MICROCHEMICAL JOURNAL
·
2025
·
IF 5.1
Yueru Chen,Zongning Guo,Xuelin Huang,Jiangying Qu,Feng Gao,Kai Wan,You Zhang,Xiaofang Zhao,Zhe Jiao
In this study, we designed a fluorescent Por-COF-MF, for selective detection SO 2 in wine. The fluorescence was quenched due to the intramolecular charge transfer (ICT) process blocked by SO 2 . A good linear relationship of fluorescent intensity with SO 2 in the concentration range of 0.01–1 ppm was found. To achieve facile solid-state detection, Por-COF-MF was loaded on polyvinyl alcohol (PVA) to fabricate a uniform fluorescent film Por-COF-MF@PVA. Then a portable device was designed by 3D printing technology. The device exhibited good linearity in the SO 2 concentration range of 0.5–3 ppm, with a detection limit of 0.06 ppm. The relative standard deviation (RSD) was less than 8 % when measuring SO 2 in three different types of wine. Compared to other portable technologies, our 3D-printed fluorescent device allowed for direct detection of SO 2 content in wine, which provided a more effective and economical method for food safety monitoring.
研究领域:
食品安全
·
化学传感器
·
材料科学
✓ 已验证
产品关联
DOI
高影响因子
FOOD CHEMISTRY
·
2025
·
IF 9.8
Jia Wu,Huimei Liang,Shulan Zeng,Shulin Zhao,Fanggui Ye
Pesticide residues pose significant risks to consumer health. Therefore, it is essential to develop convenient and practical detection methods. Nanozyme colorimetric sensing is widely used for pesticide detection. However, improving its sensitivity and selectivity remains a major challenge. In this study, a smartphone-assisted portable test swab fabricated using CuWO 4 as the extractant, combined with solid-phase extraction (SPE), was designed for the colorimetric detection of thiram (THR). Based on the specific binding between the Cu sites in CuWO 4 and THR, interference was eliminated after the SPE to improve selectivity. Moreover, the sensitivity improved after SPE enrichment. Additionally, THR enhanced the peroxidase-like activity of CuWO 4 , whereas tungsten as a co-catalyst further boosted the nanozyme activity, thereby improving the detection sensitivity (limit of detection: 19 nM). The experimental results demonstrate that this method exhibits high stability and good selectivity, with recoveries in real samples ranging from 90.8 % to 112.4 %.
研究领域:
分析化学
·
环境科学
·
食品科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Science China-Chemistry
·
2016
·Vol. 60
·期 2
·293-298
·
IF 2.429
Huang Yishun,Wu Xuemeng,Tian Tian,Zhu Zhi,Lin Hui,Yang Chaoyong
Lanthanide elements (Ln) play an important role in industry and agriculture. As a result of the increasing consumption of lanthanides, environmental emission of Ln has become detrimental to the health of flora and fauna. Current methods for trace lanthanides detection mainly rely on sophisticated instruments. In this article, a Ln 3+ dependent DNAzyme was incorporated into a hydrogel to generate Ln 3+ sensitive DNAzyme hydrogel for portable colorimetric detection. The enzyme strand and its substrate strand act as crosslinker and functional unit of the hydrogel with polyacrylamide chains as the scaffold and gold nanoparticles (AuNPs) as the indicator of hydrogel stability. Any ions in the Ln 3+ series can trigger the cleavage of substrate strand by activating the enzyme strand, thereby decreasing the crosslink ratio and leading to collapse of the hydrogel. The release of the encapsulated AuNPs turns the supernatant wine red. Using this colorimetric method, Ln 3+ can be detected with high sensitivity, with a limit of detection (LOD) of 20 nM for Ce 3+ . The hydrogel responds specifically to any Ln 3+ ion and works well with the spiked lake sample without the need of instruments and skilled operators. Our results suggest that the lanthanide responsive hydrogel can be used for portable and sensitive detection of Ln 3+ contamination in the field.
