Frontiers in Chemistry
·
2021
·
IF 5.221
Li Ping,Sun Xiang-Ying,Shen Jiang-Shan
In this work, a facile one-pot hydrothermal route was employed to synthesize a series of fluorescent carbon dots (CDs) by using 20 natural amino acids, respectively, as the starting materials. It was found that the CDs synthesized using phenylalanine could possess the intrinsic peroxidase-like activity that could effectively catalyze a traditional peroxidase substrate like 3, 3’, 5, 5’- tetramethylbenzidine (TMB) in the presence of H2O2 to produce a blue solution; thereby, a catalytic sensing system for H2O2 has been developed. On the basis of this catalytic reaction, together with the fact that glucose oxidase (GOx) can catalyze the hydrolysis of glucose to generate H2O2, a sensitive catalytic sensing system for glucose could be further established. Furthermore, based on this catalytic reaction, taken together with the two enzymatic catalytic systems of acetylcholinesterase (AChE) and choline oxidase (CHO), a highly sensitive multi-catalytic sensing system could be successfully developed for organophosphorus (OPs) pesticides such as dimethoate, DDVP, and parathion-methyl. Limit of detections (LODs) of H2O2 and glucose were estimated to be 6.5 and 0.84 μM, respectively. The limit of detection of the sub-nM level could be obtained for tested dimethoate, DDVP, and parathion-methyl OPs pesticides. The established sensing systems can exhibit good practical application performance in serum and several fruit samples.
研究领域:
生物化学
·
分析化学
·
环境科学
✓ 已验证
DOI
PubMed
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2025
·
IF 13.2
Kejun Guo,Lin Zhong,Su Li,Xiya Liu,Junjie He,Linjing Liu,Juan Wang
Electrochemical nanosensors possess high spatiotemporal resolution and easy quantification for single-cell analysis. However, the applied external potential may change the physiological state of cells and cause non-negligible secretion of molecules. Photoelectrochemical analysis not only inherits the merits of electrochemical methods but also with higher sensitivity and can operate without external potential. Nevertheless, the photoelectrode that is typically inserted into samples requires light excitation, leading to the introduction of another stimulus to the cells, which can cause cell membrane depolarization and thus affect cellular electrophysiological signals. We herein report a self-powered photocatalytic sensor based on a photoanode (outside the cell)-cell membrane-cathode (insert the cell) platform with a low detection limit (62 nM) for single-cell H 2 O 2 analysis. The photoanode located extracellularly avoids contact with many reductive small molecules in complex intracellular environments for ensuring highly selective detection of H 2 O 2 , and eliminates light stimulation effects on the inserted single cells. More importantly, the self-powered detection mode refrains from applying external potential, thus significantly reducing electrical stimulation to cells, showing high reliability in single-cell detection. This work provides a powerful tool for single-cell analysis.
研究领域:
生物化学
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分析化学
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纳米科技
✓ 已验证
产品关联
DOI
高影响因子
2D Materials
·
2021
·Vol. 8
·期 3
·035049
·
IF 7.103
Mahsa Jalali,Zhaoli Gao,Ye Yu,Roozbeh Siavash Moakhar,Yao Ding,Minghao Zhuang,Nan Zhou,Tobias König,Andreas Fery,Sara Mahshid,Zhengtang Luo
Enhancing photoluminescence (PL) of semiconducting 2D materials is proven essential for many applications related to optoelectronics and sensing. Here, we demonstrate synergistic PL enhancement in 2D materials by incorporating silver plasmonic nanodiscs in defect-induced monolayer molybdenum disulfide (MoS2) for luminescent quench sensing of dopamine with high accuracy and selectivity. We develop a hole-array perforated 2D MoS2 embedded with plasmonic silver dimers to harmonize the surface plasmon resonance with the PL wavelength of monolayer MoS2, which enhance it by 56-fold. We implemented the optimized perforated MoS2/dimers platform as a catalytic assay for on-chip PL quenching detection of dopamine, achieving a low limit of detection of 9.3 nM. This approach opens avenues of high-performance molecular sensing applications by improving the PL emission of 2D materials.
