SENSORS AND ACTUATORS B-CHEMICAL
·
2023
·
IF 8.4
Haineng Bai,Cheng Feng,Hui Guo,Xiaoli Li,Weifeng Liu,Yamin Feng,Kuili Liu,Dunjun Chen,Youdou Zheng,Fuqiang Guo
Monitoring and reducing NO 2 pollution at room temperature is indispensable for human survival. Thus, we propose a light-activated route (UV light, 100 mW/cm 2 ) to realize a high-performance NO 2 detection based on CuO/rGO gas sensor. The CuO/rGO sensor under UV light illumination exhibits a high response of 22.18–100 ppm NO 2 at 23 ℃, which is approximately 1.36 times of the CuO/rGO sensor and 2.31 times of the CuO sensor under dark, respectively. Meanwhile, under UV light illumination, the CuO/rGO sensor has a fast response/recovery speed of 10.9/30.9 s to 20 ppm NO 2 at 23 ℃, which is obviously better than that under dark. Moreover, the light-activated CuO/rGO sensor has excellent repeatability, selectivity, ultra-low detection limit (50 ppb) and long-term stability. The significantly appealing gas-sensing performance of CuO/rGO sensor is mainly ascribed to the mesoporous structure, high specific surface area and plentiful oxygen vacancy of CuO/rGO nanocomposites . More attractively, the photo-generated carriers and formed heterojunction also greatly improve the carrier migration in the context of the NO 2 /CuO/rGO interaction, enhancing the gas-sensing performance of gas sensor. Our work will provide insight in utilizing light illumination to realize ultrasensitive and room-temperature detection of ppb-level NO 2 gas.
研究领域:
材料科学
·
环境科学
✓ 已验证
产品关联
DOI
高影响因子
ACS Applied Energy Materials
·
2024
·
IF 5.4
SocMan Ho-Kimura
Photoactivated bismuth vanadate (BiVO4) anodes are highly promising candidates for solar-driven water splitting. Extant research has shown that prolonged light exposure results in the formation of a borate cocatalyst junction layer on the BiVO4 anode surface, which is attributable to the photocorrosion of BiVO4 and etching modification in a borate electrolyte; consequently, the photocurrent is significantly increased. This study analyzes the effects of light alone on photoactivated BiVO4 anodes in the absence of the borate cocatalyst. We utilized photocorrosion- and etching-resistant BiVO4 to prevent formation of the borate cocatalyst overlayer and investigated the effects of short-duration light irradiation on the photoelectrochemical (PEC) properties. Remarkably, we observed that pretreatment with a mere 20 min of light exposure in both air and electrolyte resulted in a notable increase in the photocurrent. In addition, this photoactivation effect recurred via repeated light irradiation and dark storage. The PEC technique was used to show that the intraband gap states reduced after photoactivation, and hole accumulation increased on the photoactivated BiVO4 surface during the subsequent water oxidation reaction. Furthermore, the spectroelectrochemical spectra revealed that the hole-trapping absorbance of photoactivated BiVO4 decreased. Photoincident absorption spectroscopy and transient absorption spectroscopy further showed an increased population of the photogenerated holes and an extended lifetime on the microsecond time scale, respectively, which contributed to improved PEC water-splitting activity with the photoactivated BiVO4. These findings are expected to offer deeper insights into the trap-filling mechanism underlying BiVO4 photoactivation and its effect on PEC water splitting.
