CHINESE JOURNAL OF POLYMER SCIENCE
·
2016
·Vol. 34
·期 9
·1079-1090
·
IF 1.811
Liu Wei,Zhang Hai-shan,Ji Xiang-ling
The hybrid structures of polystyrene- b -poly(ethylene oxide) (PS- b -PEO) block copolymer and inorganic nanoparticles with good stability and biocompatibility have potential applications in drug delivery and bioimaging. Spherical co-assemblies of PS 120 - b -PEO 318 and oleylamine-capped CdS quantum dots (QDs) are produced successfully in this work by adding water to a mixed common solvent, such as N , N -dimethylmethanamide (DMF)/chloroform, DMF/tetrahydrofuran (THF), or DMF/toluene. The energy dispersive X-ray (EDX) spectrum indicates that QDs are located at the interface between the core and shell of the spherical co-assemblies. The co-assembly process during water addition is traced by transmission electron microscopy (TEM) and turbidity measurement. Spherical co-assemblies are formed through budding from bilayers of the block copolymer and QDs. The morphology of the co-assemblies is related to the miscibility of the QD-dispersing solvents with water and the morphology changes from a spherical to a vesicle-like structure with DMF/toluene. Increasing THF content in the mixed solvent causes morphological transitions from spherical co-assemblies to multi-branched cylinders and micelles where QDs are located in the central core. Increasing chloroform content yields vesicle-like structures with protruding rods on the surface. The mechanism of the morphological transitions is also discussed in detail.
研究领域:
材料科学
·
纳米生物学
✓ 已验证
产品关联
DOI
高影响因子
Nanomaterials
·
2019
·Vol. 10
·期 1
·1
·
IF 4.034
Rui Geng,Juanjuan Yin,Jingxin Zhou,Tifeng Jiao,Yao Feng,Lexin Zhang,Yan Chen,Zhenhua Bai,Qiuming Peng
The construction of heterojunctions provides a promising strategy to improve photocatalytic hydrogen evolution. However, how to fabricate a nanoscale TiO2/g-C3N4heterostructure and hinder the aggregation of bulk g-C3N4using simple methods remains a challenge. In this work, we use a simple in situ construction method to design a heterojunction model based on molecular self-assembly, which uses a small molecule matrix for self-integration, including coordination donors (AgNO3), inorganic titanium source (Ti(SO4)2) and g-C3N4precursor (melamine). The self-assembled porous g-C3N4nanotube can hamper carrier aggregation and it provides numerous catalytic active sites, mainly via the coordination of Ag+ions. Meanwhile, the TiO2NPs are easily mineralized on the nanotube template in dispersive distribution to form a heterostructure via an N–Ti bond of protonation, which contributes to shortening the interfacial carrier transport, resulting in enhanced electron-hole pairs separation. Originating from all of the above synergistic effects, the obtained Ag/TiO2/g-C3N4heterogenous photocatalysts exhibit an enhanced H2evolution rate with excellent sustainability 20.6-fold-over pure g-C3N4. Our report provides a feasible and simple strategy to fabricate a nanoscale heterojunction incorporating g-C3N4, and has great potential in environmental protection and water splitting.Keywords:heterojunction;Ag/TiO2/g-C3N4;Co-assembly;hydrogen evolution
研究领域:
材料科学
·
环境科学
·
光催化
✓ 已验证
DOI
PubMed
高影响因子
ACS Applied Materials & Interfaces
·
2015
·
IF 6.723
Lu Wang,Fuqiang Fan,Wei Cao,Huaping Xu
Reactive oxygen species (ROS) play crucial roles in cell signaling and redox homeostasis and are strongly related to metabolic activities. The increase of the ROS concentration in organisms can result in several diseases, such as cardiovascular diseases and cancer. The concentration of ROS in biologically relevant conditions is typically as low as around tens of micromolars to 100 μM H2O2, which makes it necessary to develop ultrasensitive ROS-responsive systems. A general approach is reported here to fabricate an ultrasensitive ROS-responsive system via coassembly between tellurium-containing molecules and phospholipids, combining the ROS-responsiveness of tellurium and the biocompatibility of phospholipids. By using dynamic light scattering, transmission electron microscopy, scanning electron microscopy, and NMR spectra, coassembly behaviors and the responsiveness of the coassemblies have been investigated. These coassemblies can respond to 100 μM H2O2, which is a biologically relevant ROS concentration, and demonstrate reversible redox properties.
