MICROCHEMICAL JOURNAL
·
2024
·
IF 4.9
Yizhi Zhou,Qiang Liu
The sensitive and label-free detection of microRNA (miRNA) is crucial for the comprehension of miRNA-related pathological process, such as glioma. Here, we utilized a SYBR Green I (SG) catalytic photosensitization colorimetric reaction in conjunction with target recognition-induced exonuclease-iii (Exo-iii) assisted cascade toehold assembly amplification to achieve highly sensitive and label-free miRNA detection. In this research, the photosensitized generation of 1 O 2 by SG could directly oxidize 3,3′,5,5′-tetramethylbenzidine (TMB) without the need for H 2 O 2 oxidation or enzyme catalysis, which simplifies the experimental procedures and renders the method highly stable. Furthermore, the Exo-iii enhances the target recognition induced catalytic chain assembly, thereby forming cascade signal amplification and providing the method with a significantly higher level of sensitivity than conventional colorimetric miRNA detection methods. Based on this, the proposed method exhibits a low limit of detection of 2.1 fM for miRNA-212 detection. Taking the merit of the high sensitivity, portability, and simplicity, the proposed method can serve as a highly effective nucleic acid detection tool and can facilitate the advancement of biosensors for point-of-care testing (POCT) and clinical disease diagnosis.
研究领域:
生物化学
·
分子诊断
·
医学检测
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产品关联
DOI
高影响因子
WATER RESEARCH
·
2025
·
IF 12.4
Jianqiao Xu,Xinyuan Wei,Junyan Wei,Mengqiang He,Xiaolei Teng,Zunyao Wang,Ruijuan Qu
While the reaction mechanism of direct photochemical dechlorination has been extensively studied, significant knowledge gaps remain regarding the specific roles of reactive species in governing dechlorination pathways during indirect photodegradation. By integrating mass spectrometry analysis, probe experiments and theoretical calculations, we propose for the first time an indirect dechlorination reaction mechanism for PCB-209 involving active species commonly found in DOM photosensitive systems, which differs significantly from that of direct photodegradation. Due to the lower bond energy of the C Cl bond at the position opposite the carbon bridge, PCB-209 primarily yielded PCB-208 in direct dechlorination systems. However, our study revealed that active species ( 3 DOM*, •O 2 − and 1 O 2 ) can specifically weaken the meta-positioned C Cl bond at the carbon bridge through electron transfer and cycloaddition mechanisms, thereby fundamentally altering the regioselectivity of dechlorination. Remarkably, our results confirm the indirect degradation of PCB-209 through DOM photosensitization to form dechlorination products dominated by PCB-207, a previously unrecognized transformation pathway in natural photochemical processes. This study refines the mechanism of indirect dechlorination mediated by reactive species and provides a predictive framework for the environmental fate of halogenated pollutants in real complex environmental systems.
研究领域:
环境科学
·
化学
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产品关联
DOI
PubMed
高影响因子
ACS Sustainable Chemistry & Engineering
·
2015
·
IF 4.642
Fang Xu,Xiang-Ning Song,Guo-Ping Sheng,Hong-Wei Luo,Wen-Wei Li,Ri-Sheng Yao,Han-Qing Yu
The generation of hydroxyl radical (•OH) under solar irradiation from natural photosensitizers is widely recognized to play a key role in the photochemical degradation of biorefractory organic pollutants. Solar-light-mediated •OH production has been supposed as a green and sustainable strategy in water and wastewater treatment. In this study, an efficient visible-light-mediated •OH generation method using the photosensitization of vitamin B2 (VB2) catalyzed by dissolved iron was proposed. •OH generation was validated by electron paramagnetic resonance spectroscopy combined with spin trapping, and was further confirmed using the hydroxylation of nitrobenzene. VB2 plays a dual role of in the process of •OH generation. In the initial step, VB2 works as an excellent photosensitizer. Upon absorption of a photon, VB2 gives rise to its excited singlet state (1VB*) and, through intersystem crossing, to its excited triplet state (3VB*). In the subsequent step, VB2 works as an effective electron mediator to mediate O2•– generation. However, O2•– is sensitive to proton and is converted to H2O2 quickly in water. Ultimately, the •OH generation occurs through dissolved-iron catalyzed decomposition of H2O2. All ingredients involved in this process are nontoxic, environmentally benign, and easily available. Thus, this process might have potential environmental implications.
