ANALYTICA CHIMICA ACTA
·
2020
·
IF 5.977
Shuhuai Li,Xionghui Ma,Chaohai Pang,Haibo Li,Chunhua Liu,Zhi Xu,Jinhui Luo,Yan Yang
The use of dual recognition and multiple detection modes is an attractive strategy for realising sensors with improved selectivity and accuracy. Herein, a molecularly imprinted polymer (MIP)-based sensor is developed for amoxicillin detection based on two detection modes (fluorescence and electrochemiluminescence) and dual recognition. First, graphene oxide loaded with CdTe quantum dots/gold nanoparticles (GO/CdTe/Au NPs) is coated onto an indium tin oxide (ITO) electrode. Then, 4-mercapto-calix[6]arene is bonded to GO/CdTe/Au NPs as the first recognition element, which then form a host–guest complex with the target molecule amoxicillin. Subsequently, as the second recognition element, an MIP is prepared on the ITO electrode. After amoxicillin is removed from the MIP, specific identification sites for amoxicillin are obtained. Furthermore, the GO/CdTe/Au NPs can generate fluorescence and electrochemiluminescence signals that are effectively quenched by amoxicillin. Therefore, on/off switching of these signals can be achieved through the elution or adsorption of amoxicillin. The dual detection modes are complementary and provide mutual authentication, which can improve the detection accuracy and application scope. Moreover, the dual recognition sites for amoxicillin, improve detection selectivity. The fluorescence and electrochemiluminescence modes have detection ranges of 5–1000 × 10 −11 mol L −1 and 5–1500 × 10 −11 mol L −1 , respectively, with detection limits of 9.2 × 10 −12 mol L −1 and 8.3 × 10 −12 mol L −1 , respectively.
研究领域:
分析化学
·
生物传感技术
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DOI
高影响因子
CRYSTENGCOMM
·
2023
·Vol. 25
·期 8
·1232-1239
·
IF 3.1
Gui-Mei Huang,Shuang Li,Meng-Xia Ma,Shi-Ming Li,Wen-Qiang Li,Qing-Ling Ni,Liu-Cheng Gui,Xiu-Jian Wang
Four MOFs with mixed ligands, [Zn3(3-BABA)2(bpa)2(H2O)2]n (1), [Cd3(3-BABA)2(bpa)2]n (2), [Cd3(3-BABA)2(bpe)2]n (3), and {[Cd3(3-BABA)2(bib)(DMA)2]·H2O}n (4) (where 3-H3BABA = 4′,4′′′-(((2-carboxyphenyl)azanediyl)bis(methylene))bis(([1,1′-biphenyl]-2-carboxylic acid)), bpa = 4,4′-azopyridine, bpe = 1,2-bis(pyridin-4-yl)ethane, and bib = 1,4-bis(imidazole)butane), have been synthesized. They are characterized by single crystal X-ray diffraction, X-ray powder diffraction (XRPD), thermogravimetric analysis (TGA) and Fourier transform infrared (FT-IR) spectroscopy. In 1, two 3-BABA and two bpa bridge three Zn2+ ions to form a bicyclic [Zn3(3-BABA)2(bpa)2] unit which is further bridged by carboxylate groups with its adjacent units, resulting in a one-dimensional chain. In 2, 3 and 4, the [Cd3(CO2)6] units are bridged by six 3-BABA ligands into a three-dimensional structure. However, the adjacent [Cd3(CO2)6] units in 2 and 3 are doubly-bridged simultaneously by corresponding pyridyl ligands, while the adjacent [Cd3(CO2)6] units in 4 are singly-bridged simultaneously by corresponding pyridyl ligands. The luminescence sensing investigation indicates that compound 1 exhibits extremely sensitive and selective detection of Cu2+ with a detection limit of 0.363 μM, and compounds 2–4 show extremely sensitive and selective detection of Fe3+ with detection limits of 0.539 μM, 0.265 μM, and 0.748 μM, respectively. Competitive experiments in the presence of interfering cations with 1–4 revealed no major change in the quenching efficiency.
