multifunctional properties such as excellent mechanical properties , self-healing, high conductivity, low swelling ratio (SR), and high strain sensitivity remains a challenge. Here, we designed and synthesized a polyhedral oligomeric silsesquioxane (POSS)-based composite hydrogel (OCAPS/PAA–Na/PAM) via the copolymerization of acrylamide and an ionic supramolecular monomer consisting of a cationic octa(3–chloroammoniumpropyl) silsesquioxane (OCAPS) core surrounded by sodium acrylate to achieve a combination of high stretchability, low SR, self-healing, high conductivity, biocompatibility, and strain sensing properties. The introduction of OCAPS as a physical crosslinking agent enhanced the toughness and compression properties of the hydrogel. The SR of the OCAPS/PAA–Na/PAM hydrogel was greatly suppressed, with a much lower value (SR: 200 %) than that of the hydrogel without POSS (SR: ~22,000 %). The elongation at break and fracture energy reached 4396 % and 3.7 kJ·m −2 , respectively. OCAPS/PAA–Na/PAM hydrogels also had good self-healing properties due to the sufficient electrostatic interactions and hydrogen bonding between OCAPS and the polymer chains. Moreover, the supramolecular monomers provided abundant ion sites and in-situ generated NaCl , which imparted good electrical conductivity (0.678 mS·cm −1 ) and excellent strain sensitivity (gauge factor = 3.78) to the hydrogel. The OCAPS/PAA–Na/PAM hydrogel could detect electrical signal changes in large strain and small limb deformation and they showed good biological transmission sensitivity, which is expected to contribute to the fields of safety detection, gait detection, and wearable devices .
研究领域:
材料科学
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生物医学工程
·
柔性电子
✓ 已验证
产品关联
DOI
高影响因子
Journal of Cleaner Production
·
2024
·
IF 9.7
Cuicui Wang,Yingying Jiang,Quan Ji,Yacheng Xing,Xiaomei Ma
Conductive hydrogels are considered to be promising materials for flexible electronics, but those nondegradable are bound to produce substantial undesirable electronic wastes once widely applied, inconsistent with the long-term sustainable development goals . To develop biodegradable conductive hydrogels for sustainable flexible electronics, a green chemical reaction-free strategy was developed to manufacture a novel type of composite hydrogels , exploiting biodegradable gellan gum and polyvinyl alcohol as the matrices and natural-derived tannic acid as the crosslinking agent. The technique involves successive cool-induced sol−gel transition, freeze-thawing and Na 2 SO 4 solution treatment. A universal electronic testing machine, scanning electronic microscope, X-ray diffractometer , thermogravimetric analyzer, and electrochemical work station were employed to study the mechanics, structure and morphology, swelling and conductivity of the hydrogels. The results indicate strong, elastic and tough hydrogels were achieved owing to the multi-crosslinked multiple-network structure. The maximum compressive stress (90% strain), tensile strength , breakage elongation and fracture energy reach 10.7 MPa, 1.2 MPa, 890% and 480 kJ/m 3 respectively. The stress recovery rate still remains 86% after 10 consecutive loading-unloading under 200% strain. The highest conductivity reaches 3.27 S/m, which along with the excellent mechanics confers them good strain-sensing behavior. Moreover, the final hydrogels show low swelling in both water (the equilibrium swelling ratio (E SR ) < 300%) and physiological saline (E SR < 90%). The excellent mechanical performance, high conductivity and good strain sensing, low swelling and inherent biodegradability as well as the ecofriendly manufacturing process imply potential prospect in sustainable flexible electronics.
研究领域:
材料科学
·
可持续发展
·
柔性电子学
✓ 已验证
产品关联
DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2019
·
IF 8.355
Liqing Li,Jinghua Zhao,Yiran Sun,Fei Yu,Jie Ma
Double-network gel is composed of two kinds of crosslinked organic/inorganic networks, which has a good prospect of environmental application and its application in the antibiotic removal has important practical significance. Novel polysaccharide-based double-network gel bead (SK) with low-swelling, enhanced mechanical properties and excellent adsorption capacity of ciprofloxacin hydrochloride (CIP) was prepared via a facile ionically cross-linking method. Mechanical properties tests and swelling experiments showed that the sorbent has an enhanced mechanical property with stress of 1.07 MPa and an elastic modulus of 1.3 MPa at 90% strain and a reduced swelling property compared to a single ĸ-CG/Ca 2+ network. The adsorption performances of SK gel for CIP were investigated by changing the ratio of raw materials, crosslinking agent concentration, adsorbent dosage, contact time, temperature, pH, and pollutant concentration systematically. The above studies indicated that the maximum adsorption capacity of 291.6 mg/g was obtained at pH = 5.1. The kinetic datas were well fitted to the pseudo-second-order model, indicating that chemical sorption was the rate-limiting step. The isotherm of adsorption could be described by the Langmuir-Freundlich model well, which showed that SK gel had heterogeneous surface and different binding sites. By analyzing FT-IR spectroscopy and the adsorption changes under different pH, the adsorption mechanism may be explained by hydrogen bonding and the electrostatic interactions between CIP and the adsorbent. This study highlighted that SK gel beads could be used as a promising adsorbent for the large-scale removal of CIP in aqueous solutions, and the research will be conducive to address CIP pollution efficiently.