研究领域:
材料科学
·
光学
·
生物医学工程
✓ 已验证
DOI
高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
·
2019
·
IF 6.393
Tingting Chen,Jinqiong Xu,Pingping Yang,Qinglin Sheng,Jianbin Zheng,Wei Cao,Tianli Yue,Ming Zhou,Chengyue Wang
The paper reported the controlled synthesis of dumbbell-style AuPd and dendrite-like AuPt by a simple seed-mediated growth method, respectively. The composition and performances of the resulting nanomaterials were measured using transmission electron microscopy (TEM), high-resolution TEM (HRTEM), UV–vis absorption spectroscopy (UV–vis), X-ray photoelectron spectroscopy (XPS) and electrochemical methods. Moreover, the dumbbell-style AuPd modified glassy carbon electrode (GCE) showed excellent electrocatalytic ability towards nitrite with a fairly wide concentration range from 2 μM to 4200 μM and a 0.67 μM detection limit. The dendrite-like AuPt modified GCE showed excellent electrocatalytic ability towards tert-butyl hydroquinone (TBHQ) with a linear range from 0.35 μM to 625 μM and a relatively low detection limit of 0.075 μM. The electrochemical testing results exhibited the two kinds of sensors, Au 3 Pd 4 /GCE and Au 3 Pt 3 /GCE, possessed accepted selectivity, long-term stability and good reproducibility. Thus, the proposed two sensors could be applied in the determination of food samples. It is expected that the unique AuPd and AuPt are promising materials, which have great potential application in many fields of clinical diagnosis, new energy technologies, catalysis and sensors.
研究领域:
材料科学
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电化学
·
分析化学
✓ 已验证
产品关联
DOI
高影响因子
Journal of Materials Chemistry C
·
2018
·Vol. 6
·期 30
·8105-8114
·
IF 5.976
Ping Gao,Xiang-Ying Sun,Bin Liu,Hui-Ting Lian,Xin-Qiang Liu,Jiang-Shan Shen
Developing a catalyst with a uniform and well-defined crystal structure is very important to establish a catalytic sensing system with high efficiency. In this work, Cu-BTC metal–organic frameworks (MOFs) without a crystalline CuO or Cu2O phase were successfully synthesized by using a low temperature synthesis method, and the as-prepared Cu-BTC MOFs were found to have outstanding catalytic activity towards the traditional oxidase substrate, o-phenylenediamine (OPD), to generate a colored and fluorescent product. The results of the kinetics analysis revealed that the catalytic behavior of Cu-BTC MOFs towards OPD could well follow the typical Michaelis–Menten equation, indicative of a strong affinity between Cu-BTC MOFs and OPD. On the basis of these findings, taken together the condensation reaction between the –CHO group of formaldehyde and the –NH2 group of OPD to form Schiff base compounds, a novel Cu-BTC MOF-based catalytic sensing system for detecting gaseous formaldehyde could be successfully established.
研究领域:
催化
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材料科学
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分析化学
✓ 已验证
产品关联
DOI
高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
·
2017
·
IF 5.401
Zheng-Nan Wei,Xiao-Xia Yang,Zhi-Hong Mo,Feng Leng
Photocatalytic oxidation of organics in water is imperative to exploit for environmental analysis due to its green and low-cost advantages. Driven by the visible light, metal nanoparticles exhibit local surface plasmons (so called nanoplasmons), providing a simple and sensitive optical transduction of the electron density surrounding the particles, in addition to enhancing the photocatalytic activity. Thereof, a novel photocatalytic sensor for the detection of organics was proposed using a nanocomposite film consisting of gold and titania nanoparticles and fullerene (Au-TiO 2 -C 60 ), where gold nanoparticles were introduced as both the co-catalyst and the plasmonic sensor. In the redox reaction, the repeated shifts of the nanoplasmonic peak of gold nanoparticles, as a result of the electron transfer mediated by gold nanoparticles, was observed using surface plasmon spectroscopy. The frequency of the plasmonic swing reflects the reaction rate and was used to determine the concentration of organics in water. A response background close to zero provides the sensor with a high precision and a high sensitivity, offering a great potential of the plasmonic sensor in practical applications.