研究领域:
化学
·
材料科学
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DOI
高影响因子
Current Analytical Chemistry
·
2025
·Vol. 21
·期 1
·57-67
·
IF 1.7
Mengfei Yang,Jing Shi,Taiming Luo,Xiaozhan Yang
Aims By using terephthalic acid, 2, 5-furandicarboxylic acid, and terbium nitrate hexahydrate, a Tb-MOF with a core-shell structure was successfully designed and prepared. Methods A one-pot method was employed to design and synthesize core-shell Tb-MOF. The morphology, luminescence performance, and stability were well characterized. Results Tb-MOF demonstrated good water stability, acid and alkali resistance, and thermal stability. Tb-MOF was found to have high sensitivity to detect Cr3+, Bi3+, and acetone in an aqueous solution, and the LOD of Cr3+, Bi3+, and acetone were calculated to be 0.18 μM, 4.22 μM, and 0.26%, respectively. The sensing mechanism of Cr3+ and acetone was explained as energy-competitive absorption, and the sensing mechanism of Bi3+ was explained as ion replacement. Conclusion The prepared Tb-MOF can be developed as a multifunctional light-emitting sensor with high selectivity.
研究领域:
材料科学
·
分析化学
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产品关联
DOI
高影响因子
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
·
2019
·
IF 2.931
Xinyi Wang,Zhu Su,Liang Li,Yifeng Tu,Jilin Yan
Molybdenum (Mo) is an essential nutrient for the proper functioning of some enzymes in living organisms as human beings. Conventional methods for its detection require complicated instrumentations as atomic absorption or mass spectrometers. In this work, a sensitive kinetic fluorescence was developed as an alternative. Gold nanoclusters (AuNCs) with red fluorescence emission were synthesized, and this fluorescence was effectively quenched by iodine through an etching process. It was found that the presence of Mo significantly speeded up a reaction for the generation of iodine, and thus enhanced the quenching. This effect was then adopted for the development of a sensitive fluorescent measurement toward Mo. The method was capable of detecting Mo down to 0.2 nM and was successfully applied for the analyses of mung bean and tea leaf samples.
研究领域:
分析化学
·
生物化学
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产品关联
DOI
PubMed
高影响因子
FOOD CHEMISTRY
·
2022
·
IF 9.231
Xiaoyu Zhang,Qinqin Ma,Xinfang Liu,Huawei Niu,Lei Luo,Rongfang Li,Xun Feng
A new europium metal–organic framework ( Eu-MOF ) was prepared by simple hydrothermal method . The product exhibited intense red fluorescence, long fluorescence lifetime (0.454 ms) and excellent fluorescence stability. The fluorescence titration result showed that Fe 3+ could completely quench the fluorescence of Eu-MOF , while the fluorescence quenching effect of Fe 2+ or bromate was negligible. Considering the strong oxidizing property of bromate, a “turn off” Eu-MOF@Fe 2+ sensor toward bromate was designed by generating Fe 3+ due to the redox reaction . The results showed that the sensor displayed a wide linear range (0–0.2 mM), high sensitivity (LOD = 3.7 × 10 −6 mol/L), good selectivity and resistant to possible interferences in real four sample. Furthermore, the detection mechanism was investigated by PXRD, XPS and UV–Vis methods. More importantly, the Eu-MOF@Fe 2+ sensor was further applied to detect bromate in wheat flour with satisfactory recovery (95.30%−104.38%) and accuracy (RSD < 2.85%). These results suggest that Eu-MOF@Fe 2+ can be used as a potential sensor to detect bromate in food industry.
