MICROCHIMICA ACTA
·
2021
·Vol. 188
·期 10
·1-10
·
IF 5.833
Zheng Delun,Chen Min,Peng Jingjun,Chen Jiayang,Chen Tufeng,Chen Yaowen,Huang Linjia,Gao Wenhua
HKUST-1 MOFs and its derivative HKUST-CuO were coupled with TiO 2 nanoparticles to form the heterogeneous composites of HKUST-1/TiO 2 and HKUST-CuO/TiO 2 based on their well-suitable bandgap energies (Eg). Compared with mono-component HKUST-1 or HKUST-CuO, the prepared composites displayed photoelectrochemical (PEC) response due to the synergistic effect from their heterogeneous structure. Higher photocurrent response was obtained on HKUST-CuO/TiO 2 -modified ITO electrode (HKUST-CuO/TiO 2 /ITO), which could be attributed to the hollow structure with a thin shell of HKUST-CuO greatly enhancing visible spectra harvesting. The CuO component in HKUST-CuO not only could accelerate electron transfer on the heterojunction interface but also effectively separate the photo-generated charge carriers (e −1 /h + ). Based on the excellent PEC performance of prepared photoactive composite material, under visible-light excitation ( λ ≥ 420 nm) and with a working potential of 0 V (vs. Ag/AgCl), the S1 (probe DNA)/HKUST-CuO/TiO 2 /ITO PEC platform was successfully fabricated for colitoxin DNA detection without using ascorbic acid (AA) as an electron donor. Compared with the analysis results on S1/HKUST-1/TiO 2 /ITO electrode, S1/HKUST-CuO/TiO 2 /ITO displayed a wider linear response range from 1.0 × 10 −6 to 4.0 × 10 −1 nM with a lower detection limit of 3.73 × 10 −7 nM (S/ N = 3), the linear regression equation was Δ I (10 −6 A) =0.5549–0.1858 log ( C S2 /M), which confirmed the HKUST-CuO could improve sensitivity because of its prominent PEC property. The relative standard deviation (RSD) of the PEC sensor for target DNA detection of 2.0 × 10 −4 nM was 7.4%. The proposed DNA biosensor also possessed good specificity and stability. Hence, this reported work was a promising strategy for molecular diagnosis in the bio-analysis field. Graphical abstract
(A) Schematic illustration of the preparation process of the proposed PEC biosensors for colitoxin DNA detection. (B) The preparation process of HKUST-1 and HKUST-CuO.
研究领域:
生物分析
·
材料科学
·
分子诊断
✓ 已验证
DOI
高影响因子
FOOD CHEMISTRY
·
2025
·
IF 9.8
Kun Xu,Rui Xu,Xuejing Liu,Qin Wei
A handily self-powered photoelectrochemical (PEC) sensor is established for acetamiprid (ACE) analysis supported by Cu 3 Mo 2 O 9 /Ag 2 S photoanode and Cs 3 Bi 2 Br 9 /BiOBr photocathode. The band gap structure of Cu 3 Mo 2 O 9 and Ag 2 S is matched which enhanced the electron transfer rate. Photocathode composite is synthesized at the interface of water and oil, and the resulting composite has good stability to water and light. Electrons flowing from the photoanode through the external circuit to the photocathode can combine with photogenerated holes of Cs 3 Bi 2 Br 9 /BiOBr, causing the photoelectrons pass into the solution and react with oxygen, and producing a large photocathode current. With the increase of ACE concentration, the detected photocurrent gradually decreased due to the steric hindrance, and a linear relationship between photocurrent and ACE concentration in the range of 0.001–500 nM. This excellent PEC sensor also performed the great detection stability, selectivity and reproducibility, which can also be applied in practical application for pesticides analysis.
研究领域:
分析化学
·
环境科学
·
食品科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Analytical Methods
·
2024
·
IF 2.7
Lu Zhang,Kun Wang,Feng Zhou,Yuwei Bu,Xiaoyan Yang,Guangming Nie
A sensitive photoelectrochemical (PEC) biosensor for silver ions (Ag+) was developed based on Zn-Co doped C and CdS quantum dots (CdS QDs) nanomaterials. Hydrophobic modified sodium alginate (HMA), which could stabilize and improve the PEC performance of CdS QDs, was also used for the construction of PEC sensors. Specially, Zn-Co doped C, CdS QDs and HMA were sequentially modified onto the electrode surface via the drop-coated method, and the C base rich DNA strand was then immobilized onto the modified electrode. As the C base in DNA specifically recognized Ag+, it formed the C-Ag+-C complex in the presence of Ag+, which created a spatial steric hindrance, resulting in a reduced PEC response. The sensing platform is sensitive to Ag+ in the range of 10.0 fM to 0.10 µM, with a limit of detection of 3.99 fM. This work offers an ideal platform to determine trace heavy metal ions in environmental monitoring and bioanalysis.