研究领域:
环境科学
·
化学
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产品关联
DOI
高影响因子
Energy & Environmental Science
·
2017
·Vol. 10
·期 3
·772-779
·
IF 29.518
Kai-Hang Ye,Zilong Wang,Jiuwang Gu,Shuang Xiao,Yufei Yuan,Yi Zhu,Yuanming Zhang,Wenjie Mai,Shihe Yang
Here, we demonstrate that carbon quantum dots (CQDs), as a low cost, chemically stable, and environmentally friendly photosensitizer, can dramatically broaden the light absorption range to the entire visible range. Consequently, the NiOOH/FeOOH/CQD/BiVO4 (NFCB) photoanode has achieved a remarkable photocurrent density of 5.99 mA cm−2 at 1.23 V vs. RHE under AM 1.5G in KH2PO4 aqueous solution without a hole scavenger (pH = 7) and a record high applied bias photon-to-current efficiency of 2.29% at 0.6 V vs. RHE for BiVO4-based photoanodes. This novel NFCB photoanode could operate stably for 10 h with a Faraday efficiency of ∼95%, demonstrating the great potential of using CQDs for solar water splitting.
研究领域:
材料科学
·
可再生能源
·
环境科学
✓ 已验证
DOI
高影响因子
Chemical Engineering and Processing-Process Intensification
·
2025
·
IF 3.9
Juxiang Chen,Sitong Lin,Chong Ruan,Lin Liu,Shangye Yang
The proliferation of sulfonamide antibiotics (SAs) in aquatic ecosystems poses a severe threat to environmental integrity and human well-being. This research employs an acclimation strategy using Chlorella pyrenoidosas to enhance the photo-sensitized degradation efficacy of sulfamethoxazole (SMX) and sulfisoxazole (SIZ). The acclimated Chlorella exhibits remarkable degradation capabilities, with improvements of approximately 9.7 times for SMX and 4.2 times for SIZ, respectively, compared to non-acclimated strains. These improvements are linked to increased growth rates, higher chlorophyll levels, enhanced extracellular organic matter (EOM) production, and elevated antioxidant enzyme activities. The enhanced performance is attributed to refined enzymatic and metabolic processes promoting photosynthesis, energy conversion, and the degradation of SAs. Through response surface methodology, this approach is refined to achieve optimal water remediation results, attaining a degradation rate of 78.04 %. The EOM content increases by up to 68.33 %, while growth rates improve by 1.06 to 1.14 times, indicating superior tolerance. A biphasic response to antibiotic concentrations is also observed, where low concentrations facilitate degradation while high concentrations have an inhibitory effect. This characteristic is reflected by significant increases in antioxidant enzyme activities, particularly in the case of glutathione reductase (GR) and catalase (CAT) at concentrations below 1 mg/L.
研究领域:
环境科学
·
微生物学
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产品关联
DOI
高影响因子
MOLECULES
·
2023
·Vol. 28
·期 10
·4237
·
IF 4.6
Zhiyao Zhang,Zhaolin Li,Xue Bai,Juan Shi,Min Hu,Jin Chai,Keqian Li,Pengkang Jin
Commonly used peroxydisulfate (PS) or peroxymonosulfate (PMS) activation methods have been limited in their practical application due to certain drawbacks, such as high cost, high energy consumption and secondary pollution. In this study, a catalyst-free alizarin green (AG) self-activating PMS catalytic system was constructed based on photosensitization properties of dye, which ultimately achieved efficient degradation of the dye activator, also the target pollutant. Here, 52.5% of the 100 mL mixture of 10 mg/L AG decomposed within 60 min with 1 mM PMS under visible-light irradiation, thereby showing a strong pH adaptation. Mechanism of AG self-activating PMS was revealed that the photo-excited AG can effectively transfer photo-induced electrons to PMS for its activation, which generates reactive oxidizing species dominated by singlet oxygen (1O2), and supplemented by hydroxyl radical (•OH), superoxide radical (O2•−) and sulfate radical (SO4•−) to realize the efficient self-degradation of the dye pollutants. Moreover, such self-catalytic system operated well under natural sunlight irradiation, indicating the great application potential in the actual wastewater treatment. Herein, photosensitive dye acted as an ideal PMS activator realizing its efficient self-degradation, which provides a novel idea of “using waste to treat waste” for developing wastewater treatment process in a high-efficiency and low-consumption way.Keywords:alizarin green dye;photosensitization;PMS;catalysis;using waste to treat waste
研究领域:
环境科学
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化学工程
·
废水处理
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产品关联
DOI
PubMed
高影响因子
Science China-Chemistry
·
2013
·Vol. 57
·期 2
·243-247
·
IF 1.327
Zhang XuePeng,Zhang GuoQing
Poly(ethylene glycol)-modified β-diketone macroligand is developed to sensitize europium(III) ions in water. High luminescence intensity characteristic of Eu 3+ was achieved due to spontaneous formation of micelle-like structure in which the hydrophobic core prevents luminescence-quenching by water molecules. The pH is found to induce a quantitative ratio change in two fluorescence bands from both ligand and Eu 3+ .