研究领域:
材料科学
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能源转换
·
光催化
✓ 已验证
DOI
高影响因子
Electronics
·
2022
·Vol. 11
·期 19
·3254
·
IF 2.69
Ran Zhang,Qinyi Wang,Ya Chen,Chen Jiao,Fuxi Liu,Junwei Xu,Qiuwei Zhang,Jiantao Zhao,Lida Shen,Changjiang Wang
With the growing emphasis on medical testing, people are seeking more technologies to detect indexes of the human body quickly and at a low cost. The electrochemical biosensors became a research hotspot due to their excellent properties. In this study, dicopper hydroxide phosphate (Cu2(OH)PO4) was incorporated in resin, and the resin sheets were prepared by digital light processing (DLP). The copper base points were activated on the resin sheet surface by Nd: YAG laser and then covered by the electroless copper plating and the electroless silver plating. The laser could effectively activate copper base points on the resin surface. Furthermore, silver electrodes on the detection chips could distinguish glucose solutions of different concentrations well. Finally, a novel detection kit with a three-electrode chip was designed for rapid health testing at home or in medical institutions in the future.Keywords:biosensor;DLP;laser activation;electroless plating;glucose testing
研究领域:
医学检测
·
材料科学
✓ 已验证
DOI
高影响因子
CARBOHYDRATE POLYMERS
·
2024
·
IF 10.7
Yumeng Li,Yongsheng Ni,Wei He,Haoran Li,Wendi Zhang,Lijun Tan,Jinsong Zhao,Baocai Xu
In order to solve the problem of poor adhesion of polysaccharide coatings in meat storage and inconvenient secondary spraying, which leads to poor preservation effect, this study was inspired by the property of mussels to adhere firmly to surfaces and design a bioactive composite coating. Here, curcumin-loaded zein nanoparticles (CZ NPs) were successfully prepared and incorporated into carrageenan-based biocomposite coatings for chilled meat preservation. The prepared curcumin-zein-riboflavin-carrageenan (CZRC) coating featured smooth spherical morphology and the solubility of hydrophobic substances, the adhesion and stability of the composite coating were respectively improved to 3.8 and 6 times compared to CZ NPs. The CZRC coating also shows desirable antioxidant activity (89.78 ± 4.8 % on DPPH and 91.40 ± 2.1 % on ABTS +) and the treatment based on CZRC coating under light irradiation reduced Pseudomonas fragi (by 2.02 log CFU/mL) and Brochothrix thermosphacta (by 4.35 log CFU/mL), which prolonged the shelf life of lamb and pork to 1.8 and 2.3 times at 4 °C storage condition. This work provides a viable strategy for the development of highly adhesive coatings with self-activation enhanced activity to achieve long-lasting preservation.
研究领域:
食品科学
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生物材料学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ACS Nano
·
2025
·
IF 16
Jinyang Liu,Xuebo Zhang,Bingjie Zhao,Huan Ling,Yanzhong Li,Kuangshi Sun,Song Chen,Yanxin Zhang,Tianli Zhai,Yunxiang Zhang,Fuyou Li,Qian Liu
Single-molecule tracking offers nanometer resolution for studying individual molecule dynamics but is often limited by sparse labeling to avoid signal overlap. We present Red-Light-Activated Single-molecule Tracking (RE-LAST) strategy to address this challenge utilizing a photoactivatable probe, SiR670. SiR670 combines traditional silicon rhodamine with a photocage called SO, quenching fluorescence via photoinduced electron transfer (PET). Red light triggers SiR670 excitation, generating singlet oxygen that oxidizes the SO cage, halting PET and restoring fluorescence. RE-LAST used red light for both activation and imaging, eliminating harmful UV exposure. This method enables high-throughput single-molecule tracking, achieving approximately 9 times more tracks than conventional methods and allowing detailed classification of CD56 membrane protein motion. Furthermore, in situ imaging of single live cells revealed the effects of triplet quencher and oxygen scavenging system (OSS) on membrane protein dynamics. While triplet quenchers like Trolox had minimal impact on protein movement patterns, OSS significantly accelerated protein movement and increased the proportion of mobile proteins. This approach provides a comprehensive method for investigating membrane protein dynamics in living cells, contributing to further developments in cellular and molecular biology.
研究领域:
细胞生物学
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分子生物学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF THE MECHANICS AND PHYSICS OF SOLIDS
·
2022
·
IF 5.582
Hang Yang,Xi Chen,Bonan Sun,Jingda Tang,Joost J. Vlassak
Among soft materials, hydrogels with dynamic bonds that can be activated by a range of stimuli including temperature, pH, and infrared or ultraviolet light, constitute a special class of materials with unusual properties such as self-healing, actuation , and controlled degradation. Here, we take a hydrogel with reconfigurable disulfide crosslinks as an example and investigate its mechanical behavior. We demonstrate that this material has excellent fracture and fatigue resistance when the disulfide crosslinks are activated by ultraviolet illumination. We propose a simple constitutive model that describes the mechanical behavior of the material under a broad range of conditions.