研究领域:
环境科学
·
生物分析化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
MICROCHEMICAL JOURNAL
·
2024
·
IF 4.9
Zhichang Ma,Jing Sun,Hemeiling Cai,Junwei Di
A photoelectrochemical (PEC) sensor based on a BiVO 4 semiconductor and gold nanoparticles (AuNPs) was successfully prepared for the sensitive detection of Cr(Ⅵ) ions. The calcination temperature was found to be very important for the PEC properties of BiVO 4 . The BiVO 4 -modified indium tin oxide electrode (ITO/BiVO 4 ) calcined at 300 °C generated a low cathodic photocurrent response under light irradiation. BiVO 4 /AuNPs materials were coupled via electrostatic adsorption to enhance the photoelectric conversion performance of BiVO 4 . The use of self-assembled monolayers (SAMs) to modify electrodes reduce the background current. The developed ITO/BiVO 4 /AuNPs/L-Cys PEC sensor was used to detect of Cr(VI). The Cr(Ⅵ) ion concentrations showed a good linearity between 10 pM and 1 μM with a detection limit of 9.1 pM (S/N = 3). The prepared PEC sensor exhibited high sensitivity, a wide linear range, and good selectivity. This work provides a promising platform for the analytical detection of heavy metal ions.
研究领域:
环境科学
·
分析化学
✓ 已验证
产品关联
DOI
高影响因子
MICROCHIMICA ACTA
·
2019
·Vol. 186
·期 6
·1-8
·
IF 5.479
Zhang Yu,Xu Mengjiao,Gao Pan,Gao Wenkai,Bian Zhenfeng,Jia Nengqin
A photoelectrochemical (PEC) method was developed for the determination of dopamine. It is making use of a composite prepared from gold nanoparticles and TiO 2 (type P25) and placed on a fluorine-doped tin oxide (FTO) electrode. The composites are used for photoelectrical detection with improved electron transfer efficiency for photoproduction and with improved photoelectrical conversion efficiency. This is due to the excellent electrical conductivity and surface plasmon resonance absorption by gold nanoparticles, and also by the photocatalytic effect of TiO 2 . Dopamine binds easily to the surface of the composites and acts as an electron donor. This electrode gives a strongly enhanced photocurrent which increases linearly in the 0.1 to 100 μM dopamine concentration range and has a 23 nM detection limit (at S/ N = 3). The electrode was operated over 15 cycles of light-on and light-off states every 20 s under visible-light illumination, and the sensor indicates good stability. In addition, it is selective over several possible interferents including uric acid, L-cysteine, glutathione, ascorbic acid and glucose.
A new gold/P25 composite-based photoelectrochemical sensing scheme for dopamine is described. Under visible light irradiation, the photocurrent response is increased with the increasing concentration of dopamine (DA).
研究领域:
分析化学
·
生物医学工程
·
材料科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
BIOSENSORS & BIOELECTRONICS
·
2014
·
IF 6.451
Jianxiu Zhang,Liping Tu,Shuang Zhao,Guohua Liu,Yangyun Wang,Yong Wang,Zhao Yue
In this work, low-toxicity fluorescent gold nanoclusters (AuNCs) based photoelectrochemical sensors were developed for H 2 O 2 and glucose detection. Herein, the processes used to fabricate the sensors and the photoelectrochemical performances of the sensors under different conditions were presented. Based on the energy band levels of the AuNCs and electron tunneling processes, a detailed photoelectrochemical sensing model was given. The designed sensors were then used for H 2 O 2 and glucose detection without any extra modification of the AuNCs or complex enzyme immobilization . The results demonstrate that the AuNCs allow for H 2 O 2 sensing based on their capacity for both fluorescence and catalysis. Indeed, it was observed that H 2 O 2 was catalyzed by the AuNCs and reduced by photoinduced electrons derived from excited AuNCs. Furthermore, an enhancement in photocurrent amplitude followed the increase in the concentrations of H 2 O 2 and glucose. The effects of the types of ligands surrounding the AuNCs and the applied potential on the output photocurrent were well studied to optimize the measurement conditions. The sensitivity and LOD of MUA-AuNCs at −500 mV were 4.33 nA/mM and 35 μM, respectively. All experimental results indicated that AuNCs could not only serve as a promising photoelectrical material for building the photoelectrochemical biosensors but as catalysts for H 2 O 2 sensing.
