DYES AND PIGMENTS
·
2018
·
IF 3.767
Zhuo Ye,Chao Xiong,Jian Pan,Dongdong Su,Lintao Zeng
A series of highly photostable, lysosome-targeted BODIPYs with tunable fluorescence from green to the near-infrared region was developed. The probes were found to show an accurate lysosome-targeting ability with high selectivity and high photostability under continuous excitation irradiation. The results show that these lysosome-targeted BODIPYs offer a simple and convenient tool for fluorescence imaging of lysosomes, which will be valuable for understanding the activity and function of lysosomes in related cells.
研究领域:
细胞生物学
·
生物化学
✓ 已验证
DOI
高影响因子
ACS Applied Materials & Interfaces
·
2024
·
IF 8.3
Xiujie Zhao,Yan Ma,Jianhao Di,Yanqi Qiao,Jie Yu,Yongmei Yin,Rimo Xi,Meng Meng
Pyroptosis has been reported to improve the antitumor effect by evoking a more intense immune response and a therapeutic effect. For phototherapy, several photosensitizers have been found to initiate pyroptosis. However, the effect of pyroptosis associated with apoptosis in enhancing the antitumor therapy needs sufficient characterization, especially under long-term treatment. As a NIR photosensitizer, heptamethine cyanines have been discovered for anticancer phototherapy for deep tissue penetration and inherent tumor-targeted capability. However, they are not quite stable for long-term performance. To investigate the effect of pyroptosis along with apoptosis on the anticancer immune responses and phototherapy, here, we chemically modulate the cyanine IR780 to regulate hydrophobicity, stability, and intracellular targeting. Two photosensitizers, T780T-TPP and T780T-TPP-C12, were finally optimized and showed excellent photostability with high photothermal conversion efficiency. Although the cellular uptake of the two molecules was both mediated by OATP transporters, T780T-TPP induced tumor cell death via pyroptosis and apoptosis and accumulated in tumor accumulation, while T780T-TPP-C12 was prone to accumulate in the liver. Ultimately, via one injection-multiple irradiation treatment protocol, T780T-TPP displayed a significant antitumor effect, even against the growth of large tumors (200 mm3).
研究领域:
肿瘤学
·
免疫学
·
药理学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
COLORATION TECHNOLOGY
·
2015
·Vol. 131
·期 6
·439-443
·
IF 1.262
Zongqian Wang,Weiguo Chen,Xuewei Zhou,Chaonan Liu,Keith Millington
Bleached silk is rapidly yellowed by exposure to the ultraviolet radiation present in sunlight. The conventional application of a water-soluble hydroxyphenyl benzotriazole ultraviolet absorber (such as UVFast W) to bleached silk reduces its rate of photoyellowing but has a negative impact on the whiteness of the bleached silk, largely cancelling out the improvements in whiteness achieved during bleaching. Therefore, a series of bleaching processes and aftertreatments using UVFast W on silk were investigated, with the measurement of reflection spectrum, whiteness, yellowness, and strength before and after exposure to ultraviolet radiation. The results show that whiteness of silk treated by oxidation–reduction double bleaching can be increased, and the whiteness of double-bleached silk with 4% UVFast W aftertreatment was even slightly higher than that of the hydrogen-peroxide-bleached silk. After ultraviolet irradiation, double-bleached silk samples with 4% UVFast W treatment resulted in both the highest whiteness and optimum photostability by comparison with unbleached standard silk and hydrogen-peroxide-bleached silk samples with and without 4% UVFast W treatment, and its strength difference was superior to the samples, except for standard silk with 4% UVFast W treatment after exposure to UV radiation for 18 h.