研究领域:
材料科学
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生物医学工程
✓ 已验证
产品关联
DOI
高影响因子
MOLECULES
·
2020
·Vol. 25
·期 2
·407
·
IF 3.267
Jiaguo Li,Dian Xiao,Lianqi Liu,Fei Xie,Wei Li,Wei Sun,Xiaohong Yang,Xinbo Zhou
In this article, we report the design, synthesis, photodynamic properties, and in vitro evaluation of photoactivatable prodrug for the poly (ADP-ribose) polymerase 1 (PARP-1) inhibitor Talazoparib. In order to yield a photoactivatable, inactive prodrug, photoactivatable protecting groups (PPGs) were employed to mask the key pharmacophore of Talazoparib. Our study confirmed the good stability and photolytic effect of prodrugs. A PARP-1 enzyme inhibition assay and PARylation experiment showed that the inhibitory activity of the prodrug was reduced 380 times and more than 658 times, respectively, which proved that the prodrug’s expected activity was lost after PPG protection. InBRCA1- andBRCA2-deficient cell lines, the inhibitory activity of the compound was significantly restored after ultraviolet (UV) irradiation. The results indicate that the photoactivatable prodrug strategy is an interesting approach for studying PARP inhibitors. Meanwhile, the described photoactivatable prodrug also provided a new biological tool for the mechanism research of PARP.Keywords:Talazoparib;PARP inhibitor;prodrug;o-nitro-benzyl;photoactivatable protecting groups
研究领域:
药物化学
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肿瘤学
·
生物化学
✓ 已验证
DOI
PubMed
高影响因子
JOURNAL OF HAZARDOUS MATERIALS
·
2024
·
IF 12.2
Xingzhi Jin,Di Gao,Chunyan Zhang,Chen Chen,Yuyue Li,Hao Chen,Peng Cai,Jianwei Li,Xing Ding
Environmental persistent free radicals (EPFRs) derived from chlorophenols, triggered by light or heat exposure, pose significant ecological concerns, yet the impact of chlorine substituents on EPFRs formation and reactivity remains inadequately understood. Through an intentional synthesis of chlorophenol-derived EPFRs with varying chlorine contents and positioning, we elucidated the role of chlorine in the photoactivation of molecular oxygen. Our combined experimental and theoretical analysis reveals that these EPFRs are primarily oxygen-centered phenoxy radicals, establishing a direct link between chlorine substitution patterns and their ability to activate molecular oxygen under visible light. Increased chlorine content enhances EPFRs formation by elevating the positive charge on the phenolic hydroxyl group’s hydrogen atom, facilitating its removal. Moreover, the capability of EPFRs to activate molecular oxygen was directly correlated with chlorine content, with 2,3,5,6-tetrachlorophenol-derived EPFRs showcasing the highest activity. This activity is attributed to their structural propensity for TCSQ ·- species generation. Furthermore, our study established a significant correlation between the toxicity and activity of EPFRs, emphasizing the critical role of halogen substituents in determining the reactivity of EPFRs. These insights contribute to our understanding of their environmental and toxicological ramifications, underscoring the imperative for continued research aimed at mitigating their detrimental impacts.
研究领域:
环境科学
·
毒理学
·
化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Journal of Materials Chemistry C
·
2018
·Vol. 6
·期 7
·1701-1708
·
IF 5.976
Xiaoming Fu,Chi Zhang,Zhiwei Peng,Yong Xia,Jianbing Zhang,Wei Luo,Rui Zhan,Honglang Li,YuHuang Wang,Daoli Zhang
Mesocrystals, which are ordered superstructures composed of crystalline nanoparticles aligned along well-defined crystallographic directions, have recently been investigated for their novel or improved properties for different applications. All-inorganic halide perovskite CsPbX3 materials are believed to be promising materials for next generation optoelectronic devices. In this study, a facile and rapid synthesis of all-inorganic halide perovskite CsPbBr3 mesocrystals at ambient temperature in air is presented, which does not employ dimethylformamide (DMF). The results indicate that ligands have great influences on the growth kinetics and morphologies of CsPbBr3 mesocrystals with standard cubic structure and high luminescense. The destabilization of ligand matrix is responsible for the self-assembly of mesocrystals through oriented attachment into larger monocrystals because of mutual crystallographic orientations of individual building blocks with a defined long-range order on the atomic scale. Furthermore, photoactivation phenomenon was observed in CsPbBr3 mesocrystals and these intrinsic properties may help to understand the nucleation and growth mechanisms of metal-halide perovskites.