研究领域:
生物医学工程
·
分析化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
·
2022
·
IF 9.221
Jinyun Peng,Xueying Li,Yuxia Liu,Wenfeng Zhuge,Cuizhong Zhang,Yingying Huang
Developing materials with excellent photoelectric activity is critical to improving the sensitivity of photoelectrochemical (PEC) sensors. Herein, we reported a convenience method to synthesize phthalocyanine polymer dots (Pdots), which dope zinc phthalocyanine (ZnPc) into a conjugated polymer poly[(9,9-di- n -octylfluorenyl-2,7-diyl)- alt -(benzo{2,1,3}thiadia-zol-4,8-diyl)] (P8BT). The synthesized materials were characterized by energy dispersive spectrometry (EDS), electrochemical impedance spectroscopy (EIS), fluorescence (FL) spectroscopy, transmission electron microscopy (TEM), ultraviolet-visible diffuse reflectance spectroscopy (UV–vis DRS), and dynamic light scattering (DLS). Then, ZnPc-P8BT-Pdots were modified on an indium tin oxide (ITO) electrode by repeated immersion to develop an ultrasensitive PEC sensor for dopamine (DA) detection. Semiconducting polymers in ZnPc-doped forms exhibit a typical photocurrent reduction in comparison with the original polymers . As the photocurrent was weakened, energy was transferred from the conjugated polymers to ZnPc. The photocurrent intensity of ZnPc-P8BT-Pdots/ITO increases as the concentration of DA increases under blue light irradiation . Under the best experimental conditions, the PEC sensor realized the detection of DA (2.5 nM-125 μM) with a limit of detection (LOD) of 1.69 nM (S/N = 3). Moreover, the ZnPc-P8BT-Pdots/ITO sensor for the detection of DA exhibited superior PEC performance, high sensitivity, rapid response, and favorable stability. This study indicated that ZnPc-P8BT-Pdots possess the promising potential to construct PEC sensors for pharmaceutical analysis.
研究领域:
材料科学
·
分析化学
✓ 已验证
产品关联
DOI
高影响因子
Nanomaterials
·
2023
·Vol. 13
·期 5
·915
·
IF 5.3
Jing-Jing Yang,Ying-Zhuo Shen,Zheng Wang,Bo Zhou,Xiao-Ya Hu,Qin Xu
In this study, β-Bi2O3nanosheets functionalized with bisphenol A (BPA) synthetic receptors were developed by a simple molecular imprinting technology and applied as the photoelectric active material for the construction of a BPA photoelectrochemical (PEC) sensor. BPA was anchored on the surface of β-Bi2O3nanosheets via the self-polymerization of dopamine monomer in the presence of a BPA template. After the elution of BPA, the BPA molecular imprinted polymer (BPA synthetic receptors)-functionalized β-Bi2O3nanosheets (MIP/β-Bi2O3) were obtained. Scanning electron microscopy (SEM) of MIP/β-Bi2O3revealed that the surface of β-Bi2O3nanosheets was covered with spherical particles, indicating the successful polymerization of the BPA imprinted layer. Under the best experimental conditions, the PEC sensor response was linearly proportional to the logarithm of BPA concentration in the range of 1.0 nM to 1.0 μM, and the detection limit was 0.179 nM. The method had high stability and good repeatability, and could be applied to the determination of BPA in standard water samples.Keywords:β-Bi2O3;nanosheet;PEC sensor;bisphenol A;molecularly imprinted
研究领域:
材料科学
·
分析化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ANALYST
·
2023
·Vol. 148
·期 20
·4995-5001
·
IF 4.2
Weixin Li,Xinyang Wang,Lifen Chen,Fang Luo,Longhua Guo,Cuiying Lin,Jian Wang,Bin Qiu,Zhenyu Lin
Two-dimensional (2D) layered MoS2 has good dispersion and adsorption properties, but being a narrow bandgap semiconductor limits its application in photoelectric sensing. In this study, a homogeneous photoelectrochemical sensor based on three-dimensional (3D) ZnO/Au/2D MoS2 is proposed for the ultrasensitive detection of tetracycline (TET). MoS2 is uniformly embedded on the 3D ZnO/Au surface by ordered self-assembly. The physical method of π–π interaction of MoS2 replaces the conventional use of chemically modifying aptamers on the electrode material surface. Under optimal conditions, this method has been successfully applied to the detection of TET in milk, honey, pig kidney and pork samples with reliable results. We believe that this study presents a method for the preparation of sensing carriers and target detection with great potential for application.