研究领域:
生物化学
·
材料科学
✓ 已验证
DOI
高影响因子
NPG Asia Materials
·
2023
·Vol. 15
·期 1
·1-8
·
IF 9.7
Dong Yangbo,Feng Danyang,Li Wei,Zhang Rui,Dou Shuzhen,Wang Luoqi,Yang Yan,Wang Li,Yang Yang,Wei Feng,Qiao Zhen-An
Gradient porous structures enable the fast capillary-directed mass transport and enhance the chemical reaction rate with optimal efficiency and minimal energy consumption. Rational design and facile synthesis of functional mesoporous materials with sheet structure and gradient mesopores still face challenges of stacked structures and unadjustable pore sizes. Herein, an interfacial co-assembly strategy for gradient mesoporous hollow silica sheets is reported. The modulated oil-water interface allows the assembly of gradient mesoporous silica layers on the water-removable ammonium sulfate crystals. The obtained mesoporous silica layers possess narrow pore size distributions (~2.2 nm and ~6.6 nm). Owing to the good mono-dispersity, sheet structure and proper pore size, the designed gradient mesoporous hollow silica sheets can serve as flexible building blocks for fabricating nanoscale molecule filtration device. Experiments reveal that the obtained nanofiltration device shows remarkable gradient rejection rates (range from 23.5 to 99.9%) for molecules with different sizes (range from 1.2 to 4.4 nm).
研究领域:
材料科学
·
化学工程
✓ 已验证
产品关联
DOI
高影响因子
Advanced Healthcare Materials
·
2024
·
IF 10
Meng-Meng Chen,Han-Wen Tian,Yuan-Qiu Cheng,Yu-Xin Yue,Yu-Chen Pan,Dong-Sheng Guo
Snakebite is a medical emergency that often leads to high mortality and morbidity in tropical and subtropical regions. The diversity in venom composition between various types of snakes necessitates the use of different specific antivenom treatments, which presents clinical and financial challenges in the management of snakebites. Therefore, developing a broad-spectrum antidote to neutralize complex and diverse snake venoms has assumed critical importance. Herein, a broad-spectrum antidote is developed through molecular recognition and coassembly to neutralize four kinds of snake venom toxins, those are three-finger toxin (3FTx), snake venom metalloproteinase (SVMP), phospholipase A 2 (PLA 2 ), and snake venom serine protease (SVSP), which have high abundance and toxicity. The coassembly of sulfonate-modified amphiphilic calixarene (SCA) and amphiphilic cyclodextrin (CD) is employed to neutralize the toxicity of 3FTx, 1,2-dodecanedithiol (DDT) and thioetheramide phosphorylcholine (TEAPC) are introduced through coassembly to neutralize toxicity of SVMP and PLA 2 , respectively, and the nafamostat (NT), which can be loaded through the host-guest complexation, is employed to neutralize toxicity of SVSP. The broad-spectrum antidote, NT@SCA/CD/DDT/TEAPC, effectively neutralizes key toxins from the most medically important cobra and vipers, significantly improving survival rates of poisoned mice. This study conceptually validated the feasibility of broad-spectrum detoxification and also offers a conveniently integrated supramolecular strategy.
研究领域:
医学
·
生物化学
·
药理学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
BIOMACROMOLECULES
·
2018
·
IF 5.738
Wangmeng Hou,Lin Wei,Li Liu,Hanying Zhao
Well-defined polymer–protein bioconjugates are widely used in therapeutics and biocatalysis. One of the challenges in the synthesis of bioconjugates is the efficient separation of the target conjugate molecules from reaction systems. In this research, surface coassembly of polymer brushes and polymer–protein bioconjugates is investigated, and it is demonstrated that the coassembly approach can be applied in the purification of polymer–protein bioconjugates. Bovine serum albumin-poly(N-isopropylacrylamide) (BSA-PNIPAM) bioconjugates were synthesized by the “grafting from” approach, and PNIPAM brushes on silica particles were prepared by the “grafting to” approach. PNIPAM brushes on silica particles are able to coassemble with BSA-PNIPAM at a temperature above the lower critical solution temperature of PNIPAM. Two-layer surface structures with collapsed PNIPAM in the inner layers and BSA in the outer layers are formed on the silica particles. The size of the silica particles and molecular weight of PNIPAM on the bioconjugates exert influences on the coassembly. The coassembly approach can be used in the purification of bioconjugates. After repeated coassembly centrifugation-release cycles, all the BSA-PNIPAM bioconjugates can be removed from the reaction solutions, and the purified bioconjugates are obtained.
