JOURNAL OF BIOACTIVE AND COMPATIBLE POLYMERS
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2019
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IF 1.976
Xin Zhou,Yiwa Pan,Ruihua Liu,Xin Luo,Xianyan Zeng,Dengke Zhi,Jing Li,Quhan Cheng,Ziqi Huang,Hui Zhang,Kai Wang
Electrospun polymer scaffolds are regarded as an ideal tissue engineering scaffold due to similar morphological properties with the native extracellular matrix. Among these, polycaprolactone is widely used to fabricate electrospun fibrous scaffolds due to its excellent biocompatibility, good mechanical properties, and ease of manufacture. However, its low biodegradation rate has a negative influence on its application in tissue engineering scaffold. To address this issue, this study prepared hybrid scaffolds composed of polycaprolactone and polydioxanone (a fast-degrading polyether-ester) via either the blend or co-electrospinning. Subsequently, the structural characteristics, mechanical strength, in vitro/vivo degradation, cellularization, and vascularization of two kinds of hybrid scaffolds were evaluated to decide which method is more suitable for producing tissue engineering scaffolds. The incorporation of polydioxanone increased the mechanical strength of both composite scaffolds. Moreover, co-electrospun scaffolds exhibited improved hydrophilicity compared to blend scaffolds. The results of in vitro and in vivo degradation studies showed that the degradation rate of both composite scaffolds was faster than that of neat polycaprolactone scaffolds due to the incorporated polydioxanone component. Especially in co-electrospun scaffolds, the fast degradation of polydioxanone fiber gave rise to larger pore size, thus leading to faster cellularization and better vascularization compared to blend scaffolds. Therefore, co-electrospinning was demonstrated to be superior to blend electrospinning for the preparation of composite scaffolds. Co-electrospun polycaprolactone–polydioxanone scaffolds may be promising candidates for tissue engineering.
研究领域:
生物材料学
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组织工程学
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医学
✓ 已验证
产品关联
DOI
高影响因子
MATERIALS RESEARCH BULLETIN
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2013
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IF 1.913
Houbao Cao,Pingfan Du,Lixin Song,Jie Xiong,Junjie Yang,Tonghai Xing,Xin Liu,Rongrong Wu,Minchao Wang,Xiaoli Shao
In this paper, core/sheath TiO 2 /SiO 2 nanofibers with tunable sheath thickness were directly fabricated via a facile co-electrospinning technique with subsequent calcination at 500 °C. The morphologies and structures of core/sheath TiO 2 /SiO 2 nanofibers were characterized by TGA, FESEM, TEM, FTIR, XPS and BET. It was found that the 1D core/sheath nanofibers are made up of anatase–rutile TiO 2 core and amorphous SiO 2 sheath. The influences of SiO 2 sheath and its thickness on the photoreactivity were evaluated by observing photo-degradation of methylene blue aqueous solution under the irradiation of UV light. Compared with pure TiO 2 nanofibers, the core/sheath TiO 2 /SiO 2 nanofibers performed a better catalytic performance. That was attributed to not only efficient separation of hole–electron pairs resulting from the formation of heterojunction but also larger surface area and surface silanol group which will be useful to provide higher capacity for oxygen adsorption to generate more hydroxyl radicals. And the optimized core/sheath TiO 2 /SiO 2 nanofibers with a sheath thickness of 37 nm exhibited the best photocatalytic performance.
研究领域:
材料科学
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环境科学
✓ 已验证
产品关联
DOI
高影响因子
Polymers
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2024
·Vol. 16
·期 16
·2328
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IF 4.7
Jiachen Ding,Tingting Li,Xiangyi Wang,Mengyang Li,Tianyu Li,Zhiming Zhang
A functionalized ethylene–vinyl-alcohol (EVOH) nanofibrous membrane (NFM) was fabricated via co-electrospinning H4SiW12O40(SiW12) and EVOH first, and then grafting citric acid (CCA) on the electrospun SiW12@EVOH NFM. Characterization with FT-IR, EDX, and XPS confirmed that CCA was introduced to the surface of SiW12@EVOH NFM and the Keggin structure of SiW12was maintained well in the composite fibers. Due to a number of carboxyl groups introduced by CCA, the as-prepared SiW12@EVOH-CCA NFM can form a high number of hydrogen bonds with CR, and thus can be used to selectively absorb congo red (CR) in aqueous solutions. More importantly, the CR enriched in the NFM can be rapidly degraded via photocatalysis. SiW12in the NFM acted as a photocatalyst, and the hydroxyl groups in the NFM acted as an electron donor to accelerate the photodegradation rate of CR. Meanwhile, the SiW12@EVOH-CCA NFM was regenerated and then exhibited a relatively stable adsorption capacity in five cycles of filtration–regeneration. The bifunctional nanofibrous membrane filter showed potential for use in the thorough purification of dye wastewater.