研究领域:
分析化学
·
食品安全
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DOI
高影响因子
MICROCHIMICA ACTA
·
2017
·Vol. 185
·期 1
·1-8
·
IF 4.58
Wang Jing,Peng Xiao,Li Daquan,Jiang Xiaochun,Pan Zaifa,Chen Aimin,Huang Liang,Hu Jun
A dually emitting quantum dot nanohybrid was designed for the fluorometric 2-wavelength determination of ascorbic acid (AA). The nanohybrid consists of red-emitting CdTe quantum dots (QDs) covalently linked to the surface of silica nanoparticles containing green-emitting CdSe QDs. The fluorescence of the red-emitting CdTe QDs (peaking at 616 nm) is first quenched by addition of KMnO 4 due to oxidation under formation of CdTeO 3 and TeO 2 . On addition of AA, the red fluorescence is restored due to the reduction of surface CdTeO 3 /TeO 2 to form CdTe. The green fluorescence of the green-emitting CdSe QDs (peaking at 522 nm), in contrast, remains constant and its intensity serves as a reference signal. Both kinds of QDs can be photoexcited at 380 nm. An easily distinguishable transition in fluorescence (from green to orange-red) can be observed on increasing the amount of added AA. Under optimal conditions, the ratio of the intensities of the red and the green fluorescence increases linearly in the 0.1 to 5.0 μM AA concentration range, and the detection limit is as low as 35 nM. The assay was successfully applied to the quantitation of AA in (spiked) fruit juice samples.
A new dually emitting CdSe@SiO 2 @CdTe nanohybrid was designed for ratiometric ultrasensitive fluorometric detection of ascorbic acid in fruit juice samples.
研究领域:
分析化学
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纳米技术
·
食品科学
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产品关联
DOI
PubMed
高影响因子
Food Analytical Methods
·
2014
·Vol. 8
·期 2
·428-437
·
IF 1.802
Zeng Fang,Ou Jun,Huang Yufen,Li Qian,Xu Guizhi,Liu Zhongzhen,Yang Shaohai
The present paper reports the application of an optimized pre-column derivatization procedure with aminoquinolyl- N -hydroxysuccinimidyl carbamate (AQC) to the determination of 21 free amino acids in fruit juices. The method permitted the optimal separation of 21 amino acids and ammonium in 30 min. Excellent response linearity was obtained from 2 to 1,000 μM for all amino acids, except tryptophan, for which the linearity was 5–1,000 μM. The fluorescence detection limits ranged from 0.08 pmol (phenylalanine) to 0.69 pmol (cysteine), except for tryptophan (7.89 pmol), for a signal-to-noise ratio of 3. The relative standard deviations of peak areas ranged from 0.1 to 0.4 % for intraday analysis and from 2.1 to 5.0 % for interday analysis. The method was applied to analyze the free amino acids in six fruit juices, and the recoveries of the proposed method were 90.4 to 103.3 %. The total free amino acid content ranged from 56.97 mg L −1 (apple) to 469.45 mg L −1 (longan) in six fruit juices. Aspartic acid (Asp), glutamic acid (Glu), asparagine (Asn), serine (Ser), and glutamine (Gln) were present in higher levels in most samples, whereas cysteine (Cys) was below the detection limit in the selected samples. Notable advantages of this method include its speed, ease, low cost, good repeatability, high sensitivity, excellent precision and accuracy, and anti-interference in high-sugar matrices.