研究领域:
材料科学
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生物化学
·
分子生物学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
LUMINESCENCE
·
2020
·Vol. 36
·期 1
·28-34
·
IF 1.855
Fan Zheng,Jun Guo,Abdul Jamil Khan,Pandeng Miao,Feng Zhang
Fluorescent nanostructures have been widely applied to biomedical researches and clinical diagnosis such as biolabeling/imaging/sensing and have even acted as therapy reagents. Peptide-based fluorescent nanostructures attract recent interest from biomedical researchers. Inspired by the natural existence of GHK-Cu complex with a growth factor-like effect in human blood, here we have developed a novel approach for designing nanosensors through the co-assembling of two kinds of biomolecules. By making best use of both π-π stacking between carbon rings and the easy-oxidation property of an important transmitter molecule, dopamine (DA), we successfully built up a supersensitive and robust fluorescent pH nanosensor by co-assembling oxidized DA (DA ox ) with a tripeptide GHK. The GHK-DA ox nanostructures have a quantum yield of 20.82%, which might be the brightest one among all the current co-assembling structures merely through unmodified biomolecules. We envision this approach could open a new avenue for not only hybrid nanostructure construction, but also may inspire the bioengineering of in vivo luminescent probes.
研究领域:
生物医学
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纳米技术
·
化学传感
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ADVANCED MATERIALS
·
2021
·Vol. 33
·期 43
·2103130
·
IF 30.849
Shu-Chuan Mei,Xian-Hong Rui,Liang Li,Gui-Xiang Huang,Xiao-Qiang Pan,Ming-Kun Ke,Zhao-Hua Wang,Han-Qing Yu,Yan Yu
Precise synthesis of porous materials is essential for their applications. Self-assembly is a widely used strategy for synthesizing porous materials, but quantitative control of the assembly process still remains a great challenge. Here, a quantitative coassembly approach is developed for synthesizing resin/silica composite and its derived porous spheres. The assembly behaviors of the carbon and silica precursors are regulated without surfactants and the growth kinetics of the composite spheres are quantitatively controlled. This assembly approach enables the precise control of the size and pore structures of the derived carbon spheres. These carbon spheres provide a good platform to explore the structure–performance relationships of porous materials, and demonstrate their pore structure-dependent performance in catalytic water decontamination. This work provides a simple and robust approach for precise synthesis of porous spheres and brings insights into function-oriented design of porous materials.
研究领域:
材料科学
·
化学工程
✓ 已验证
产品关联
DOI
PubMed
高影响因子
INDUSTRIAL CROPS AND PRODUCTS
·
2025
·
IF 6.2
Tengfei Lu,Ziteng Wang,Xiangyu Zheng,Sheng Wang,Xin Liang,Yuqian Xia,Ying Ma,Tong Wang
Deep eutectic solvents (DESs) have shown great potential in the sustainable fabrication of nanoemulsions. However, co-assembled nanoemulsion systems that integrate both hydrophilic DES (HL-DES) and hydrophobic DES (HB-DES) (referred to as HL/HB-DES-NE) have yet to be reported. In this study, we designed and fabricated a novel HL/HB-DES-NE system and utilized it for encapsulating peppermint essential oil (PMEO). The formulation was systematically optimized, and the resulting HL/HB-DES-NE was characterized for particle size, particle size distribution, encapsulation efficiency, stability, anti-inflammatory activity and antibacterial activity. Firstly, a hydrophobic DES was prepared through eutectic mixing of thymol and polyglyceryl-4-caprate, while a hydrophilic DES was synthesized using betaine and glycerol. The optimal formulation is PMEO/thymol:polyglyceryl-4-caprate (2:1, mol/mol)/betaine:glycerol (1:3, mol/mol)/H₂O [0.275/0.25/0.94/3.76, v/v/v/v] which achieved a particle size of approximately 55.80 nm. The nanoemulsions exhibited good anti-inflammatory and antibacterial activities and maintained remarkable stability, showing no significant changes in particle size, distribution, anti-inflammatory activity and antibacterial activity after 14 days of storage at 4 °C, 20 °C, 37 °C, and 55 °C. The proposed co-assembly strategy, which leverages the unique properties of both hydrophilic and hydrophobic DESs, offers a green alternative to traditional surfactants and provides a flexible and scalable platform for the design of high-performance nanoemulsions. The findings not only provide important theoretical and practical foundations for the development of essential oil-based antimicrobial and anti-inflammatory agents in cosmetics, pharmaceuticals, and industrial applications, but also propose a novel strategy for the development of next-generation DES-based formulations across diverse industries.