研究领域:
生物化学
·
环境科学
✓ 已验证
DOI
高影响因子
CERAMICS INTERNATIONAL
·
2025
·
IF 5.6
Zhe Sun,Heyu Li,Aaron S. Pittman,Yan Cao
Scandium is a rare earth element that is relatively scarce on Earth. The need for its rapid qualitative detection has increased dramatically owing to its extensive use in various high-tech sectors and potential environmental concerns. This work aims to develop a portable, simple, low-cost specific detection sensor for on-site qualitative detection of Sc 3+ ions. Multiple carbon dots were synthesized via the “bottom-up” hydrothermal method and characterized by morphology, structure, and optical properties. The characteristic structure of “salicylic acid” was determined as the core of the Sc 3+ selective detection function through precursor molecular engineering design. Further investigation was conducted into the impact of various factors on the Sc 3+ specific fluorescence detection performance of related derived carbon dots, including the electronic and spatial effects of various substituents on the aromatic skeleton of precursor molecules and the size of aromatic conjugated systems. The detection performance of carbon dots derived from different precursor sources was compared, and the optimal carbon dots derived from 2-hydroxy-3-naphthoic acid were selected, with a lower detection limit (4.38 ppb) and a significant blue shift (from green visible light to blue visible light range). On this basis, a portable device capable of detecting Sc 3+ ions, the 2-3-CDs PVA membrane, was developed. Our work presents the first discovery of carbon dots as Sc 3+ ion fluorescence sensors, providing new insights and beneficial results for subsequent rare earth element detection.
研究领域:
材料科学
·
环境科学
·
化学
✓ 已验证
DOI
高影响因子
Biosensors-Basel
·
2025
·Vol. 15
·期 5
·267
·
IF 5.6
Fei Wang,Xiao Peng,Ziqian Xiao,Ying Ge,Bilin Tao,Zhaoyong Shou,Yifei Feng,Jing Yuan,Liang Xiao
A composite (N-rGO@ppy) of N-doped reduced graphene oxide (N-rGO) coated with polypyrrole (ppy) particles was successfully synthesized. The incorporation of N-rGO significantly mitigates the aggregation of ppy synthesized in situ, and the doped N atoms improve the conductivity of graphene oxide (GO), thereby enhancing N-rGO@ppy’s redox properties. Firstly, a glassy carbon electrode (GCE) modified with N-rGO@ppy (N-rGO@ppy/GCE) was used in combination with a bismuth film and square-wave anodic stripping voltammetry (SWASV) for the simultaneous trace analysis of Pb2+and Cd2+. N-rGO@ppy/GCE exhibited distinct stripping peaks for Pb2+and Cd2+, with a linear range of 1 to 500 μg L−1. The limits of detection (LODs) were found to be 0.080 μg L−1for Pb2+and 0.029 μg L−1for Cd2+, both of which are significantly below the standards set by the World Health Organization (WHO). Subsequently, the same electrochemical sensing strategy was adapted to a more portable screen-printed electrode (SPE) to accommodate the demand for in situ detection. The performance of N-rGO@ppy/SPE for analyzing Pb2+and Cd2+in actual samples, such as drinking water, milk, and honey, showed results consistent with those obtained from conventional graphite furnace atomic absorption spectrometry (GFAAS).
研究领域:
分析化学
·
环境科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2025
·
IF 13.2
Tao Chen,Peng Liu,Yu Ge,Xiaoting Lei,Zhenzong Fan,Xiaoyu Zhu,Yangping Wen,Hassan Karimi-Maleh,Xiaoqiang Wang
Sesamol is a momentous marker for evaluating the quality of sesame or sesame products. In this study, a new strategy for fabricating portable smartphone sensor based on violet phosphorene (VP)/two-dimensional transition metal borides (MBene) nanozyme modified with Au − Ag bimetallic nanoparticles (Au − AgNPs) on the surface of the screen-printed electrode, which is synthesized under the guidance of machine learning (ML) with eXtreme Gradient Boosting (XGBoost) algorithms, is described for intelligent sensing of sesamol in farmland and agricultural fields. A fluorine-free hydrothermal-assisted alkane etching strategy is used to prepare the fence-like MoAlB-MBene. Highly environmentally stable VP/MoAlB-MBene nanozyme decorated by Au − Ag bimetallic nanoparticles is obtained by ultrasonic-assisted liquid-phase exfoliation with XGBoost assistance. The ML models including artificial neural network, support vector machine and XGBoost for the synthesis of nanozyme are contrasted and discussed, and the XGBoost algorithm is found as the most accurate model for synthesizing nanozyme due to the highest value of correlation coefficient. The nanozyme-modified screen-printed carbon electrode coupled with the palm-sized smartphone-controlled wireless electrochemical device as a portable wireless intelligent sensing platform for the determination of sesamol in a wider linear range of 0.1 ∼ 1000 μmol/L with a lower limit of detection of 21 nmol/L, which enable the on-site determination of 10 varieties of sesame seeds. This work will provide a new reference for the one-step preparation of bimetallic nanoparticles decorated graphene-like nanozyme guided by ML for cost-effective, simple, fast detection of phytochemicals in agricultural products using a portable smartphone sensor.