研究领域:
材料科学
·
纺织工程
·
光化学
✓ 已验证
产品关联
DOI
高影响因子
ACS Sustainable Chemistry & Engineering
·
2023
·
IF 8.4
Jianxiang Feng,Yulin He,Xuemei Zeng,Benhao Xiang,Shuyi Chen,Pu Shi,Yuejun Liu
Due to biophenol being inherently antioxidant inefficient and cost intensive, it has no choice but to modify its chemical structure for large-scale applications. Cardanol-heterocyclic amines (BAOs) were prepared by a two-step method based on the intramolecular synergistic antioxidant effects of cardanol and nitrogen-containing heterocycles. Their thermal properties and antioxidant and photostability properties in polylactic acid (PLA) were analyzed. The cardanol-heterocyclic amines exhibited high initial decomposition temperatures as high as 380 °C. In addition, with the addition of 1% content of them to PLA, the tensile strength retention rate remained at 35% after 48 h of photoaging, which was 2–2.5 times higher than that of commercial antioxidant butylated hydroxytoluene (BHT) and remained at 67% after 144 h of thermal-oxidative aging, which was about 2 times higher than that of BHT. Among four cardanol-heterocyclic amines, BAO4 possessed superior photostability and antioxidant properties, presenting an intramolecular synergy between OH, N, and S.
研究领域:
材料科学
·
化学工程
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF ALLOYS AND COMPOUNDS
·
2018
·
IF 3.779
Min Yang,Yongbo Wang,Yingkun Ren,Enzhou Liu,Jun Fan,Xiaoyun Hu
In our study, the synthesis conditions of ternary alloyed ZnCdS quantum dots (QDs) with different Zn/Cd molar ratios were investigated. Our results indicated that the optimal reaction conditions of ZnCdS QDs with various molar ratios were different. The ternary ZnCdS QDs were synthesized by a rather simple, facile, low-cost and effective aqueous synthesis method using air-stable compounds. UV–visible (UV–Vis) absorbance and photoluminescence (PL) emission spectra of the ZnCdS QDs showed a blue shift with the decrease of Cd, indicating the formation of alloyed QDs. The optimal reaction conditions, such as refluxing time and S/(Zn+Cd) molar ratios were different for ZnCdS QDs with different Zn/Cd ratios. The cause of the difference was attributed to the different properties of metal ions. In addition, the investigation on the photostability showed that the as-prepared ternary alloyed QDs had strong light resistance. Therefore, the ternary alloyed QDs with outstanding optical properties and high photostability showed potential biological applications and the results also offered new insights for the synthesis of ZnCdS QDs.
研究领域:
材料科学
·
化学
✓ 已验证
产品关联
DOI
高影响因子
CHEMICAL PAPERS
·
2023
·
IF 2.2
Li Junqian,Xiong Ao,Mao Bingshuang
Inorganic quantum dots (QDs) are used in color displays because of wide photo-absorption and controllable photoluminescence (PL) colors, but their PL stability may be low due to surface defects. To overcome it, we prepared CdTe QDs with different sizes (~ 3.8, 4.4 and 5.0 nm) and poly(glycidyl methacrylate) (PGMA)/CdTe composite films. An increased size of QDs made them emit the green, yellow and red light successively. With an increased PL emission wavelength, the films emitted bright light with various colors. Compared to QDs solutions, the composite films have the almost unchanged fluorescence emission wavelengths (536–612 nm) and high PL intensity. The latter has an improved PL stability under optical and thermal conditions. The green-emitting film maintains ~ 81% of PL intensity after 24 h of photo-irradiation as well as ~ 91% of PL intensity at 120 °C. The green and white light-emitting diode (LED) devices were prepared using composite films, and the fluorescent emissions with bright colors were acquired. This study provides a valuable guideline for preparing the polymer/inorganic quantum dot composite films used in the LED poster display screens with bright stable fluorescence emissions.
研究领域:
材料科学
·
光电技术
✓ 已验证
产品关联
DOI
高影响因子
Advanced Sustainable Systems
·
2024
·
IF 6.5
Quanxin Duan,Yushan He,Xiang Long,Jiayang Wang,Changjian Ni,Shaogui Wu
Carbon dots (CDs) have emerged as versatile fluorescent nanomaterials for diverse applications. The synthesis of CDs from natural products offers a sustainable alternative to chemical methods. This study presents the preparation of green fluorescent CDs (G-CDs) using seafood mushrooms as the carbon source and 5-amino-2-methylphenol as the nitrogen source through a hydrothermal approach. The G-CDs exhibit maximum excitation/emission peaks at 467/519 nm and a high quantum yield of up to 17.2% in ethanol. Additionally, the G-CDs demonstrate excellent photostability, salt tolerance, and chemical stability. The excitation-independent emissions suggest the presence of unique surface-state luminescent centers. The application of the G-CDs as an anti-counterfeiting fluorescent ink is demonstrated. This work highlights the promise of converting natural food sources into high-performance CDs, expanding their utility across various domains including biomedicine, sensing, and security.