研究领域:
化学
·
材料科学
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DOI
高影响因子
WATER RESEARCH
·
2021
·
IF 11.236
Jiaxin Lu,Yuefei Ji,Jean-Marc Chovelon,Junhe Lu
Fluoroquinolone (FQ) antibiotics are a group of contaminants of emerging environmental concern. In the present study, we demonstrated that norfloxacin (NORF) and ofloxacin (OFLO), two typical FQs, have photochemical reactivity analogous to chromophoric dissolved natural organic matter (DOM) in surface waters and can sensitize the photodegradation of isoproturon (IPU), a phenylurea herbicide. Such photochemical reactivity is ascribed to the quinolone chromophore that is excited to a triplet state ( 3 FQ*) upon UV-A irradiation. 3 FQ* further reacts with dissolved oxygen to give rise to singlet oxygen. 3 FQ* steady-state concentrations of 6.72 × 10 −15 and 1.27 × 10 −15 M were measured in 10 μM NORF and OFLO solutions, respectively, under UV 365nm irradiation. The degradation of IPU was due to the reaction with 3 FQ*, with bimolecular rate constants of 6.07 × 10 9 and 1.51 × 10 10 for 3 NORF* and 3 OFLO*, respectively. Intriguingly, NORF and OFLO per se were unstable and photolyzed during UV-A irradiation, but the photochemical reactivities of the solutions were not lost accordingly. High-resolution mass spectrometry analysis revealed that defluorination and piperazine moiety oxidation were the main photolysis pathways, while the core quinolone structure remained intact. Thus, the photolysis products largely inherited the photochemical reactivity of the parent compounds. Since all FQs share the same quinolone structure, similar photochemical reactivity is expected. The presence of FQs in surface water would affect the transformation and fate of coexisting compounds. To the best of our knowledge, this is the first study examining the environmental behavior of FQs as photosensitizers. The findings greatly advance the understandings of the influence of FQs in aquatic environment.
研究领域:
环境科学
·
化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2012
·
IF 3.07
Yan-Jing Gu,Bing Yan
A series of new visible and near-infrared (NIR) luminescent lanthanide-hydroxybenz[de]anthracen derivatives (Ln(HBAN) 3 (H 2 O) 2 (NO 3 ) 3 , Ln(HBAN) 3 phen(NO 3 ) 3 ) were synthesized (HBAN-6-hydroxybenz[de]anthracen-7-one, Ln = Eu, Yb, Nd). Further, chemically bonded lanthanide hybrids of functionalized mesoporous silica (SBA-15) are prepared using HBAN-functionalized alkoxysilane (HBAN-Si) as linker, which is named as Ln(HBAN-SBA-15) 3 (NO 3 ) 3 , Ln(HBAN-SBA-15) 3 phen(NO 3 ) 3 (Ln = Eu, Yb, Nd), respectively. The physical characterization and especially the photoluminescence properties for these hybrids are performed. SAXRD and BET of them revealed that all of these hybrid materials have uniformity in the mesostructure. Worth noting here is that the excitation spectra of these hybrid materials are extended to visible light region (439–535 nm). Upon ligand-mediated excitation with the ultraviolet and visible light, the visible luminescence for europium hybrids and NIR luminescence for Yb 3+ and Nd 3+ hybrids are obtained.