研究领域:
食品科学
·
分析化学
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产品关联
DOI
高影响因子
MICROCHEMICAL JOURNAL
·
2020
·
IF 3.594
Yong Li,Xuan Li,Hongliang Tan,Zhen-Zheng Huang
In this work, a turn-on fluorescent assay based on carbon dots/manganese dioxide nanosheet (CDs/MnO 2 ) assembly was developed for the detection of glucose. The fluorescence of CDs was first quenched by the addition of MnO 2 nanosheet to form CDs/MnO 2 assembly, which leads to a fluorescence resonance energy transfer (FRET) process from CDs to MnO 2 nanosheet. When H 2 O 2 was introduced into the quenched CDs solution, the MnO 2 nanosheet was destroyed due to the redox reaction between H 2 O 2 and MnO 2 nanosheet, and the fluorescence of CDs was recovered accordingly. On this basis, by coupling with the oxidation reaction of glucose catalyzed by glucose oxidase, which produces gluconic acid and H 2 O 2 , a fluorescent assay for the quantitative analysis of glucose can be proposed. Under optimal conditions, the fluorescent intensity of CDs increased linearly with increasing concentrations of glucose from 2 to 200 μM, and the detection limit towards glucose was calculated to be 0.83 μM. In addition, the proposed fluorescent assay was successfully applied to the determination of glucose in serum samples with satisfactory results. This proposed fluorescent assay is simple, cost-effective and environmentally friendly, and thereby holding great potential for diabetes management and biosensing applications.
研究领域:
生物化学
·
医学诊断
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产品关联
DOI
高影响因子
MICROCHIMICA ACTA
·
2022
·Vol. 189
·期 3
·1-11
·
IF 6.408
Qiang Yu,Yang Weixia,Zhang Xiaoshuo,Luo Xueli,Tang Wenzhi,Yue Tianli,Li Zhonghong
A nanocomposite was prepared by loading UiO-67 nanoparticles onto porous carbon materials derived from Ce-MOF (Ce-PC) for fluorescence detection of glyphosate. The probe (UiO-67/Ce-PC) exhibits fluorescence emission at 414 nm as the response signal under excitation at 310 nm. The fluorescence enhancement mode of UiO-67 reduces the background interference, and the introduction of Ce-PC provide hierarchical nanostructure and large specific surface area that can increase the contact availability and improve the pre-enrichment effect, ensuring UiO-67/Ce-PC with superior sensitivity. The abundant metal hydroxyl group (M–O-H) of UiO-67/Ce-PC could recognize phosphoryl groups (-PO 3 H 2 ) of glyphosate through ligand exchange, which synergizes with H-bonding interaction and electrostatic attraction to exhibit specificity toward glyphosate. The competitive coordination effects weaken the ligand-to-metal charge transfer (LMCT) and consequently induce the fluorescence recovery. The calibration plot of the fluorescence enhancement response of UiO-67/Ce-PC towards glyphosate was recorded in the range 0.02–30 μg mL −1 with a low limit of detection (LOD) of 0.0062 μg mL −1 , which is superior to the pure UiO-67. In addition, the sensor exhibited high selectivity and satisfactory accuracy and precision with recoveries of 92.1–105.6% and RSDs below 3.4%. This work not only presents a feasible sensor for sensitive and selective determination of glyphosate from cereal samples, but also provides a promising strategy for the design of MOF-based nanocomposites to achieve trace detection of various pollutants. Graphical abstract
研究领域:
分析化学
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环境科学
·
材料科学
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产品关联
DOI
PubMed
高影响因子
LUMINESCENCE
·
2020
·Vol. 35
·期 7
·989-997
·
IF 1.855
Zhu Han,Li He,Shuang Pan,Hui Liu,Xiaoli Hu
A novel and sensitive fluorescence analysis platform was constructed for the detection of chlorogenic acid (CGA) using carbon dots (C-dots) with prominent sensitivity and selectivity. Excitation-dependent emission fluorescence C-dots were fabricated using citric acid and l -histidine as precursors through an efficient one-step hydrothermal treatment. The maximum excitation and emission wavelength of the as-synthesized C-dots were 340 nm and 414 nm, respectively. Moreover, the as-prepared C-dots displayed excellent water solubility and good photostability. The fluorescence quantum yield of the as-prepared C-dots was measured to be about 22% using quinine sulfate as the reference. Furthermore, the obtained C-dots were applied to the detection of CGA accompanied with a wide linear range from 1.53 μmol L −1 to 80.0 μmol L −1 as well as a limit detection of 0.46 μmol L −1 . More importantly, the proposed fluorescence method was successfully used to analyse CGA in coffee and honeysuckle.
