Journal of Energetic Materials
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2017
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IF 1.557
Xi Li,Qiu-han Lin,Xin-Ying Zhao,Zhi-Wei Han,Bo-liang Wang
Thermal techniques (differential scanning calorimetry (DSC) and the vacuum stability test (VST)), according to STANAG 4147, and non-thermal techniques (Fourier transform infrared (FTIR) spectrometry and X-ray diffractometry (XRD)) were used to examine compatibility issues for 2,4,6,8,10,12-hexanitrohexaazaisowurtzitane (CL-20) with a selection of insensitive explosives, including nitroguanidine (NQ), 2,4,6-trinitrotoluene (TNT), 2,6-diamino-3,5-dinitropyridine-1-oxide (ANPyO), 2,4,6-triamino-1,3,5-trinitrobenzene (TATB), 3-nitro-1,2,4-triazol-5-one (NTO) and 2,6-diamino-3,5-dinitropyrazine-1-oxide (LLM-105). DSC measurements showed that ANPyO, TATB, NTO and LLM-105 were compatible with CL-20. The compatibility of CL-20/NQ, CL-20/TNT, CL-20/ANPyO, CL-20/TATB, CL-20/NTO and CL-20/LLM-105 mixtures was further explored using the VST, which revealed that all the selected insensitive explosives were compatible with CL-20. Possible chemical interactions were suspected for CL-20/TATB from the FTIR results and for CL-20/NTO from XRD analysis. In summary, ANPyO and LLM-105 demonstrated the optimal compatibility with CL-20.
研究领域:
材料科学
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化学工程
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爆炸物研究
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DOI
高影响因子
JOURNAL OF ORGANIC CHEMISTRY
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2022
·
IF 4.198
Jun Xu,Chao Peng,Bolin Yao,Hua-Jian Xu,Qiang Xie
This report describes a method for the deoxyfluorination of alcohols with KF as the fluorine source via in situ generation of highly active CF3SO2F. Diverse functionalities, including halogen, nitro, ketone, ester, alkene, and alkyne, are well tolerated. Mild conditions, a short reaction time, and a wide substrate scope make this method an excellent choice for the construction of C–F bonds.
研究领域:
有机化学
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合成化学
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DOI
PubMed
高影响因子
Microsystems & Nanoengineering
·
2024
·Vol. 10
·期 1
·1-11
·
IF 7.3
Ren Guoqiang,Zhang Mingxuan,Zhuang Liping,Li Lianhui,Zhao Shunying,Guo Jinxiu,Zhao Yinchao,Peng Zhaoxiang,Lian Jiangfan,Liu Botao,Ma Jingyun,Hu Xiaodong,Zhang Zhewei,Zhang Ting,Lu Qifeng,Hao Mingming
The exploration of multi-dimensional brain activity with high temporal and spatial resolution is of great significance in the diagnosis of neurological disease and the study of brain science. Although the integration of electroencephalogram (EEG) with magnetic resonance imaging (MRI) and computed tomography (CT) provides a potential solution to achieve a brain-functional image with high spatiotemporal resolution, the critical issues of interface stability and magnetic compatibility remain challenging. Therefore, in this research, we proposed a conductive hydrogel EEG electrode with an asymmetrical bilayer structure, which shows the potential to overcome the challenges. Benefiting from the bilayer structure with different moduli, the hydrogel electrode exhibits high biological and mechanical compatibility with the heterogeneous brain-electrode interface. As a result, the impedance can be reduced compared with conventional metal electrodes. In addition, the hydrogel-based ionic conductive electrodes, which are free from metal conductors, are compatible with MRI and CT. Therefore, they can obtain high spatiotemporal resolution multi-dimensional brain information in clinical settings. The research outcome provides a new approach for establishing a platform for early diagnosis of brain diseases and the study of brain science.
研究领域:
神经科学
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医学成像
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生物医学工程
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材料科学
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DOI
PubMed
高影响因子
COLLOIDS AND SURFACES B-BIOINTERFACES
·
2012
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IF 3.456
Miao Wang,Jiang Yuan,Xiaobo Huang,Xianmei Cai,Li Li,Jian Shen
Grafting-from has proven to be a very effective way to create high grafting densities and well-controlled polymer chains on different kinds of surfaces. In this work, we aim to graft zwitterionic brush from cellulose membrane (CM) via ARGET-ATRP (Activator Regenerated by Electron Transfer ATRP) method indirectly for blood compatibility improvement. Characterization of the CM substrates before and after modification was carried out by attenuated total reflection Fourier transform infrared spectroscopy (ATR-FTIR), water contact angle measurements, X-ray photoelectron spectroscopy analysis, and atomic force microscopy, respectively. The results demonstrated zwitterionic brushes were successfully grafted on the CM surfaces, and the content of the grafted layer increased gradually with the polymerization time. The platelet adhesion, hemolytic test and plasma protein adsorption results indicated the cellulose membrane had significantly excellent blood compatibility featured on lower platelet adhesion and protein adsorption without causing hemolysis. The functionalized cellulose substrate could have a great potential usage for biomedical applications.