研究领域:
材料科学
·
光学
✓ 已验证
产品关联
DOI
高影响因子
RSC Advances
·
2016
·Vol. 6
·期 24
·20366-20373
·
IF 3.289
Yuwei Cong,Zigui Wang,Shasha He,Dongfang Zhou,Jizhen Li,Zhigang Xie,Xuesi Chen,Xiabin Jing,Yubin Huang
Platinum(II) complexes are used for treating over half of cancers in the clinic. However, their application is accompanied with acquired resistance and severe toxic side effects. To address these challenges, a multifunctional single drug constructed from a photo-activated oxaliplatin(IV) complex and DMC was conjugated to polymer to form multifunctional single-drug-loaded nanoparticles. When the nanoparticles are internalized by cancer cells via endocytosis, active oxaliplatin(II) can be released upon UVA irradiation to attack DNA, while DMC will be hydrolyzed subsequently from the polymer chain within the intracellular environment to block DNA repair by PP2A inhibition. The multifunctional single-drug-loaded nanoparticles exhibited enhanced anti-cancer efficacy and decreased toxicity compared to oxaliplatin(II) in vitro and in vivo. This enhanced cancer treatment strategy could have potential clinical use in the near future.
研究领域:
肿瘤学
·
药剂学
·
生物化学
✓ 已验证
产品关联
DOI
高影响因子
ACS Applied Materials & Interfaces
·
2025
·
IF 8.2
Kaimin Zhang,Danman Guo,Tianyi Tang,Xuankun Fang,Faxu Lin,Xiang Long,Fangfang Ke,Xiaoyu Ji,Nipeng Chen,Zhen Zhang,Huahua Huang,Zhenguo Chi,Zhiyong Yang
Recent advancements have focused on developing nanoscale persistent room-temperature phosphorescence (pRTP) structures to expand their applicability in biomedical fields. Traditional fabrication methods typically produce surface-coated core–shell pRTP nanoparticles composed of nonbiocompatible pRTP emitters at very high concentrations in the core. To overcome this limitation, polymeric pRTP nanosystems have been presented in this study as a promising alternative by embedding RTP molecules within the biocompatible polymer matrix, thereby significantly reducing the required concentration of RTP molecules. These polymer nanoparticles were fabricated using a biocompatible poly(lactic acid) (PLA) matrix by an effective microemulsion-based method. They exhibited similar pRTP properties to the traditional nanoparticles, showing comparable long-lasting phosphorescence with a lifetime of 118 ms even when the phosphorescent molecule content is below 2%. Moreover, the pRTP polymer nanoparticles with excellent biocompatibility and stability demonstrate interesting reversible photoactivated pRTP properties. They have been successfully applied for in vivo imaging with a high signal-to-noise ratio (SBR) of 2061, maintaining strong and long-lived phosphorescent emissions even for 20 min. These results highlight a viable approach to advancing the pRTP technology for biological applications.
研究领域:
材料科学
·
生物医学工程
·
影像学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ACS Applied Materials & Interfaces
·
2022
·
IF 10.383
Jianjie Li,Xiaoli He,Huaide Jiang,Yi Xing,Bi Fu,Chengzhi Hu
Advances in the versatile design and synthesis of nanomaterials have imparted diverse functionalities to Janus micromotors as autonomous vehicles. However, a significant challenge remains in maneuvering Janus micromotors by following desired trajectories for on-demand motility and intelligent control due to the inherent rotational Brownian motion. Here, we present the enhanced and robust directional propulsion of light-activated Fe3O4@TiO2/Pt Janus micromotors by magnetic spinning and the Magnus effect. Once exposed to a low-intensity rotating magnetic field, the micromotors become physically actuated, and their rotational Brownian diffusion is quenched by the magnetic rotation. Photocatalytic propulsion can be triggered by unidirectional irradiation based on a self-electrophoretic mechanism. Thus, a transverse Magnus force can be generated due to the rotational motion and ballistic motion (photocatalytic propulsion) of the micromotors. Both the self-electrophoretic propulsion and the Magnus force are periodically changed due to the magnetic rotation, which results in an overall directed motion moving toward a trajectory with a deflection angle from the direction of incident light with enhanced speed, maneuverability, and steering robustness. Our study illustrates the admirable directional motion capabilities of light-driven Janus micromotors based on magnetic spinning and the Magnus effect, which unfolds a new paradigm for addressing the limitations of directionality control in the current asymmetric micromotors.
研究领域:
纳米材料
·
物理化学
·
智能控制
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）