研究领域:
分析化学
·
环境科学
·
食品科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
BULLETIN OF THE KOREAN CHEMICAL SOCIETY
·
2019
·Vol. 40
·期 3
·214-219
·
IF 0.602
Jinyun Peng,Wenfeng Zhuge,Yingying Huang,Cuizhong Zhang,Wei Huang
In this study, a new photoelectrochemical (PEC) sensor based on the copper tetraamino-phthalocyanine-modified ITO electrode (CuTAPc/ITO) was designed for the determination of nifedipine. The prepared CuTAPc materials were characterized using UV–Visible spectrophotometry (UVS), Fourier transform infrared spectroscopy (FT-IR), and X-ray diffraction (XRD). Then, the CuTAPc solution was coated on the ITO electrode surface to fabricate a simple PEC sensing platform. Then, the photoelectrochemical behavior of nifedipine at the CuTAPc/ITO electrode was investigated by chronoamperometry under ultraviolet light irradiation. The obtained results indicated that the modified electrode showed a higher response signal than the blank electrode. The photocurrent of CuTAPc/ITO increased with the increasing concentration of nifedipine. The peak photocurrents were linearly dependent on the nifedipine concentration in the range of 0.25–18.0 μmol/L, thereby providing the detection limit of 0.15 μmol/L ( S / N = 3). Due to the good responses for the determination of nifedipine, this sensor can be used as an alternative analysis tool for the detection of nifedipine in various real samples with high sensitivity, low detection limit, and wide linearity range.
研究领域:
分析化学
·
药物分析
·
材料科学
✓ 已验证
DOI
高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
·
2020
·
IF 7.1
Wenbo Sun,Peiling Gao,Jiutao An,Jianan Li,Xinyong Li
Hydrogen sulfide (H 2 S), as both an endogenously gaseous signaling compound and an environmentally hazardous substance, has shown great relevance to human health and ecosystem safety. However, a reliable sensing platform for the facile detection of trace H 2 S is still a challenge to be addressed. Herein, a AgI-TiO 2 nanorods array electrode was fabricated through a hydrothermal method followed by ultrasonic impregnation treatment to construct an ultrasensitive photoelectrochemical H 2 S sensor. The decorated AgI could not only play a significant role in the enhancement of visible light absorbance as a narrow bandgap sensitizer but also contribute to the specific affinity towards sulfide as the recognition unit. In the presence of sulfide, multiple heterojunctions were established in situ due to I − -to-S 2− exchange at the AgI sites, proportionately increasing the photocurrent response of the functionalized PEC electrodes. The designed photoelectrochemical (PEC) sensing platform could achieve the quantitative determination of sulfide in a wide range of 1 ∼ 1000 nM with an effective detection limit of 1.25 nM. Additionally, the detection performances for practical H 2 S-containing waste gas and the biological environment were also evaluated. This work could broaden a new vision of the delicate design of interfaces for ultrasensitive environmental analysis.
研究领域:
环境科学
·
分析化学
·
生物医学工程
✓ 已验证
DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2025
·
IF 13.2
LuLu Cao,Xianqiang Gao,Yunlei Zhou,Shugang Zhang,Miao Zhang,Huanshun Yin
The advanced structural design of semiconductor photoactive materials is the core element to improve the performance of photoelectrochemical (PEC) biosensors. By constructing a BiOIO 3 @Bi 4 O 5 Br 2 Z-Scheme heterojunction with abundant oxygen vacancies to significantly improve the photoelectric conversion efficiency, a sensitively PEC biosensor for MBD2 detection was designed by combining DNA isothermal cycle double amplification technology. Specifically, the chitosan-modified BiOIO 3 @Bi 4 O 5 Br 2 was modified on the surface of ITO electrode. Methylene blue (MB)-DNA was immobilized on due to the covalent reaction of its carboxyl group with the amino group of chitosan, and the excess amino group was blocked with acetaldehyde. In the absence of MBD2, the cleavage activity of HpaII is inhibited due to the retention of cytosine methylation. which triggers ISDPR and large amounts of single-stranded DNA complementary to MB-DNA was produced. After MB-DNA hybridization, Exo III was triggered to assist the MB-DNA hydrolysis cycle, resulting in the drop of MB, causing a decrease in the photoelectric signal. Conversely, in the presence of MBD2, it removed cytosine methylation, triggering HpaII hydrolysis and inhibiting subsequent reactions, so that the MB connected to the electrode is retained and the photoelectric signal is enhanced. The sensor had a detection range from 0.07 to 500 ng/mL with a detection limit of 0.018 ng/mL (3σ). The study also explores the effects of environmental pollutants on MBD2 activity and validated with molecular docking models, offering insights into epigenetic regulation and environmental health assessments. This work underscores the potential of advanced photoactive materials and heterojunction designs in biosensor applications.
研究领域:
生物传感
·
材料科学
·
分子生物学
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）