研究领域:
生物材料学
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医学工程
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产品关联
DOI
PubMed
高影响因子
Gels
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2023
·Vol. 9
·期 7
·558
·
IF 4.6
Yu Fu,Qingrong Wu,Wanying Yang,Jiaqi Wang,Zechen Liu,Hao Shi,Shouxin Liu
Medical titanium alloy Ti-6Al-4V (TC4) has been widely used in the medical field, especially in human tissue repair. However, TC4 has some shortcomings, which may cause problems with biocompatibility and mechanical compatibility in direct contact with the human body. To solve this problem, physical gels are formed on the surface of TC4, and the storage modulus of the formed physical gel matches that of the human soft tissue. 2-bromoisobutyryl bromide (BIBB) and dopamine (DA) were used to form initiators on the surface of hydroxylated medical titanium alloy. Different initiators were formed by changing the ratio of BIBB and DA, and the optimal one was selected for subsequent reactions. Under the action of the catalyst, L-lactide and D-lactide were ring-opened polymerized with hydroxyethyl methacrylate (HEMA), respectively, to form macromolecular monomers HEMA-PLLA29and HEMA-PDLA29with a polymerization degree of 29. The two macromolecular monomers were stereo-complexed by ultrasound to form HEMA-stereocomplex polylactic acid (HEMA-scPLA29). Based on two monomers, 2-(2-methoxyethoxy) ethyl methacrylate (MEO2MA) and oligo (ethylene oxide) methacrylate (OEGMA), and the physical crosslinking agent HEMA-scPLA29,physical gels are formed on the surface of TC4 attached to the initiator via Atom Transfer Radical Addition Reaction (ATRP) technology. The hydrogels on the surface of titanium alloy were characterized and analyzed by a series of instruments. The results showed that the storage modulus of physical glue was within the range of the energy storage modulus of human soft tissue, which was conducive to improving the mechanical compatibility of titanium alloy and human soft tissue.Keywords:hydrogels;medical titanium alloy;dopamine;mechanics
研究领域:
生物材料学
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医学工程
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DOI
PubMed
高影响因子
CERAMICS INTERNATIONAL
·
2024
·
IF 5.1
Chun Tong,Xinlei Shen,Xia Feng,LiFeng Ding,Haikui Zhu,Lixi Wang
Ca 1- x Sr x B 2 O 4 ( x = 0–0.5) ceramics are prepared using the conventional solid-state method, and their crystal structure, microstructure, microwave dielectric properties, and low-temperature co-firing characteristics are systematically studied. To enhance the crystalline structure order, this study aims to improve the sintering performance of CaB 2 O 4 by forming a solid solution with Sr 2+ substituting Ca 2+ sites. X-ray diffraction results indicate that with the doping of Sr 2+ , the unit cell volume of Ca 1- x Sr x B 2 O 4 ceramics increases, and the diffraction peaks shift to lower angles. EDS results confirm that Sr 2+ is uniformly distributed in the Ca 1- x Sr x B 2 O 4 ceramics, successfully forming a solid solution. SEM analysis reveals that an appropriate amount of Sr 2+ improves grain uniformity and reduces porosity between grains. Raman spectroscopy shows that moderate Sr 2+ doping enhances the order of the crystalline structure, leading to an increase in the Q × f value of the ceramics. When x = 0.03 and the sintering temperature is 900 °C, Ca 1- x Sr x B 2 O 4 ceramics exhibit optimal microwave dielectric properties: ε r = 5.53, Q × f = 33,135 GHz, τ f = −27.37 ppm/°C. During co-sintering with Ag electrodes, Ca 1- x Sr x B 2 O 4 ceramics show excellent chemical compatibility with Ag powder, with no silver diffusion observed. This demonstrates the great potential of Ca 1- x Sr x B 2 O 4 ceramics for LTCC applications.