研究领域:
环境科学
·
材料科学
✓ 已验证
产品关联
DOI
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2025
·
IF 8.5
Lei Song,Ashuang Liu,Sunjun Yang,Jingbo Yin,Rong Wang
Ionic conductive hydrogels have emerged as promising materials for constructing flexible wearable sensors due to their excellent flexibility, conductivity, and strain sensitivity. However, current hydrogel sensors face some important challenges, such as poor mechanical performance, high swelling ratios, and limited functionality, significantly hindering their applications. This study developed a poly(acrylic acid- co -acrylamide) (P(AA- co -AM)) hydrogel that was synergistically reinforced by phytic acid (PA) and carboxymethyl cellulose (CMC) (PAA/AM-PA-C ionic conductive hydrogel). The hydrogel demonstrated a tensile strength of 2.05 MPa and an elongation at break of 1081.93 %, along with good fatigue resistance. Additionally, it showed low swelling ratios in aqueous environments including in seawater, ensuring the hydrogel sensor exhibited exceptional strain-sensing capabilities in various conditions. As a flexible sensor, this hydrogel exhibited excellent sensitivity and stable sensing performance, providing precise and consistent responses to joint motion and speaking. Because of the addition of PA, the hydrogel also showed obvious anti-freezing properties, and can maintain good mechanical properties and sensing properties at −20 °C, broadening its applications in various conditions. In addition, the hydrogel showed remarkable antibacterial properties and biocompatibility, offering new avenues for the development of multifunctional hydrogel-based wearable sensors.
研究领域:
材料科学
·
生物医学工程
·
传感器技术
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF MOLECULAR STRUCTURE
·
2025
·
IF 4.7
Shiwen Zhang,Yang Zhang,Fan Zhang,Lulu Wang,Lingzhi Xiong,Shuanglong Xiao,Shaoji Wang,Jilin Wang
Crown ether, as a hydrophilic group, is capable of forming complexes with metal cations and serves as a key component for constructing supramolecular assemblies. This functionality allows it to dynamically capture anchor points, enhance ion aggregation, and improve the hydroxide conductivity. However, the high hydrophilicity of crown ether can lead to excessive swelling, which limits its application. Therefore, this study designs ether-free AEMs containing crown ether, m-terphenyls and piperidine through superacid-catalyzed synthesis, and are used in fuel cells. PMDTP-15 not only achieves efficient conduction of OH − (130.7 mS·cm −1 , 80 °C), but also effectively limits the swelling of the membrane (19.1 %, 80 °C) and exhibits excellent alkali stability (after being immersed in 1 M NaOH solution for 1680 h, the conductivity remained 95.34 %, and the mechanical properties decreased by 1.13 %) due to the high hydrophilicity and m-terphenyl torque structure of the crown ether structure. In addition, the peak power density of a single PMDTP-15 cell can reach 1043 mW·cm −2 , and the voltage can maintain 90 % of the original performance after 120 h.
研究领域:
材料科学
·
高分子化学
·
电化学
·
能源材料
·
膜科学
·
燃料电池技术
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF SEPARATION SCIENCE
·
2024
·Vol. 47
·期 17
·2400462
·
IF 2.8
Yang Yang,Yuexin Li,Yang Zhao,Changyu Cai,Xinmiao Liang,Yanxiong Ke
In this work, monodisperse organosilane hybrid polymer microspheres with a particle size of about 5 µm were synthesized using seed swelling polymerization. The organosilicon reagent methacryloxypropyltrimethoxysilane was introduced into the polymer framework as a copolymerization monomer, and the crosslinking degree of the microspheres was improved by the hydrolysis-condensation reaction of siloxanes. The synthesized hybrid microspheres have good mechanical strength as well as low swelling, with swelling propensity values of 0.167 and 0.348 in methanol and acetonitrile, respectively. Hybrid microspheres modified with cysteine have a hydrophilic interaction chromatography/reversed-phase liquid chromatography mixed-mode retention mechanism. Compared to the commercial cysteine-modified silica column, the synthesized stationary phase has higher separation selectivity for partially acidic or basic samples and better basic resistance for use under high pH mobile phase conditions (at least 10).
研究领域:
分析化学
·
材料科学
·
色谱学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）