研究领域:
药剂学
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纳米技术
·
天然产物化学
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药物递送系统
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抗菌材料
✓ 已验证
产品关联
DOI
高影响因子
Nanomaterials
·
2022
·Vol. 12
·期 9
·1453
·
IF 5.719
Chen Wang,Luyao Feng,Junxiao Liu,Jing Fu,Jinglin Shen,Wei Qi
Au nanocluster (AuNCs)-based luminescent functional materials have attracted the interest of researchers owing to their small size, tractable surface modification, phosphorescence lifetime and biocompatibility. However, the poor luminescence quantum yield (QY) of AuNCs limits their practical applications. Herein, we synthesized a type of AuNCs modified by 4,6-diamino-2-mercaptopyrimidine hydrate (DPT-AuNCs). Furthermore, organic acids, i.e., citric acid (CA) and tartaric acid (TA), were chosen for co-assembly with DPT-AuNCs to produce AuNCs-based luminescent materials with enhanced emission. Firstly, it was found that CA could significantly enhance the emission of DPT−AuNCs with the formation of red emission nanofibers (QY = 17.31%), which showed a potential for usage in I−detection. Then···π/π···π interaction between the CA and the DPT ligand was proposed as crucial for the emission. Moreover, chiral TA could not only improve the emission of DPT-AuNCs, but could also transfer its chirality to DPT-AuNCs and induce the formation of circularly polarized luminescence (CPL)-active nanofibers. It was demonstrated that the CPL signal could increase 4.6-fold in a ternary CA/TA/DPT-AuNCs co-assembly system. This work provides a convenient way to build AuNCs-based luminescent materials as probes, and opens a new avenue for building CPL-active materials by achiral NCs through a co-assembly strategy.
研究领域:
材料科学
·
光学
·
生物医学工程
✓ 已验证
DOI
高影响因子
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
·
2021
·
IF 4.539
Jinglin Shen,Yue Bi,Hao Zhang,Liandi Xu,Jin Feng,Wei Qi
Gold nanoclusters (AuNCs) are a class of promising inorganic-organic hybrid nanomaterials with exceptional photoluminescent properties. The understanding of their photoluminescent mechanism is important for developing functional AuNCs-based materials. In this work, thiobarbituric acid-modified AuNCs (TBA-AuNCs) was prepared and its photoluminescent property was modulated through co-assembly with Ba 2+ . The emission intensity was sharply enhanced with the formation of TBA-AuNCs/Ba 2+ complex. Structural characterization including transmission electron microscopy , scanning electron microscopy and X-ray photoelectron spectroscopy confirmed the hybridization of TBA-AuNCs with Ba 2+ . The pH-dependent photoluminescence as well as zeta potential measurements demonstrated that the ligand to metal charge transfer (LMCT) is crucial for the regulation of emission property of the TBA-AuNCs/Ba 2+ . Based on this special photoluminescent mechanism, the TBA-AuNCs/Ba 2+ complex was employed as a chemical sensor for nitro-substituted aromatic compounds . The emission intensity of TBA-AuNCs/Ba 2+ selectively displayed sharp quenching in response to 2-methyl-4-nitroimidazole among various imidazole derivatives. Simultaneously, the complex also showed high sensitivity toward p -nitroaniline and 2-nitrophenol. Therefore, the developed TBA-AuNCs/Ba 2+ assemblies are potential in detecting the nitro-containing compounds, which will find applications in pharmaceutical analysis, environmental protection and other related fields.
研究领域:
材料科学
·
分析化学
·
环境科学
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF MOLECULAR LIQUIDS
·
2023
·
IF 6
Chen Wang,Yanyu Li,Xinmeng Liu,Jing Fu,Jinglin Shen,Wei Qi
Gold nanoclusters (AuNCs) with ultrasmall size have attracted enormous interest due to their unique luminescent properties. Especially, luminescent AuNCs-based hydrogel with three-dimensional (3D) structures is valuable. Herein, hydrogel with effective enhancement of emission (QY increased from 0.45% to 14.6%) is reported through the co-assembly of AuNCs stabilized by 4,6-diamino-2-pyrimidinethiol (DPT) with citric acid (CA) and Al 3+ . With the formation of hydrogel, the microstructures of DPT-AuNCs changed from nanofibers into microdisks. X-ray photoelectron spectroscopy (XPS), photoluminescence (PL) spectra and Fourier transform infrared (FT-IR) reveal that CA is crucial for the emission enhancement of NCs and Al 3+ is benefit for the gelation of NCs. Furthermore, the obtained luminescent hydrogel could be used as a selective sensor for Fe 3+ /ascorbic acid (AA) through the “switch off/on” of luminescence and may find an application in information security. This study offers a convenient strategy for building AuNCs-based luminescent hydrogel through co-assembly method, and presents potential applications as functional materials.
研究领域:
材料科学
·
分析化学
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）