研究领域:
材料科学
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电子工程
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DOI
高影响因子
Journal of Physical Chemistry C
·
2019
·
IF 4.309
Keyang Yin,Dandan Lu,Liping Wang,Quanxin Zhang,Junying Hao,Gaozhan Li,Hongguang Li
In the preparation of carbon dots (C dots) through pyrolysis, organic molecules with multiple functional groups are popular, and monosubstituted compounds, such as aliphatic amines, are used only as an auxiliary component. Here, we provide a strategy to transfer aliphatic amines and aliphatic aldehydes to C dots in the absence of any other reagent under mild conditions. In a typical experiment, C dots were facilely obtained by refluxing dodecylamine (C12–NH2) in chlorobenzene, which shows blue emission with wavelength-dependent characteristics. The C dots are soluble in a variety of organic solvents and can be further processed by either gel permeation chromatography or silica gel column chromatography, which gives highly pure C dots with absolute fluorescence quantum yield over 10%. The C dots are photoluminescent in the solvent-free state and can be used as fluorescent ink. They are also compatible with polymers such as poly(methyl methacrylate) and polydimethylsiloxane. Influence of the type of functional group was checked. Blue-emitting C dots were obtained as well by refluxing dodecanal in chlorobenzene, but using a compound bearing a carboxylic or hydroxy group only showed little success.
研究领域:
材料科学
·
化学
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DOI
高影响因子
PHYTOMEDICINE
·
2019
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IF 4.18
Shuai Ji,Dan-dan He,Zhen-yu Su,Yan Du,Yu-jie Wang,Shi-kai Gao,Meng-zhe Guo,Dao-quan Tang
Background Herbal compatibility of compound formulas can enhance therapeutic effects or reduce side effects of the monarch drugs , but majority of compatibility mechanisms are still unknown. Sangju-Yin, a well-known Chinese compound formula, is currently used to treat common cold in clinical. Purpose In this study, we proposed a strategy to explore the compatibility mechanism of Sangju-Yin by investigating P450 enzymes-based metabolic interactions between monarch drugs and the other constituent herbs. Methods Under the guidance of traditional Chinese medicine theory, the constituent herbs of Sangju-Yin were divided into four groups, including monarch drugs, monarch drugs with addition of minister drugs, monarch drugs with addition of minister and adjuvant drugs, as well as the whole recipe, namely monarch drugs with addition of minister, adjuvant and conductant drugs. Their effects on rats in vivo P450 (CYP1A2, CYP2A3, CYP2C6, CYP2C11 and CYP3A1) activities after oral administration were evaluated using probe drug assay based on LC-MS/MS. Moreover, effects of the four groups of herbs on mRNA expression of P450 enzymes after oral administration, as well as in vitro P450 activities after co-incubation, were investigated to explore the underlying mechanisms. Results Comparing with monarch drugs, addition of different constituent herbs significantly enhanced CYP1A2 and CYP2C6 activities, and inhibited CYP2A3 and CYP3A1 activities, indicating their possible influences on plasma concentrations of active constituents in the monarch drugs. Mechanism study suggested that these herbs affected P450 activities by transcriptional regulation and/or direct interaction with the enzymes. Conclusion This study clarified the compatibility mechanism of Sangju-Yin from the aspect of P450 enzymes-based metabolic interactions, which would benefit better understanding of the therapeutic basis of Sangju-Yin.
研究领域:
中药学
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药物代谢
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分子生物学
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DOI
PubMed
高影响因子
JOURNAL OF MATERIALS SCIENCE-MATERIALS IN ELECTRONICS
·
2020
·Vol. 31
·期 16
·13496-13502
·
IF 2.22
Fang Weishuang,Ao Laiyuan,Tang Ying,Li Jie,Xiang Huaicheng,Zhang Zhiwei,Du Qianbiao,Fang Liang
Recently, there have been considerable interests in the Li-containing spinel oxides as promising microwave dielectric materials. Li loss at elevated temperatures, however, is known to be inevitable, resulting in deterioration on dielectric performances. Here the influence of Li nonstoichiometry on the microwave dielectric properties of Li 2 ZnGe 3 O 8 , a spinel oxide, was reported. An appropriate level of Li excess enhanced the densification of Li 2 ZnGe 3 O 8 and increased dielectric performances. In contrast, high level of Li excess induced the formation of the secondary phase of Li 2 ZnGeO 4 confirmed by XRD and Raman spectra, which in turn lowered the dielectric properties. Typically, a composition with x = 0.075, in the Li 2(1+ x ) ZnGe 3 O 8 ceramics exhibited the enhanced microwave dielectric properties with ε r = 10.68, Q × f = 77,300 GHz (at 13.3 GHz), and τ f = − 70.35 ppm/°C when sintered at 940 °C for 4 h. Moreover, these compounds have well chemical compatibility with the silver electrodes.