研究领域:
食品科学
·
材料科学
·
人工智能
·
分析化学
✓ 已验证
产品关联
DOI
高影响因子
FOOD CHEMISTRY
·
2025
·
IF 9.8
Rubing Zou,Qianyi Yu,Zexiang Wang,Peiyu Yang,Ying Zhao,Yihua Liu,Yan Fu,Yirong Guo
Unexpected interferences from the food matrix pose challenges to achieving high-performance on-site monitoring of pesticide residues. In this study, we employed 3D printing technology to fabricate a miniaturized lab-on-a-chip (LOC) device for in-situ sample pretreatment. Serving as the analytical component, a lateral flow immunochromatographic strip was developed for thiamethoxam, a representative neonicotinoid insecticide. Results showed that the composite LOC device enabled on-site determination of thiamethoxam in 13 different food samples using a multi-step analysis approach. Similar to the buffer-based calibration curve (IC 50 : 0.11 ng·mL −1 ), the matrix-based calibration curves for celery (IC 50 : 0.15 ng·mL −1 ) and cucumber (IC 50 :0.10 ng·mL −1 ) samples exhibited ultrahigh sensitivities, with a total analysis time within 15 min. The average recovery rates were 87.2 % ~ 107.4 %, with relative standard deviations of 2.1 % ~ 7.6 % at the spiked levels of 1 and 5 ng·g −1 . Furthermore, this LOC device was applied to unknown food samples, achieving excellent accordance with LC-MS/MS confirmation.
研究领域:
分析化学
·
食品安全
·
环境科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Analytical Methods
·
2024
·
IF 2.7
Yunfeng Bai,Xiaoxuan Fan,Guoning Chen,Zhilong Zhao
Uric acid (UA) level is an important physiological indicator of the human body, which abnormality can lead to a series of diseases. Therefore, the immediate detection of uric acid concentration has broad application prospects. Commonly used methods for the analysis of uric acid include chromatography, high-performance capillary electrophoresis and electrochemical methods. However, these methods have the disadvantages of cumbersome sample pre-treatment, high cost, time-consuming, and the need for experimental instruments and professional operators, which are extremely unfavorable to the detection of uric acid and the diagnosis of related diseases in resource-limited areas. In this study, a portable visualization method was developed for the detection of uric acid by hydrogen peroxide (H2O2) test strips. Uric acid enzyme specifically catalyzes the oxidation of uric acid to produce H2O2, which causes a significant change in the color of the H2O2 test strip. The response has good linearity in the range of 1 ~ 50 μg mL-1. Thus, it provides a simple, rapid, and cost-effective visualized bioassay for uric acid.
研究领域:
生物化学
·
医学诊断
✓ 已验证
产品关联
DOI
PubMed
高影响因子
RSC Advances
·
2025
·Vol. 15
·期 8
·5728-5736
·
IF 4.6
Xintao Xia,Guiyan Yang,Hongwu Tian,Fengjing Cao,Fan Luo,Daming Dong
Nitrate is a primary source of nitrogen pollution in aquatic environments, making timely monitoring of its levels in surface and drinking water essential for environmental protection and public health. Conventional laboratory methods are time-consuming and require specialized expertise, while chemical electrode-based online detection systems are hindered by challenges—such as frequent calibration and ion cross-interference—which limits their suitability for long-term monitoring. To address these limitations, a novel nitrate detection method, utilizing an enhanced Raman spectroscopy device, was developed to rapidly detect nitrate in water. The incorporation of an optical feedback mechanism significantly improved detection sensitivity, achieving a detection limit of 2.89 mg per L N, with single sample analysis completed in under one minute. Furthermore, a compact and portable detection system was designed by integrating the Raman enhancement device with a handheld Raman spectrometer, which was successfully validated using real-world environmental water samples. The proposed nitrate detection system features a streamlined user design and user-friendly operation, offering an innovative approach for rapid water pollution detection and early warning. It also provides a foundation for establishing continuous online monitoring systems for water quality.