研究领域:
环境科学
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材料科学
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化学工程
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ACS Applied Nano Materials
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2019
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IF 0
Chunlei Zhang,Ping Wu,Guojuan Liu,Zhigao Zhu,Gaofeng Zeng
Direct oxidation of methanol to high value oxygenated chemicals on V2O5/TiO2 based catalysts is a green alternative to the commercial methods. But the V–Ti based catalysts are challenged by the relatively low reactivity. Herein, we demonstrated a facile and practicable strategy to directly fabricate hollow structure VOx/TiO2 nanofibers (VTO-HNF) through the coelectrospinning and calcination method. The effects of V/Ti ratio on the structure, the surface chemistry and methanol oxidation performance were investigated in detail. VTO-HNFs with appropriate V/Ti ratio have hierarchical structure, large surface area, uniform nanoparticles, narrowed grain sizes, and high dispersions of vanadium. Moreover, both the oxidation properties and the acidities of the catalyst were enhanced due to the high content of surface V4+. The VTO-HNF catalysts featured excellent activities and reliable stability for the selective oxidation of methanol to methyl formate (MF) and dimethoxymethane (DMM). The MF yield reached 90% at 150 °C, which is comparable with the noble metal based catalysts. In situ NAP-XPS investigations suggested that the variable valence of vanadium was involved in the oxidation of methanol.
研究领域:
材料科学
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催化
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化学工程
✓ 已验证
产品关联
DOI
MATERIALS & DESIGN
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2021
·
IF 7.991
Mohammed A. Al-Baadani,Kendrick Hii Ru Yie,Abdullrahman M. Al-Bishari,Bilal A. Alshobi,Zixin Zhou,Kai Fang,Binwei Dai,Yiding Shen,Jianfeng Ma,Jinsong Liu,Xinkun Shen
The rising popularity of co-electrospinning technique in the field of biomaterial has enabled the possibility of combining various polymers, in which they provide the mechanical properties and the bioactivity for each other. Herein, a series of polycaprolactone/gelatin (PCL/Gel) composite membranes were prepared by co-electrospinning, and their biocompatibility and drug-controlled release ability were evaluated in detail for the first time. The addition of Gel significantly enhanced the adhesion and differentiation of osteoblasts, while the addition of PCL significantly improved the mechanical properties. Moreover, the in vitro degradation and drug release results showed that by adjust the PCL fibers amount and size, the degradation of Gel and the release profile of hydrophilic drugs/proteins could be effectively controlled: in the low PCL groups (PCL/Gel-1 & PCL/Gel-4), the Gel nano-fibers dissolved rapidly, resulting in an early explosive release within 1 week; however, with the increase of PCL content, the drug release rate decreased gradually, and the total release period could be extended to over 2 weeks (PCL/Gel-2, PCL/Gel-3 & PCL/Gel-5) or more (PCL/Gel-6). Therefore, the preparation of a controllable drug delivery system with good biological activity by co-electrospinning of PCL and Gel could provide an effective strategy for bone regeneration.
研究领域:
生物材料
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组织工程
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药物递送系统
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生物医学工程
✓ 已验证
产品关联
DOI
高影响因子
Nanoscale
·
2023
·Vol. 16
·期 3
·1135-1146
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IF 6.7
Wei Cheng,Wenling Jiao,Yifan Fei,Zaihui Yang,Xiaohua Zhang,Fan Wu,Yitao Liu,Xia Yin,Bin Ding
The design of three-dimensional ceramic nanofibrous materials with high-temperature insulation and flame-retardant characteristics is of significant interest due to the effectively improved mechanical properties. However, achieving a pure ceramic monolith with ultra-low density, high elasticity and toughness remains a great challenge. Herein, a low-cost, scalable strategy to fabricate ultralight and mechanically robust N-doped TiO2 ceramic nanofibrous sponges with a continuous stratified structure by conjugate electrospinning is reported. Remarkably, the introduction of dopamine into the precursor nanofibers is engineered, which realizes the nitrogen doping to inhibit the TiO2 grain growth, endowing single nanofibers with a smoother, less defective surface. Besides, the self-polymerization process of dopamine allows the construction of bonding points between nanofibers and optimizes the distribution of inorganic micelles on polymer templates. Moreover, a rotating disk receiving device under different rotating speeds is designed to obtain N-doped TiO2 sponges with various interlamellar spacings, further affecting the maximum compressive deformation capacity. The resulting ceramic sponges, consisting of fluffy crosslinked nanofiber layers, possess low densities of 12–45 mg cm−3, which can quickly recover under a large strain of 80% and have only 9.2% plastic deformation after 100 compression cycles. In addition, the sponge also exhibits a temperature-invariant superelasticity at 25–800 °C and a low heat conductivity of 0.0285 W m−1 K−1, with an outstanding thermal insulation property, making it an ideal insulation material for high-temperature or harsh conditions.