研究领域:
材料科学
·
生物医学
·
食品安全
✓ 已验证
产品关联
DOI
高影响因子
Journal of Materials Chemistry B
·
2019
·Vol. 8
·期 4
·736-742
·
IF 5.047
Shuo Guo,Yuanqiang Sun,Xin Geng,Ran Yang,Lehui Xiao,Lingbo Qu,Zhaohui Li
Lysosomes are crucial dynamic organelles which play key roles in different cellular processes such as autophagy, endocytosis and phagocytosis. Thus, long-term and real-time lysosomal imaging is desirable and essential to understand the dynamics and biological functions of lysosomes. Herein, ultra-stable carbon dots (CDs) which have shown many advantages such as pH-independence, high water solubility, good photostability and high biocompatibility for lysosome labeling and long-term tracking were synthesized using a one-pot pyrolysis method via microwave irradiation. Compared with the commercial lysosome probe (LysoTracker™ Deep Red), the fluorescent CDs show superior resistance to photobleaching and the HeLa cells were stably labeled by CDs for over 48 h. In addition, the CDs could stain lysosomes in different cell lines with high specificity and track lysosomal movements. Furthermore, the CDs could stain not only lysosomes in living cells, but also lysosomes in drug-induced apoptotic cells and fixed cells, suggesting that they are suitable for lysosomal tracking under both physiological and toxicological processes. All these excellent properties could be attributable to the ultrastability of CDs, which can be employed for constructing nanoplatforms for other applications such as drug carriers and signal guiders in biological processes. This study provides not only a strategy to synthesize green fluorescent CDs for tracking lysosomes, but also a promising candidate for drug loading and signal guidance of biological processes.
研究领域:
细胞生物学
·
生物材料学
·
医学影像学
✓ 已验证
DOI
PubMed
高影响因子
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY
·
2021
·
IF 4.291
Jian-Bo Chen,Taishan Yan,Chaofeng Wang,Ruixia Gao,Silong Xu,Guijuan Fan,Xueyan Zhao,Yu Liu
The dihydroxylammonium 5,5′-bistetrazole-1,1′-diolate (TKX-50), as an outstanding representative of nitrogen-rich energetic salts, has recently attracted increasing interest due to its excellent performances. However, it is unclear about the photostability and degradation pathways of TKX-50 in aqueous solution. In this paper, the photostability and the degradation process of TKX-50 in aqueous solution have been comprehensively studied for the first time. TKX-50 can keep stable toward visible light. However, it presented a rapid degradation with rate constant of 0.0054 s −1 under 254-nm light irradiation. TKX-50 also demonstrated much faster photodegradation than traditional nitro explosives. Further, degradation products of TKX-50 were analyzed by high-resolution mass spectrum with theoretical calculations. The photodegradation pathways are proposed that 5,5′-bistetrazole-1,1′-diolate (BTO) anion of TKX-50 can been fragmented into the nitrile by losing N 2 and HNO, and then hydroxylammonium (NH 3 OH + ) from TKX-50 reacts with the nitrile through the nucleophilic addition. Besides as a solvent, water also may accelerate the photodegradation of TKX-50 probably by hydrolyzing the intermediary nitrile products. In a word, this study provides comprehensive understanding about the photostability of TKX-50 in aqueous solution, and it is helpful to study the photochemistry of other energetic ionic salts based on BTO.