研究领域:
分析化学
·
食品科学
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产品关联
DOI
PubMed
高影响因子
MICROCHIMICA ACTA
·
2022
·Vol. 189
·期 5
·1-10
·
IF 6.408
Ding Jinglei,Zhang Wenqi,Xue Fengying,Sun Yu,Yan Quizhu,Chen Yanwei,Shan Guiye
Gold nanoclusters (AuNCs) are widely used in the fluorescence detection of biomolecules in human serum due to their good fluorescence properties, low toxicity, and better biocompatibility. However, the weak fluorescence intensity of AuNCs limits the fluorescence detection of molecules within a wide concentration range. It is reported that coating AuNCs in ZIF-8 with adjustable pore size can effectively improve the fluorescence intensity of AuNCs and broaden the detection range. And the AuNCs wrapped in the gaps of ZIF-8 can prevent the fluorescence quenching caused by the aggregation of AuNCs. However, ZIF-8 has high crystallinity, poor dispersion, and easy deposition, which reduces the fluorescence stability of the detection system and affects the detection. Based on the above research, the highly hydrophilic polymer PEI was modified to the surface of ZIF-8, and a kind of nanocomposite material AuNCs/ChOx@ZIF-8/PEI was obtained by co-encapsulating AuNCs prepared with glutathione as a ligand and cholesterol oxidase (ChOx) into ZIF-8 modified with PEI. The composite material emits strong red light at 650 nm under the excitation of 395-nm light, and the system can sensitively detect cholesterol (Chol) in human serum. Compared with other materials, the PEI-modified composite has better solubility and stability, so the detection effect of Chol is better. Encapsulation of ChOx in the ZIF-8 shell can protect the enzyme and increase the local concentration of ChOx, thereby speeding up the reaction rate. Compared with free AuNCs/ChOx, the quenching rate of AuNCs/ChOx@ZIF-8/PEI system is doubled. Secondly, the addition of Fe 2+ to the detection process results in higher quenching rate and detection sensitivity. The system can detect Chol in the concentration range 0.1–2.4 μM, with a detection limit of 0.073 μM. The determination is a fast and sensitive strategy. In addition, the practicability of this assay in the detection of Chol in human serum has been verified. Due to its selectivity and sensitivity, it has potential application value in clinical diagnosis. Graphical abstract
研究领域:
生物化学
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医学诊断
·
纳米材料科学
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产品关联
DOI
PubMed
高影响因子
NEW JOURNAL OF CHEMISTRY
·
2023
·Vol. 48
·期 4
·1642-1649
·
IF 3.3
Xurong Zuo,Pengfei Liu,Qinhao Sun,Jiahui Huang,Yuwei Zhang,Xuecheng Zhu,Runqi Chen,Xiangyu Meng
Because anthrax spores are highly lethal to humans and animals as well as potential biological warfare agents, there is a great need for rapid, sensitive, and selective quantification of dipicolinic acid (DPA) as a biomarker for anthrax spores. Herein, we prepared a novel lanthanide-doped nanoprobe by coordination of Tb3+ ions with tannic acid (TA)-coated zeolitic imidazolate frameworks-8 (ZIF-8) (ZIF-8@Tb–TA). The proposed assay was derived from the unsaturated coordination of Tb3+ ions. In the presence of DPA, Tb3+ ions could be sensitized to emit inherent luminescence due to the energy transfer after coordination with DPA. The results illustrated that ZIF-8@Tb–TA could be used as a sensitive nanoprobe for detecting DPA with a broad linear range (0 μM to 12.0 μM), and the limit of detection (LOD) was 12.3 nM. Moreover, the specific recognition ability of DPA by ZIF-8@Tb–TA was much better than that of other interfering molecules. This study proposed a new strategy to establish lanthanide-functionalized nanoprobes for highly selective and sensitive detection of DPA.
研究领域:
生物化学
·
分析化学
·
医学检测
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产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）