研究领域:
材料科学
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陶瓷学
·
电子材料
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DOI
高影响因子
JOURNAL OF ORGANIC CHEMISTRY
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2022
·
IF 4.198
Lei Xu,Zheng Dong,Qi Zhang,Ning Deng,Shi-Yu Li,Hua-Jian Xu
The versions of Miyaura borylation and protoboration of alkynes catalyzed by low loadings of palladium (400 mol ppm = 0.04 mol %) have been developed. These transformations have a broad substrate scope, good functional-group compatibility, and gram-scale synthetic ability.
研究领域:
有机化学
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催化化学
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DOI
PubMed
高影响因子
Journal of Materials Chemistry C
·
2023
·Vol. 11
·期 5
·1754-1763
·
IF 6.4
Yang Xu,Gengping Wan,Lingling Ma,Ying Zhang,Yanran Su,Disheng Liu,Guizhen Wang
With the explosive development of modern military detection technology, stealth compatibility for materials with both outstanding microwave absorption (MA) and low infrared emissivity is urgently needed. In this paper, indium tin oxide (ITO) nanoparticles with high-efficiency MA and infrared stealth properties were successfully prepared by a steerable method using metal chloride salts as indium and tin sources, and the influence of tin proportion on their structure and properties was discussed. The prepared ITO nanoparticles possessing abundant carriers and defects are beneficial to construct a suitable conductive network, and the polarization process is enhanced by the existence of homogeneous and heterogeneous interfaces, so that strong absorption is generated. Remarkably, the obtained ITO with a single dielectric loss type can realize an effective absorption bandwidth (EAB) of 4.88 GHz with a matching thickness of 2.8 mm. In addition, ITO-5 has the lowest infrared emissivity (0.62) in the range of 3–14 μm, while ITO-10 exhibits the best infrared/radar compatible stealth effect. The lowest reflection loss and the widest EAB for ITO-10 are respectively −20.07 dB and 3.83 GHz, while the infrared emissivity is 0.64. Therefore, ITO shows a broad application prospect in anti-detection, and provides an option for multispectral compatible stealth materials.
研究领域:
材料科学
·
军事技术
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产品关联
DOI
高影响因子
ORGANIC PROCESS RESEARCH & DEVELOPMENT
·
2024
·
IF 3.1
Shichun Weng,Juan Zhou,Yingtao Tian,Xigui Jiang,Rong Chen,Jinyao Hu,Zichao Guo,Liping Chen,Wanghua Chen
In this article, a mixture of sulfuric acid and 50% hydrogen peroxide solution was used to produce Caro’s acid, which serves as an oxidant frequently encountered in the fine chemical industry. The chemical compatibility between 50% H2O2/H2SO4 and organic solvents is an important safety issue. The compatibility of 50% H2O2/H2SO4 and several organic solvents, including ethanol, acetonitrile, ethyl acetate, DMF, dichloroethane, DMSO, ether, and toluene, was studied by reaction calorimetry and thermal analysis techniques. It was found that the first five solvents presented good compatibility with 50% H2O2/H2SO4. DSC tests indicated that these five solvents almost did not react with 50% H2O2/H2SO4 before the onset decomposition temperature of 50% H2O2/H2SO4 (∼93.3 °C). RADEX tests showed that the reactions of 50% H2O2/H2SO4 with these solvents released heats from 800 to 1100 J g–1, and the pressure effect was obvious for these mixtures. In contrast, the last three solvents, namely, DMSO, ether, and toluene, were incompatible with 50% H2O2/H2SO4, exhibiting a significant exothermic signal at lower temperatures. Most interestingly, the mixture of DMSO and 50% H2O2/H2SO4 presented a thermal runaway phenomenon below 40 °C. The causes of this thermal runaway incident were confirmed to be the oxidation of DMSO by Caro’s acid. Reaction calorimetry tests also indicated that the oxidation rate of DMSO was fast even at 40 °C, and the adiabatic temperature rise for the oxidation of DMSO was higher than 400 K.
研究领域:
化学工程
·
安全科学
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产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）