研究领域:
环境科学
·
纳米技术
·
光学传感
✓ 已验证
产品关联
DOI
高影响因子
NEW JOURNAL OF CHEMISTRY
·
2022
·Vol. 46
·期 34
·16341-16351
·
IF 3.925
Wanjun Jiang,Shiyu Wu,Guorong Fan,Zongde Wang,Shangxing Chen,Yangping Wen,Peng Wang
The extraordinary properties and unique structure of porous carbon have rapidly turned it into a new favorite in the development and application of high-performance electrocatalytic sensors. Nitrogen, phosphorus co-doped hollow porous carbon microspheres (PRM-HPAs) as an oxidase-like electrocatalytic sensor for baicalin were successfully developed by two-stage activation using both 3-aminophenol and formaldehyde as carbon sources, phosphoric acid as an activator and dopant, and N-dehydroabietoyl-L-alanine as a soft-template. Low-temperature activation in air is the key to obtaining the hollow structure, and increases the content of oxygen-containing groups. High-temperature activation with phosphoric acid in nitrogen significantly increases the micropore content of PRM-HPA, and realizes phosphorus doping. The introduction of a soft-template can effectively prevent the agglomeration of carbon particles, and form uniformly dispersed hollow carbon microspheres. The PRM-HPA with a specific surface area of 1388 m2 g−1, pore volume of 0.69 m3 g−1, and pore size of 17 Å displays excellent electrocatalytic ability, oxidase-like characteristics, and an excellent electrochemical response of about 118-fold enhancement for baicalin in linear ranges of 0.03–7.99 μM with a low limit of detection of 4.3 nM. This work will open a new pathway for the preparation of co-doped hollow porous carbon microspheres and the application of renewable rosin resource.
研究领域:
材料科学
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分析化学
·
药物分析
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF MATERIALS SCIENCE
·
2020
·Vol. 56
·期 7
·4666-4676
·
IF 3.553
Wang Pan,Tian Xuemin,Yan Meng,Yang Boxuan,Hua Zhongqiu
In this study, a catalytic-type combustible gas sensor was fabricated by the screen-printing method. Pt supported catalysts (Pt-HZSM5) were prepared by a wet impregnation method using HZSM5 zeolite as support. It was found that Pt-HZSM5 catalysts have a highly catalytic activity to H 2 and CO at low temperatures and a selectively and fully combustible was observed at only 150 °C. A good dispersion state of Pt nanoparticles on HZSM5 zeolite particles was beneficial for the catalytic oxidization of CO and H 2 . However, a high loading amounts lead to a poor dispersion state and a weak catalytic activity. The thick film sensor based on Pt-HZSM5 catalyst was found to be highly sensitive to combustible gas with a good linearity up to 2% and a limitation of detection (LOD) around 50 ppm. Due to the low operation temperature, a highly selectivity was obtained for CO and H 2 and no cross-sensitivity to interfering gases such as CH 4 and VOCs. It was indicated that the present developed catalytic-type gas sensors could be used for the leakage detection and monitor for H 2 and CO with a low power consumption and a good selectivity.