研究领域:
环境科学
·
分析化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
TALANTA
·
2025
·
IF 6.1
Xiaofang Liu,Qun Wang,Huan Liu,Yong Zhang,Mei Yang,Danqun Huo,Changjun Hou
Timely detection of breast cancer not only positively influences patient treatment and life quality, but also possesses far-reaching implications for public health and medical research. And miRNAs, as emerging breast cancer-related biomarkers, demonstrate heightened sensitivity to disease progression. In this study, the same precursor was utilized to prepare micromaterials with large and small cavities, this was the safeguard for sensing probes and signals. And the signal amplification process was accomplished with strand displacement assistance by target excitation. Encouragingly, it was successfully and accurately detected miRNA-21 and miRNA-155 within 10 fmol/L - 10 nmol/L. Due to the unique sensing design, the signal can be read out not only by small fluorescent devices, but also by portable glucometers. The biosensor features several excellent working performances and illuminates resource-poor areas by equipping the most common glucometers. So, it is a sensitive, portable and promising biosensor.
研究领域:
分子生物学
·
医学检测
·
生物传感技术
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF CHROMATOGRAPHY A
·
2025
·
IF 4
Liangming Luo,Chenlu Wang,Yong Wu,Hao Zhang,Feng Xu,Keqi Tang,Jiancheng Yu
Screening for illicit drugs in urban wastewater provides an important tool for monitoring and tracing the use of illicit drugs, increasingly leaning towards on-site detection of wastewater samples. This study established an on-site detection method for three illicit drugs—ketamine (KET), cocaine (COC), and codeine(COD)—in wastewater, based on an automatic solid-phase extraction device and a portable mass spectrometer. After enrichment and purification of samples using HLB solid-phase extraction cartridges, a portable mass spectrometer equipped with a sub-atmospheric pressure chemical ionization source was used for quantitative analysis of target drugs in selected ion monitoring mode. The solid-phase extraction conditions and parameters of the subatmospheric pressure chemical ionization source were studied and optimized, and the method was evaluated. The results showed that ketamine, cocaine, and codeine exhibited good linearity (R² > 0.99) within the concentration range of 1∼40 μg/L, with limits of detection (LODs) of 0.30∼0.42 μg/L. The recoveries were between 70.52% and 118.56%. This method can be used for on-site rapid screening of illicit drugs in wastewater. Compared to traditional laboratory analysis methods, it reduces sample transportation and storage costs, shortens the detection cycle. Finally, evaluations based on GAPI, AGREE, and BAGI indicators indicated that this method could serve as a green alternative for the screening of illicit drugs in wastewater.
研究领域:
环境科学
·
分析化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
·
2023
·
IF 4.4
Xiaorong Liu,Zhenzhen Yang,Jing Liu,Wenxiang Xiao,Hua Li
Cholesterol is one of the major markers for cardiovascular diseases. Herein, a portable cholesterol measurement system based on fluorescence color detection was constructed by combining the high sensitivity of fluorescence analysis with the ease of color sensing to determine low levels of serum cholesterol. Cyclodextrin capping gold nanoclusters with blue-green emission were used as fluorescent probes because cholesterol exposure induced fluorescence enhancement of the probe due to the host–guest inclusion interaction between cholesterol and the cavity of cyclodextrin. The integrated sensing system consisted of modules including a microprocessor, a power supply, an LED light with a constant current source, an RGB color sensor, a display, and a darkroom. All the modules except the display screen were placed in a 3D printing darkroom to avoid interference from ambient light. An RGB color sensor TCS230 was applied to capture the RGB signals of the fluorescent color of the probe solution before and after cholesterol addition. Then the obtained RGB signals were converted into the signals in Hue, Saturation, and Value (HSV) color space with a central control chip STM32F407. The Hue value of the fluorescent color of the solution can discriminate the concentration change of cholesterol. Experimental results demonstrate that the system responds linearly to cholesterol in the concentration range of 20.00 ∼ 150.00 μmol·L -1 with a detection limit of 16.07 μmol·L -1 (3 σ , n = 3). The detection of the system has good consistency and accuracy compared with the standard instrument, showing potential for the detection of low levels of serum cholesterol.
研究领域:
生物医学工程
·
分析化学
✓ 已验证
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）