研究领域:
化学
·
材料科学
✓ 已验证
DOI
高影响因子
CRYSTENGCOMM
·
2022
·Vol. 24
·期 35
·6165-6171
·
IF 3.756
Xinghui Hao,Jinhui Li,Chenguang Wang,Xinghua Zhao,Xin He,Changquan Calvin Sun
Dimetronidazole (DMZ), an veterinary antibiotic, exhibits poor photostability with only 80.38% potency remaining after exposure to illuminance of 4500 lux for 7 days. The photodegradation is accompanied by obvious color change. A 1 : 1 cocrystal of DMZ with saccharine exhibited profoundly improved photostability with 98.95% of DMZ remaining after 7 days under the same light exposure. Thus, this new cocrystal can be used to develop more stable drug products of DMZ.
研究领域:
药学
·
化学
✓ 已验证
DOI
高影响因子
GREEN CHEMISTRY
·
2017
·Vol. 19
·期 15
·3611-3617
·
IF 9.125
Meng Li Liu,Lin Yang,Rong Sheng Li,Bin Bin Chen,Hui Liu,Cheng Zhi Huang
Photoluminescent (PL) carbon dots (CDs) as a new type of carbon nanomaterial have attracted increasing attention owing to their fascinating properties. Herein, we develop a facile, energy-efficient, large-scale route to prepare highly PL CDs with a quantum yield of up to 35.3% at room temperature. These PL CDs can be further separated out into green-emissive amorphous carbon nanodots (CNDs) and yellow-emissive crystalline graphene quantum dots (GQDs) through a silica gel column. Both the as-prepared CNDs and GQDs, even when having the same particle-size distribution and chemical groups, have different degrees of surface oxidation. As characterized by X-ray photoelectron spectroscopy (XPS), the yellow-emissive crystalline GQDs have a much higher surface oxidation degree than that of the green-emissive amorphous CNDs. A further finding is that the characteristic emission peaks of the CDs show an obvious red shift from 518 nm to 543 nm with the increase in the surface oxidation degree, which can be attributed to the decrease in their band gap between the lowest unoccupied molecular orbital (LUMO) and the highest occupied molecular orbital (HOMO). That is, the difference in band gap is closely related to the oxidation degree of the CDs, rather than the particle size or chemical groups. Moreover, the amorphous CNDs are very easily photobleached under 140 W xenon lamp irradiation as compared to the crystalline GQDs, indicating that the photostability is dependent on the crystalline structure of the CDs, which is beneficial for the top-down design and development of suitable CDs for different application purposes.
研究领域:
材料科学
·
纳米技术
✓ 已验证
产品关联
DOI
高影响因子
ChemPlusChem
·
2016
·Vol. 81
·期 12
·1292-1298
·
IF 2.836
Jian He,Chun-Fai Ng,King Young Wong,Weifeng Liu,Tao Chen
Graphical Cellulose in solar cells : The photostability and moisture stability of CH 3 NH 3 PbI 3 solar cells is significantly improved by ethyl cellulose (EC) incorporation (see figure). The hydrogen bonds between EC and CH 3 NH 3 PbI 3 stabilize the crystal structure, which accounts for the stability improvement. Organic–inorganic hybrid perovskite solar cells have achieved high power conversion efficiencies (PCE) of around 22 %, comparable to conventional silicon and thin-film solar cells. However, the poor stability of the perovskite material is one of the significant drawbacks for its practical application. In moderate humidity, the perovskite hydrates and decomposes within hours or a few days, which deteriorates the device efficiency rapidly. Herein, is demonstrated the moisture stability and photostability of CH 3 NH 3 PbI 3 can be greatly improved through the interaction between ethyl cellulose (EC) and perovskite crystals. It is found that the CH 3 NH 3 PbI 3 film with EC incorporation is stable over 5 days in 60 % relative humidity (RH) under ambient indoor light, whereas the conventional CH 3 NH 3 PbI 3 film without EC is degraded in 1 day. After being stored in 60 % RH under ambient indoor light for 2.5 days, the solar cell with EC incorporation shows a PCE decrement from 14.08 % to 8.21 %, whereas that without EC is nearly entirely degraded (PCE=0 %). Nuclear magnetic resonance (NMR) spectroscopy shows that hydrogen bonding between EC and CH 3 NH 3 PbI 3 accounts for the improved moisture stability by stabilizing the crystal structure.
研究领域:
材料科学
·
能源技术
·
化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）