研究领域:
材料科学
·
化学工程
·
传感器技术
✓ 已验证
DOI
高影响因子
JOURNAL OF ALLOYS AND COMPOUNDS
·
2025
·
IF 6.3
Yuan Li,Shaoqian Jia,Ling-Xin Kong,Xiaotian Guo,Xinyi Lin,Dae Joon Kang,Huan Pang,Feng Yu
Accurate detection of nitrite plays a vital role in public health because excessive intake poses serious health risks. Metal-organic frameworks (MOFs) and their derivatives have emerged as a promising platforms for nitrite detection due to their adjustable structures and functionalization capabilities. In this study, we synthesized Ag/Cu-BTC by doping silver ions during Cu-BTC synthesis, followed by high-temperature carbonization to produce carbon-supported Ag-Cu bimetallic nanoparticles (Ag/Cu@C) for effective nitrite sensing. The carbon framework from MOF precursors not only enhances electrical conductivity and stability but also prevents nanoparticle aggregation. Silver addition enhances electron transfer efficiency and alters the electronic structure through synergistic interactions with copper, resulting in increased catalytic activity. The optimized Ag/Cu@C composite shows excellent sensing performance with a detection limit of 50 nM, high sensitivity (855.32 μA mM −1 cm −2 ), and a wide linear response range (0.2–10,000 μM). The sensor maintains 98.5–103.2 % recovery against 10-fold concentrations of common interferents (Cl - , NO 3 - , SO 4 2- , glucose), and retains 92.3 % initial current after 28 days, demonstrating exceptional selectivity and operational stability. These features highlight its significant potential for practical applications in environmental monitoring and food safety testing.
研究领域:
电化学传感
·
纳米材料
·
金属有机框架（MOFs）
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环境监测
·
食品安全
✓ 已验证
产品关联
DOI
高影响因子
ANALYTICA CHIMICA ACTA
·
2022
·
IF 6.911
Xuekun Bai,Zhengzheng Wang,Weiqiang Li,Fangbin Xiao,Hengyi Xu
Listeria monocytogenes ( L. monocytogenes ), a typical foodborne pathogen , poses a serious threat to public health safety. This stimulates to develop a point-of-care testing (POCT) method to achieve rapid, sensitive detection of L. monocytogenes . In this study, polyethylene glycol (PEG) mediated ampicillin functionalized magnetic beads (Amp-PEG-MBs) was prepared successfully and it achieved high efficiency (>90%) and rapid (5 min) capture for L. monocytogenes at room temperature . The innovative combination of antibody (Ab), glucose oxidase (GOD) and graphene oxide (GO) prepared [email protected] @GOD for the specific recognition of L. monocytogenes . Finally, Amp-PEG-MBs and [email protected] @GOD were successfully assembled into [email protected] L. monocytogenes [email protected] @GOD sandwich structure which could catalyze the glucose, and the final detection results were recorded by a blood glucose meter (BGM). Magnetic separation (MS) combined with enzyme-catalyzed sensor ( [email protected] @GOD-BGM) was successfully established to achieve the detection of L. monocytogenes in artificially contaminated juice within 66 min with the limit of detection was 10 1 CFU/mL. This sensor has potential for other pathogens detection by modifying specific antibodies.
研究领域:
食品科学
·
生物技术
·
分析化学
·
即时检测
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Analytical Methods
·
2019
·Vol. 11
·期 43
·5613-5622
·
IF 2.378
Xiaojiao Wang,Yang Li,Yuanzhen Zhou,Yijia He
Bisphenol A (BPA) is one of the most prevalent environmental endocrine disrupting chemicals. In this present paper, a facile BPA sensor was successfully fabricated based on a La-doped Yb2O3 nanorod modified carbon paste electrode (La–Yb2O3/CPE). La-doped Yb2O3 nanorods were synthesized using a one step hydrothermal synthesis method and further investigated by X-ray diffraction (XRD), scanning electron microscopy (SEM) and energy dispersive X-ray spectroscopy (EDS). Electrochemical impedance spectroscopy (EIS), cyclic voltammetry (CV) and amperometric response analysis were applied to characterize the electrochemical properties of the sensor. Under the optimal conditions, the oxidation current increased linearly with increasing the concentration of BPA in the range of 0.04 to 15 μM with a detection limit of 0.013 μM. The prepared La-doped Yb2O3 nanomaterial modified electrode showed good reproducibility, stability and anti-interference ability. Furthermore, this newly developed sensor was further adopted to measure BPA in tap water and milk samples. The possible electrocatalytic sensing mechanism is discussed.
研究领域:
环境科学
·
分析化学
·
纳米技术
·
电化学
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）