研究领域:
材料科学
·
光学
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产品关联
DOI
PubMed
高影响因子
NEW JOURNAL OF CHEMISTRY
·
2014
·Vol. 39
·期 2
·1274-1280
·
IF 3.159
Fan Tian,Yafang Zhang,Guangfang Li,Yunling Liu,Rong Chen
Bismuth oxychloride (BiOCl) nanosheets with tunable thickness were synthesized via a facile solvothermal method. The obtained BiOCl products were characterized by powder X-ray diffraction (XRD), scanning electron microscopy (SEM), transmission electron microscopy (TEM) and nitrogen adsorption. It was found that the metal ions (Fe3+, Co2+ and Na+) played a significant role in modulating the thickness of two-dimensional (2D) BiOCl nanostructures. Compared with commercial P25 and commercial BiOCl, the as-prepared BiOCl nanosheets exhibited superior activity for photosensitization degradation of organic dyes upon visible light irradiation. Furthermore, the photosensitization degradation activities were strongly correlated with the thickness of BiOCl nanosheets. The thinner nanosheets demonstrated a relatively high activity for the degradation of Rhodamine B (RhB). The enhanced photosensitization activities were ascribed to its low electron injection barrier and high electron mobility on the surface of BiOCl nanosheets, which was confirmed by transient photocurrent responses and electron impedance spectra of the samples.
研究领域:
材料科学
·
环境科学
·
光催化
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产品关联
DOI
高影响因子
SYNTHETIC METALS
·
2017
·
IF 2.435
Peng Kong,Rui Wang,Chen Zhang,Zhongjie Du,Hangquan Li,Wei Zou
A novel strategy for synthesizing a quantum dot (QD)-sensitized silver nanowire (AgNW) nanocomposite has been reported. 4-aminothiophenol (PATP) functionalized quantum dots (QDs-PATP) were prepared using the thiol ( SH) end of PATP molecules strongly bound to the surface of QDs via a ligand exchange technique. AgNWs could bind to the remaining amino group ( NH 2 ) of PATP via self-assembly techniques, and quantum dot-sensitized silver nanowires were then formed. The nanocomposite is denoted as QDs-PATP@AgNWs. The photovoltaic properties of a quantum dot-sensitized solar cell (QDSSC) based on QDs-PATP@AgNWs were investigated. Under AM 1.5 illumination, the QDSSC reached a peak conversion efficiency of 3.34%. This finding suggests that QDs-PATP@AgNWs had potential applications as a photoanode for QDSSC.
研究领域:
材料科学
·
纳米技术
·
能源科学
✓ 已验证
产品关联
DOI
高影响因子
ANALYTICAL CHEMISTRY
·
2023
·
IF 7.4
Yu Zheng,Xinyi Li,Caixia Wei,Yawen Gao,Guangmei Han,Jun Zhao,Cheng Zhang,Kui Zhang,Zhongping Zhang
Free radicals and their induced oxidative damage in living organisms are related to many diseases. Natural substances with antioxidant capacity are effective in scavenging free radicals, which could slow down aging and prevent diseases. However, the existing methods for the evaluation of antioxidant activity mostly required the use of complex instruments and operations. In this work, we proposed a unique method to determine the total antioxidant capacity (TAC) in real samples through a photosensitization-mediated oxidation system. N- and P-doped long-lived phosphorescent carbon dots (NPCDs) were developed, which exhibited the effective intersystem crossing from the singlet to the triplet state under UV light irradiation. Mechanism study confirmed that the energy of excited triplet state in NPCDs generated superoxide radicals and singlet oxygen through type I and type II photoreactions, respectively. On this basis, the quantitative determination of TAC in fresh fruits was achieved using 3,3′,5,5′-tetramethylbenzidine (TMB) as a chromogenic bridge in the photosensitization-mediated oxidation system. This demonstration will not only provide a facile way to analyze antioxidant capacity in practical samples but also broaden the applications of phosphorescent carbon dots.
研究领域:
生物化学
·
分析化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）