研究领域:
材料科学
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纳米技术
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陶瓷
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热工程
✓ 已验证
DOI
高影响因子
Journal of Materials Chemistry B
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2016
·Vol. 4
·期 45
·7259-7269
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IF 4.872
Yaying Sun,Fei Han,Peng Zhang,Yunlong Zhi,Jianjun Yang,Xiaohan Yao,Hui Wang,Chao Lin,Xuejun Wen,Jiwu Chen,Peng Zhao
Massive rotator cuff tears (MRCTs) are difficult to repair because of the retraction and poor mobility of torn tendons. In the current study, co-electrospun dual nano-scaffolds of poly(lactic-co-glycolic acid)/collagen I-polycaprolactone/nanohydroxyapatite (PLGA/Col-PCL/nHA) were fabricated and used to bridge MRCTs of infraspinatus tendons in a rabbit model. PLGA–PCL served as a control. The PLGA or the PLGA/Col sides of the dual scaffolds connected the tendon stumps. The PCL or PCL/nHA side was inserted into the bone tunnel at the insertion of the infraspinatus tendon. Fibroblasts showed higher viability and collagen secretion when seeded on a PLGA/Col scaffold compared to a PLGA scaffold. Osteoblasts seeded on a PCL/nHA scaffold grew better with higher mineralization than on a PCL scaffold. Histologically, collagen regenerated along PLGA scaffolds, but showed poor ingrowth to scaffolds compared with the PLGA/Col group. Newly formed bone was observed on the PCL scaffold, but was less than that on the PCL/nHA scaffold. At 6 weeks post repair, the regenerated tendon in both groups had similar maximum load to failure and ultimate stress but significantly lower stiffness in the PLGA–PCL group and a higher cross-sectional area in the PLGA/Col-PCL/nHA group compared with normal values. At 12 weeks, the maximum failure load, ultimate stress and cross-sectional areas of the regenerated tendon in the PLGA/Col-PCL/nHA group were significantly higher than in the PLGA–PCL and normal groups. The biomechanical properties of the PLGA–PCL group were similar to normal except for a larger cross-sectional area. Our data showed that the co-electrospun dual nano-scaffolds are promising in bridging MRCTs. Doping with Col and nHA further strengthens tissue regeneration.
研究领域:
生物医学工程
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组织工程
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骨科
✓ 已验证
产品关联
DOI
PubMed
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2022
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IF 16.744
Meilian Cao,Yi Hu,Wanli Cheng,Siqi Huan,Tian Bai,Zhaoxuan Niu,Yueyang Zhao,Guichu Yue,Yong Zhao,Guangping Han
Fibrous aerogels have received considerable attentions owing to their high specific surface area and multifunctional applications. However, it remains a huge challenge to prepare multi-structured nanofibrous aerogels using green renewable materials. Herein, lignin-based multi-scale cellular aerogels assembled from co-electrospun nanofibers are successfully constructed. Primarily, by preoxidation of core–shell nanofibers assembled uncrosslinked aerogels, lignin-based pre-oxidized aerogels (LPA) with hierarchically natural wood-tracheid-like structures and porous cell walls are prepared. The LPA exhibits excellent hydrophobicity and high adsorptive capacity for diverse oils and organic solvents (adsorption capacity up to 103 g g −1 ). Furthermore, benefiting from the existence of nitrogen functional groups, LPA can be carbonized to nitrogen-doped carbon aerogels (NCA). The obtained NCA not only inherits cellular structures from LPA but also creates abundant interior porosity of nanofibers due to the vacancy left by degradation of polymer. The NCA is used as electrodes materials of supercapacitors, the multi-channel structures at micro/nano scales of NCA can serve as “highway” for fast transportation of ions and electrons. The symmetrical supercapacitor assembled from it delivers a high energy density of 32 Wh kg −1 . Our study provides a new insight for designing and synthesizing biomass-based multifunctional materials through a low carbon footprint manner.
研究领域:
材料科学
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环境工程
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能量存储
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纳米技术
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）