To address the issues caused by ice accretion, researchers have made various attempts to obtain anti-icing surfaces, among which superhydrophobic surfaces have been approved to be an ideal candidate for anti-icing applications. Although extensive research has been conducted to date, the relationship between the anti-icing performance and the anti-condensation performance of superhydrophobic surfaces has yet to be investigated. In this study, superhydrophobic coatings with different surface microstructures were prepared. Tuning of surface morphology was conducted by controlling molar ratio of SiO 2 nanoparticles and polyester powders. The superhydrophobic coatings with uniform surface microstructures exhibit anti-condensation performance. Superhydrophobic coatings with cavities-pore combined surface structures demonstrated superior anti-icing performance to other coatings. The relationship between the anti-icing and anti-condensation performance was investigated. It is verified that the anti-condensation performance of the superhydrophobic surface do not have a simple correlation with the anti-icing performance. Furthermore, the coatings present oil repellency, durable superhydrophobicity and anti-fouling properties.
Cryosurgery is a minimally invasive treatment that utilize extreme low temperatures to destroy abnormal tissues. The clinical monitoring methods for cryosurgery are almost based on the visualization of the iceball. However, for a normal cryosurgery process, the effective killing region is always smaller than the iceball. As a result, the end of the cryosurgery process can only be judged by the surgeons according to their experience. The subjective judgement is one of the main reasons for poor estimation of tumor ablation, and it sparks high probability of recurrence and metastasis associate with cryosurgery. Being different from the previous optimization studies, we develop a novel approach with the aid of nanoparticles to enlarge the effective killing region of entire iceball, and thus it greatly decrease the difficulty of precise judgement of the cryosurgery only by applying the common clinical imaging methods. To verify this approach, both the experiments on a tissue-scale phantom with embedded living HepG2 cells in agarose and on a cell-scale cryo-microscopic freeze-thaw stage are performed. The results indicate that the introduction of the self-synthesized Fe 3 O 4 nanoparticles significantly improved cell killing in the cryosurgery and the range of killing is extended to the entire iceball. The potential mechanism is further revealed by the cryo-microscopic experiments, which verifies the presence of Fe 3 O 4 nanoparticles can significantly enhance the probability of intracellular ice formation and the cell dehydration during freezing hence it promote precise killing of the cells. These findings may further promote the widespread clinical application of modern cryosurgery.
危险品化学品经营许可证（带存储）